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CHOP-Led Animal Study Points to a Treatment for Huntington’s Disease
Researchers at The Children's Hospital of Philadelphia improved motor function and brain abnormalities in animals with a form of Huntington’s disease, a severe neurological disorder.
Fetal Myelomeningocele Repair: The Post-MOMS Experience
The CFDT Center at CHOP recently reviewed outcomes for fetal MMC repair since the MOMS results were reported, from referral and evaluation through surgery, delivery and neonatal discharge.
Fetal Myelomeningocele Closure: Technical Considerations
Fetal closure of an MMC is technically more challenging than the standard postnatal closure. The access is smaller, the structures are smaller and more delicate, the placode must be handled with more care, avoiding blood loss is critical, and the surgery must be performed quickly to limit the exposure of the fetus to the extrauterine environment.
Urologic Results After Fetal Myelomeningocele Repair in Pre-MOMS Patients
Before the start of the Management of Myelomeningocele Study (MOMS) in 2003, an initial group of 58 patients at CHOP underwent in utero repair of their myelomeningocele between 21 and 25 weeks' gestation. Urologic results after fMMC repair are discussed here.
The Role of Echocardiography in Intraoperative Management of Fetal MMC Repair
The Children's Hospital of Philadelphia has initiated a standard practice of continuous intraoperative echocardiographic monitoring for all fetuses undergoing myelomeningocele repair.
Tissue Engineering Strategies for Fetal MMC Repair
While the MOMS trial has demonstrated conclusively that open fetal surgery for repair of myelomeningocele improves outcomes, open fetal surgery for MMC is not a cure.
Diagnostic Imaging of Myelomeningocele
Myelomeningocele (MMC) poses a diagnostic and therapeutic challenge. A thorough and detailed examination of the entire fetus, with visualization of every spinal segment, is necessary.
S’mores and More
The Hole in the Wall Gang Camp, a nonprofit that helps kids with serious medical issues experience the joys of camp, sent 30 volunteers to The Children’s Hospital of Philadelphia last summer. They were armed with activity plans, supplies and an endless amount of energy and compassion.
Your Winter First-aid Kit: Getting It Together
When winter arrives, so do common winter illnesses. Here's how to stock your winter first-aid kit to be prepared.
CHOP Experts Draw Lessons from Philadelphia’s Large-Scale Obstetric Unit Closures
A new CHOP-led study finds that better planning is needed to improve mother-infant outcomes, and reduce stress on health systems and staff when hospital OB units close.