N. Scott Adzick, MD, MMM, FACS, FAAP

N. Scott Adzick, MD, MMM, FACS, FAAP

N. Scott Adzick, MD, MMM, FACS, FAAP, is Surgeon-in-Chief of Children's Hospital of Philadelphia and the founder and Director of the Center for Fetal Diagnosis and Treatment.

Areas of Expertise: Fetal surgery, Clinical applications of fetal diagnosis and therapy, Endocrine surgery, Neonatal Surgery, Pectus surgery, Surgical treatment of hyperinsulinism, Thoracic Surgery, Thyroid and parathyroid surgery
Locations: Main Campus
Phone: 215-590-2730

Background

Dr. Adzick is the C. Everett Koop Professor of Pediatric Surgery at CHOP and the founder and Director of the Hospital’s Center for Fetal Diagnosis and Treatment. He also serves as CHOP’s Surgeon-in-Chief, Director of the Division of Pediatric General, Thoracic and Fetal Surgery, and Professor of Surgery, Obstetrics and Gynecology at the University of Pennsylvania School of Medicine.

A true innovator in the field of fetal medicine since its inception, Dr. Adzick has dedicated his career to the pursuit of groundbreaking prenatal treatment for debilitating birth defects. He has made pioneering contributions to the practice of fetal surgery, and today continues to explore cutting edge surgical treatment options for life-threatening fetal anatomic malformations such as urethral obstruction, congenital diaphragmatic hernia, congenital cystic adenomatoid malformation of the lung, and sacrococcygeal teratoma.

Dr. Adzick was the principal investigator for the National Institutes of Health (NIH) “Management of Myelomeningocele Study” (MOMS) at CHOP. This breakthrough study demonstrated that performing fetal surgery for spina bifida results in significantly improved outcomes versus conventional postnatal repair. The study represents the fruition of decades of research, much of it led by Dr. Adzick and his team, and is an example of how a once-radical idea can, through meticulous investigation, be transformed into a viable treatment for patients. Dr. Adzick is lead author of the study results, published in the New England Journal of Medicine.

“For the first time in the history of mankind, we have a new way to offer hope to families who have a diagnosis of spina bifida,” says Dr. Adzick. “It’s very gratifying to take an idea we had 20 years ago, test it thoroughly, apply it cautiously in the clinical setting and, eventually, have the ability to offer a new therapy that can completely change the life of a child.”

Dr. Adzick is also an active pediatric general and thoracic surgeon, and performs more than 400 operations a year. Much of his work is devoted to surgery in newborns including repairs for congenital diaphragmatic hernia, abdominal wall defects, lung lesions and other complex conditions affecting neonates.

In addition, Dr. Adzick has a special interest and expertise in surgery for Hyperinsulinism (HI) and pediatric thyroid disorders. Working closely with CHOP’s Congenital Hyperinsulinism Center, he has been instrumental in using 18 F-DOPA PET scanning technology to identify focal HI lesions in the pancreas, offering the chance of a complete surgical cure by performing partial pancreatectomy for affected patients. Dr. Adzick is also one of the nation’s most experienced surgeons in pediatric surgery to treat thyroid cancer and Graves disease, working in collaboration with CHOP’s Pediatric Thyroid Center.

Dr. Adzick earned his bachelor’s degree from Harvard College, his medical degree from Harvard Medical School, completed his surgical residency at Massachusetts General Hospital in Boston and his pediatric surgery fellowship at Boston Children’s Hospital. He holds a Masters of Medical Management degree from Carnegie Mellon University.

Dr. Adzick was a postdoctoral scholar at the University of California San Francisco, where he was an attending surgeon from 1988 until 1995, when he was recruited to The Children’s Hospital of Philadelphia as Surgeon-in-Chief.

Dr. Adzick has had NIH grant support for more than 30 years and has authored more than 500 peer-reviewed research papers. He was elected to the Institute of Medicine of the National Academy of Science in 1998. He is recognized worldwide for his contributions to the field of pediatric surgery, and for his creative leadership at CHOP to enhance the surgical care of children. 

In spring 2015, Dr. Adzick appeared in a three-part documentary series airing on PBS called TWICE BORN: Stories from the Special Delivery Unit. The Emmy® Award-winning documentary offered a look inside the Center for Fetal Diagnosis and Treatment at Children’s Hospital of Philadelphia, and its unique Garbose Family Special Delivery Unit.

To contact the Center for Fetal Diagnosis and Treatment, call 1-800-468-8376 (1-800-IN-UTERO).

Education and Training

Medical School

MD - Harvard Medical School, Boston, MA

Internship

Surgery - Massachusetts General Hospital, Boston, MA

Residency

Surgery - Massachusetts General Hospital, Boston, MA

Fellowship

Pediatric Surgery - Boston Children's Hospital, Boston, MA

Additional Training

Postdoctoral Scholar, Department of Surgery - University of California, San Francisco, CA

Board Certification

Pediatric Surgery
Surgery
Surgical critical care

Graduate Degree

Masters of Medical Management - Carnegie Mellon University, Pittsburgh, PA

Titles and Academic Titles

Surgeon-in-Chief, Department of Surgery

Chief, General, Thoracic and Fetal Surgery

Director, Center for Fetal Diagnosis and Treatment

C. Everett Koop Endowed Chair, Pediatric Surgery

Professor of Surgery, Obstetrics and Gynecology, Perelman School of Medicine at the University of Pennsylvania

Conditions Treated

Departments and Services

Publications

Papers

2018

Oliver ER, DeBari SE, Horii SC, Pogoriler JE, Victoria T, Khalek N, Howell LJ, Adzick NS, Coleman BG. Congenital Lobar Overinflation: A Rare Enigmatic Lung Lesion on PrenatalUltrasound and Magnetic Resonance Imaging.J Ultrasound Med. 2018 Sep 12. doi: 10.1002/jum.14801. [Epub ahead of print] Read the abstract.

Victoria T, Srinivasan AS, Pogoriler J, Kreiger PA, Laje P, Oliver ER, Danzer E, Johnson AM, Moldenhauer JS, Peranteau WH, Adzick NS. The rare solid fetal lung lesion with T2-hypointense components: prenatal imaging findings with postnatal pathological correlation. Pediatr Radiol. 2018 Jul 14; PMID: 30008034

Gibson CE, Boodhansingh KE, Li C, Conlin L, Chen P, Becker SA, Bhatti T, Bamba V, Adzick NS, De Leon DD, Ganguly A, Stanley CA. Congenital Hyperinsulinism in Infants with Turner Syndrome: Possible Association with Monosomy X and KDM6A Haploinsufficiency. Horm Res Paediatr. 2018 Jun 14; 1-10. [Epub ahead of print] PMID: 29902804

Riley JS, Antiel RM, Rintoul NE, Ades AM, Waqar LN, Lin N, Herkert LM, D'Agostino JA, Hoffman C, Peranteau WH, Flake AW, Adzick NS, Hedrick HL. Reduced oxygen concentration for the resuscitation of infants with congenital diaphragmatic hernia. J Perinatol. 2018 Jun 11. [Epub ahead of print]

Baumgarten HD, Gebb JS, Khalek N, Moldenhauer JS, Johnson MP, Peranteau WH, Hedrick HL, Adzick NS, Flake AW. Preemptive Delivery and Immediate Resection for Fetuses with High-Risk Sacrococcygeal Teratomas. Fetal Diagn Ther. 2018 May 7;:1-8. [Epub ahead of print] PMID: 29734172 

Victoria T, Andronikou S, Bowen D, Laje P, Weiss DA, Johnson AM, Peranteau WH, Canning DA, Adzick NS. Fetal anterior abdominal wall defects: prenatal imaging by magnetic resonance imaging. Pediatr Radiol. 2018 Apr;48(4):499-512. PMID: 29550866

Laje P, Fraga MV, Peranteau WH, Hedrick HL, Khalek N, Gebb JS, Moldenhauer JS, Johnson MP, Flake AW, Adzick NS. Complex gastroschisis: Clinical spectrum and neonatal outcomes at a referral center. J Pediatr Surg. 2018 Mar 14;. [Epub ahead of print] PMID: 29628208 

Adzick NS, De Leon DD, States LJ, Lord KL, Bhatti TR, Becker SA, Stanley CA.: Surgical Treatment of Congenital Hyperinsulinism: Results from 495 Pancreatectomies in Neonates and Children. American Pediatric Surgical Association March 2018 Notes: presentation March 12.

Farmer DL, Thom EA, Brock JW, Burrows PK, Johnson MP, Howell LJ, Farrell JA, Gupta N5, Adzick NS. Management of Myelomeningocele Study Investigators. The Management of Myelomeningocele Study: full cohort 30-month pediatric outcomes. Am J Obstet Gynecol. 2018 Feb;218(2): Epub 2017 Dec 12. PMID: 29246577

Swarr DT, Peranteau WH, Pogoriler J, Frank DB, Adzick NS, Hedrick HL, Morley M, Zhou S, Morrisey EE. Novel Molecular and Phenotypic Insights into Congenital Lung Malformations. Am J Respir Crit Care Med. 2018 Jan 12. doi: 10.1164/rccm.201706-1243OC. [Epub ahead of print] PubMed PMID: 29328793.

2017

Oliver ER, Coleman BG, DeBari SE, Victoria T, Looney DM, Horii SC, Moldenhauer JS, Langer JE, Howell LJ, Pawel BR, Adzick NS. Fetal Lymphatic Malformations: More Variable Than We Think? J Ultrasound Med. 2017 Jan 27. Doi:10.7863/ultra.16.04071. [Epub ahead of print]

Peranteau WH, Iyoob SD, Boelig MM, Khalek N, Moldenhauer JS, Johnson MP, Hedrick HL, Flake AW, Coleman BG, Adzick NS. Prenatal growth characteristics of lymphatic malformations. J Pediatr Surg. 2017 Jan;52(1):65-68.

Victoria T, Danzer E, Oliver ER, Edgar JC, DeBari SE, Partridge EA, Johnson AM, Peranteau WH, Coleman BG, Flake AW, Johnson MP, Hedrick H, Adzick NS. Right Congenital Diaphragmatic Hernias: Is There a Correlation between Prenatal Lung Volume and Postnatal Survival, as in Isolated Left Diaphragmatic Hernias? Fetal Diagn Ther. 2017 Mar 21. Doi:10.1159/000464246. [Epub ahead of print]

Oliver ER, DeBari SE, Giannone MM, Pogoriler JE, Johnson AM, Horii SC, Gebb JS, Howell LJ, Adzick NS, Coleman BG: Going with the Flow: An Aid in Differentiating Bronchopulmonary Sequestrations and Hybrid Lesions. J Ultrasound Med. 2017 Aug 10. doi: 10.1002/jum.14346. [Epub ahead of print].

Heuer GG, Moldenhauer JS, Adzick NS. Prenatal surgery for myelomeningocele: review of the literature and future directions. Childs Nerv Syst. 2017 Jul;33(7):1149-1155. Doi: 10.1007/s00381-017-3440-z. Epub 2017 May 17.

Kim AG, Danzer E, Moldenhauer JS, Khalek N, McClain LE, Waqar LN, Hedrick HL, Johnson MP, Adzick NS, Peranteau WH, Flake AW. Amniotic Fluid Concentrations of Glial Fibrillary Acidic Protein Do Not Correlate with Prenatal Metrics in Fetuses with Myelomeningocele. Fetal Diagn Ther. 2017 Jul 29. Doi: 10.1159/000478258. [Epub ahead of print].

Moldenhauer JS, Adzick NS. Fetal surgery for myelomeningocele: After the Management of Myelomeningocele Study (MOMS). Semin Fetal Neonatal Med. 2017 Oct 11. pii: S1744-165X(17)30093-8. doi: 10.1016/j.siny.2017.08.004. [Epub ahead of print]

2016

Unolt M, DiCairano L, Schlechtweg K, Barry J, Howell L, Kasperski S, Nance M, Adzick NS, Zackai EH, McDonald-McGinn DM. Congenital diaphragmatic hernia in 22q11.2 deletion syndrome. Am J Med Genet A. 2016 Sep 28. doi: 10.1002/ajmg.a.37980. Read abstract.

Danzer E, Hoffman C, D'Agostino JA, Gerdes M, Bernbaum J, Antiel RM, Rintoul NE, Herkert LM, Flake AW, Adzick NS, Hedrick HL. Neurodevelopmental outcomes at 5 years of age in congenital diaphragmatic hernia. J Pediatr Surg. 2016 Aug 30. pii: S0022-3468(16)30284-6. doi: 10.1016/j.jpedsurg.2016.08.008. Read abstract.

Antiel RM, Adzick NS, Thom EA, Burrows PK, Farmer DL, Brock JW 3rd, Howell LJ, Farrell JA, Houtrow AJ; Management of Myelomeningocele Study Investigators. Impact on family and parental stress of prenatal vs postnatal repair of myelomeningocele. Am J Obstet Gynecol. 2016 Jun 2. pii: S0002-9378(16)30264-2. doi: 10.1016/j.ajog.2016.05.045. Read abstract.

Johnson MP, Bennett KA, Rand L, Burrows PK, Thom EA, Thom LJ, Farrell JA, Dabrowiak ME, Brock JW 3rd, Farmer DL, Adzick NS, Management of Myelomeningocele Study Investigators. The Management of Myelomeningocele Study: obstetrical outcomes and risk factors for obstetrical complications following prenatal surgery. Am J Obstet Gynecol. 2016 Aug 2. pii: S0002-9378(16)30526-9. doi: 10.1016/j.ajog.2016.07.052. Read abstract.

Rychik J, Khalek N, Gaynor JW, Johnson MP, Adzick NS, Flake AW, Hedrick HL. Fetal Intrapericardial Teratoma: Natural History and Management Including Successful In Utero Surgery. Am J Obstet Gynecol. 2016 Aug 13. pii: S0002-9378(16)30575-0. doi: 10.1016/j.ajog.2016.08.010. Read abstract.

