Areas of Expertise:
Disordered mineral metabolism in chronic kidney disease, Nephrotic syndrome, Outcomes in chronic kidney disease, Translational research
MD - Weill Medical College of Cornell University, New York, NY
Pediatrics - Children’s Hospital of New York, New York, NY
Pediatric Nephrology - The Children's Hospital of Philadelphia, Philadelphia, PA
Pediatric Nephrology
MS in Clinical Epidemiology - University of Pennsylvania, Philadelphia, PA
Attending Physician
Assistant Professor of Pediatrics, Perelman School of Medicine at the University of Pennsylvania
Pilot and Feasibility Study: Vitamin D status in the Setting of Nephrotic Syndrome
Chronic Kidney Disease and Fracture Risk in Children, Adolescents and Young Adults: A Population-Based Study using The Health Improvement Network (THIN) Database
NEPTUNE
Chu David I, Pierce Christopher B, Tasian Gregory E, Denburg Michelle R, Ross Michelle E, Zderic Stephen A, Abraham Alison G, Furth Susan L. Urologic Care and Progression to End-Stage Kidney Disease: A Chronic Kidney Disease in Children (CKiD) Nested Case-Control Study. Journal of Pediatric Urology: doi: 10.1016, Mar 2019. epub ahead of print
Rhee Eugene P, Waikar Sushrut S, Rebholz Casey M, Zheng Zihe, Perichon Regis, Clish Clary B, Evans Anne M, Avila Julian, Denburg Michelle R, Anderson Amanda Hyre, Vasan Ramachandran S, Feldman Harold I, Kimmel Paul L, Coresh Josef. Variability of Two Metabolomic Platforms in CKD. Clinical journal of the American Society of Nephrology : CJASN 14(1): 40-48, Jan 2019.
Vajravelu Mary Ellen, Keren Ron, Weber David R, Verma Ritu, De León Diva D, Denburg Michelle R. Incidence and risk of celiac disease after type 1 diabetes: A population-based cohort study using the health improvement network database. Pediatric diabetes 19(8): 1422-1428, Dec 2018.
DeBoer Mark D, Lee Arthur M, Herbert Kirabo, Long Jin, Thayu Meena, Griffin Lindsay M, Baldassano Robert N, Denson Lee A, Zemel Babette S, Denburg Michelle R, Herskovitz Rita, Leonard Mary B: Increases in IGF-1 after Anti-TNF-α Therapy are Associated with Bone and Muscle Accrual in Pediatric Crohn's Disease. The Journal of clinical endocrinology and metabolism Jan 2018.
Tasian GE, Jemielita T, Goldfarb DS, Copelovitch L, Gerber JS, Wu Q, Denburg MR: Oral Antibiotic Exposure and Kidney Stone Disease. Journal of the American Society of Nephrology In press 2018.
Denburg Michelle, Nickolas Thomas L: Declining Hip Fracture Rates in Dialysis Patients: Is This Winning the War? American journal of kidney diseases : the official journal of the National Kidney Foundation 71(2): 154-156, Feb 2018.
