Case Study: Rotationplasty for Osteosarcoma
Jan 6, 2021
Van Nes rotationplasty surgery for osteosarcoma is a “functional amputation” in which the the foot is rotated 180 degrees on the vertical axis and the ankle becomes a functioning knee joint.
Cancer Center News
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Humanized CD19: CAR-T Immunotherapy for First Relapse of ALL in Down Syndrome Patient
Jan 11, 2019
An alternative, humanized CD19 CAR T product for first relapse of pediatric ALL is being evaluated in a clinical trial at Children's Hospital of Philadelphia.
Pediatric Brain Tumors: Advances in Low-grade Glioma Care and Research
Jan 10, 2019
Learn about CHOP's goal to develop improved, less toxic therapies for pediatric brain tumors by integrating neuro-oncology, neurosurgery, research and big data.
Proton Therapy for Craniopharyngioma
Jan 10, 2019
Proton therapy at CHOP helped Elena regain her vision and remain free of craniopharyngioma two years after treatment.
Children’s Hospital of Philadelphia Announces Endowed Chair in Pediatric Neuroblastoma Research
Sep 4, 2019
CHOP recipient, physician-scientist Dr. Yael Mossé, is innovating targeted, less toxic therapies for cancer affecting mostly infants and young children.
Remembering Dr. Giulio John D'Angio
Oct 30, 2018
Watch a memorial tribute to Dr. Giulio John D'Angio, pioneer in the treatment of children's cancers.
CHOP Scientists Report How Some Cancer Cells Develop Resistance to CAR T-cell Therapy
Nov 27, 2018
CHOP researchers analyze how some cancer cells resist a groundbreaking cellular therapy, and have found clues to overcoming that resistance.
Working to Improve Cure Rates for High-risk Neuroblastoma
Nov 16, 2018
Researchers at CHOP are working to discover the fundamental mechanisms that subvert normal neural development and orchestrate neuroblastoma tumorigenesis, and then to translate this knowledge into more effective and less toxic therapies.
CHOP Opens Manufacturing Facility, Making Tools for Disease Cures
Nov 1, 2018
The grand opening of CHOP’s new Clinical Manufacturing Facility highlights its role in manufacturing tools for 21st century precision medicine, to bring innovative treatments to patients.
Opening Door to Future Fertility for Survivors of Childhood Cancer
Oct 25, 2018
Two CHOP researchers were on a team that proposes potential ways to avoid future infertility in boys who are treated with chemotherapy and radiation for childhood cancer.