Pediatric Immunotherapy: What’s Next for CAR-T Therapy
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The FDA approval of Kymriah™ has shifted the paradigm for pediatric cancer treatment — and at Children's Hospital of Philadelphia, more cell therapies are on the horizon.
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The FDA approval of Kymriah™ has shifted the paradigm for pediatric cancer treatment — and at Children's Hospital of Philadelphia, more cell therapies are on the horizon.
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Researchers have found key differences among the most common types of pediatric brain tumors that may lead to more effective therapy.
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By identifying common gene variants that raise the risk of an aggressive form of the childhood cancer neuroblastoma, researchers may assist diagnostic efforts.
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This is a game changer for the treatment of pediatric patients battling leukemia and a pivotal milestone in this new era of cellular therapies that treat cancer with a patient’s own immune system.
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Since its inception in October 2016, the workshop has created recommendations for the 50 most common syndromes that predispose children to cancer and produced 16 position papers.
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Newly created videos allow families to see the facilities’ interiors and better understand what will happen during an outpatient visit before their scheduled appointment.
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The experimental, personalized cell therapy that amps up the patient's own immune system has passed a critical milestone in the path to full FDA approval.
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Five years after her T-cell therapy for ALL, Emily remains cancer-free. CHOP has since treated more than 170 patients in clinical trials that have seen a 93% remission rate.
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A DNA-cutting enzyme that regulates gene structure has a broad role in causing certain cancers. This discovery may eventually lead to more precise treatments.
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CHOP researchers reveal how mutations in a protein network drive several high-risk leukemias, offering prospects for new therapies.