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FDA Approves Drug for Rare Form of Pediatric Cancer
The FDA has approved a treatment that targets ALK mutations in relapsed, refractory ALK-positive anaplastic large cell lymphoma.
CHOP Researchers Win Science Center Award to Develop AML Treatment
The $200,000 award will fund research to develop a novel therapeutic that ignites the immune system and could act as a stand-alone treatment, as well as boost the effectiveness of existing immunotherapies.
AML Immunotherapy Trial Opens
CHOP has opened a phase 1 trial using CAR T for tough acute myeloid leukemia, hoping to replicate the therapy’s success for acute lymphoblastic leukemia.
Humanized CD19: CAR-T Immunotherapy for First Relapse of ALL in Down Syndrome Patient
An alternative, humanized CD19 CAR T product for first relapse of pediatric ALL is being evaluated in a clinical trial at Children's Hospital of Philadelphia.
CHOP Scientists Report How Some Cancer Cells Develop Resistance to CAR T-cell Therapy
CHOP researchers analyze how some cancer cells resist a groundbreaking cellular therapy, and have found clues to overcoming that resistance.
No More Kids with Cancer Awards $220,000 to CHOP
The $220,000 award will be directed to a Phase I clinical trial that will investigate the effectiveness of CAR T-cell therapy to treat AML.
Advancing the Field of Cell Therapy
A bone marrow transplant saved Kaleo’s life. Today, he’s a dancing machine. His success story is an example of CHOP’s expertise in the field of cellular therapy.
Shortened Inpatient Stays Benefit Certain Leukemia and Lymphoma Patients
Thanks to a recent initiative at CHOP, patients newly diagnosed with B-cell and T-cell ALL, and lymphoblastic lymphoma, now go home on average 9 days after diagnosis — that's 3 weeks sooner than previous stays.
Hodgkin Lymphoma: Minimizing Late Effects, Long-term Risks
With the majority of Hodgkin lymphoma patients surviving their disease, the focus has turned to minimizing the long-term effects of treatment while maintaining excellent cure rates.
Fellow’s Corner: An Excellent Teacher
Charles Phillips, MD, a CHOP fellow, recounts his experience caring for a cancer patient and the many firsts it brought to the both of them.