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Aberrant Splicing of CD22 in Acute Lymphoblastic Leukemia Underlies Resistance to Immunotherapy
Aberrant splicing leads to downregulation of CD22 in pediatric B-ALL, rendering malignant cells resistant to the effects of CD22-directed immunotherapies.
MyCHOP for Well and Sick Visits
Keeping your child healthy is a team effort. We’re here to help with well and sick visit appointments. Log in to MyCHOP to schedule an appointment at this location. Not a MyCHOP user? Request an access code by calling our office or requesting one at your next appointment, then sign up.
New Study Seeks to Preserve Kidney Function in Children with CKD
CHOP's Preserving Kidney Function in Children with Chronic Kidney Disease (PRESERVE) study was recently awarded funding from the Patient-Centered Outcomes Research Institute (PCORI). PRESERVE is a three-year, multi-institutional clinical trial evaluating blood pressure management and urine protein monitoring strategies to preserve kidney function in pediatric chronic kidney disease (CKD) patients.
CHOP Research Examines the History of Head Injuries in Classic Nursery Rhymes
From Humpty Dumpty to Jack and Jill, many classic fictional characters sustain their fair share of serious head injuries.
Rare Pair: HI and Kabuki Syndrome
Low blood sugar is one of the symptoms of Kabuki syndrome, a genetic disorder that affects multiple systems in the body but can be tricky to diagnose.
Coping with a Dual Diagnosis
Parents are usually blindsided when they find out that their child has congenital hyperinsulinism (HI), a rare genetic disorder that depresses blood sugar to dangerously low levels.
CHOP Researchers Find Possible Increased Tumor Risk in Some Patients with Beckwith-Wiedemann Spectrum
Researchers have unlocked patterns to improve the diagnosis of the most common epigenetic childhood cancer disorder.
CHOP Researchers Publish Most Comprehensive Clinical Description of WAGR Syndrome to Date
New research has identified several new clinical considerations and provides guidance for proper diagnosis and management of very rare disease.
Making Up for Lost Time: 13th Annual CHOP Global Health Conference
The CHOP Global Health Center, in collaboration with the Penn Center for Global Health, Penn Nursing, Temple University, and St. Christopher's Hospital for Children, hosted, "Making Up for Lost Time: Addressing Children's Needs Post-Pandemic." The conference brought together global child health experts in person for the first time in two years.
First Lady Dr. Jill Biden Visits CHOP
On Friday, December 3, 2021, First Lady Dr. Jill Biden visited our Nicholas and Athena Karabots Pediatric Care Center, where she met with families whose children had recently received the COVID-19 vaccine.