Elizabeth B. Rand, MD

Elizabeth B. Rand, MD

Elizabeth B. Rand, MD, is a pediatric gastroenterologist in the Division of Gastroenterology, Hepatology and Nutrition at Children's Hospital of Philadelphia. She is the Medical Director of CHOP's Liver Transplant Program and the Director of the Gastroenterology Fellowship Program.

Areas of Expertise: Liver transplant, Care for children after transplant, Acute liver failure, End-stage liver disease of any kind, Biliary atresia, Alagille syndrome, Autoimmune hepatitis, Secondary diseases of the liver
Locations: Main Campus
Phone: 1-877-ORGAN50

Background

Dr. Rand's interests are in the clinical care of children with liver disease, particularly Alagille syndrome, biliary atresia and liver transplantation. Research interests include clinical studies of biliary atresia and studies of immunization, immune suppression and long-term outcome after transplantation. Basic science interests in liver development and fibrosis are carried out as collaborations with FSBLC scientists who utilize the liver tissue bank.

Education and Training

Medical School

MD - University of Chicago, Pritzker School of Medicine, Chicago, IL

Internship

Pediatrics - Johns Hopkins Hospital, Baltimore, MD

Residency

Pediatrics - Johns Hopkins Hospital, Baltimore, MD

Fellowship

Pediatric Gastroenterology, Hepatology & Nutrition - University of Chicago, Chicago, IL

Additional Training

Research Fellow - Howard Hughes Medical Institute, University of Chicago, Chicago, IL

Board Certification

Pediatric Gastroenterology
Pediatric Transplant Hepatology
Pediatrics

Undergraduate Degree

AB in Chemistry - University of Chicago, Chicago, IL

Titles and Academic Titles

Medical Director, Liver Transplant Program

Director, Gastroenterology and Nutrition Fellowship Program

Associate Professor of Pediatrics, Perelman School of Medicine at the University of Pennsylvania

Conditions Treated

Departments and Services

Research Interests

Biliary development
Liver disease

Publications

Papers

2013

Schwartz Matthew C, Sullivan Lisa M, Glatz Andrew C, Rand Elizabeth, Russo Pierre, Goldberg David J, Rome Jonathan J, Cohen Meryl S: Portal and sinusoidal fibrosis are common on liver biopsy after Fontan surgery. Pediatric cardiology 34(1): 135-42, Jan 2013.

Squires Robert H, Dhawan Anil, Alonso Estella, Narkewicz Michael R, Shneider Benjamin L, Rodriguez-Baez Norberto, Olio Dominic Dell, Karpen Saul, Bucuvalas John, Lobritto Steven, Rand Elizabeth, Rosenthal Philip, Horslen Simon, Ng Vicky, Subbarao Girish, Kerkar Nanda, Rudnick David, Lopez M James, Schwarz Kathleen, Romero Rene, Elisofon Scott, Doo Edward, Robuck Patricia R, Lawlor Sharon, Belle Steven H: Intravenous N-acetylcysteine in pediatric patients with nonacetaminophen acute liver failure: a placebo-controlled clinical trial. Hepatology (Baltimore, Md.) 57(4): 1542-9, Apr 2013.

Mohammad S, Grimberg A, Rand E, Anand R, Yin W, Alonso EM: Long-Term Linear Growth and Puberty in Pediatric Liver Transplant Recipients. The Journal of Pediatrics 163(5): 1354-60, Nov 2013.

2012

Schwartz MC, Sullivan L, Cohen MS, Russo P, John AS, Guo R, Guttenberg Ma, Rand EB: Hepatic pathology may develop before the Fontan operation in children with functional single ventricle: an autopsy study. The Journal of Thoracic and Cardiovascular Surgery 143(4): 904-9, Apr 2012.

Kamath Binita M, Yin Wanrong, Miller Heather, Anand Ravinder, Rand Elizabeth B, Alonso Estella, Bucuvalas John: Outcomes of liver transplantation in alagille syndrome: The split experience. Liver Transplantation 18(8): 940-948, August 2012.

Cui R, Fayek SA, Rand EB, Feygin T, Khrichenko D, Shaked A: Central pontine myelinolysis: a case report and clinical-pathological review. Pediatric Transplantation 16(6): E251-6, Sept 2012.

Rychik J, Veldtman G, Rand E, Russo P, Rome JJ, Krok K, Goldberg DJ, Cahill AM, Wells RG: The Precarious State of the Liver After a Fontan Operation: Summary of a Multidisciplinary Symposium. Pediatr Cardiol 33(7): 1001-12, Oct 2012.