Grewal S K, Wan J, Denburg M R, Shin D B, Takeshita J, Gelfand J M: The risk of IgA nephropathy and glomerular disease in patients with psoriasis: a population-based cohort study. The British journal of dermatology 176(5): 1366-1369, May 2017. PMCID: PMC5303688
Nagata Jason M, Golden Neville H, Leonard Mary B, Copelovitch Lawrence, Denburg Michelle R: Assessment of Sex Differences in Fracture Risk Among Patients With Anorexia Nervosa: A Population-Based Cohort Study Using The Health Improvement Network. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 32(5): 1082-1089, May 2017. PMCID: PMC5413380
Tasian Gregory E, Ross Michelle E, Song Lihai, Grundmeier Robert W, Massey James, Denburg Michelle R, Copelovitch Lawrence, Warner Steven, Chi Thomas, Killilea David W, Stoller Marshall L, Furth Susan L: Dietary Zinc and Incident Calcium Kidney Stones in Adolescence. The Journal of urology 197(5): 1342-1348, May 2017. PMCID: PMC5438256
Atkinson Meredith A, Leonard Mary B, Herskovitz Rita, Baldassano Robert N, Denburg Michelle R: Changes in Hepcidin and Hemoglobin After anti-TNF-alpha Therapy in Children and Adolescents with Crohn's Disease. Journal of pediatric gastroenterology and nutrition 66(1): doi: 10.1097, Jun 2017 Notes: Epub ahead of print. PMCID: PMC5723254
Horton Daniel B, Haynes Kevin, Denburg Michelle R, Thacker Mihir M, Rose Carlos D, Putt Mary E, Leonard Mary B, Strom Brian L: Oral glucocorticoid use and osteonecrosis in children and adults with chronic inflammatory diseases: a population-based cohort study. BMJ open 7(7): e016788, Jul 2017. PMCID: PMC5642748
Kakajiwala Aadil, Jemielita Thomas, Hughes John Z, Windt Kimberly, Denburg Michelle, Goldstein Stuart L, Laskin Benjamin: Membrane pressures predict clotting of pediatric continuous renal replacement therapy circuits. Pediatric nephrology (Berlin, Germany) 32(7): 1251-1261, Jul 2017. PMCID: PMC5441937
Sharma Sheena, Denburg Michelle R, Furth Susan L: The association between creatinine versus cystatin C-based eGFR and cardiovascular risk in children with chronic kidney disease using a modified PDAY risk score. Pediatric nephrology (Berlin, Germany) 32(8): 1457-63, Aug 2017.
Denburg Michelle R, Leonard Mary B, Jemielita Thomas O, Golden Neville H, Tasian Gregory, Copelovitch Lawrence: Risk of Urolithiasis in Anorexia Nervosa: A Population-Based Cohort Study Using the Health Improvement Network. European eating disorders review : the journal of the Eating Disorders Association 25(5): 406-410, Sep 2017.
Baker Joshua F, Long Jin, Mostoufi-Moab Sogol, Denburg Michele, Jorgenson Erik, Sharma Prerna, Zemel Babette S, Taratuta Elena, Ibrahim Said, Leonard Mary B: Muscle Deficits in Rheumatoid Arthritis Contribute to Inferior Cortical Bone Structure and Trabecular Bone Mineral Density. The Journal of rheumatology 44(12): 1777-1785, Dec 2017. PMCID: PMC5712255
Kakajiwala Aadil, Jemielita Thomas O, Copelovitch Lawrence, Leonard Mary B, Furth Susan L, York Amy, Benton Maryjane, Hoofnagle Andrew N, Windt Kimberly, Merrigan Karen, Lederman April, Denburg Michelle R: Variability in measures of mineral metabolism in children on hemodialysis: impact on clinical decision-making. Pediatric nephrology (Berlin, Germany) 32(12): 2311-2318, Dec 2017.
Isakova Tamara, Nickolas Thomas L, Denburg Michelle, Yarlagadda Sri, Weiner Daniel E, Gutiérrez Orlando M, Bansal Vinod, Rosas Sylvia E, Nigwekar Sagar, Yee Jerry, Kramer Holly: KDOQI US Commentary on the 2017 KDIGO Clinical Practice Guideline Update for the Diagnosis, Evaluation, Prevention, and Treatment of Chronic Kidney Disease-Mineral and Bone Disorder (CKD-MBD). American journal of kidney diseases : the official journal of the National Kidney Foundation 70(6): 737-751, Dec 2017.