Lin EE, Moldenhauer JS, Tran KM, Cohen DE, Adzick NS. Anesthetic Management of 65 Cases of Ex Utero Intrapartum Therapy: A 13-Year Single-Center Experience. Anesth Analg. 2016 Aug;123(2):411-7. doi: 10.1213/ANE.0000000000001385. Read abstract.

Soni S, Moldenhauer JS, Spinner SS, Rendon N, Khalek N, Martinez-Poyer J, Johnson MP, Adzick NS: Chorioamniotic membrane separation and preterm premature rupture of membranes complicating in utero myelomeningocele repair. Am J Obstet Gynecol. 2016 May;214(5):647.e1-7. doi: 10.1016/j.ajog.2015.12.003. Epub 2015 Dec 12. Read the abstract

Peranteau WH, Adzick NS: Prenatal surgery for myelomeningocele. Curr Opin Obstet Gynecol. 2016 Apr;28(2):111-8. doi: 10.1097/GCO.0000000000000253. Read the abstract.

Coughlin CC, Roy SM, Arkin LM, MD, Adzick NS, Yan AC, De León DD, Rubin AI: Iatrogenic necrolytic migratory erythema in an infant receiving glucagon therapy for congenital hyperinsulinism. Pediatr Dermatol. 2016 Mar;33(2):e43-e47. doi: 10.1111/pde.12741. Epub 2015 Dec 9. Read the abstract.

Laje P, Hedrick HL, Flake AW, Adzick NS, Peranteau WH: Delayed abdominal closure after congenital diaphragmatic hernia repair.  J Pediatr Surg. 2016 Feb;51(2):240-3. doi: 10.1016/j.jpedsurg.2015.10.069. Epub 2015 Nov 11. Read the abstract.

Danzer E, Thomas NH, Thomas A, Friedman KB, Gerdes M, Koh J, Adzick NS, Johnson MP: Long-term neurofunctional outcome, executive functioning, and behavioral adaptive skills following fetal myelomeningocele surgery. Am J Obstet Gynecol. 2016 Feb;214(2):269.e1-8. doi: 10.1016/j.ajog.2015.09.094. Epub 2015 Oct 9. Read the abstract.

Bhatti TR, Ganapathy K, Huppman AR, Conlin L, Boodhansingh KE, MacMullen C, Becker S, Ernst LM, Adzick NS, Ruchelli ED, Ganguly A, Stanley CA: Histologic and molecular profile of pediatric insulinomas: Evidence of a paternal parent-of-origin effect. J Clin Endocrinol Metab. 2016 Mar;101(3):914-22. doi: 10.1210/jc.2015-2914. Epub 2016 Jan 12. Read the abstract.

Mancilla EE, Levine MA, Adzick NS: Outcomes of minimally invasive parathyroidectomy in pediatric patients with primary parathyroidism due to parathyroid adenoma: A single institution experience. J Pediatr Surg. 2016 Feb 4. pii: S0022-3468(16)00060-9. doi: 10.1016/j.jpedsurg.2016.01.018. [Epub ahead of print]. Read the abstract.

Hawkes CP, Adzick NS, Palladino AA, DeLeon DD: Late presentation of fulminant necrotizing enterocolitis in a child with hyperinsulinism on octreotide therapy. Horm Res Paediatr. 2016 Feb 12. [Epub ahead of print]. Read the abstract.

Danzer E, Gerdes M, D'Agostino JA, Bernbaum J, Hoffman C, Herkert LM, Rintoul NE, Peranteau WH, Flake AW, Adzick NS, Hedrick HL. Younger gestational age is associated with increased risk of adverse neurodevelopmental outcome during infancy in congenital diaphragmatic hernia. J Pediatr Surg. 2016 Jan 5. Read the abstract.

Peranteau WH, Boelig MM, Khalek N, Moldenhauer JS, Martinez-Poyer J, Hedrick HL, Flake AW, Johnson MP, Adzick NS: Effects of single and multiple courses of maternal betamethasone on prenatal congenital lung lesion growth and fetal survival. J Pediatr Surg. 2016 Jan;51(1):28-32. doi: 10.1016/j.jpedsurg.2015.10.018. Epub 2015 Oct 23. Read the abstract.

Kalish JM, Boodhansingh KE, Bhatti TR, Ganguly A, Conlin LK, Becker SA, Givler S, Mighion L, Palladino AA, Adzick NS, DeLeon DD, Stanley CA, Deardorff MA: Persistent congenital hyperinsulinism in children with mosaic paternal 11p uniparental isodisomy and variable features of Beckwith-Wiedemann Syndrome. J Med Genet. 2016 Jan;53(1):53-61. doi: 10.1136/jmedgenet-2015-103394. Epub 2015 Nov 6. Read the abstract.

2015

Tulipan NB, Wellons JC, Thom EA, Gupta N, Sutton LN, Burrows PK, Farmer DL, Johnson MP, Walsh W, Tolivaisa S, D’Alton ME, Adzick NS: Prenatal surgery for myelomeningocele and the need for ventricular shunt placement. J Neurosurg Pediatr. 2015 Dec;16(6):613-20. doi: 10.3171/2015.7.PEDS15336. Epub 2015 Sep 15.

Soni S, Moldenhauer JS, Spinner SS, Rendon N, Khalek N, Martinez-Poyer J, Johnson MP, Adzick NS. Chorioamniotic Membrane Separation and Preterm Premature Rupture of Membranes Complicating In Utero Myelomeningocele Repair. Am J Obstet Gynecol. 2015 Dec 12. Read the abstract.

Lord K, Radcliffe J, Gallagher PR, Adzick NS, Stanley CA, DeLeon DD: High risk of diabetes and neurobehavioral deficits in individuals with surgically treated hyperinsulinism. J Clin Endocrinol Metab. 2015 Nov;100(11):4133-9. doi: 10.1210/jc.2015-2539. Epub 2015 Sep 1. Read the abstract.

Laje P, Pearson EG, Simpao AF, Rehman MA, Sinclair T, Hedrick HL, Adzick NS, Flake AW. The first 100 infant thoracoscopic lobectomies: Observations through the learning curve and comparison to open lobectomy. J Pediatr Surg. 2015 Nov;50(11):1811-6. doi: 10.1016/j.jpedsurg.2015.05.015. Epub 2015 Jun 3. Read the abstract.

500. Olive A, Moldenhauer JS, Laje P, Johnson MP, Colemen BG, Victoria T, Flake A, Adzick NS: Axillary lymphatic malformations: Prenatal evaluation and postnatal outcomes. J Pediatr Surg. 2015 Oct;50(10):1711-5. doi: 10.1016/j.jpedsurg.2015.03.066. Epub 2015 Apr 29. Read the abstract.

Peranteau WH, Boelig MM, Khalek N, Moldenhauer JS, Martinez-Poyer J, Hedrick HL, Flake AW, Johnson MP, Adzick NS. Effect of single and multiple courses of maternal betamethasone on prenatal congenital lung lesion growth and fetal survival. J Pediatr Surg. 2015 Oct 23. Read the abstract.

Danzer E, Thomas NH, Thomas A, Friedman KB, Gerdes M, Koh J, Adzick NS, Johnson MP. Long-term neurofunctional outcome, executive functioning, and behavioral adaptive skills following fetal myelomeningocele surgery. Am J Obstet Gynecol. 2015 Oct 9. Read the abstract.

Partridge EA, Peranteau WH, Flake AW, Adzick NS, Flake AW: Frequency and complications of inguinal hernia repair in giant omphalocele. J Pediatr Surg. 2015 Oct;50(10):1673-5. doi: 10.1016/j.jpedsurg.2015.05.001. Epub 2015 May 29. Read the abstract.

Brock JW III, Carr MC, Adzick NS, Burrows PK, Thomas JC, Thom EA, Howell LJ, Farrell JA, Dabrowiak ME, Farmer DL, Cheng EY, Kropp BP, Caldamone AA, Bulas D, Tolivaisa S, Baskin LS: Bladder function after fetal surgery for myelomeningocele: Results of the MOMS Trial.  Pediatrics. 2015 Oct;136(4):e906-13. doi: 10.1542/peds.2015-2114. Read the abstract.

Tulipan N, Wellons JC 3rd, Thom EA, Gupta N, Sutton LN, Burrows PK, Farmer D, Walsh W, Johnson MP, Rand L, Tolivaisa S, D'alton ME, Adzick NS; for the MOMS Investigators. Prenatal surgery for myelomeningocele and the need for cerebrospinal fluid shunt placement. J Neurosurg Pediatr. 2015 Sep 15:1-8. [Epub ahead of print] Read the abstract.

Brock JW 3rd, Carr MC, Adzick NS, Burrows PK, Thomas JC, Thom EA, Howell LJ, Farrell JA, Dabrowiak ME, Farmer DL, Cheng EY, Kropp BP, Caldamone AA, Bulas DI, Tolivaisa S, Baskin LS; MOMS Investigators. Bladder Function After Fetal Surgery for Myelomeningocele. Pediatrics. 2015 Sep 28. pii: peds.2015-2114. [Epub ahead of print] Read the abstract

Heuer GG, Adzick NS, Sutton LN: Fetal myelomeningocele closure: Technical considerations. Fetal Diagn Ther. 2015;37(3):166-71. doi: 10.1159/000363182. Epub 2014 Aug 28. Read the abstract.

Moldenhauer JS, Soni S, Rintoul NE, Spinner SS, Khalek N, Martinez-Poyer J, Flake AW, Hedrick HL, Peranteau WH, Rendon N, Koh J, Howell LJ, Heuer GG, Sutton LN, Johnson MP, Adzick NS. Fetal Myelomeningocele Repair: The Post-MOMS Experience at the Children's Hospital of Philadelphia. Fetal Diagn Ther. 2015;37(3):235-40. Epub 2014 Aug 15. Read the abstract.

Rychik J, Cohen D, Tran K, Szwast A, Natarajan S, Johnson MP, Moldenhauer JS, Khalek N, Martinez-Poyer J, Flake AW, Hedrick HL, Adzick NS:  The role of echocardiography in the intraoperative management of the fetus undergoing myelomeningocele repair. Fetal Diagn Ther. 2015;37(3):172-8. doi: 10.1159/000364863. Epub 2014 Jul 18. Read the abstract.

Thawani JP, Nayak NR, Pisapia JM, Tahiri Y, Gebbia J, Adzick NS, Sutton LN, Taylor JA, Heuer GG: Myofascial closure of inclusion cysts following in utero myelomeningocele repair. Pediatr Neurosurg. 2015;50(5):286-90. doi: 10.1159/000433602. Epub 2015 Jul 14. Read the abstract.

Copp AJ, Adzick NS, Chitty LS, Fletcher JM, Holmbeck GN, Shaw GM: Spina Bifida. Nature Reviews Disease Primers 1: 20157, 2015.

Danzer E, Gerdes M, D'Agostino JA, Bernbaum J, Hoffman C, Herkert L, Rintoul NE, Peranteau WH, Flake AW, Adzick NS, Hedrick HL. Neurodevelopmental outcome at one year of age in congenital diaphragmatic hernia infants not treated with extracorporeal membrane oxygenation. J Pediatr Surg. 2015 Jun;50(6):898-903. doi: 10.1016. Read the abstract.

Partridge EA, Peranteau WH, Flake AW, Adzick NS, Hedrick HL. Frequency and complications of inguinal hernia repair in giant omphalocele. J Pediatr Surg. 2015 May 29. pii: S0022-3468(15)00353- PMID: 26078212. Read the abstract

Olive A, Moldenhauer JS, Laje P, Johnson MP, Coleman BG, Victoria T, Flake AW, Adzick NS. Axillary lymphatic malformations: Prenatal evaluation and postnatal outcomes. J Pediatr Surg. 2015 Apr 29. pii: S0022-3468(15)00312-7. doi: 10.1016. Read the abstract

Kovatch KJ, Isaacoff EJ, Prickett KK, Sullivan LM, Adzick NS, Kazahaya K, Bauer AJ, Mostoufi-Moab S: Incidence of pediatric thyroid carcinoma in patients with Graves’ Disease. Horm Res Paediatr. 2015 Apr 15. [Epub ahead of print]. Read the abstract.

Danzer E, Gerdes M, D’Agostino JA, Bernbaum J, Hoffman C, Rintoul NE, Herkert LM, Flake AW, Adzick NS, Hedrick HL: Patient characteristics are important determinants of short-term neurodevelopmental outcome in children with giant omphalocele. Early Hum Dev. 2015 Mar;91(3):187-93. doi: 10.1016/j.earlhumdev.2014.12.009. Epub 2015 Feb 9. Read the abstract.

Laje P, Peranteau WH, Hedrick HL, Flake AW, Johnson MP, Moldenhauer JS, Adzick NS. Ex utero intrapartum treatment (EXIT) in the management of cervical lymphatic malformation. J Pediatr Surg. 2015 Feb;50(2):311-4. doi: 10.1016/j.jpedsurg.2014.11.024. Epub 2014 Nov 10. Read the abstract.

Partridge EA, Victoria T, Coleman BG, Martinez-Poyer J, Laje P, Hedrick HL, Flake AW, Adzick NS. Prenatal diagnosis of esophageal bronchus - first report of a rare foregut malformation in utero. J Pediatr Surg. 2015 Feb;50(2):306-10. Epub 2014 Nov 10. Read the abstract.

Peranteau WH, Tharakan SJ, Partridge E, Herkert L, Rintoul NE, Flake AW, Adzick NS, Hedrick HL. Systemic hypertension in giant omphalocele: An underappreciated association. J Pediatr Surg. 2015 Feb 23. pii: S0022-3468(15)00131-1. doi: 10.1016. Read the abstract

Partridge EA, Hanna BD, Rintoul NE, Herkert L, Flake AW, Adzick NS, Hedrick HL, Peranteau WH. Brain-type natriuretic peptide levels correlate with pulmonary hypertension and requirement for extracorporeal membrane oxygenation in congenital diaphragmatic hernia. J Pediatr Surg. 2015 Feb;50(2):263-6. Read the abstract.