Akimova T, Kamath BM, Goebel J W, Meyers KEC, Rand EB, Hawkins A, Levine MH, Bucuvalas JC, Hancock WW: Differing effects of rapamycin or calcineurin inhibitor on T-regulatory cells in pediatric liver and kidney transplant recipients. American Journal of Transplantation 12(12): 3449-61, Dec 2012.

Goldberg DJ, Dodds K, Avitabile CM, Glatz AC, Brodsky JL, Semeao EJ, Rand EB, Mancilla EE, Rychik J: Children With Protein-Losing Enteropathy After the Fontan Operation Are at Risk for Abnormal Bone Mineral Density. Pediatric Cardiology 33(8), Dec 2012.

Ruebner R L, Reese P P, Denburg M R, Rand E B, Abt P L, Furth S L: Risk factors for end-stage kidney disease after pediatric liver transplantation. American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 12(12): 3398-405, Dec 2012.

Cárdenas Agustín M, Epelman Monica, Darge Kassa, Rand Elizabeth B, Anupindi Sudha A: Pre- and postoperative imaging of the Rex shunt in children: what radiologists should know. AJR. American journal of roentgenology 198(5): 1032-7, May 2012.

2011

Cui R, Fayek SA, Rand EB, Feygin T, Khrichenko D, Shaked A. Central pontine myelinolysis: a case report and clinical-pathological review. Pediatr Transplant.  Epub 2011 Oct 24. doi: 10.1111/j.1399-3046.2011.01591.x. Cited in PubMed; PMID 22023701. Read the abstract

Schwartz MC, Sullivan L, Cohen MS, Russo P, John AS, Guo R, et al. Hepatic pathology may develop before the Fontan operation in children with functional single ventricle: an autopsy study. J Thorac Cardiovasc Surg. Epub 2011 Sep 26. Cited in PubMed; PMID 21955477. Read the abstract

Mendizabal M, Reddy KR, Cassuto J, Olthoff KM, Faust TW, Makar GA, et al. Liver transplantation in patients with cystic fibrosis: analysis of United Network for Organ Sharing data. Liver Transpl. 2011 Mar; 17(3):243-50. doi: 10. 1002/lt22240. Cited in PubMed; PMID 21384506. Read the abstract

2010

Bunin N, Guzikowski V, Rand ER, Goldfarb S, Baluarte J, Meyers K, et al. Solid organ transplants following hematopoietic stem cell transplant in children. Pediatr Transplant. 2010 Dec;14(8):1030-5. doi: 10.1111/j.1399-3046.2010.01401.x. Epub 2010 Sep 15. Cited in PubMed; PMID 20846242. Read the abstract.

Leyva-Vega M, Gerfen J, Thiel BD, Jurkiewicz D, Rand EB, Pawlowska J, et al. Genomic alterations in biliary atresia suggest region of potential disease susceptibility in 2q37.3. Am J Med Genet A. 2010 Apr;152A(4):886-95. Cited in PubMed; PMID 20358598. Read the abstract

Kaye AJ, Rand EB, Munoz PS, Spinner NB, Flake AW, Kamath BM. Effect of Kasai procedure on hepatic outcome in Alagille syndrome. J Pediatr Gastroenterol Nutr. 2010 Jun 30. Cited in PubMed; PMID 20601899. Read the abstract

Leyva-Vega M, Gerfen J, Thiel BD, Jurkiewicz D, Rand EB, Pawlowska J, et al. Genomic alterations in biliary atresia suggest region of potential disease susceptibility in 2q37.3. Am J Med Genet A. 2010 Apr;152A(4):886-95. Cited in PubMed; PMID 20358598. Read the abstract

Abstracts

2012

Akimova T, Kamath B, Goebel J, Meyers EC, Rand EB, Bucuvalas JC, Hancock WW: Calcineurin inhibitor (CNI) use in pediatric liver and kidney transplant (Tx) patients is associated with increased risk of obesity and impaired T-regulatory (Treg) cell function American Association of Immunologists, Boston May 2012.

Hancock WW, Kamath B, Goebel J, Meyers KEC, Rand EB, Bucuvalas JC, Hawkins A, Akimova T: Differential effects of calcineurin inhibitor (CNI) versus rapamycin therapy on FOXP3 methylation and T regulatory (Treg) cell numbers, function, phenotype and viability in clinical pediatric liver and kidney allograft recipients American Transplant Congress, Boston June 2012.

