First Child to Receive Revolutionary CAR T Therapy Celebrates 10 Years Cancer Free
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Emily Whitehead, now 17, received life-saving treatment at CHOP, transforming the field of cancer immunotherapy.
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Emily Whitehead, now 17, received life-saving treatment at CHOP, transforming the field of cancer immunotherapy.
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More than 250 experts gathered in Philadelphia and virtually to discuss the latest scientific advancements and breakthroughs in pediatric precision medicine oncology.
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A new study in Nature has documented the longest persistence of CAR T cell therapy to date.
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Aberrant splicing leads to downregulation of CD22 in pediatric B-ALL, rendering malignant cells resistant to the effects of CD22-directed immunotherapies.
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A cell and gene therapy expert, Grupp discussed progress in clinical care in the 50 years since the legislation was signed.
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A collaborative team of researchers, including Dr. Stephan Grupp, recently presented preliminary data showing that a CRISPR-based gene-editing therapy for inherited blood disorders is safe and effective.
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The treatment modifies a domain in the CAR that targets CD19, making it look more human and therefore less likely to be rejected by patients.
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CHOP researchers were interviewed as a part of a comprehensive article about cell and gene therapy in Philadelphia Magazine.
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Dr. Shannon Maude, an attending physician in the Cancer Center at CHOP, provided expert insight on the unique challenges facing CAR T-cell therapy for pediatric indications in an article published in Healio’s February issue of Cell Therapy Next.
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