Peranteau WH, Scott Adzick N, Boelig MM, Alan W F, Hedrick HL, Howell LJ, Moldenhauer JS, Khalek N, Martinez-Poyer J, Johnson MP. Thoracoamniotic shunts for the management of fetal lung lesions and pleural effusions: a single-institution review and predictors of survival in 75 cases. J Pediatr Surg. 2015 Feb;50(2):301-5. Read the abstract.

Danzer E, Gerdes M, D'Agostino JA, Bernbaum J, Hoffman C, Rintoul NE, Herkert LM, Flake AW, Adzick NS, Hedrick HL. Patient characteristics are important determinants of neurodevelopmental outcome during infancy in giant omphalocele. Early Hum Dev. 2015 Feb 9;91(3):187-193. Read the abstract.

Partridge EA, Peranteau WH, Rintoul NE, Herkert LM, Flake AW, Adzick NS, Hedrick HL. Timing of repair of congenital diaphragmatic hernia in patients supported by extracorporeal membrane oxygenation (ECMO). J Pediatr Surg. 2015 Feb;50(2):260-2. Read the abstract.

2014

Partridge EA, Hanna B, Panitch HB, Rintoul NE, Peranteau WH, Flake AW, Adzick NS, Hedrick HL: Pulmonary hypertension in giant omphalocele infants. J Pediatr Surg. 2014 Dec;49(12):1767-70. doi: 10.1016/j.jpedsurg.2014.09.016. Epub 2014 Nov 14. Read the abstract.

Vrecenak JD, Howell LJ, Khalek N, Moldenhauer JS, Johnson MP, Coleman BG, Victoria T, Hedrick HL, Peranteau WH, Flake AW, Adzick NS: Outcomes of prenatally diagnosed chest masses in multigestational pregnancies. Fetal Diagn Ther. 2014;36(4):312-9. doi: 10.1159/000358325. Epub 2014 Nov 5. Read the abstract.

Partridge EA, Bridge C, Donaher JG, Herkert L, Grill E, Danzer E, Gerdes M, D’Agnostino JA, Peranteau, WH, Hoffman-Craven CH, Bernbaum JC, Rintoul NE, Flake AW, Adzick NS, Hedrick HL: Incidence and factors associated with sensorineural and conductive hearing loss among survivors of congenital diaphragmatic hernia. J Pediatr Surg. 2014 Jun;49(6):890-4; discussion 894. doi: 10.1016/j.jpedsurg.2014.01.019. Epub 2014 Jan 31. Read the abstract.

Bebbington MW, Victoria T, Danzer E, Moldenhauer JS, Khalek N, Johnson MP, Hedrick HL, Adzick NS: Comparison of Ultrasound and MRI parameters in predicting survival in isolated left-sided congenital diaphragmatic hernia. Ultrasound Obstet Gynecol. 2014 Jun;43(6):670-4. doi: 10.1002/uog.13271. Epub 2014 May 5. Read the abstract.

Jackson EM, Schwartz DM, Zarnow DA, Adzick NS, Johnson MP, Heuer GG, Sutton LN: Intraoperative neurophysiological monitoring in patients undergoing tethered cord surgery after fetal myelomeningocele repair. J Neurosurg Pediatr. 2014 Apr;13(4):355-61. doi: 10.3171/2014.1.PEDS11336. Epub 2014 Feb 7. Read the abstract.

Tsai J, Blinman TA, Collins JL, Laje P, Hedrick HL, Adzick NS, Flake AW: The contribution of hiatal hernia to gastroesophageal reflux disease in patients with gastroschisis. J Pediatr Surg. 2014 Mar;49(3):395-8. doi: 10.1016/j.jpedsurg.2013.09.005. Read the abstract.

Peranteau WH, Moldenhauer JS, Khalek N, Martinez-Poyer JL, Howell LJ, Johnson MP, Flake AW, Adzick NS, Hedrick HL: Open fetal surgery for central bronchial atresia. Fetal Diagn Ther. 2014;35(2):141-7. doi: 10.1159/000357497. Epub 2014 Jan 23. Read the abstract.

Partridge EA, Canning DA, Long C, Peranteau WP, Hedrick HL, Adzick NS, Flake AW: Urologic and anorectal complications of sacrococcygeal teratoma: Prenatal and postnatal predictors. J Pediatr Surg. 2014 Jan;49(1):139-42; discussion 142-3. doi: 10.1016/j.jpedsurg.2013.09.042. Epub 2013 Oct 8. Read the abstract.

2013

Laje P, Palladino AA, Bhatti TR, States LJ, Stanley CA, Adzick NS: Pancreatic surgery in Infants with Beckwith-Wiedemann Syndrome and Hyperinsulinism. J Pediatric Surg 48:2511-2516, 2013.

Peranteau WP, Palladino AA, Bhatti TR, States L, Stanley CA, Adzick NS: The surgical management of insulinomas in children. J Pediatr Surg 48:2517-2524, 2013.

Adzick NS: The tribulations and trials of fetal surgery for spina bifida. Proceedings of the American Philosophical Society 157:41-69, 2013.

Kaplan MC, Coleman BG, Shaylor SD, Howell LJ, Horii SC, Adzick NS: Sonographic features of rare posterior neck masses of vascular origin. J Ultrasound Med 32:873-880, 2013.

Danzer E, Gerdes M, D’Agostino JA, Partridge EA, Hoffman-Craven C, Bernbaum J, Rintoul NE, Flake AW, Adzick NS, Hedrick HL: Longitudinal neurodevelopmental and neuromotor outcome in congenital diaphragmatic hernia patients in the first 3 years of life. J Perinatology 33:893-898, 2013.

Laje P, Adzick NS: Modified Puestow for the management of chronic pancreatitis in children. J Pediatr Surg 48:2271-2275, 2013.

Laje P, Bhatti TR, Adzick NS: Solid pseudopapillary neoplasm of the pancreas in children: A 15 year experience and identification of a unique immunohistochemical marker. J Pediatr Surg 48:2054-2060, 2013.

Laje P, Howell LJ, Johnson MP, Hedrick HL, Flake AW, Adzick NS: Perinatal management of congenital oropharyngeal tumors: the Ex Utero Intrapartum Treatment (EXIT) approach. J Pediatr Surg 48:2005-2010, 2013.

Danzer E, Gerdes M, D’Agostino J, Partridge E, Hoffman-Craves C, Bernbaum J, Rintoul NE, Flake AW, Adzick NS, Hedrick HL: Preschool neurological assessment in congenital diaphragmatic hernia survivors: Outcome and perinatal factors associated with neurodevelopmental impairment. Early Human Development 89:393-400, 2013.

Adzick NS: Fetal surgery for spina bifida: Past, present, future. Sem Pediatric Surgery 22:10-17, 2013.

Adzick NS: Preface to Fetal Surgery – Current Status. Sem Pediatric Surgery 22:1-2, 2013.

Victoria T, Danzer E, Adzick NS: Use of ultrasound and MRI for evaluation of lung volumes in fetuses with isolated congenital diaphragmatic hernia. Sem Pediatric Surgery 22:30-36, 2013.

Laje P, States LJ, Zuang H, Becker SA, Palladino AA, Stanley CA, Adzick NS: The accuracy of PET/CT scan in the diagnosis of the focal form of congenital hyperinsulinism. J Pediatr Surg 48:388-393, 2013.

aje P, Palladino AA, Bhatti TR, States LJ, Stanley CA, Adzick NS: Pancreatic surgery in Infants with Beckwith-Wiedemann Syndrome and Hyperinsulinism. J Pediatric Surg 48:2511-2516, 2013.

2012

Danzer E, Hedrick HL, Rintoul NE, Adzick NS, Panitch HB: Comprehensive assessment of early pulmonary function abnormalities in giant omphalocele survivors. J Pediatr Surg 47:1811-20, 2012.

Victoria T, Bebbington MW, Danzer E, Flake AW, Johnson MP, Adzick NS, Hedrick HL: Use of magnetic resonance imaging in prenatal prognosis of the fetus with isolated left congenital diaphragmatic hernia. Prenatal Diagnosis 32: 715-723, 2012.

Danzer E, Siegle J, D’Agnostino JA, Gerdes M, Hoffman C, Bernbaum J, Rintoul NE, Flake AW, Adzick NS, Hedrick HL: Early neurodevelopmental outcome of infants with high-risk fetal lung lesions. Fetal Diagnosis and Therapy 31:210-215, 2012.

Tsai J, Sulkowski J, Adzick NS, Hedrick HL, Flake AW: Patch repair for congenital diaphragmatic hernia: Is there really a problem? J Pediatr Surg 47:637-641, 2012.

Adzick NS: Fetal myelomeningocele repair: Trials and tribulations. J Pediatr Surg 47:273-281, 2012.

Laje P, Johnson MP, Howell LJ, Bebbington MW, Hedrick HL, Flake AW, Adzick NS: Ex Utero Intrapartum Treatment (EXIT) in the management of giant cervical teratomas. J Pediatr Surg 47:1208-16, 2012.

Danzer E, Zarnow D, Gerdes M, D’Agostino JA, Siegle J, Bebbington MW, Flake AW, Adzick NS, Hedrick HL: Abnormal brain development and maturation on MR imaging in congenital diaphragmatic hernia survivors. J Pediatr Surg 47:453-461, 2012.

Danzer E, Victoria T, Bebbington MW, Siegle J, Rintoul NE, Johnson MP, Flake AW, Adzick NS, Hedrick HL: Fetal MRI calculated lung volumes in the prediction of short-term morbidity in giant omphalocele: Preliminary findings.  Fetal Diagnosis and Therapy 31:248-253, 2012.

Laje P, Stanley CA, Palladino AA, Becker SA, Adzick NS: Pancreatic head resection and Roux-en-Y pancreaticojejunostomy for the treatment of the focal form of congenital hyperinsulinism. J Pediatr Surg 47:130-135, 2012.

Danzer E, Johnson MP, Adzick NS: Fetal surgery for myelomeningocele: Progress and    perspectives. Dev Med Child Neurol Dev Med Child Neurol. 54:8-14, 2012.

2011

Danzer E, Gerdes M, Bebbington MW, Koh J, Adzick NS, Johnson MP: Preschool neurobehavioral outcome of following fetal myelomeningocele surgery.  Fetal Diagnosis and Therapy 30:174-179, 2011.

Danzer E, Adzick NS: Fetal surgery for myelomeningocele: Patient selection, perioperative management, and clinical studies. Fetal Diagnosis and Therapy 30:163-173, 2011.

Bebbington MW, Danzer E, Johnson MP, Adzick NS: Fetal surgery for myelomeningocele. Prenatal Diagnosis 31:689-694, 2011.

Santore MT, Behar BJ, Blinman TA, Adzick NS, Flake AW, Deans KJ: Laparoscopic hepaticoduodenostomy versus open hepatoduodenostomy for reconstruction after resection of choledochal cyst. Journal of Laparoendoscopic & Advanced Surgical Techniques 221:375-8, 2011.

Grant RA, Heuer GG, Carrion GM, Adzick NS, Schwartz ES, Stein SC, Storm PB, Sutton LN,: Morphometric analysis of posterior fossa after in utero myelomeningocele repair. Journal of Neurosurgery: Pediatrics 7:362-8, 2011.

Adzick NS, Thom EA, Spong CY, Brock JW III, Burrows PK, Johnson MP, Howell LJ, Farrell JA, Dabrowiak ME, Sutton LE, Gupta N, Tulipan NB, D’Alton ME, Farmer DL: A randomized trial of prenatal versus postnatal repair of myelomeningocele.  N Engl J Med 364:993-1004, 2011.

Danzer E, Gerdes M, Bebbington MW, Koh J, Adzick NS, Johnson MP: Fetal myelomeningocele surgery: Preschool functional status using the Functional Independence Measure for Children (WeeFIM). Child's Nervous System 27:1083-8, 2011.

Roybal JL, Moldenhauer JS, Khalek N, Bebbington MW, Johnson MP, Hedrick HL, Adzick NS, Flake AW: Early delivery as an alternative management strategy for selected high-risk sacrococcygeal teratomas. J Pediatr Surg 46:1325-32, 2011.

Danzer E, Zhang L, Radu A, Bebbington MW, Liechty KW, Adzick NS, Flake AW: Amniotic fluid levels of glial fibrillary acidic protein in fetal rats with retinoic acid induced myelomeningocele: A potential marker for spinal cord injury. Am J Ob Gyn 204:178.e1-11, 2011.

Santore MT, Behar BJ, Blinman TA, Doolin EJ, Hedrick HL, Mattei P, Nance ML, Adzick NS, Flake AW: Hepaticoduodenostomy versus hepaticojejunostomy for reconstruction after resection of choledochal cyst. J Pediatr Surg 46:209-213, 2011.

2010

Deprest JA, Flake AW, Gratacos E, Ville Y, Hecher K, Nicolaides K, Johnson MP, Adzick NS, Harrison MR: The making of fetal surgery. Prenatal Diagnosis 30:653-667, 2010.

Roybal JI, Liechty KW, Hedrick HL, Bebbington M, Johnson MP, Coleman B, Adzick NS, Flake AW: Predicting the severity of Congenital High Airway Obstruction Syndrome. J Pediatr Surg 45:1633-1639, 2010.

Danzer E, Finkel R, Gerdes M, Schwartz EM, Rintoul NN, Adzick NS, Johnson MP: The relationship of seizure activity and chronic epilepsy in early infancy and short-term neurodevelopmental outcome following fetal myelomeningocele closure. Neuropediatrics 41:140-143, 2010.

Danzer E, Layne MD, Auber F, Shigu S, Kreiger P, Radu A, Adzick NS, Flake AW: Gastroschisis in mice lacking aortic carboxypeptidase-like protein (ACLP) is associated with a defect in neuromuscular development restricted to the eviscerated intestine: Early characterization and histomorphological assessment. Pediatric Research 68:23-28, 2010.

Laje P, Flake AW, Adzick NS: Prenatal diagnosis and postnatal resection of intra-abdominal intestinal duplications. J Pediatr Surg 45:1554-1558, 2010.