Ruebner RL, Reese PP, Denburg MR, Rand EB, Abt PL, Furth SL: Risk factors for end stage kidney disease after pediatric liver transplantation. ATC oral presentation 2012; Young Investigator Award 2012.

Books

Chapters

2010

Kamath BM, Muir A, Rand EB: Nutritional Considerations in Pediatric Liver Transplant. Nutrition, Diet Therapy and the Liver. Preedy, Lakshman, Srirajaskanthan, and Watson (eds.). Taylor and Francis Group/CRC Press Publishers, Page: 307-319, 2010.

2008

Ryan MJ, Rand E: Primary Sclerosing Cholangitis. Pediatric Gastroenterology: The requisites in pediatrics. Liacouras and Piccoli (eds.). Mosby Elsevier Publishing, Page: 285-299, 2008.

2007

Kamath BM and Rand EB: Evaluation of the liver transplant candidate. Pediatric Solid Organ Transplantation. Fine, Ebber, Olthoff, Kelly and Harmon (eds.). Blackwell Publishing, Page: 207-212, 2007.

2006

Emerick Organ Transplant 16(5): 499-504, October 2011.M, Chrisant MA and Rand EB: Transplant Emergencies. Textbook of Pediatric Emergency Medicine. Fleisher, Ludwig & Henretig (eds.). Lippincott Williams & Wilkins, Page: 1727-1736, 2006.

2002

Rand EB and Olthoff KA: Pediatric Liver Transplantation. Liver Transplantation. Michael Lucey (eds.). 2002.

2001

Rand EB: Biliary Atresia, Obstructive Jaundice. Fetal and Neonatal Secrets, Hanely & Belfus. Polin (eds.). June 2001.

1998

Rand EB: Percutaneous Liver Biopsy. Clinical Pediatric Gastroenterology. Altschuler & Liacouras (eds.). Churchill Livingstone, London, 1998.

Rand EB: Alagille Syndrome. Clinical Pediatric Gastroenterology. Altschuler & Liacouras (eds.). Churchill Livingstone, London, 1998.

1990

Rand EB: Gastroenterology. Nutrition. The Harriet Lane Handbook, (12th Edition). Greene M (eds.). Year Book Medical Publishers Inc., Chicago, Page: 47-50 and 337-348, 1990.

 

 

Awards and Honors

2014,  Joanne Decker MD Mentor Award, Children's Hospital of Philadelphia
2013, GI Fellows Faculty Teaching Award
2012-2014, GI Fellows Faculty Honor Roll Awarded Annually 2012 and 2013
2007, Children's Hospital of Philadelphia, Master Clinician Award
2005, American Liver Foundation Physician of the Year Award
1998-2013, Pediatric Residents Faculty Honor Roll Awarded Annually
1996-2011, Invited to the Senior Dinner for graduating residents, Children's Hospital of Philadelphia, 1996, 1997, 2010, 2011
1994, Lawrence M. Gartner Fellowship Award for Excellence in Pediatric Research
1993, Postgraduate Biomedical Research Symposium, 1st Prize Basic Science Research Award, University of Chicago
1993-1994, MAPS Scholar, Molecular Approaches to Pediatric Science, The Joseph Stokes, Jr. Research Institute of The Children's Hospital of Philadelphia
1991-1993, Pediatric Scientist Development Award, The University of Chicago
1990-1991, Johnny Genna Fellowship Award, University of Chicago
1987, Richard Reilly Award for Outstanding Senior in Gastroenterology, University of Chicago

Editorial and Academic Positions

Editorial positions

2007-present, Section Editor, Hepatology; Pediatric Update
2006-present, Hospital Physician Pediatric Gastroenterology Board Review Manual
2000-present, Pediatric Transplantation, Reviewer
1998-present, Journal of Pediatric Gastroenterology and Nutrition, Reviewer

Academic committees

2009-present, Transplant Center Quality Assurance Committee
2009-present, Transplant Center Steering Committee
2000-present, Graduate Medical Education Committee

Leadership and Memberships

International

2011-present, International Pediatric Transplant Association (IPTA)

National

2003-present, American Society for Transplantation (AST)
2000-present, UNOS (CHOP Representative)
1993-present, North American Society for Pediatric Gastroenterology, Hepatology and Nutrition
1992-present, American Association for the Study of Liver Diseases (AASLD)