Suzanne P. MacFarland, MD

female silhouette icon
Suzanne P. MacFarland, MD, is an attending physician in the Division of Oncology and Cancer Predisposition Program at Children's Hospital of Philadelphia.

Areas of Expertise: Cancer predisposition, Juvenile polyposis syndrome, Peutz-Jeghers syndrome, Li-Fraumeni syndrome, PTEN hamartoma tumor syndrome, Familial adenomatous polyposis, Pediatric liver tumors
Locations: Main Hospital

Appointments and Referrals: 1-800-TRY-CHOP (1-800-879-2467)


Suzanne P. MacFarland, MD, is an attending physician in the Division of Oncology and a member of the Cancer Predisposition Program at Children's Hospital of Philadelphia (CHOP). She specializes in treating children with pediatric cancer predisposition syndromes including Li-Fraumeni Syndrome and pediatric polyposis syndromes such as Juvenile Polyposis Syndrome, Familial Adenomatous Polyposis, Peutz-Jeghers syndrome, and PTEN hamartoma tumor syndrome.  She is also a member of the Solid Tumor team, specializing in the diagnosis and management of pediatric solid tumors, with a focus on liver tumors. 

Her research is focused primarily on understanding the cause and improving the surveillance in these predisposition syndromes, particularly in pediatric polyposis syndromes and Li-Fraumeni syndrome.  She hopes that with improved methods of surveillance we can detect tumors at an earlier stage where treatment may be less intensive.  “Because they are at risk of further cancers down the line, we need to be thoughtful about their treatment and surveillance,” she says.

She chose to specialize in pediatric oncology out of a heartfelt desire to help children and families through some of life’s most challenging moments. She believes CHOP is particularly well-equipped to support children and their families, through many resources developed to treat each patient as an individual and to recognize their needs in the context of their family and community. “I hope every family leaves their first appointment at CHOP feeling like they have a team that is on their side,” she says. 

Dr. MacFarland earned her medical degree from the New York University School of Medicine in 2011. She completed her residency in Pediatrics as well as a fellowship in Pediatric Hematology/Oncology at CHOP in 2017.

She has won several awards for her work and patient care during her tenure at CHOP, including the Teddy Beddrossian Compassionate Care Award (2013), Senior Resident Humanitarian Award (2014) and the Pediatric Fellowship Teaching Award (2015). Dr. MacFarland also serves on the Hematology/Oncology Fellowship Committee and the Pediatric Intern Selection Committee.  She is also the co-founder of the Spirituality in Medicine discussion group. 

In addition to seeing patients she is also an assistant professor in the Division of Oncology, Department of Pediatrics at the University of Pennsylvania’s Perelman School of Medicine.

Currently, Dr. MacFarland’s research efforts are focused on pediatric polyposis syndromes and Li-Fraumeni syndrome. She says she is particularly interested in work that can improve methods of diagnosis as well as potential preventative measures for patients who are at risk of cancer.

Education and Training

Medical School

MD - New York University School of Medicine, New York, NY


Pediatrics - Children's Hospital of Philadelphia, Philadelphia, PA


Hematology/Oncology - Children's Hospital of Philadelphia, Philadelphia, PA

Board Certification

Pediatrics – American Board of Pediatrics

Titles and Academic Titles

Attending Physician

Instructor, Division of Oncology, Department of Pediatrics, Perelman School of Medicine at the University of Pennsylvania

Conditions Treated

Departments and Services




MacFarland S, Bauer AJ, Adzick NS, Surrey LF, Noyes J, Kazahaya K, Baloch Z, Mostoufi-Moab S: Disease burden and outcome in pediatric and young adults with concurrent Graves Disease and differentiated thyroid carcinoma. Journal of Clinical Endocrinology and Metabolism 103:2918-2925, 2018.


MacFarland SP, Mostoufi-Moab S, Zelley K, Mattei PA, States LJ, Bhatti TR, Duffy KA, Brodeur GM, Kalish JM. Management of adrenal masses in patients with Beckwith-Wiedemann syndrome. Management of adrenal masses in patients with Beckwith-Wiedemann syndrome. Pediatr Blood Cancer. 2017 Aug;64(8). doi: 10.1002/pbc.26432. Epub 2017 Jan 9.


Iyer R, Wehrmann L, Golden RL, Naraparaju K, Croucher JL, MacFarland SP, Guan P, Kolla V, Wei G, Cam N, Li G, Hornby Z, Brodeur GM. Entrectinib is a potent inhibitor of Trk-driven neuroblastomas in a xenograft mouse model. Cancer Letters. 2016; 372(2), 179-86. 


MacFarland SP, Hartung H. Pancytopenia in a patient with methylmalonic acidemia. Blood 2015; 125(11), 1840. 

Awards and Honors

2015, Pediatric Fellowship Teaching Award

2014, Senior Resident Humanitarian Award

2013, Teddy Beddrossian Compassionate Care Award

Editorial and Academic Positions

Academic and Institutional Committees

2016-present, Hematology/Oncology Fellowship Committee 

2016-present, Children’s Hospital of Philadelphia Fellows Association, Co-Chair

Leadership and Memberships

2015-present, American Society of Clinical Oncology

2015-present, American Association of Cancer Research

2015-present, Advances in Neuroblastoma Research

2014-present, Children’s Oncology Group