Danzer E, Gerdes M, Bernbaum J, D’Agnostino J, Bebbington M, Siegle J, Hoffman C, Rintoul NE, Flake AW, Adzick NS, Hedrick HL: Neurodevelopmental outcome of infants with congenital diaphragmatic hernia enrolled prospectively in an interdisciplinary follow-up program. J Pediatr Surg 45:1759-1766, 2010.

Wilson RD, Kamerand K, Johnson MP, Flake AW, Bebbington M, Hedrick HL, Adzick NS: Reproductive outcomes in subsequent pregnancies after a pregnancy complicated by maternal-fetal surgery. Am J Ob Gyn 203: 209.e1-6, 2010.

Danzer E, Gerdes M, Bebbington MW, Zarnow DM, Adzick NS, Johnson MP: Preschool neurodevelopmental outcome of children following fetal myelomeningocele closure. Am J Ob Gyn 202: 450; e1-9, 2010.

Laje P, Stanley CA, Adzick NS: Intussusception after pancreatectomy in children: A case series. J Pediatr Surg 45:1496-1499, 2010.

Danzer E, Gerdes M, D'Agostino JA, Bernbaum J, Siegle J, Hoffman C, Rintoul NE, Liechty KW, Flake AW, Adzick NS, Hedrick HL: Prospective, interdisciplinary follow-up of children with prenatally diagnosed giant omphalocele: Short-term neurodevelopmental outcome.  J Pediatr Surg 45:718-723, 2010.

Laje P, Halaby L, Adzick NS, Stanley CA: Necrotizing enterocolitis in neonates receiving octreotide for the management of congenital hyperinsulinism. Pediatric Diabetes 11:142-147, 2010.

Adzick NS: Fetal myelomeningocele: Natural history, pathophysiology, and in utero intervention. Sem Fetal Neonatal Med 15:9-15, 2010.

Adzick NS: Open fetal surgery for life-threatening fetal anomalies. Sem Fetal Neonatal Med 15:1-8, 2010.

Danzer E, Finkel RS, Rintoul NE, Bebbington MW, Schwarz ES, Zarnow DM, Adzick NS, Johnson MP: Reversal of hindbrain herniation after maternal-fetal surgery for myelomeningocele subsequently reduces the incidence and severity of brain-stem dysfunction and cranial nerve compression. Neuropediatrics 41:140-3, 2010.

2009

Nallasamy S, Davidson SL, Howell LJ, Macdonald J, Hedrick HL, Flake AW, Crombleholme TM, Adzick NS, Young TL: The effects of fetal surgery on retinopathy of prematurity development. Ophthalmology and Eye Diseases. Ophthalmology and Eye Diseases 1: 13-19, 2009.

Adzick NS: Management of fetal lung lesions. Clinics Perinatology 36:363-376, 2009.

Husler MR, Danzer E, Sutton L, Johnson MP, Bebbington M, Adzick NS, Wilson RW: Prenatal diagnosis and postnatal outcome of spinal defects without Arnold-Chiari II malformation. Prenatal Diagnosis 29:1050-1057, 2009.

Danzer E, Zhang M, Watanabe M, Bebbington MW, Radu A, Liechty KW, Adzick NS, Flake AW: Amniotic fluid levels of glial acidic fibrillary protein in fetal rats with retinoic acid induced myelomeningocele: A potential marker for spinal cord injury.  J Am College Surgeons 209:S63, 2009.

Husler MR, Wilson RD, Hori SC, Coleman BG, Bebbington ME, Mann SE, Adzick NS, Johnson MP: When is fetoscopic release of amniotic bands indicated? Review of outcome of cases treated in utero and selection criteria for fetal surgery. Prenatal Diagnosis 29:457-463, 2009.

Danzer E, Ernst L, Rintoul NE, Johnson MP, Adzick NS, Flake AW: In utero meconium passage in fetuses and newborns with myelomeningocele. Journal Neurosurg Ped 3:141-146, 2009.

Victoria T, Kramer SS, Markowitz R, Servaes S, Mong A, Jaramillo D:, Adzick NS  Esophageal obstruction and intra-cardiac "mass" in association with omphalocele closure. J Pediatr Surg 44:448-463, 2009.

Danzer E, Gerdes M, Bebbington MW, Sutton LE, Melchionni J, Adzick NS, Johnson MP: Lower extremity neuromotor function and short-term ambulatory potential following in utero myelomeningocele surgery. Fetal Diagnosis and Therapy 25:47-53, 2009.

Wilson RD, Hedrick HL, Flake AW, Johnson MP, Bebbington MW, Mann S, Rychik J, Liechty K, Adzick NS: Sacrococcygeal teratoma: Prenatal surveillance, growth, and pregnancy outcome. Fetal Diagnosis and Therapy 25:15-20, 2009.

2008

Mong A, Johnson AM, Kramer SS, Coleman BG, Hedrick HL, Krieger P, Flake AW, Johnson MP, Wilson RD, Adzick NS, Jaramillo D: Congenital High Airway Obstruction Syndrome: MR/US findings, effect on management, and outcome. Pediatric Radiology 38:1171-1179, 2008.

Danzer E, Adzick NS, Rintoul NE, Zarnow DM, Schwartz ES, Melchionni J, Ernst LM, Sutton LN, Flake AW, Johnson MP: Intradural inclusion cysts following in utero closure of myelomeningocele: Clinical implications and follow-up. Journal of Neurosurgery: Pediatrics 2:406-413, 2008.

Ganesh A, Adzick NS, Foster T, Cucchiaro G: Efficacy of addition of fentanyl to epidural bupivicaine on postoperative analgesia following thoracotomy for lung resection in infants. Anesthesiology 109:90-894, 2008.

Danzer E, Davey MG, Kreiger PA, Ruchelli ED, Johnson MP, Adzick NS, Flake AW, Hedrick HL: Fetal tracheal occlusion for severe congenital diaphragmatic hernia: A morphometric study of lung parenchyma and muscularization of pulmonary arterioles. J Pediatr Surg 43:1767-1775, 2008.

Biard J-M, Schwarz U, Davey MG, Danzer E, Johnson MP, Flake AW, Hedrick HL: Main bronchus occlusion for treatment of congenital diaphragmatic hernia in fetal lambs. J Pediatr Surg 43:620-627, 2008.

Tiblad E, Wilson RD, Carr M, Flake AW, Hedrick H, Johnson MP, Bebbington MW, Mann S, Adzick NS: OEIS sequence: A rare congenital anomaly with prenatal evaluation and postnatal outcome in six cases. Prenatal Diagnosis 28:141-147, 2008.

Fichter A, Dornseifer U, Henke J, Schneider KTM, Kovacs L, Biemer E, Bruner J, Adzick NS, Harrison MR, Papadopulos N: Fetal spina bifida repair: Current trends and prospects of intrauterine neurosurgery. Fetal Diagnosis and Therapy 23:271-286, 2008.

Danzer E, Radu A, Robinson LE, Volpe MV, Adzick NS, Flake AW: Morphological analysis of the neuromuscular development of the anorectal unit in fetal rats with retinoic acid induced myelomeningocele. Neuroscience Letters 430:157-62, 2008.

Badillo AT, Hedrick HL, Wilson RD, Danzer E, Bebbington MW, Johnson MP, Liechty KW, Flake AW, Adzick NS: Prenatal ultrasonographic gastrointestinal abnormalities in fetuses with gastroschisis do not correlate with postnatal outcomes.  J Pediatr Surg 43:647-653, 2008.

Tsai AY, Liechty KW, Hedrick HL, Bebbington M, Wilson RD, Johnson MP, Howell LJ, Flake AW, Adzick NS: Outcomes following postnatal resection of prenatally diagnosed asymptomatic cystic lung lesions.  J Pediatr Surg 43:513-517, 2008.

Peranteau WH, Merchant AM, Hedrick HL, Liechty KW, Howell LJ, Flake AW, Wilson RD, Johnson MP, Bebbington MW, Adzick NS: The prenatal course and postnatal management of peripheral bronchial atresia: Association with congenital cystic adenomatoid malformation of the lung. Fetal Diagnosis and Therapy 24:190-196, 2008.

Danzer E, Davey MG, Kreiger P, Ruchelli ED, Johnson MP, Adzick NS, Flake AW, Hedrick HL: Fetal tracheal occlusion in patients with severe congenital diaphragmatic hernia: A morphologic study of lung architecture and arterial muscularization.  J Pediatr Surg 43:1767-1775, 2008.

2007

Bebbington MW, Danzer E, Hedrick HL, Flake AW, Wilson RD, Johnson MP, Adzick NS: Serial measurement of lung head ratio (LHR) does not predict survival in left-sided congenital diaphragmatic hernia (CDH). Ultrasound Obstet Gynecol 30:435, 2007.

Hardy OT, Hernandez-Pampaloni M, Saffer JR, Scheuermann J, Ernst L, Freifelder R, Zhuang Hongming, MacMullen C, Becker S, Adzick NS, Divgi C, Alavi A, Stanley CA: Accuracy of [18F]-fluorodopa PET for diagnosing and localizing focal congenital hyperinsulinism. J Clin Endocrinol Metab 92:4706-4711, 2007.

Husler M, Wilson RD, Rychik J, Bebbington MW, Johnson MP, Mann S, Hedrick HL, Adzick NS: Congenital cystic adenomatoid malformation and conotruncal heart defects: Is there a genetic association? Prenatal Diagnosis 27:1123-1128, 2007.

Hedrick HL, Danzer E, Merchant A, Bebbington MW, Zhao H, Flake AW, Johnson MP, Liechty KW, Howell LJ, Wilson RD, Adzick NS: Liver position and lung-to-head ratio for prediction of extracorporeal oxygenation and survival in isolated left congenital diaphragmatic hernia. Am J Ob Gyn 197:422-423.e1-4, 2007.

Davey MG, Shegu S, Danzer E, Ruchelli E, Adzick NS, Flake AW, Hedrick HL: Pulmonary artery muscularization is reduced by fetal glucocorticoids in lambs with diaphragmatic hernia following tracheal occlusion. Am J Ob Gyn 197:381-382. e1-4, 2007.

Pressey TL, Wilson RD, Kasperski S, Bebbington MW, Adzick NS: Prenatal diagnosis of partial trisomy 1q and Monosomy X in a fetus with a congenital lung lesion and hydrops fetalis. American Journal of Medical Genetics 143:1104-1107, 2007.

Ilagan JG, Wilson RD, Johnson MP, Hedrick HL, Flake AW, Bebbington M, Adzick NS: Pregnancy outcomes following bipolar umbilical cord coagulation for selective termination in complicated monochorionic multiple gestations. Fetal Diagnosis and Therapy 23:145-150, 2007.

Nichol PF, Adzick NS: Gallstone ileus 20 years after Kasai procedure using a stapled anti-reflux valve. J Pediatr Surg 42:264-266, 2007.

Merchant AM, Peranteau W, Wilson RD, Johnson MP, Bebbington M, Hedrick HL, Howell LJ, Flake AW, Adzick NS: Case report: Postnatal chest wall deformities after fetal thoracoamniotic shunting for congenital cystic adenomatoid malformation. Fetal Diagnosis and Therapy 22:435-439, 2007.

Mann S, Wilson RD, Bebbington MW, Adzick NS, Johnson MP: Antenatal diagnosis and management of congenital cystic adenomatoid malformation. Sem Fetal Neonatal Med 12:477-481, 2007.

Peranteau WH, Wilson RW, Liechty KW, Johnson MP, Bebbington MW, Hedrick HL, Flake AW, Adzick NS: The effect of maternal betamethasone on prenatal congenital cystic adenomatoid malformation growth and fetal survival. Fetal Diagnosis and Therapy 22:365-371, 2007.

Netta DA, Wilson RD, Visintainer P, Johnson MP, Hedrick HL, Flake AW, Adzick NS: Gastroschisis: Growth and prenatal surveillance. Fetal Diagnosis and Therapy 27:352-357, 2007.

Wilson RD, Johnson MP, Bebbington M, Flake AW, Hedrick HL, Sutton LN, Adzick NS: Does a myelomeningocele sac compared to no sac increase neonatal morbidity after maternal-fetal surgery? Fetal Diagnosis and Therapy 22:348-351, 2007.

Peranteau WH, Bathaii SM, Pawel B, Hardy O, Alavi A, Stanley CA, Adzick NS: Multiple ectopic lesions of focal islet adenomatosis identified by PET scan in an infant with congenital hyperinsulinism. J Pediatr Surg 42:188-192, 2007.

Danzer E, Johnson MP, Bebbington M, Simon EM, Wilson RD, Bilaniuk LT, Sutton LN, Adzick NS: Fetal head biometry assessed by fetal magnetic resonance imaging following in utero myelomeningocele repair. Fetal Diagnosis and Therapy 22:1-6, 2007.

Danzer E, Kidoo DA, Redden RA, Robinson L, Radu A, Zderic SA, Doolin EJ, Adzick NS, Flake AW: Structural and functional characterization of bladder smooth muscle in fetal rats with retinoic acid induced myelomeningocele. Am J Physiol Renal Physiol 292:F197-206, 2007.

2006

Davey MG, Danzer E, Schwarz U, Robinson L, Shegu S, Adzick NS, Flake AW, Hedrick HL: Prenatal glucocorticoids improves lung morphology and partially restores surfactant mRNA expression in lambs with diaphragmatic hernia undergoing fetal tracheal occlusion. Pediatric Pulmonology 41:1188-1196, 2006.

Danzer E, Radu A, Volpe MV, Adzick NS, Flake AW: Normal neuromuscular development of the lower gastrointestinal tract and anorectum in fetal rats with retinoic acid induced myelomeningocele: Implications for fetal surgery. J American College of Surgeons 203:S36, 2006.

Hussain K, Seppanen M, Nanto-Salonen K, Stanley CA, Adzick NS, Thornton P, Minn H: The diagnosis of ectopic focal hyperinsulinism of infancy with [18F] – DOPA Positron Emission Tomography. J Clin Endocrinol Metab 91:2839-42, 2006.

