Research News from CHOP

CHOP Researchers Refine Understanding of Fetal Hemoglobin Regulation
CHOP researchers have discovered a new part of the regulatory cascade responsible for silencing fetal hemoglobin in adult cells.
Children’s Hospital of Philadelphia Receives $400,000 Grant from American Heart Association to Study Hormones Related to Cardiovascular Disease and Metabolic Health
Aligned with CHOP and AHA’s shared mission to improve cardiac care, grant supports research aiming to discover new hormones secreted from the heart.
Study Finds Newly Formed “Immature” Neurons Appear in Brain Throughout Lifespan
CHOP neurosurgeons collaborated with researchers from the University of Pennsylvania School of Medicine to confirm the presence of these neurons from birth through age 92.
CHOP-led Study Finds Daycare Linked to Increased Complications in Preterm Children with Chronic Lung Disease
Researchers found daycare attendance was associated with increased emergency department visits, steroid use, and chronic respiratory symptoms in preterm children with chronic lung disease.
CHOP Concussion Expert Leads New Policy Statement on Vision Disorders After Head Injuries
A new policy statement on vision disorders after head injuries from the American Academy of Pediatrics is supported by leading ophthalmology organizations.
CHOP Researchers Develop Algorithm to Help Distinguish ADHD Symptoms from Related Conditions
The algorithm could lead to better clinical trials and more targeted treatment.
CHOP Researchers Reveal Cellular and Molecular Mechanisms of Skull Formation
CHOP researchers have identified genes involved in skull development and created an “atlas” that describes how cell types participate in that process.
Study Shows Link Between Cyberbullying and Suicidality in Early Adolescence
Researchers at Children’s Hospital of Philadelphia found that targets of cyberbullying were more likely to report suicidal thoughts and attempts, above and beyond offline bullying.
CHOP Researchers Uncover Molecular Basis of Antigen Processing for Cancer Target MR1
CHOP researchers have revealed the molecular mechanics of a cell-surface molecule that is a potential immunotherapy target.
CHOP Researchers Join Global Team to Take on Solid Tumors in Children
Four CHOP researchers are part of a world-class research team that will receive $25 million to study solid tumors in children, funded by Cancer Grand Challenges.