Denburg Michelle R, Jemielita Thomas O, Tasian Gregory E, Haynes Kevin, Mucksavage Phillip, Shults Justine, Copelovitch Lawrence: Assessing the risk of incident hypertension and chronic kidney disease after exposure to shock wave lithotripsy and ureteroscopy. Kidney international 89(1): 185-92, Jan 2016. PMCID: PMC4911906
Denburg Michelle R, Kumar Juhi, Jemielita Thomas, Brooks Ellen R, Skversky Amy, Portale Anthony A, Salusky Isidro B, Warady Bradley A, Furth Susan L, Leonard Mary B: Fracture Burden and Risk Factors in Childhood CKD: Results from the CKiD Cohort Study. Journal of the American Society of Nephrology : JASN 27(2): 543-50, Feb 2016. PMCID: PMC4731126
Jemielita T O, Leonard M B, Baker J, Sayed S, Zemel B S, Shults J, Herskovitz R, Denburg M R: Association of 25-hydroxyvitamin D with areal and volumetric measures of bone mineral density and parathyroid hormone: impact of vitamin D-binding protein and its assays. Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA 27(2): 617-26, Feb 2016. PMCID: PMC4924926
Tasian Gregory E, Ross Michelle E, Song Lihai, Sas David J, Keren Ron, Denburg Michelle R, Chu David I, Copelovitch Lawrence, Saigal Christopher S, Furth Susan L: Annual Incidence of Nephrolithiasis among Children and Adults in South Carolina from 1997 to 2012. Clinical journal of the American Society of Nephrology : CJASN 11(3): 488-96, Mar 2016. PMCID: PMC4791823
DeBoer Mark D, Thayu Meena, Griffin Lindsay M, Baldassano Robert N, Denson Lee A, Zemel Babette S, Denburg Michelle R, Agard Hannah E, Herskovitz Rita, Long Jin, Leonard Mary B: Increases in Sex Hormones during Anti-Tumor Necrosis Factor α Therapy in Adolescents with Crohn's Disease. The Journal of pediatrics 171(1): 146-52, Apr 2016. PMCID: PMC4808610
Clark Stephanie L, Denburg Michelle R, Furth Susan L: Physical activity and screen time in adolescents in the chronic kidney disease in children (CKiD) cohort. Pediatric nephrology (Berlin, Germany) 31(5): 801-8, May 2016. PMCID: PMC4924924
Denburg Michelle R, Hoofnagle Andrew N, Sayed Samir, Gupta Jayanta, de Boer Ian H, Appel Lawrence J, Durazo-Arvizu Ramon, Whitehead Krista, Feldman Harold I, Leonard Mary B: Comparison of Two ELISA Methods and Mass Spectrometry for Measurement of Vitamin D-Binding Protein: Implications for the Assessment of Bioavailable Vitamin D Concentrations Across Genotypes. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 31(6): 1128-36, Jun 2016. PMCID: PMC4945118
Denburg Michelle R: Skeletal manifestations of renal disease in childhood. Current opinion in nephrology and hypertension 25(4): 292-300, Jul 2016.
Basiaga Matthew L, Burrows Evanette K, Denburg Michelle R, Meyers Kevin E, Grossman Andrew B, Mamula Petar, Grundmeier Robert W, Burnham Jon M: Variation in Preventive Care in Children Receiving Chronic Glucocorticoid Therapy. The Journal of pediatrics 179(1): 226-232, Dec 2016. PMCID: PMC5123921
Cohen Jordana B, Stephens-Shields Alisa J, Denburg Michelle R, Anderson Amanda H, Townsend Raymond R, Reese Peter P: Obesity, Renin-Angiotensin System Blockade and Risk of Adverse Renal Outcomes: A Population-Based Cohort Study. American journal of nephrology 43(6): 431-40, 2016. PMCID: PMC4955737
Chun Rene F, Liu Nancy Q, Lee T, Schall Joan I, Denburg Michelle R, Rutstein Richard M, Adams John S, Zemel Babette S, Stallings Virginia A, Hewison Martin: Vitamin D supplementation and antibacterial immune responses in adolescents and young adults with HIV/AIDS. The Journal of steroid biochemistry and molecular biology 148(1): 290-7, Apr 2015. PMCID: PMC4312738
Griffin Lindsay M, Thayu Meena, Baldassano Robert N, DeBoer Mark D, Zemel Babette S, Denburg Michelle R, Denson Lee A, Shults Justine, Herskovitz Rita, Long Jin, Leonard Mary B: Improvements in Bone Density and Structure during Anti-TNF-α Therapy in Pediatric Crohn's Disease. The Journal of clinical endocrinology and metabolism 100(7): 2630-9, Jul 2015. PMCID: PMC4490303
DeBoer Mark D, Weber David R, Zemel Babette S, Denburg Michelle R, Herskovitz Rita, Long Jin, Leonard Mary B: Bone Mineral Accrual Is Associated With Parathyroid Hormone and 1,25-Dihydroxyvitamin D Levels in Children and Adolescents. The Journal of clinical endocrinology and metabolism 100(10): 3814-21, Oct 2015. PMCID: PMC4596042
Freedberg D E, Haynes K, Denburg M R, Zemel B S, Leonard M B, Abrams J A, Yang Y-X: Use of proton pump inhibitors is associated with fractures in young adults: a population-based study. Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA 26(10): 2501-7, Oct 2015. PMCID: PMC4575851
Weber David R, Haynes Kevin, Leonard Mary B, Willi Steven M, Denburg Michelle R: Type 1 diabetes is associated with an increased risk of fracture across the life span: a population-based cohort study using The Health Improvement Network (THIN). Diabetes care 38(10): 1913-20, Oct 2015. PMCID: PMC4580610
Sharma S, Ehlayel AM, Copelovitch L. Chapter 50: Management of Fluids and Electrolytes. Nelson's Pediatric Board Review. Certification and Recertification. Elsevier, Philadelphia, PA. 2019.
