Lawrence Copelovitch, MD, is an attending physician in the Division of Nephrology, the Kidney Transplant and Dialysis Program, and the Pediatric Kidney Stone Center at Children's Hospital of Philadelphia.
Lawrence Copelovitch, MD, is an attending physician at Children's Hospital of Philadelphia and a Professor of Pediatrics at the Perelman School of Medicine at the University of Pennsylvania.
Dr. Copelovitch completed his undergraduate studies at McGill University in Montreal, Canada, where he graduated with First Class Honors and as a member of the Deans Honor List. He subsequently attended Albany Medical College where he was recognized with numerous awards, including the Daggett Prize in anatomies, the Arthur Knudson Prize in Biochemistry, the McGraw-Hill Award, and was nominated to the Alpha Omega Alpha Honorary Society in his junior year. He completed his pediatrics residency training at Rush University Medical Center in Chicago, where he was awarded the Pediatric Resident Teaching Award. He then joined the Children’s Hospital of Philadelphia as a pediatric nephrology fellow in 2004.
After completing his fellowship, he left for one year to volunteer as a pediatric nephrologist at the Angkor Hospital for Children in Siem Reap, Cambodia. Since returning to CHOP in 2008, he has primarily been a clinician. His primary areas of expertise include general nephrology, pediatric dialysis, hemolytic uremic syndrome, and kidney stones. In this role, he helped co-found the Pediatric Kidney Stone Center at CHOP in conjunction with Dr. Tasian in Urology. Together, they serve as the primary providers in this nationally recognized multidisciplinary specialty center. In 2012, he assumed the role of Medical Director of the Dialysis Unit, where his responsibilities include leading all clinical, regulatory and research initiatives for both the hemodialysis and peritoneal dialysis patient populations. In 2017, Dr. Copelovitch assumed the role of Medical Director of Supply Chain, where he is working to improve collaboration between clinicians and Supply Chain staff in order to best maximize hospital value analysis and improve efficiencies.
Education and Training
MD - Albany Medical College, Albany, NY
Pediatrics - Rush University Medical Center, Chicago, IL
Pediatrics - Rush University Medical Center, Chicago, IL
Pediatric Nephrology - The Children's Hospital of Philadelphia, Philadelphia, PA
Pediatric Nephrology – American Board of PediatricsPediatrics – American Board of Pediatrics
Titles and Academic Titles
Medical Director, Dialysis Unit
Medical Director, Supply Chain
Professor of Clinical Pediatrics, Perelman School of Medicine at the University of Pennsylvania
Onder AM, Flynn JT, Billings AA, Deng F, DeFreitas M, Katsoufis C, Grinsell MM, Patterson LT, Jetton J, Fathallah-Shaykh S, Ranch D, Aviles D, Copelovitch L, Ellis E, Chanda V, Elmaghrabi A, Lin JJ, Butani L, Haddad M, Couloures OM, Brakeman P, Quigley R, Stella SH, Garro R, Liu H, Rahimikollu J, Raina R, Langman CB, Wood EG. Predictors of patency for arteriovenous fistulae and grafts in pediatric hemodialysis patients. Pediatric Nephrology, Sep 2018. [Epub ahead of print]
Tasian GE, Jemielita T, Goldfarb DS, Copelovitch L, Gerber JS, Wu Q, Denburg MR. Oral Antibiotic Exposure and Kidney Stone Disease. J Am Soc Nephrol. 2018 May 10. pii: ASN.2017111213. doi: 10.1681/ASN.2017111213. [Epub ahead of print]
Kakajiwala A, Jemielita TO, Copelovitch L, Leonard MB, Furth SL, York A, Benton M, Hoofnagle AN, Windt K, Merrigan K, Lederman A, Denburg MR. Variability in measures of mineral metabolism in children on hemodialysis: impact on clinical decision-making. Pediatr Nephrol. 2017 Dec;32(12):2311-2318. doi: 10.1007/s00467-017-3730-4. Epub 2017 Jun 30.