Howell LJ, Johnson MP, Adzick NS: Creating a state-of-the-art center for fetal diagnosis and treatment: Importance of a multidisciplinary approach. Progress in Pediatric Cardiology 22:121-127, 2006.

Danzer E, Robinson LE, Davey MC, Schwarz U, Volpe M, Adzick NS, Flake AW, Hedrick HL: Tracheal occlusion in fetal rats alters expression of mesenchymal nuclear transcription factors without affecting surfactant protein expression. J Pediatr Surg 41:774-80, 2006.

Davey MG, Schwarz U, Danzer E, Adzick NS, Flake AW, Hedrick HL: Prenatal glucocorticoids and exogenous surfactant therapy improve postnatal lung function in lambs with severe diaphragmatic hernia following prenatal tracheal occlusion. Pediatric Research 60:131-135, 2006.

Johnson MP, Gerdes M, Rintoul N, Howell LJ, Pasquariello P, Melchionni J, Sutton LN, Adzick NS: Maternal-Fetal surgery for myelomeningocele: Neurodevelopmental outcomes at two years of age. American Journal of Obstetrics-Gynecology 194:1145-1152, 2006.

Cucchiaro G, Adzick NS, Rose JB, Maxwell L, Watcha M: A comparison of epidural bupivacaine-fentanyl and bupivacaine-clonidine in children undergoing Nuss procedure.  Anesthesia and Analgesia 103:322-327, 2006.

Suchi M, MacMullen C, Thornton PS, Adzick NS, Ganguly A, Ruchelli ED, Stanley CA: Molecular and immunohistochemical analyses of focal form of congenital hyperinsulinism. Molecular Pathology 19:122-129, 2006.

Kreiger PA, Ruchelli ED, Mahboubi S, Hedrick HL, Adzick NS, Russo PA: Fetal pulmonary malformations: Defining histopathology. American Journal of Surgical Pathology 30:643-649, 2006.

Peranteau WH, Ganguly A, Steinmiller L, Thornton P, Johnson MP, Howell LJ, Adzick NS, Stanley CA: Prenatal diagnosis and postnatal management of diffuse congenital hyperinsulinism: A case report. Fetal Diagnosis and Therapy 21:515-518, 2006.

Liechty KW, Hedrick HL, Johnson MP, Wilson RD, Ruchelli ED, Howell LJ, Crombleholme TM, Flake AW, Adzick NS: Severe pulmonary hypoplasia associated with giant cervical teratoma. J Pediatr Surg 41:230-233, 2006.

Danzer E, Hubbard AM, Hedrick HL, Johnson MP, Wilson RD, Howell LJ, Crombleholme TM, Flake AW, Adzick NS: Diagnosis and characterization of fetal sacrococcygeal teratoma with prenatal MR imaging. Am J Roentgenology 187:W350-356, 2006.

2005

Wilson RW, Hedrick HL, Liechty KW, Flake AW, Johnson MP, Bebbington M, Adzick NS: Cystic adenomatoid malformation of the lung: Review of genetics, prenatal diagnosis, and in utero treatment. American Journal of Medical Genetics 140A:151-155, 2005.

Danzer E, Layne M, Gorman T, Radu A, Adzick NS, Flake A: Gastroschisis in mice lacking aortic carboxypeptidase-like protein is associated with a defect in neuromuscular development restricted to the eviscerated intestine. J American College of Surgeons: 201:S52, 2005.

Biard J-M, Johnson MP, Carr M, Wilson RD, Hedrick HL, Pavlock C, Schwarz U, Flake AW, Adzick NS: Long-term outcomes in children treated by prenatal vesicoamniotic shunting for lower urinary tract obstruction (LUTO).  Obstetrics and Gynecology 106:503-508, 2005.

Danzer E, Schwarz U, Wehrli S, Radu A, Adzick NS, Flake AW: Retinoic acid induced myelomeningocele in fetal rats: Characterization by histopathological analysis and magnetic resonance imaging. Experimental Neurology 194:467-75, 2005.

Keswani SG, Crombleholme TM, Rychik J, Tian Z, MacKenzie TC, Johnson MP, Wilson RD, Flake AW, Hedrick HL, Lowell LJ, Adzick NS: Impact of continuous intraoperative monitoring on outcomes in open fetal surgery. Fetal Diagnosis and Therapy 20:316-320, 2005.

Hedrick HL, Flake AW, Crombleholme TM, Howell LJ, Johnson MP, Wilson RD, Adzick NS: The ex utero intrapartum therapy (EXIT) procedure for high risk fetal lung lesions. J Pediatr Surg 40:1038-43, 2005.

Davey MG, Biard JM, Robinson L, Tsai J, Schwarz U, Danzer E, Adzick NS, Flake AW: Surfactant protein expression (mRNA and protein) is increased in the ipsilateral, but not contralateral lungs of fetal sheep with left-sided diaphragmatic hernias.  Pediatric Pulmonology 39:359-367, 2005.

Bailey PD, Rose JB, Keswani SG, Adzick NS, Galinkin JL: Does the use of fentanyl in epidural solutions for post-thoracotomy pain management in neonates affect clinical outcome?  J Pediatr Surg 40:1118-21, 2005.

Merchant AM, Hedrick HL, Crombleholme TM, Johnson MP, Wilson RD, Howell LJ, Adzick NS, Flake AW: Management of fetal mediastinal teratoma: A report of two cases. J Pediatr Surg 40:228-231, 2005.

Keswani SG, Crombleholme TM, Johnson MP, Flake AW, Hedrick HL, Howell LJ, Wilson RD, Pawel BR, Davis GH, Adzick NS: The prenatal diagnosis and management of mainstem bronchial atresia. Fetal Diagnosis and Therapy 20:74-78, 2005.

2004

Danzer E, Johnson MP, Wilson RD, Flake AW, Hedrick HL, Sutton LN, Adzick NS: Fetal brain biometry following in utero repair of myelomeningocele (MMC). Ultrasound in Obstetrics and Gynecology 24:606-611, 2004.

Mitchell LE, Adzick NS, Melchionne J, Pasquariello PS, Sutton LN, Whitehead AS: Spina bifida. Lancet 364:1885-1895, 2004.

Suchi M, Thornton PS, Adzick NS, MacMullen C, Ganguly A, Stanley CA, Ruchelli ED: Congenital hyperinsulinism: Intraoperative biopsy interpretation can direct the extent of pancreatectomy. American Journal of Surgical Pathology 28:1326-1335, 2004.

Kirsch AJ, Macarek EJ, Chaquor B, Quinn T, Zderic S, Flake AW, Crombleholme TM, Adzick NS, Canning D, Hubbard AM, Rosenbloom, Snyder HM, Howard PS: Molecular response of the bladder to obstruction. Adv Exp Med Biol 539:195-216, 2004.

Danzer E, Wehrli S, Schwarz U, Radu A, Adzick NS, Flake AW: Myelomeningocele in fetal rats induced by retinoic acid: Characterization by magnetic resonance imaging and histopathologic analysis. J Am Coll Surg 199:546, 2004.

Wilson RD, Johnson MP, Flake AW, Crombleholme TM, Hedrick HL, Wilson J, Adzick NS: Maternal reproductive outcomes in pregnancies following an open fetal surgery pregnancy.  Am J Ob Gyn 191:1430-1436, 2004.

Biard JM, Wilson RD, Johnson MP, Hedrick HL, Schwarz U, Flake AW, Crombleholme TM, Adzick NS: Prenatally diagnosed giant omphalocele: Short-term and long-term outcomes. Prenatal Diagnosis 24:434-439, 2004.

Rychik J, Tian Z, Ewing S, Cohen D, Howell LJ, Wilson RD, Johnson MP, Hedrick HL, Flake AW, Crombleholme TM, Adzick NS: Acute cardiovascular effects of fetal surgery in the human. Circulation 110:1549-1556, 2004.

Cucchiaro G, Markowitz SD, Kaye R, Adzick NS, Litman RO, Stanley CA, Watcha MF: Blood glucose control during selective arterial stimulation and venous sampling for localization of pancreatic focal adenomatous hyperplasia in anesthetized children. Anesthesia & Analgesia 99:1044-1048, 2004.

Sutton LN, Adzick NS: Fetal surgery for myelomeningocele. Clinical Neurosurgery 51:155-162, 2004.

Wilson RD, Baxter JK, Johnson MP, King M, Kasperski S, Crombleholme TM, Flake AW, Hedrick HL, Howell LJ, Adzick NS: Thoracoamniotic shunts: Fetal treatment of pleural effusions and congenital cystic adenomatoid malformations. Fetal Diagnosis and Therapy 19:413-420, 2004.

Stanley CA, Thornton PS, Ganguly A, MacMillen C, Underwood P, Bhatia P, Steinkrauss L, Kaye R, Ruchelli E, Suchi M, Adzick NS: Preoperative evaluation of infants with focal or diffuse congenital hyperinsulinism by intravenous acute insulin response tests and selective pancreatic arterial calcium stimulation. Journal of Clinical Endocrinology and Metabolism 89:288-296, 2004.

Hedrick HL, Crombleholme TM, Flake AW, Nance ML, von Allmen D, Howell LJ, Johnson MP, Wilson RD, Adzick NS: Right congenital diaphragmatic hernia: Prenatal assessment and outcome. J Pediatr Surg 39:319-323, 2004.

Adzick NS, Thornton PS, Stanley CA, Kaye RD, Ruchelli E: A multidisciplinary approach to the focal form of congenital hyperinsulinism leads to successful treatment by partial pancreatectomy.  J Pediatr Surg 39:270-275, 2004.

Hedrick HL, Flake AW, Crombleholme TM, Howell LJ, Johnson MP, Wilson RD, Adzick NS: Sacrococcygeal teratoma: Prenatal assessment, fetal intervention, and outcome.  J Pediatr Surg 39:430-438, 2004.

2003

Howell LJ, Adzick NS: Establishing a Fetal Therapy Center: Lessons learned.  Seminars in Pediatric Surgery 12:209-217, 2003.

Adzick NS, Walsh DS: Myelomeningocele: Prenatal diagnosis, pathophysiology, and management. Seminars in Pediatric Surgery 12:168-174, 2003.

Adzick NS, Kitano Y: Fetal surgery for lung lesions, congenital diaphragmatic hernia, and sacrococcygeal teratoma. Seminars in Pediatric Surgery 12:154-167, 2003.

Sutton LN, Adzick NS, Johnson MP: Fetal surgery for myelomeningocele.  Childs Nervous System 19:587-591, 2003.

Adzick NS: Management of fetal lung lesions. Clinics in Perinatology 30:481-492, 2003.

Kitano Y, von Allmen D, Kanai M, Adzick NS, Flake AW: Epinephrine inhibits tracheal occlusion induced lung growth in fetal sheep. Fetal Diagnosis and Therapy 18:333-337, 2003.

Olutoye O, Coleman B, Adzick NS, Flake AW: Abnormal umbilical cord Dopplers may predict impending demise in fetuses with sacrococcygeal teratoma. A report of 2 cases. Fetal Diagnosis and Therapy 18:428-431, 2003.

Lim FY, Crombleholme TM, Flake AW, Hedrick HL, Johnson MP, Adzick NS: Congenital High Airway Obstruction Syndrome (CHAOS): Natural history and management.  J Pediatr Surg 38:940-945, 2003.

Keswani SG, Johnson MP, Hori S, Howell LJ, Hedrick HL, Flake AW, Wilson RD, Adzick NS, Crombleholme TM: In utero limb salvage: Fetoscopic release of amniotic bands for threatened limb amputation. J Pediatr Surg 38:848-851, 2003.

Davey MG, Bouchard S, Mendoza JM, Schwarz U, Adzick NS, Hedrick HL, Flake AW: Temporary in utero tracheal occlusion does not restore normal postnatal respiratory function in fetal sheep with severe lung hypoplasia. Journal of Applied Physiology 94:1054-1062, 2003.

Adzick NS, Flake AW, Crombleholme TM: Management of congenital lung lesions. Seminars in Pediatric Surgery 12:147-153, 2003.

Adzick NS: Preface to Fetal Surgery. Seminars in Pediatric Surgery 12:145-146, 2003.

Davey MG, Hedrick HL, Mendoza JM, Doolin EJ, Adzick NS, Flake AW: Measurement of lung parenchymal volume and alveolar surface area in fetal sheep using computer-assisted stereology. Scanning 25:37-44, 2003.

Wilson RD, Johnson MP, Crombleholme TM, Flake AW, Hedrick HL, King M, Howell LJ, Adzick NS: Chorioamniotic membrane separation following open fetal surgery: Pregnancy outcome. Fetal Diagnosis and Therapy 18:314-320, 2003.

Walsh DS, Adzick NS: Fetal surgery for spina bifida.  Seminars in Neonatology 8:197-205, 2003.

Hedrick HL, Flake AW, Crombleholme TM, Howell LJ, Johnson MP, Wilson RD, Adzick NS: The history of fetal diagnosis and treatment: The Children’s Hospital of Philadelphia experience. Fetal Diagnosis and Therapy 18:65-82, 2003.

Tulipan N, Sutton LN, Bruner JP, Cohen BM, Johnson MP, Adzick NS: The effect of intrauterine myelomeningocele repair on the incidence of shunt-dependent hydrocephalus. Pediatric Neurosurgery 38:27-33, 2003.

Johnson MP, Adzick NS, Rintoul N, Crombleholme TM, Flake AW, Howell LJ, Hedrick HL, Wilson RD, Sutton LN: Fetal myelomeningocele repair: Short-term clinical outcomes. Am J Ob Gyn 189:482-487, 2003.

Hirschl RB, Fox W, Glick PL, Greenspan J, Smith K, Thompson A, Adzick NS: A prospective, randomized trial of perfluorocarbon-induced lung growth (PILG) in newborns with congenital diaphragmatic hernia. J Pediatr Surg 38:283-289, 2003.

