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Research Studies Finder

Research Studies Finder

Use this finder to find a study or trial that is the right fit for your child. Also, filter results by phase — which are the specific steps researchers take throughout the trial to find answers, solutions and cures.

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Showing 1 - 10 of 186 results

Mitochondrial Myopathy Rating Scale

The purpose of this research study is to 1) validate the use of surveys such as fatigue scales, Mitochondrial Disease scales, and quality of life scales, 2) validate clinical exams, such as muscle strength tests, and the 6 minute walk test, and 3) to define the natural history of the disease in the Mitochondrial Disease patient population.

Phase: N/A

Actively recruiting: No

Category: Adults, Children, MRI/Imaging Studies

Food Genetics Behavior Study (FOODIE)

The University of Pennsylvania, in collaboration with CHOP, is conducting a study to find out more about how behaviors (eating, physical activity, sleep) and genes affect growth and development in children. Participants will include children, ages 5 to 7, and their mothers.Families will be asked to participate in a screening visit and 3 study visits over 1 year. Child participants will be asked to:

  • Eat dinner in our Center (visit 1);
  • Have their physical activity and sleep assessed over 14 days with a wrist-work activity monitor;
  • Have a saliva sample collected (visit 2), and
  • Have body measurements taken (visits 2 and 3).
Mothers will be asked to complete questionnaires throughout the study. Participants will be compensated for their time.

Phase: N/A

Actively recruiting: Yes

Category: Adults, Children, Healthy Controls

CrCEST MRI in Mitochondrial Disease

The Mitochondrial Medicine Program at the Childrens Hospital of Philadelphia is conducting a study focusing on non-invasive MRI procedures to measure biological activity within leg muscles of individuals, including both healthy volunteers and those with mitochondrial disease. This type of MRI is for research only, and it is not currently approved by the FDA. There is no direct benefit, but this research may contribute to future mitochondrial medicine. Your participation will last for approximately half a day during a visit at CHOP. We hope this research will contribute to the current knowledge of mitochondrial disease and improve diagnostic approaches. To learn more or inquire about this research study, please contact Sara Nguyen (nguyens2@chop.edu)

Phase: N/A

Actively recruiting: Yes

Category: Adults, Children, Healthy Controls, MRI/Imaging Studies, One-Time Visit Studies

MEG Biomarkers in Autistic Adults

This study is being done to understand how the brain of autistic adolescents and adults process sound and language. We hope the information gained from this study may lead to future therapies for language difficulties in autistic individuals.

Phase: N/A

Actively recruiting: Yes

Category: Adults, Children, Healthy Controls, MRI/Imaging Studies

Designing the ThyTSQ for Teens and Parents

This study aims to design and optimize the Hypothyroidism Treatment Satisfaction Questionnaire (ThyTSQ) for measuring treatment satisfaction among teenage patients on thyroid hormone supplementation and parents of children of any age treated for hypothyroidism.

Phase: N/A

Actively recruiting: Yes

Category: Adults, Children

FON

The goal of this research study is to transform outcomes for all people affected by single ventricle heart disease, particularly those with Fontan circulation. The Fontan Outcomes Network (FON) strives to advance our understanding of, and care for, single ventricle heart disease and address some of the major challenges. The ultimate goal is to dramatically improve physical health and functioning, neurodevelopment, and emotional health and resilience. To achieve that, we will collaborate between many care centers and with individuals with single ventricle heart disease and their families, to systematically collect information across the entire lifespan. FON includes a registry study, meaning information will be collected by your doctors and the researchers and entered and stored in a bank of information called a registry to be used for research as well as a learning network for quality improvement initiatives.

Phase: N/A

Actively recruiting: Yes

Category: Adults, Children

Managing Feeding and Sleep at Home

The goal of this research study is to learn more about how families manage mealtime and bedtime routines at home. We are enrolling primary caregivers (18+ years old) of children who are 4-10 years old that are on the autism spectrum or have Down Syndrome.

Participants will be compensated for their time. All participation is virtual.

Phase: N/A

Actively recruiting: No

Category: Adults, Remote (Online / Phone Call Only) Studies

17-SIBS study

The purpose of this research study is to understand the impact of transplant on the quality of life of the entire family including sibling donors, other siblings and parents.

Phase: N/A

Actively recruiting: Yes

Category: Adults, Children

Cancer Genomic Testing Study

The Department of Genomic Diagnostics is interested in studying genetic/molecular testing results from patients who are diagnosed with cancer as confirmed by genetic testing done at CHOP. In addition to studying genetic testing results, we also ask patients if we may access their clinical data that is collected and stored at CHOP (i.e., notes from provider visits, treatment information, lab results, etc.).

The purpose of collecting this data and test results is to learn how genetic and/or molecular testing impacts clinical care such as cancer diagnosis, treatment decisions, and outcomes. This data would additionally be provided to researchers (both inside and outside of CHOP) studying the molecular makeup of cancer and potential treatments. In these efforts, we hope to accelerate the process of cancer research and discovery by making this a widely available resource.

Phase: N/A

Actively recruiting: No

Category: Adults, Children

Sleep Questionnaire for Infants with or at high-risk of Cerebral Palsy

The purpose of this research study is to look at whether or not a sleep questionnaire can be used on infants 3 to 24 months of age, with or at high-risk of having Cerebral Palsy. This questionnaire is currently being used on older children, so we will be looking at a younger age group.

Phase: N/A

Actively recruiting: Yes

Category: Children, One-Time Visit Studies, Remote (Online / Phone Call Only) Studies

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