Denburg MR, Leonard MB, Jemielita TO, Golden NH, Tasian G, Copelovitch L. Risk of Urolithiasis in Anorexia Nervosa: A Population-Based Cohort Study Using the Health Improvement Network. Eur Eat Disord Rev. 2017 Sep;25(5):406-410. doi: 10.1002/erv.2526. Epub 2017 Jun 29.
Tasian GE, Ross ME, Song L, Grundmeier RW, Massey J, Denburg MR, Copelovitch L, Warner S, Chi T, Killilea DW, Stoller ML, Furth SL. Dietary Zinc and Incident Calcium Kidney Stones in Adolescence. J Urol. 2017 May;197(5):1342-1348. doi: 10.1016/j.juro.2016.11.096. Epub 2016 Nov 23.
Wang X, Anglani F, Beara-Lasic L, Mehta AJ, Vaughan LE, Herrera Hernandez L, Cogal A, Scheinman SJ, Ariceta G, Isom R, Copelovitch L, Enders FT, Del Prete D, Vezzoli G, Paglialonga F, Harris PC, Lieske JC; Investigators of the Rare Kidney Stone Consortium. Glomerular Pathology in Dent Disease and Its Association with Kidney Function. Clin J Am Soc Nephrol. 2016 Dec 7;11(12):2168-2176. Epub 2016 Oct 3.
Tasian GE, Ross ME, Song L, Sas DJ, Keren R, Denburg MR, Chu DI, Copelovitch L, Saigal CS, Furth SL. Annual Incidence of Nephrolithiasis among Children and Adults in South Carolina from 1997 to 2012. Clin J Am Soc Nephrol. 2016 Mar 7;11(3):488-96. doi: 10.2215/CJN.07610715. Epub 2016 Jan 14.
Denburg MR, Jemielita TO, Tasian GE, Haynes K, Mucksavage P, Shults J, Copelovitch L. Assessing the risk of incident hypertension and chronic kidney disease after exposure to shock wave lithotripsy and ureteroscopy. Kidney Int. 2016 Jan;89(1):185-92. doi: 10.1038/ki.2015.321. Epub 2016 Jan 4.
Denburg MR, Jemielita TO, Tasian GE, Haynes K, Mucksavage P, Shults J, Copelovitch L. Assessing the risk of incident hypertension and chronic kidney disease after exposure to shockwave lithotripsy and ureteroscopy. Kidney Int. 2015 Oct 28. Epub ahead of print.
Clark SL, Taylor A, Shaw KN, Copelovitch L. Making every drop count for pediatric kidney transplant patients. Hosp Pediatr. 2015 May;5(5):287-9. doi: 10.1542/hpeds.2014-0146. No abstract available.
Denburg MR,Leonard MB,Haynes K,Tuchman S,Tasian G,Shults J, Copelovitch L. Risk of Fracture in Urolithiasis: A Population-Based Cohort Study using The Health Improvement Network. Clin J Am Soc Nephrol. 2014 Dec 5;9(12):2133-40.
Tasian GE, Copelovitch L. Evaluation and medical management of kidney stones in children. J Urol. 2014 Nov;192(5):1329-36. doi: 10.1016/j.juro.2014.04.108. Epub 2014 Jun 21. Review.
Ruebner RL, Copelovitch L, Evageliou NF, Denburg MR, Belasco JB, Kaplan BS. Nephrotic syndrome associated with tyrosine kinase inhibitors for pediatric malignancy: case series and review of the literature. Pediatr Nephrol. 2014 May;29(5):863-9. doi: 10.1007/s00467-013-2696-0. Epub 2013 Dec 7.
Kaplan BS, Ruebner RL, Spinale JM, Copelovitch L. Current treatment of atypical hemolytic uremic syndrome. Intractable Rare Dis Res. 2014 May;3(2):34-45.