Bouchard S, Davey MG, Rintoul NE, Walsh DS, Rorke LB, Adzick NS: Correction of hindbrain herniation and anatomy of the vermis following in utero repair of myelomeningocele in sheep. J Pediatr Surg 38:451-458, 2003.

2002

Coleman BG, Howell LJ, Crombleholme TM, Johnson MP, Adzick NS: Fetal therapy: State of the art. Journal of Ultrasound in Medicine 21:1257-1288, 2002.

Davey MG, Hedrick HL, Kanai M, Mendoza JM, Adzick NS, Flake AW: Pulmonary epithelial liquid uptake expressed in relation to alveolar surface area in reduced in fetal lambs following prolonged in utero tracheal occlusion. Pediatric Pulmonology 34:278-286, 2002.

Cohen MS, Rychik J, Bush DM, Tian Z-Y, Howell LJ, Adzick NS, Flake AW, Johnson MJ, Spray TL, Crombleholme TM: Influence of congenital heart disease on survival in children with congenital diaphragmatic hernia. Journal of Pediatrics 141:25-30, 2002.

Midrio P, Silberstein HJ, Bilaniuk LT, Adzick NS, Sutton LN: Prenatal diagnosis of terminal myelocystocele in the fetal surgery era. Neurosurgery 50:1152-5, 2002.

Rintoul N, Sutton LN, Hubbard AM, Cohen B, Melchionni J, Pasquariello PS, Adzick NS: A new look at myelomeningoceles: Functional level, vertebral level, shunting, and the implications for fetal intervention. Pediatrics 109:409-413, 2002.

Crombleholme TM, Coleman BG, Howell LJ, Liechty KW, Johnson MP, Flake AW, Hedrick HL, Adzick NS: Elevated cystic adenomatoid malformation volume ratio (CVR) predicts outcome in prenatal diagnosis of cystic adenomatoid malformation of the lung. J Pediatr Surg 37:331-338, 2002.

Bouchard S, Johnson MP, Flake AW, Adzick NS, Crombleholme TM: The EXIT procedure: Experience and outcome in 31 cases.  J Pediatric Surgery 37:418-426, 2002.

MacKenzie TC, Crombleholme TM, Johnson MP, Schnaufer L, Flake AW, Adzick NS: The management of prenatally diagnosed conjoined twins. J Pediatric Surgery 37:303-309, 2002.

2001

MacKenzie TC, Adzick NS: Advances in fetal surgery.  J Intensive Care Medicine 16:251-262, 2001.

Bouchard S, Rintoul NE, Davey MG, Walsh DS, Adzick NS: Correction of hindbrain herniation after in utero repair of myelomeningocele in sheep.  Surgical Forum 51:419-421, 2001.

Kanai M, Kitano Y, von Allmen D, Davies P, Adzick NS, Flake AW: Fetal tracheal occlusion in the rat model of nitrofen-induced congenital diaphragmatic hernia: Tracheal occlusion reverses the arterial structural abnormality. J Pediatric Surgery 36:839-845, 2001.

Meuli M, Liu Y, Liggitt, Kashani-Saber M, Knauer S, Meuli-Simmen C, Harrison MR, Adzick NS, Reddington J, Heath TD, Debs RJ: Efficient gene expression in skin wound sites following local plasmid injection.  Journal of Investigative Dermatology 116:131-135, 2001.

Walsh DW, Adzick NS, Sutton LN, Johnson MP: The rationale for in utero repair of myelomeningocele. Fetal Diagnosis and Therapy 16:312-322, 2001.

MacKenzie TC, Guttenberg ME, Nissenbaum HL, Johnson MP, Adzick NS: A fetal lung lesion consisting of bronchogenic cyst, bronchopulmonary sequestration, and congenital cystic adenomatoid malformation: The missing link?  Fetal Diagnosis and Therapy 16:193-195, 2001.

Sutton LN, Sun P, Adzick NS: Fetal neurosurgery. Neurosurgery 48:124-142, 2001.

Bouchard S, Russo P, Adzick NS: Expression of neuropeptides in normal and abnormal appendices. J Pediatr Surg 36:1222-1226, 2001.

Mackenzie TC, Howell LJ, Flake AW, Adzick NS: Management of prenatally diagnosed choledochal cysts. J Pediatr Surg 36:1241-1243, 2001.

Kitano Y, Kanai M, Davies P, von Allmen D, Yang EY, Radu A, Adzick NS, Flake AW: Lung growth induced by prenatal tracheal occlusion and its modifying factors: A study in the rat model of congenital diaphragmatic hernia. J Pediatr Surg 36:251-259, 2001.

2000

Sylvester KG, Nesbit M, Radu A, Herlyn M, Adzick NS, Crombleholme TM: Adenoviral-mediated gene transfer in wound healing: Acute inflammatory response in human skin in the SCID mouse model. Wound Repair and Regeneration 8:36-44, 2000.

Mahle WT, Rychik J, Tian ZY, Cohen MS. Howell LJ, Crombleholme TM, Flake AW, Adzick NS: Echocardiographic evaluation of the fetus with congenital cystic adenomatoid malformation. Ultrasound in Obstetrics and Gynecology 16:620-624, 2000.

Olutoye O, Adzick NS: Fetal surgery for myelomeningocele. Operative Techniques in Plastic and Reconstructive Surgery. 7:82-90, 2000.

Flake AW, Crombleholme TM, Johnson MP, Howell LJ, Adzick NS: Treatment of severe congenital diaphragmatic hernia by fetal tracheal occlusion: Clinical experience with 15 cases. Am J Ob Gyn 183:1059-1066, 2000.

Crombleholme TM, Sylvester K, Flake AW, Adzick NS: Salvage of a fetus with Congenital High Airway Obstruction Syndrome by ex utero intrapartum treatment (EXIT) procedure.  Fetal Diagnosis and Therapy 15:280-282, 2000.

Walsh DS, Hutchins GM, Radu A, Adzick NS: Histologic evaluation of fetal spinal cords in myelomeningocele. Surgical Forum 51:440-442, 2000.

Walsh DS, Hubbard AM, Olutoye OO, Crombleholme TM, Flake AW, Johnson MP, Adzick NS: Assessment of fetal lung volumes and liver herniation with magnetic resonance imaging in congenital diaphragmatic hernia. Am J Ob Gyn 183:1067-1069, 2000.

Walsh DS, Adzick NS: Fetal surgical intervention. Amer J Perinatology 17:277-283, 2000.

Lovvorn HN, Savani RC, Ruchelli E, Cass DL, Adzick NS: Serum hyaluronan and its association with unfavorable histology and aggressiveness of heterotransplanted Wilms’ tumor. J Pediatr Surg 35:1070-1078, 2000.

Adzick NS, Nance ML: Medical Progress: Pediatric Surgery. N Engl J Med 342:1651-1657 & 1726-1732, 2000.

Lovvorn HN, Crombleholme TM, Cass DL, Ruchelli E, Morgan MA, Adzick NS: Fetoscopic laser therapy in twin-twin transfusion syndrome with anterior placentation.  Ob Gyn (in press).

Kitano Y, Ruchelli E, Weiner S, Adzick NS: Hepatic mesenchymal hamartoma associated with mesenchymal stem villous hyperplasia of the placenta. Fetal Diagnosis and Therapy 15:134-138, 2000.

Liechty KL, Crombleholme TM, Adzick NS: Decreased IL-6 in scarless human fetal repair. Cytokines 12:671-676, 2000.

Liechty KW, Kim HB, Adzick NS, Crombleholme TM: Fetal wound repair in interleukin-10 deficient mice results in scar formation.  J Pediatr Surg 35:866-873, 2000.

Kitano Y, Quinn TM, Kanai M, Flake AW, Adzick NS, von Allmen D: Lung growth induced by tracheal occlusion in the sheep is augmented by airway pressurization. J Pediatr Surg 35:216-22, 2000.

Milner R, Kitano Y, Olutoye O, Flake AW, Adzick NS: Radiofrequency thermal ablation (RTA): A potential treatment for hydropic fetuses with a large chest mass. J Pediatr Surg 35:386-89, 2000.

Hubbard AM, Crombleholme TM, Adzick NS, Coleman BG, Meyer JS, Flake AW: Prenatal MRI evaluation of congenital diaphragmatic hernia. Amer J Perinatology 16:407-413, 2000.

Walsh DS, Adzick NS: Fetal intervention: Where we are, where we are going. Contemporary Pediatrics 17:33-55, 2000.

Olutoye O, Coleman B, Hubbard AM, Adzick NS: Prenatal diagnosis and management of congenital lobar emphysema. J Pediatr Surg 35:792-795, 2000.

Carpentieri DF, Guttenberg M, Quinn TM, Adzick NS: Subdiaphragmatic pulmonary sequestration: A case report with review of the literature.  Journal Perinatology 1:60-62, 2000.

1999

Kitano Y, Adzick NS: New developments in fetal lung surgery.  Current Opinion in Pulmonary Medicine. 5:383-389, 1999.

Sutton LN, Adzick NS, Bilaniuk LT, Johnson MP, Crombleholme TM, Flake AW: Improvement in hindbrain herniation by serial fetal MRI following fetal surgery for myelomeningocele.  JAMA 282:1826-1831, 1999.

Yingling C, Meuli M, Meuli-Simmen C, Hoffman K, Adzick NS: Assessment of sensory function in neonatal sheep with somatosensory evoked potentials.  I. Methodology and normative data.   Pediatr Surg International 15:530-534, 1999.

Yingling CD, Meuli-Simmen C, Meuli M, Timmel GB, Harrison MR, Adzick NS: Experimental fetal neurosurgery: Effects of in utero manipulations on somatosensory evoked potentials. Pediatr Surg International 15:535-539, 1999.

Liechty KW, Herlyn M, Nesbit M, Radu A, Adzick NS, Crombleholme TM: Adenoviral-mediated overexpression of platelet-derived growth factor-B corrects ischemic impaired wound healing.  J Invest Derm 113:375-383, 1999.

Cass DL, Lovvorn HN, Yang EY, Sylvester KG, Adzick NS: Regenerative capabilities of the fetal vascular wall.  Surgical Forum 50:468-469, 1999.

Walsh DS, Long P, Olutoye O, Crombleholme TM, Flake AW, Adzick NS: A new minimally invasive technique for fetal tracheal occlusion in congenital diaphragmatic hernia.  Surgical Forum 50:504-506, 1999.

Pameijer C, von Allmen D, Rhodes LA, Quinn TM, Adzick NS: Electrocardiographic monitoring in the management of fetal congenital malformations. Surgical Forum 50:503-504, 1999.

Kanai M, Kitano Y, Radu A, Adzick NS, Flake AW, von Allmen D: Effect of prenatal tracheal occlusion on pulmonary arterial structural changes in rats with nitrofen-induced congenital diaphragmatic hernia. Surgical Forum 50:567-568, 1999.

Kitano Y, Davies P, von Allmen D, Adzick NS, Flake AW: Prenatal tracheal occlusion induces lung growth in the hypoplastic lung: A study in the rat model of nitrofen-induced congenital diaphragmatic hernia.  Journal of Applied Physiology 87:769-775, 1999.

Howell LJ, Adzick NS: The essentials of a Fetal Treatment Center. Seminars in Perinatology 23:535-540, 1999.

Yang E, Flake AW, Adzick NS: Prospects for fetal gene therapy. Seminars in Perinatology 23:524-534, 1999.

Olutoye O, Adzick NS: Fetal surgery for myelomeningocele. Seminars in Perinatology 23:462-473, 1999.

Kitano Y, Flake AW, Crombleholme TM, Johnson MP, Adzick NS: Open fetal surgery for life-threatening fetal malformations.  Seminars in Perinatology 23:448-461, 1999.

Kitano Y, Adzick NS: New developments in fetal lung surgery.  Current Opinion in Pediatrics 11:193-199, 1999.

Milner R, Adzick NS: Perinatal management of fetal malformations amenable to surgical correction. Current Opinion in Ob Gyn 11:177-183, 1999.

Yang EY, Kim HB, Shaaban AF, Milner R, Adzick NS, Flake AW: Persistent postnatal transgene expression in both muscle and liver after fetal injection of recombinant adenovirus. J Pediatr Surg 34:766-773, 1999.

Flake AW, Crombleholme TM, Adzick NS: The current status and future potential of fetal intervention: Image is everything.  Computerized Med Imaging and Graphics 23:51-57, 1999.

Hubbard AM, Adzick NS, Crombleholme TM, Coleman BG, Howell LJ, Haselgrove JC, Mahboubi S: Congenital chest lesions: Diagnosis and characterization with prenatal MR.  Radiology 212:43-48, 1999.

Lovvorn HN, Nance ML, Ferry RJ, Stolte L, Baker L, O’Neill JA, Schnaufer L, Stanley CA, Adzick NS: Congenital hyperinsulinism and the surgeon: Lessons learned over 35 years. J Pediatr Surg 34:786-793, 1999.

Liechty KW, Quinn TM, Cass DL, Crombleholme TM, Flake AW, Adzick NS: Elevated PDGF-B in congenital cystic adenomatoid malformations requiring fetal resection. J Pediatr Surg 34:805-810, 1999.

Quinn TM, Sylvester KG, Kitano Y, Liechty KW, Jarret BP, Adzick NS, Flake AW: Transforming growth factor beta-2 is increased after fetal tracheal ligation.  J Pediatr Surg 34:701-705, 1999.

Liechty KW, Crombleholme TM, Weiner S, Bernick B, Flake AW, Adzick NS: Use of the Ex Utero Intrapartum Treatment Procedure for a large fetal neck mass in a twin gestation. Obstet Gyn 93:824-825, 1999.

Liechty KW, Sablich TJ, Adzick NS, Crombleholme TM: Recombinant adenoviral-mediated gene transfer in ischemic impaired wound healing.  Wound Repair and Regeneration 7:148-153, 1999.

Adzick NS, Scipione A: Pediatric surgical workload during the past decade: Impact on clinical activity and hospital finance at a Children’s Hospital.  J Pediatr Surg 34:133-136, 1999.

