Department of Biomedical and Health Informatics (DBHi) News

The Department of Biomedical and Health Informatics (DBHi) is dedicated to advancing child health by developing innovative solutions that address healthcare's data and informatics needs.

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Researchers Identify RNA Editing Events that Impact Gene Expression and Phenotype

Mar 9, 2021

CHOP researchers have identified RNA editing events that influence gene expression and phenotype, showing that a single nucleotide change can have large downstream effects.

CHOP Researchers Characterize Shared Pathways in Epilepsy and Autism

Jan 19, 2021

In a new study, CHOP researchers integrate data regarding how the conditions present clinically with data on protein-protein interactions.

CHOP Researchers Find Mitochondrial Dysregulation Driving Spaceflight Health Risks

Nov 25, 2020

As part of a landmark package NASA papers, CHOP researchers have described significant mitochondrial changes due to spaceflight.

Study Involving Seven Major Children’s Hospitals Shows COVID-19 is Typically Mild in Children

Nov 23, 2020

Large, national study on COVID-19 in children led by CHOP found 4% of children tested were positive, but there were disparities in positivity rates and disease severity.

New Program Curbs Overuse of Prescriptions for Respiratory Illnesses, Study Finds

Aug 24, 2020

Researchers saw a 6% reduction in prescribing antibiotics that were likely unnecessary for pediatric patients when individual audits and communications strategies were put into place.

Pediatric Cell Atlas Will Map Single-cell Changes for a Deeper View of Child Health and Disease

Mar 28, 2019

Researchers plan to create a powerful new resource for fine-grained understanding of human growth and development, with an unprecedented window into the unique biology of children.

Researchers Use Data Tools to Rapidly Detect Sepsis in Sick Newborns

Mar 1, 2019

CHOP researchers used automated tools to identify sepsis in NICU babies hours before clinical recognition of the condition.

Automated Informatics Tool May Streamline Genetic Diagnoses

Jul 2, 2018

A CHOP bioinformatics scientist developed software that rapidly identifies information from electronic health records to help diagnose genetic diseases.

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