Copelovitch L, Furth SL. Genetics and urinary tract malformations. Am J Kidney Dis. 2014 Feb;63(2):183-5. doi: 10.1053/j.ajkd.2013.11.005. Epub 2013 Dec 4. No abstract available.
Kaplan BS, Ruebner RL, Copelovitch L. Eculizumab treatment of atypical hemolytic uremic syndrome. Expert Opinion on Orphan Drugs 1(2): 167-176, 2013.
Copelovitch L, O'Brien MM, Guttenberg M, Otto EA, Kaplan BS: Renal-Hepatic-Pancreatic Dysplasia: A Sibship With Skeletal and Central Nervous System Anomalies and NPHP3 Mutation. Am J Med Genet A. 2013 Jul;161A(7):1743-9.
Spinale Joann M, Ruebner Rebecca L, Kaplan, Bernard S, Copelovitch, Lawrence. Update on Streptococcus pneumoniae associated hemolytic uremic syndrome. Curr Opin Pediatr. 2013 Apr;25(2):203-8.
Kakajiwala A, Rogers R, Pasch A, Copelovitch L, Hoofnagle A, Philipose S, Furth SL, Leonard MB, Denburg MR. Serum Calcification Propensity in Children on Chronic Hemodialysis. Pediatric Academic Societies Annual Meeting, 2019.
Vajravelu RK, Copelovitch L, Osterman MT, Scott FI, Mamtani R, Lewis JD, Denburg MR. Relative hazard of chronic kidney disease among patients with inflammatory bowel disease varies by age. Digestive Disease Week, 2019.
Denburg MR, Jemielita T, Goldfarb D, Wu Q, Copelovitch L, Gerber J, Tasian G: Association Between Oral Antibiotics and Incident Kidney Stones. Pediatric Academic Societies Annual Meeting 2017.
Nagata JM, Golden NH, Leonard MB, Copelovitch L, Denburg MR: Fracture Risk among Patients with Anorexia Nervosa: A Population-based Cohort Study using the Health Improvement Network. International Conference on Eating Disorders 2017.
Meyers ME and Copelovitch L: Going from the devil you know to the devil you don't: Transitioning ACT Monitors. A comparison of side-by-side monitoring in a heparinized pediatric Continuous Renal Replacement Therapy (CRRT) patient. 9th International pCRRT Conference on Pediatric Continuous Renal Replacement Therapy 2017.
Denburg MR, Jemielita T, Tasian G, Haynes K, Mucksavage P, Shults J, Copelovitch L: Urologic Interventions for Urolithiasis and Risk of Incident Hypertension and Chronic Kidney Disease: A Population-Based Cohort Study. ASN Kidney Week 2015 Annual Meeting 2015.
Clark SL, Taylor A, Shaw KN, Copelovitch L: Improving the Process of Tacrolimus Drug Monitoring: The Nephrology Experience. 2014 American Academy of Pediatrics (AAP) National Conference & Exhibition 2014
Copelovitch, L. Chapter 24: Acute Kidney Injury. The Kelalis--King--Belman Textbook of Clinical Pediatric Urology 6th Edition. CRC Press, Boca Raton, FL. 2018.
Bhatnagar S, Copelovitch L: Chapter 9: Fluids and Electrolytes. The Philadelphia Guide:Inpatient Pediatrics- 2nd Edition. McGraw Hill, Page: 121-130, 2015.
Beier UH, Copelovitch L. Congenital anomalies of the kidney and urologic system. In: Florin TA, Ludwig S, eds. Philadelphia: Elsevier; 2011. p. 408-413.
Awards and Honors
2022, Philadelphia Magazine's Top Doctors in Pediatric Nephrology
Editorial and Academic Positions
2011-present, Italian Journal of Pediatrics
2010-present, Clinical Journal of the American Society of Nephrology
2009-present, Journal of Pediatric Infectious Disease
2009-present, European Journal of Pediatrics
2011-present, American Society of Pediatric Nephrology (ASPN), Program Committee Member
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