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Insights from the Gut Cell Atlas Convening 2024
The 2024 Gut Cell Atlas (GCA) Convening highlighted the most recent research advances into understanding the biology of Crohn’s disease. Drs. Kate Hamilton and Tatiana Karakasheva represent the Children’s Hospital of Philadelphia Research Institute in this initiative, which aims to build a detailed catalog the cell types composing human small and large intestines, further our understanding of Crohn's disease, and identify pathways towards curative therapy and ultimately, prevention.
2024 Research Annual Report, Did You Know: With Kathryn Hamilton, PhD, and Amanda Muir, MD
Doctors Amanda Muir and Kate Hamilton share a common interest in using patient-derived organoids to study pediatric gastrointestinal (GI) diseases. In 2019, they established the Gastrointestinal Epithelium Modeling Program, a collaborative effort dedicated to accelerating discovery and innovation in the search for cures and prevention strategies for these diseases.

Children’s Hospital of Philadelphia Raises More Than $745,000 for Rare Disease Research at Cheers for CHOP
On Saturday, February 22, 2025, Children's Hospital of Philadelphia (CHOP) hosted Cheers for CHOP, presented by Calvin Schmidt and family, at The Fillmore. The event benefitted rare disease research at CHOP, where rare cases are not so uncommon. Every dollar of the $745,000 (and counting!) raised will help our teams continue their work of translating rare disease research into more precise and personalized care for patients with some of the most complex medical cases.
Children’s Hospital of Philadelphia Researchers Characterize Spectrum of Causes and Symptoms of Mitochondrial DNA Deletion Rare Diseases
New techniques were utilized to recreate the goals of a natural history study of rare diseases in a fraction of the time.
Vaccine Resources: AI in Public Health Webinar and Laminated Vaccine Schedules
Check out a webinar on how to use AI in public health and where to order laminated vaccine schedules.
On the Bookshelf: "Just the Good Stuff" by Jim VandeHei
Find out about "Just the Good Stuff," a quick read from Jim VandeHei. In the book, he shares broadly applicable lessons from his career at the intersection of politics and journalism.
In the Journals: The Growing Trend of Deceitful, So-called “Journals”
Read about a paper that addressed the growing trend of disseminating fraudulent health information in purportedly “scientific journals.”
News & Views — Measles: Fast Facts for Healthcare Providers
Find key facts about symptoms of measles, how to diagnose and treat it, and how to reduce spread.
Technically Speaking: "A Bundled, Practice-Based Intervention to Increase HPV Vaccination"
Find out about a study demonstrating the value of an intervention bundle to improve HPV vaccination rates.
Children’s Hospital of Philadelphia Researchers Find That Both Neurotypical and Autistic Girls Smile More
Study adds to evidence on the importance of accounting for the impact of sex and gender differences on social impressions of autistic youth.