Koepsell K, Denburg M, Lee JJ, Bittinger K, Tasian G. Decreased butyrate-production and oxalate-degradation of the gut microbiome in children and adolescents with calcium oxalate kidney stone disease. Oral presentation at the Societies for Pediatric Urology’s 67th Annual Meeting, Chicago, IL, May 2019.
Vajravelu RK, Copelovitch L, Osterman MT, Scott FI, Mamtani R, Lewis JD, Denburg MR. Relative hazard of chronic kidney disease among patients with inflammatory bowel disease varies by age. Poster presentation at Digestive Diseases Week, San Diego, CA, May 2019.
Koepsell K, Denburg M, Lee JJ, Bittinger K, Tasian G. Unique intestinal tract metabolites in calcium oxalate kidney stone disease. Oral presentation at the Societies for Pediatric Urology’s 67th Annual Meeting, Chicago, IL, May 2019.
Kakajiwala A, Rogers R, Pasch A, Copelovitch L, Hoofnagle A, Philipose S, Furth SL, Leonard MB, Denburg MR. Serum calcification propensity in children on chronic hemodialysis. Poster presentation at the Pediatric Academic Societies/American Society of Pediatric Nephrology Annual Meeting, Baltimore, MD, April 2019.
Greenberg J, Abraham A, Xu Y, Schelling J, Feldman H, Sabbisetti V, Cardenas-Gonzalez M, Coca S, Warady B, Kimmel P, Bonventre J, Denburg M, Parikh C, Furth S. Plasma biomarkers of chronic kidney disease progression in the CKiD Study. Poster presentation at the Pediatric Academic Societies/American Society of Pediatric Nephrology Annual Meeting, Baltimore, MD, April 2019.
Levy Erez D, Meyers M, Raman S, Thomas M, Forrest C, Furth S, Denburg M. The impact of pediatric peritoneal dialysis on caregivers’ self-reported health and well-being. Poster presentation at the Pediatric Academic Societies/American Society of Pediatric Nephrology Annual Meeting, Baltimore, MD, April 2019.
Thomas M, Raman S, Levy Erez D, Meyers MR, Furth S, Forrest CB, Denburg M. The impact of pediatric peritoneal dialysis on caregivers’ self-reported health and well-being. Oral presentation at the Eastern Society for Pediatric Research Scientific Meeting, Philadelphia, PA, March 2019.
Coresh J, Abraham AG, Denburg M, Furth S, Chen J, Rebholz C, Rhee E, Feldman H, Kimmel P, Ramachandran V, Warady B, Grams, M, Inker L, Levey AS. Concordance of metabolite correlations with measured GFR in children and adults. Poster presentation at the 51st Annual Meeting of the American Society of Nephrology, San Diego, CA, October 2018.
Brunson C, Huang L, Shults J, Furth SL, Denburg M, Hartung EA. Serum metabolomic biomarkers associated with neurocognitive dysfunction in youth with chronic kidney disease. Poster presentation at the 51st Annual Meeting of the American Society of Nephrology Meeting, San Diego, CA, October 2018.
Denburg, MR, Abraham AG, Coresh J, Chen J, Grams M, Feldman HI, Kimmel PL, Rebholz C, Rhee EP, Ramachandran VS, Warady BA, Furth SL. Metabolite predictors of chronic kidney disease progression in children. Poster presentation at the 51st Annual Meeting of the American Society of Nephrology, San Diego, CA, October 2018.
Sethna CB, Leonard MB, Meyers KE, Brady TM, Hoofnagle AN, Wolf M, Denburg M. FGF-23, hypertension, and dyslipidemia in glomerular disease. Poster presentation at the 51st Annual Meeting of the American Society of Nephrology, San Diego, CA, October 2018.