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Empowering Safety, One Gun Lock at a Time
From the ED to primary care offices, a CHOP program aims to reduce gun violence by distributing free gun locks and discussing safety.

Image-Based Precision Medicine
CHOP’s Cardiac Center harnesses new technologies, such as virtual reality, to deliver individualized, patient-specific care.

When a Kid Has an Emergency, They’ll Be Ready
Many emergency department doctors and nurses deal primarily with adult patients. A CHOP program prepares them for when a child comes through their doors.
Children’s Hospital of Philadelphia Preclinical Study Demonstrates Improved Gene Therapy Approach to Treating Metachromatic Leukodystrophy
In a preclinical study, researchers at Children’s Hospital of Philadelphia (CHOP) demonstrated a novel gene therapy with potentially increased effectiveness and safety for the treatment for metachromatic leukodystrophy (MLD), a rare disease in young children characterized by the deficient activity of a critical enzyme. Without effective treatment, MLD leads to rapidly declining neurological skills in young children and is potentially fatal. The promising findings were published in the journal Molecular Therapy Nucleic Acids.
Children’s Hospital of Philadelphia Cancer Researchers Elected to the 2025 Class of Fellows of the AACR Academy
Children’s Hospital of Philadelphia (CHOP) is honored to announce that distinguished cancer researchers Garrett M. Brodeur, MD, and Stephan A. Grupp, MD, PhD, have been elected to the 2025 class of Fellows of the American Association for Cancer Research (AACR) Academy.
Children’s Hospital of Philadelphia Researchers Use a “Trojan Horse” Approach to Develop New Antimalarial Drugs
Understanding how the parasites operate gives important insight into drug development for needed novel therapies
Solution for Rare and Complex Early-Onset Kidney Stones
This clinical case study describes a patient with early onset cystinuria, a rare genetic cause of kidney stones, that was first managed by multiple unsuccessful procedures and surgeries before referral to Children’s Hospital of Philadelphia.
Feature Article: 4 Vaccine Considerations for Those with Chronic Medical Conditions, Including Disabilities
Find four considerations that can help those who have chronic or disabling medical conditions navigate vaccine decisions.
Vaccine News & Notes — March 2025
Find info about the latest cases of measles and a video by Dr. Paul Offit providing a generational perspective on vaccines.

Improving Hypospadias Care Delivery through a CORES Research Grant
Christopher J. Long, MD, and his team utilized a Center for Outcomes Research in Surgery (CORES) grant to make considerable improvements to hypospadias care at CHOP.