Suzanne P. MacFarland, MD
Areas of expertise: Cancer predisposition, Juvenile polyposis syndrome, Peutz-Jeghers syndrome, Li-Fraumeni syndrome, Familial adenomatous polyposis, Pediatric liver tumors, PTEN hamartoma tumor syndrome (PHTS)
Locations: Main Building
About Suzanne P. MacFarland, MD
Suzanne P. MacFarland, MD, is an attending physician in the Division of Oncology and the Director of the Cancer Predisposition Program at Children's Hospital of Philadelphia (CHOP). She specializes in treating children with pediatric cancer predisposition syndromes including Li-Fraumeni Syndrome and pediatric polyposis syndromes such as Juvenile Polyposis Syndrome, Familial Adenomatous Polyposis, Peutz-Jeghers syndrome, and PTEN hamartoma tumor syndrome. She is also a member of the Solid Tumor team, specializing in the diagnosis and management of pediatric solid tumors, with a focus on liver tumors.
Her research is focused primarily on understanding the cause and improving the surveillance in these predisposition syndromes, particularly in pediatric polyposis syndromes and Li-Fraumeni syndrome. She hopes that with improved methods of surveillance we can detect tumors at an earlier stage where treatment may be less intensive. “Because they are at risk of further cancers down the line, we need to be thoughtful about their treatment and surveillance,” she says.
She chose to specialize in pediatric oncology out of a heartfelt desire to help children and families through some of life’s most challenging moments. She believes CHOP is particularly well-equipped to support children and their families, through many resources developed to treat each patient as an individual and to recognize their needs in the context of their family and community. “I hope every family leaves their first appointment at CHOP feeling like they have a team that is on their side,” she says.
Dr. MacFarland earned her medical degree from the New York University School of Medicine in 2011. She completed her residency in Pediatrics as well as a fellowship in Pediatric Hematology/Oncology at CHOP in 2017.
She has won several awards for her work and patient care during her tenure at CHOP, including the Teddy Beddrossian Compassionate Care Award (2013), Senior Resident Humanitarian Award (2014) and the Pediatric Fellowship Teaching Award (2015). Dr. MacFarland also serves on the Hematology/Oncology Fellowship Committee and the Pediatric Intern Selection Committee. She is also the co-founder of the Spirituality in Medicine discussion group.
In addition to seeing patients she is also an assistant professor in the Division of Oncology, Department of Pediatrics at the University of Pennsylvania’s Perelman School of Medicine.
Currently, Dr. MacFarland’s research efforts are focused on pediatric polyposis syndromes and Li-Fraumeni syndrome. She says she is particularly interested in work that can improve methods of diagnosis as well as potential preventative measures for patients who are at risk of cancer.
Titles
Attending Physician
Director, Cancer Predisposition Program
Assistant Professor of Pediatrics, Perelman School of Medicine, University of Pennsylvania
Certifications
Pediatric Hematology-Oncology – American Board of Pediatrics
Awards and Honors
2024, Children’s Hospital of Philadelphia Heme/Onc Fellowship Teaching Award
2023, Children’s Hospital of Philadelphia Division of Oncology Educator Award
2020-2023, Pediatrics Residency Early Career Faculty Teaching Honor Roll
2015, Pediatric Residency Program Fellowship Teaching Award, Children's Hospital of Philadelphia
2014, Senior Resident Humanitarian Award, Children's Hospital of Philadelphia
Leadership and Memberships
2021-present, North American Society for Pediatric Gastroenterology, Hepatology, and Nutrition, Polyposis Special Interest Group (Steering Committee, 2022-)
2020-present, Collaborative Group of the Americas on Inherited Gastrointestinal Cancers
2020-present, Steering Committee, Consortium for Childhood Cancer Predisposition
2018-present, International Society for Gastrointestinal Hereditary Tumors
2018-present, Li-Fraumeni Syndrome Association
2016-present, American Association of Cancer Research
2016-present, American Society of Clinical Oncology
2016-present, American Society of Pediatric Hematology and Oncology (Cancer Predisposition SIG Vice Chair 2024-)
2011-present, American Academy of Pediatrics
Editorial and Academic Positions
Academic and Institutional Committees
2019-present, Children’s Hospital of Philadelphia Hematology/Oncology Fellowship Committee
2019-present, Children’s Hospital of Philadelphia Research Institute Responsible Conduct of Research Subcommittee
2016-present, Hematology/Oncology Fellowship Committee
2016-present, Children’s Hospital of Philadelphia Fellows Association, Co-Chair
Education & training
Undergraduate Degree
BA - Philosophy, Pennsylvania State University, State College, PA
BS - Biology, Pennsylvania State University, State College, PA
Graduate Degree
MS - Translational Research, University of Pennsylvania, Philadelphia, PA
Medical Degree
MD - New York University School of Medicine, New York, NY
Residency
Pediatrics - Children's Hospital of Philadelphia, Philadelphia, PA
Fellowship
Hematology/Oncology - Children's Hospital of Philadelphia, Philadelphia, PA
Publications
PubMed
Publications
2018
MacFarland S, Bauer AJ, Adzick NS, Surrey LF, Noyes J, Kazahaya K, Baloch Z, Mostoufi-Moab S: Disease burden and outcome in pediatric and young adults with concurrent Graves Disease and differentiated thyroid carcinoma. Journal of Clinical Endocrinology and Metabolism 103:2918-2925, 2018.
2017
MacFarland SP, Mostoufi-Moab S, Zelley K, Mattei PA, States LJ, Bhatti TR, Duffy KA, Brodeur GM, Kalish JM. Management of adrenal masses in patients with Beckwith-Wiedemann syndrome. Management of adrenal masses in patients with Beckwith-Wiedemann syndrome. Pediatr Blood Cancer. 2017 Aug;64(8). doi: 10.1002/pbc.26432. Epub 2017 Jan 9.
2016
Iyer R, Wehrmann L, Golden RL, Naraparaju K, Croucher JL, MacFarland SP, Guan P, Kolla V, Wei G, Cam N, Li G, Hornby Z, Brodeur GM. Entrectinib is a potent inhibitor of Trk-driven neuroblastomas in a xenograft mouse model. Cancer Letters. 2016; 372(2), 179-86.
2015
MacFarland SP, Hartung H. Pancytopenia in a patient with methylmalonic acidemia. Blood 2015; 125(11), 1840.