Lovvorn HN, Cheung DT, Nimni ME, Perelman N, Estes JM, Adzick NS: Deposition and crosslinking of  collagen during fetal and adult sheep wound repair.  J Pediatr Surg 34:218-223, 1999.

Yang EY, Cass DL, Sylvester KG, Wilson JM, Adzick NS: Fetal gene therapy: Efficacy, toxicity, and immunologic effects of early gestation recombinant adenovirus. J Pediatr Surg  34:235-241, 1999.

1998

Sylvester KG, Kitano Y, Radu A, Nesbit M, Herlyn M, Adzick NS, Crombleholme TM: Comparison of effects of adenoviral-mediated gene transfer of PDGF-B in diabetic mice and heterozygous controls. Surgical Forum 49:653-4, 1998.

Adzick NS, Sutton LN, Crombleholme TM, Flake AW: Successful fetal surgery for spina bifida. Lancet 350:1675-1676, 1998.

Ferro MM, Milner R, Cannizzaro C, Rodriguez S, Bonifacino G, Zapaterio J, Voto L, Adzick NS: Intrathoracic alimentary tract duplication cysts treated in utero by thoracoamniotic shunting. Fetal Diagnosis and Therapy 13:343-347, 1998.

Kitano Y, Yang EY, von Allmen D, Quinn TM, Adzick NS, Flake AW: Tracheal occlusion in the fetal               rat:  A new experimental model for the study of accelerated lung growth.  J Pediatr Surg  33:1741-1744, 1998.

Liechty KW, Adzick NS: Prospects for fetal therapy for spina bifida. Mental Retard Develop Disabilities 4:291-295, 1998.

Kirsch AJ, Quinn TM, Zderic SA, Duckett JW, Howard P, Flake AW, Crombleholme TM, Adzick NS, Canning DA, Hubbard A, Snyder HM, Macarak EJ: Bladder and renal effects of partial urethral obstruction in the fetal lamb.  J Urology 159(5):286-289, 1998.

Liechty KW, Crombleholme TM, Cass DL, Martin B, Adzick NS: Diminished interleukin-8 production in the fetal wound healing response.  J Surg Research 77:80-84, 1998.

Kitano Y, Sylvester K, Radu A, Nesbit M, Herlyn M, Adzick NS, Crombleholme TM: Treatment of  large excisional healing-impaired wounds in diabetic mice with a replication deficient adenovirus carrying the PDGF-B transgene (AD-CMV-PDGF-B).  Surgical Forum 49:651-3, 1998.

Yang EY, Kim HB, Shaaban AF, Milner R, Adzick NS, Flake AW: Fetal intramuscular delivery of recombinant adenovirus results in persistent postnatal transgene expression in both muscle and liver.  Surgical Forum 49:368-9, 1998.

Kitano Y, von Allmen D, Yang EY, Quinn TM, Kanai M, Adzick NS, Flake AW: Prenatal tracheal occlusion enhances lung growth in the nitrofen-induced rat CDH model.  Surgical Forum 49:587-9, 1998.

Lovvorn HN, Crombleholme TM, Drott H, Flake AW, Adzick NS: Maternal colloid osmotic pressure    after fetal surgery.  Surgical Forum 49:481-3, 1998.

Adzick NS, Harrison MR, Crombleholme TM, Flake AW, Howell LJ: Fetal lung lesions: Management and outcome.  Am J Obstet Gynecol 179:884-9, 1998.

Namba R, Meuli M, Sullivan KM, Le A, Adzick NS: The spontaneous repair of superficial articular cartilage defects in a fetal lamb model. J Bone Joint Surg 80A:4-10, 1998.

Yang EY, Adzick NS: Fetoscopy. Seminars in Laparoscopic Surgery 5:31-9, 1998.

Hubbard AM, Crombleholme TM, Adzick NS: Prenatal MRI evaluation of giant neck masses in preparation for the fetal EXIT procedure.  Amer Journal Perinatology  15:253-257, 1998.

Lovvorn HN, Cass DL, Sylvester KG, Crombleholme TM, Adzick NS, Savani RC: Hyaluronan receptor expression increases in fetal excisional skin wounds and correlates with fibroplasia.  J Pediatr Surg 33:1062-1070, 1998.

Sylvester KG, Rasanen J, Kitano Y, Flake AW, Crombleholme TM, Adzick NS: Fetal tracheal occlusion reverses the high vascular impedance in diaphragmatic hernia.  J Pediatr Surg 33:1071-1075, 1998.

Cass DL, Quinn TM, Yang EY, Liechty KW, Crombleholme TM, Flake AW, Adzick NS: Increased cell proliferation and decreased apoptosis characterizes congenital cystic adenomatoid malformation.  J Pediatr Surg 33:1043-1047, 1998.

Stelnicki EJ, Komuves LG, Kwong AO, Holmes D, Klein P, Rozenfeld S, Lawrence HJ, Adzick NS, Harrison MR, Largman C: HOX homeobox genes exhibit spatial and temporal changes in expression during human skin development. J Invest Derm 110:110-115, 1998.

Quinn TM, Hubbard AM, Adzick NS: Prenatal magnetic resonance imaging enhances prenatal diagnosis.  J Pediatr Surg  33:553-558, 1998.

Cass DL, Bullard KM, Sylvester KG, Yang EY, Sheppard D, Herlyn M, Adzick NS: Epithelial integrin expression is upregulated rapidly in human fetal wound repair. J Pediatr Surg 33:312-316, 1998.

Graf JL, Housley HT, Albanese CT, Adzick NS, Harrison MR: A surprising histologic evolution of preterm sacrococcygeal teratomas.  J Pediatr Surg 33:177-179, 1998.

1997

Bruch S, Adzick NS, Reiss R, Harrison MR: Prenatal therapy for pericardial teratoma. J Pediatr Surg 32:1113-1115, 1997.

Liechty KW, Crombleholme TM, Sylvester KG, Lovvorn HN, Kitano Y, Cass DL, Adzick NS:  Differential IL-6 production by fetal vs. adult fibroblasts.  Surgical Forum 47:707-709, 1997.

Quinn TM, Kirsch AJ, Zderic SA, Duckett JW, Howard P, Flake AW, Adzick NS, Canning DA, Snyder HM, Macarak EJ: Renal effects of partial bladder outlet obstruction in the fetal lamb.  Surgical Forum 47:764-766, 1997.

Stelnicki EJ, Komuves LG, Holmes D, Clavin W, Harrison MR, Adzick NS, Largman C: The human homeobox genes MSX-1, MSX-2, and MOX-1 are differentially expressed in the dermis and epidermis in fetal and adult skin. Differentiation 62:33-41, 1997.

Liechty KW, Crombleholme TM. Flake AW, Morgan MA, Kurth CD, Hubbard AM, Adzick NS: Intrapartum airway management for giant fetal neck masses: The EXIT procedure (Ex Utero Intrapartum Treatment).  Am J Ob Gyn 177:870-874, 1997.

Quinn TA, Adzick NS: Fetal surgery. Obstetr Gyn Clin North America. 24:143-157, 1997.

Yang EY, Cass DL, Sylvester KG, Flake AW, Wilson JM, Adzick NS: Liver-directed fetal gene therapy using recombinant adenoviral vectors: Successful readministration in mid-gestation sheep fetuses.  Surgical Forum 48:464-467, 1997.

Sylvester KG, Rasanen J, Kitano Y, Flake AW, Crombleholme TM, Adzick NS: Fetal tracheal occlusion reverses the high vascular impedance in diaphragmatic hernia.  Surgical Forum 48:649-651, 1997.

Cass DL, Yang EY, Liechty KW, Quinn TM, Crombleholme TM, Flake AW, Adzick NS: Increased cell proliferation and decreased apoptosis in congenital cystic adenomatoid malformation: Insights into pathogenesis.  Surgical Forum 48:659-661, 1997.

Meuli-Simmen C, Meuli M, Adzick NS, Ursell PC, Harrison MR: Latissimus dorsi flap procedure to cover myelomeningocele in utero: A feasibility study in human fetuses.  J Pediatr Surg 32:1154-1156, 1997.

Hubbard AM, Adzick NS, Crombleholme TM, Haselgrove JC: Left congenital diaphragmatic hernia: Value of prenatal MR imaging in preparation for fetal surgery.  Radiology 203:636-640, 1997.

Cass DL, Meuli M, Adzick NS: Scar Wars: Implications of fetal wound healing for the pediatric burn patient.  Pediatr Surg International 12: 484-489, 1997.

Graf JL, Bealer JF, Gibbs DL, Adzick NS, Harrison MR: Chorioamniotic membrane separation: A potentially lethal finding.  Fetal Diagnosis and Therapy 12:81-84, 1997.

Sylvester KG, Yang EY, Cass DL, Crombleholme TM, Adzick NS: Fetoscopic gene therapy for congenital lung disease. J Pediatr Surg 32:964-969, 1997.

Cass DL, Crombleholme TM, Howell LJ, Stafford PW, Adzick NS: Cystic lung lesions with systemic arterial blood supply: A hybrid of congenital cystic adenomatoid malformation and bronchopulmonary sequestration. J Pediatr Surg 32:986-990, 1997.

Cha I, Adzick NS, Harrison MR, Finkbeiner WE: Fetal congenital cystic adenomatoid malformation of the lung: A clinicopathologic study of eleven cases.  American J Surg Path   21:537-544, 1997.

Cass DL, Sylvester KG, Yang EY, Crombleholme TM, Adzick  NS: Myofibroblast persistence in fetal sheep wounds is associated with scar formation. J Pediatr Surg 32:1017-1022, 1997.

Stelnicki EJ, Bullard KM, Harrison MR, Cass DL, Adzick NS: A new in vivo model for the study of fetal wound healing.  Ann Plast Surg  39:374-80, 1997.

Harrison MR, Adzick NS, Bullard KM, Farrell JA, Howell LJ, Rosen MA, Sola A, Goldberg JD, Filly RA:  In utero repair of congenital diaphragmatic hernia: A prospective trial. J Pediatr Surg 32:1637-1642, 1997.

Bullard KM, Cass DL, Banda MJ, Adzick NS: TGF-beta1 decreases collagenase in healing human fetal skin. J Pediatr Surg 32:1023-1027, 1997.

Bullard K, Adzick NS, Harrison MR: Mediastinal window: A minimally invasive approach to aortopexy. J Pediatr Surg 32:680-681, 1997.

Mychaliska G, Bealer J, Graf J, Adzick NS, Harrison MR: Operating on placental support: The Ex Utero Intrapartum Treatment (EXIT) procedure.  J Pediatr Surg  32:327-331, 1997.

Cass DL, Bullard KM, Sylvester KG, Yang EY, Longaker MT, Adzick NS: Wound size and gestational age modulate scar formation in fetal wound repair.  J Pediatr Surg 32:411-415, 1997.

West DC, Shaw DM, Lorenz P, Adzick NS, Longaker MT: Fibrotic healing of adult and late gestation fetal wounds correlates with increased hyaluronidase activity and removal of hyaluronan.  Int J Biochem Cell Biol 29: 201-210, 1997.

Gibbs DL, Rice HE, Farrell JA, Adzick NS, Harrison MR: Familial congenital diaphragmatic hernia:  An autosomal recessive syndrome with a poor prognosis.  J Pediatr Surg  32:366-368, 1997.

Meuli-Simmen C, Meuli M, Yingling CD, Eiman T, Timmel GB, Buncke HJ, Linenweaver W, Harrison MR, Adzick NS: Midgestational sciatic nerve transection in fetal sheep results in absent nerve regeneration and neurogenic muscle atrophy. Plast Reconstr Surg  99:486-492, 1997.

Adzick NS, Crombleholme TM, Morgan MA, Quinn TM: A rapidly growing fetal teratoma.  Lancet 349:538, 1997.

Meuli M, Meuli-Simmen C, Hutchins GM, Seller MJ, Harrison MR, Adzick NS: The spinal cord lesion in human fetuses with myelomeningocele: Implications for fetal surgery.  J Pediatr Surg 32:448-452, 1997.

Vanderwall KJ, Kohl T, Adzick NS, Harrison MR, Silverman NH: Fetal diaphragmatic hernia: Echocardiography and clinical outcome. J Pediatr Surg  32:223-226, 1997.

Bullard KM, Sonne J, Hawgood S, Harrison MR, Adzick NS: Tracheal ligation increases cell proliferation but decreases surfactant protein production in fetal murine lungs in vitro.  J Pediatr Surg 32:207-213, 1997.

Graf J, Vanderwall K, Adzick NS, Harrison MR: Nitroglycerin attenuates the bowel damage of necrotizing enterocolitis in a rabbit model.  J Pediatr Surg 32:283-286, 1997.

Graf J, Gibbs D, Adzick NS, Harrison MR: Fetal hydrops following in utero tracheal occlusion.  J Pediatr Surg 32:214-216, 1997.

1996

Graf J, Gibbs D, Adzick NS, Harrison MR: Fetal hydrops following in utero tracheal occlusion.  J Pediatr Surg 32:214-216, 1997.

Gallo R, Kim C, Kokenyesi R, Adzick NS, Bernfield M: Syndecans-1 and -4 are locally and distinctly induced during wound repair of neonatal but not fetal skin. J Invest Derm 107:676-683, 1996.

Hoffman KM, Timmel GB, Meuli-Simmen C, Meuli M, Yingling CD, Adzick NS: Experimental fetal neurosurgery:  The normal neurology of neonatal lambs and abnormal findings after in utero manipulation.  Contemporary Topics in Laboratory Animal Medicine 35:53-56, 1996.

Cass DL, Bullard KM, Sylvester KG, Yang EY, Sheppard D, Herlyn M, Adzick NS: Epithelial integrin expression is rapidly upregulated in human fetal wound repair. Surgical Forum 47:765-767, 1996.

Bullard KM, Cass DL, Banda MJ, Adzick NS: TGF-beta1 decreases collagenase in healing human fetal skin. Surgical Forum 47:762-765, 1996.

