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Children’s Hospital of Philadelphia Researchers Unveil Key Mechanism in Immune System’s Fight Against Disease
Researchers at Children’s Hospital of Philadelphia (CHOP) and the Perelman School of Medicine at the University of Pennsylvania unlocked important new insights in how the immune system selects the right signals to alert T cells, a vital step in the prevention and treatment of serious illness. The findings were published in the journal Proceedings of the National Academy of Sciences (PNAS).
Vaccine News & Notes — January 2025
A report estimates that vaccines were directly responsible for a 40% decrease in infant deaths over the last 50 years. Find out more. You'll also learn about the rates of long COVID and about antibiotic-resistant bacteria in Ukraine.
Dr. Handy’s Corner: Can Adults Get a Booster Dose of Polio Vaccine If They’re Unsure about Their Immunity?
Watch as Dr. Handy discusses which adults might benefit from an additional dose of polio vaccine.
Feature Article: Getting Accurate Information in an Age of Misinformation
Unsure where to go to for trusted information about vaccines? Check out our list of resources. You'll also learn about why more information and access means more care when consuming that information.
Children’s Hospital of Philadelphia Researchers Develop New Tool with Potential to Advance Precision Medicine Treatment for Cancer
Researchers at Children’s Hospital of Philadelphia (CHOP) and the Perelman School of Medicine at the University of Pennsylvania developed a new screening technology, Aptamer-based T Lymphocyte Activity Screening and SEQuencing (ATLAS-seq), to better identify antigen-reactive T cells that are more likely to offer greater immune responses against cancer cells.
Q-and-A with a Trailblazer: N. Scott Adzick, MD
In this piece, Dr. Adzick reflects on the impact the center he helped establish 30 years ago has had on the field and on families.
First of Its Kind Gene Therapy Model Offers Hope for X-Linked Sideroblastic Anemia Treatment
Researchers at Children’s Hospital of Philadelphia (CHOP) and the University of Pennsylvania Perelman School of Medicine pioneered a first of its kind gene therapy model that offers a potential breakthrough in treating X-linked sideroblastic anemia (XLSA), a rare congenital anemia caused by mutations in the ALAS2 gene crucial for the synthesis of heme, a key compound in hemoglobin. This study marks the first time researchers studied gene therapy to treat this disease, which the authors underscore could have an impact on a broad spectrum of diseases. The research was published today and featured on the cover of the journal Blood.
Dr. Handy’s Corner: Why Do We See Measles Outbreaks?
Dr. Lori Handy discusses why measles outbreaks occur and what can be done to prevent them.
Feature Article — Parents PACK 2024: The Year in Review
See how well you do answering questions about information shared in 2024 Parents PACK newsletter articles.
Vaccine News & Notes — December 2024
Find info about: VMP's essay contest for students, VEC's new YouTube channel and video series, a new critical thinking resource, and when politicization of science results in lack of access to healthcare resources.