Skarsgard ED, Meuli M, VanderWall KJ, Bealer JF, Adzick NS, Harrison MR: Fetal endoscopic tracheal occlusion ("Fetendo-Plug") for congenital diaphragmatic hernia.  J Pediatr Surg 31:1335-1338, 1996.

Meuli-Simmen C, Meuli M, Hutchins GM, Yingling CD, Timmel GB, Harrison MR, Adzick NS: The fetal spinal cord does not regenerate after in utero transection in a large mammalian model. Neurosurgery 39:555-561, 1996.

Bullard KM, Adzick NS: Pediatric thoracoscopy: A new vista. Pediatric Pulmonology 22:129-135,1996.

Harrison MR, Adzick NS, Flake AW, Vanderwall KJ,  Bealer  JF, Howell LJ, Farrell JA, Filly RA, Rosen MA, Sola A, Goldberg JD: Correction of congenital diaphragmatic hernia in utero VIII: Response of the hypoplastic lung to tracheal occlusion. J Pediatr Surg 31:1339-1348, 1996.

Vanderwall KJ, Bruch SW, Szabo Z, Meuli M, Adzick NS, Harrison MR: Fetal endoscopic (‘Fetendo”) tracheal clip.  J Pediatr Surg  31:1101-1104, 1996.

Bealer JF, Graf J,  Bruch SW,  Adzick NS, Harrison MR: Gastroschisis increases small bowel nitric oxide synthase activity. J Pediatr Surg 31:1043-1046, 1996.

Hedrick MH, Rice HE, Vanderwall KJ, Adzick NS, Harrison MR, Siebert J, Hoffman WY, Longaker MT: Delayed in utero repair of surgically created fetal cleft lip and palate, Plast Reconstr Surg  97:900-907, 1996.

Meuli M, Meuli-Simmen C, Hutchins GM, Yingling CD, Hutchins GM, Timmel GB, Harrison MR, Adzick NS: In utero repair of experimental myelomeningocele spares neurologic function at birth.  J Pediatr Surg 31:397-402, 1996.

Bruch SW, Adzick NS, Goldstein RB, Harrison MR: Challenging the embryogenesis of cloacal exstrophy.  J Pediatr Surg 31:768-770, 1996.

Metkus AP, Filly RA, Stringer MD, Harrison MR, Adzick NS: Sonographic predictors of survival in fetal diaphragmatic hernia.  J Pediatr Surg 31:148-152, 1996.

Lin RY, Adzick NS: The role of the fetal fibroblast and transforming growth factor beta in a model of human fetal wound repair.  Seminars Pediatr Surg  5:165-174, 1996.

1995

Bealer JF, Skarsgard ED, Hedrick MH, Meuli M, VanderWall KJ, Flake AW, Adzick NS, Harrison MR: The "PLUG" odyssey: Adventures in experimental tracheal occlusion.  J Pediatr Surg 30:361-365, 1995.

Bealer JF, Skarsgard ED, Toth TL, Gibbs D, Adzick NS, Harrison MR: Cervical sonomicrometry detects preterm labor. Surgical Forum 46:557-560, 1995.

Siebert JW, Sung JJ, Zirn J, Kamino H, Hedrick MH, Adzick NS, Gold LI, Longaker MT: Immunohistochemical localization of transforming growth factor beta isoforms during fetal wound healing. Surgical Forum 46:646-648, 1995.

Meuli-Simmen C, Meuli M, Yingling CD, Eiman T, Timmel GB, Buncke HJ, Linenweaver W, Harrison MR, Adzick NS: Failure of the fetal sciatic nerve to regenerate at midgestation. Surgical Forum 46:689-692, 1995.

Meuli M, Liu Y, Liggit D, Meuli-Simmen C, Knauer S, Harrison MR, Adzick NS, Debs RJ: Cutaneous gene expression after local DNA delivery. Surgical Forum 46:701-702, 1995.

Meuli M, Meuli-Simmen C, Hutchins GM, Yingling CD, Hoffman KM, Harrison MR, Adzick NS: In utero surgery rescues neurologic function at birth in sheep with spina bifida.  Nature Medicine 1:342-347, 1995.

Adzick NS, Harrison MR: The Unborn Surgical Patient.  Current Problems in Obstetrics, Gynecology, and Fertility, Mosby-Year Book;  6:173-220, 1995.

Lorenz HP, Lin RY, Longaker MT, Whitby DJ, Adzick NS: The fetal fibroblast: The effector cell for scarless fetal skin repair.  Plast Reconstr Surg 96:1251-1261, 1995.

Meuli-Simmen C, Meuli M, Hutchins GM, Harrison MR, Buncke HJ, Sullivan KM, Adzick NS: Fetal reconstructive surgery: Experimental use of latissimus dorsi flap to correct myelomeningocele in utero.  Plastic Reconstructive Surgery 96:1007-1011, 1995.

Lin RY, Sullivan KM, Argenta PA, Lorenz HP, Adzick NS: Exogenous transforming growth factor beta amplifies its own expression and induces scar formation in a model of human fetal skin repair.  Ann Surg  222:146-154, 1995.

Bealer JF, Raisanen J, Skarsgard ED, Long SR, Wong K, Filly RA, Adzick NS, Harrison MR: The incidence and spectrum of neurologic injury following open fetal surgery for congenital anomalies. J Pediatr Surg 30:1150-1154, 1995.

Skarsgard ED, Bealer JF, Meuli M, Adzick NS, Harrison MR: Fetal endoscopic surgery: The relationship between insufflating pressure and the placental circulation. J Pediatr Surg 30:1165-1168, 1995.

Lin RY, Argenta PA, Sullivan KM, Adzick NS: Diagnostic and prognostic role of basic fibroblast growth factor in the urine of Wilms' tumor patients.  Clinical Cancer Research 1:327-331, 1995.

VanderWall KJ, Bealer JF, Adzick NS, Harrison MR: Cyclic GMP relaxes the internal anal sphincter in Hirschsprung's disease.  J Pediatric Surg  30:1013-1016, 1995.

Meuli M, Meuli-Simmen C, Yingling CD, Hoffman KB, Harrison MR, Adzick NS: Creation of myelomeningocele in utero: A model of functional damage from spinal cord exposure in fetal sheep.  J Pediatr Surg  30:1028-1033, 1995.

Sullivan KM, MacGillivray TE, Meuli M, Adzick NS: An adult-fetal skin interface heals without scar formation in sheep.  Surgery 118:82-86, 1995.

Bootstaylor BS, Filly RA, Harrison MR, Adzick NS: Prenatal sonographic predictors of liver herniation in congenital diaphragmatic hernia.  J Ultrasound Med 14:515-520, 1995.

Stringer MD, Goldstein RB, Filly RA, Howell LJ, Sola A, Adzick NS, Harrison MR: Fetal diaphragmatic hernia without visceral herniation.  J Pediatr Surg  30:1264-1266, 1995.

Stringer MD, McKenna KM, Goldstein RB, Filly RA, Adzick NS, Harrison MR: Prenatal diagnosis of esophageal atresia.  J Pediatr Surg 30:1258-1263, 1995.

Meuli M, Lorenz HP, Hedrick MH, Sullivan KM, Harrison MR, Adzick NS: Scar formation in the fetal alimentary tract.  J Pediatr Surg 30:392-395, 1995.

Sullivan KM, Lorenz HP, Adzick NS: A model of human fetal skin repair is deficient in transforming growth factor beta.  J Pediatr Surg 30:198-203, 1995.

Lin RY, Argenta PA, Sullivan KM, Stern R, Adzick NS: Urinary hyaluronic acid is a Wilms' tumor marker.  J Pediatr Surg 30:304-308, 1995.

Metkus AP, Harrison MR, Sola A, Adzick NS: Cost per anomaly (CPA): What does a diaphragmatic hernia cost?  J Pediatr Surg 30:226-230, 1995.

1994

Hedrick MH, Estes JM, Sullivan KM, Bealer JF, Kitterman JA, Flake AW, Adzick NS, Harrison MR: Plug the lung until it grows (PLUG): A new method to treat congenital diaphragmatic hernia in the fetus. J Pediatr Surg 29:612-617, 1994.

Argenta PA, Lin RY, Sullivan KM, Adzick NS: Urinary basic fibroblast growth factor is a Wilms' tumor marker.  Surgical Forum 45:789-791, 1994.

Meuli M, Meuli-Simmen C, Yingling CD, Hoffman KB, Harrison MR, Adzick NS: A new model of myelomeningocele: Studies in the fetal lamb.  Surgical Forum 45:587-589, 1994.

VanderWall KJ, Bealer JF, Adzick NS, Harrison MR: Cyclic GMP relaxes the internal anal sphincter in Hirschsprung's disease.  Surgical Forum 45:657-659, 1994.

West DC, Shaw DM, Lorenz HP, Adzick NS, Longaker MT: Hyaluronidase activity in fetal and adult wounds.  Surgical Forum 45:753-754, 1994.

Lin RY, Sullivan KM, Argenta PA, Lorenz HP, Adzick NS: Species-specific in situ hybridization demonstrates that the human fetal fibroblast modulates scarless repair.  Surgical Forum 45:659-662, 1994.

Sullivan KM, MacGillivray TE, Meuli M, Adzick NS: An adult-fetal skin interface heals without scar formation in sheep.  Surgical Forum 45:662-664, 1994.

Lin RY, Sullivan KM, Argenta PA, Lorenz HP, Adzick NS: Scarless human fetal skin repair is intrinsic to the fetal fibroblast and occurs in the absence of an inflammatory response:  In situ hybridization and immunohistochemical studies. Wound Repair and Regeneration 2:297-305, 1994.

Babcook CJ, Hedrick MH, Filly RA, Goldstein RB, Callen PW, Harrison MR, Adzick NS: Gastroschisis: Can sonography of the fetal bowel accurately predict postnatal outcome?  J Ultrasound in Med 13:701-6, 1994.

Adzick NS: Fetal cystic adenomatoid malformation. Seminars Thoracic Cardiovasc Surg 6:247-252, 1994.

Sullivan KM, Adzick NS: Fetal surgery.  Clin Obstet Gyn 37:355-371, 1994.

Adzick NS, Harrison MR: Fetal surgical therapy.  Lancet 343:897-902, 1994.

Evans MI, Adzick NS, Johnson MP, Flake AW, Quintero R, Harrison MR: Fetal therapy - 1994.  Curr Opinion Ob Gyn 6:58-64, 1994.

Harrison MR, Adzick NS, Estes JM, Howell LJ: A prospective study of the outcome for fetuses with diaphragmatic hernia.  JAMA 271(5):382-384, 1994.

Adzick NS, Lorenz HP:  Cells, matrix, growth factors, and the surgeon:  The biology of scarless fetal wound repair.  Ann Surg 220:10-18, 1994.

Estes JM, Vande Berg JS, Adzick NS, MacGillivray TE, Desmouliére A, Gabbiani G: Phenotypic and functional features of myofibroblasts in fetal wounds. Differentiation, 56:173-181,1994.

Bealer JF, Natuzzi ES, Buscher C, Ursell PC, Flake AW, Adzick NS, Harrison MR: Nitric oxide synthase is deficient in the aganglionic colon of patients with Hirschsprung's disease.  Pediatrics 93:647-651, 1994.

Bealer JF, Natuzzi ES, Flake AW, Adzick NS, Harrison MR: The effect of nitric oxide on the colonic smooth muscle of patients with Hirschsprung's disease.  J Pediatr Surg 29:1025-1029, 1994.

Hill AC, Adzick NS, Stevens MB, Mori H, Husseini W, Heymann MA: Fetal lamb pulmonary hypoplasia: Pulmonary vascular and myocardial abnormalities.  Ann Thor Surg 57:946-951, 1994.

Sullivan KM, Hawgood S, Flake AW, Harrison MR, Adzick NS: Amniotic fluid phospholipid analysis in the congenital diaphragmatic hernia fetus.  J Pediatr Surg 29:1020-1024, 1994.

MacGillivray TE, Jennings RW, Rudolph AM, Ring EJ, Adzick NS, Harrison MR: Vascular changes with in utero correction of diaphragmatic hernia.  J Pediatr Surg 29:992-996, 1994.

Longaker MT, Whitby DJ, Ferguson MWJ, Harrison MR, Adzick NS: Adult skin in the fetal environment heals with scar formation.  Ann Surg 219:65-72, 1994.

Rice HE, Estes JM, Hedrick MH, Bealer JF, Harrison MR, Adzick NS: Congenital cystic adenomatoid malformation:  A sheep model of fetal hydrops.  J Pediatr Surg 29(5):692-696, 1994.

Hedrick MH, Martinez-Ferro M, Filly RA, Flake AW, Harrison MR, Adzick NS: Prenatal diagnosis of congenital high airway obstruction (CHAOS): Potential for perinatal intervention.  J Pediatr Surg 29:271-274, 1994.

MacGillivray TE, Adzick NS: Biliary atresia begins before birth.  Pediatr Surg International 9:116-117, 1994.

1993

Hedrick MH, Jennings RW, MacGillivray TE, Rice HE, Flake AW, Adzick NS, Harrison MR: Chronic fetal vascular access: A new approach to the care of the fetal patient.  Lancet 342:1086-7, 1993.

Qian JJ, Duncan BW, Adzick NS, Bhatnagar RS: Regulation of prolyl hydroxylase by ascorbic acid is mediated by polyADP-ribose synthesis. Cellular and Molecular Biol Res 39:525-533, 1993.

Kaban LB, Dodson TB, Stern M, Umeda H, Longaker MT, Adzick NS: Fetal cleft lip repair in rabbits:  Long-term clinical and cephalometric results.  Cleft Palate Craniofacial J 30:12-18, 1993.

Hedrick MH, Estes JM, Sullivan KM, Bealer JF, Flake AW, Adzick NS, Harrison MR: Plug the lung until it grows (PLUG):  A new method to treat congenital diaphragmatic hernia in the fetus.  Surgical Forum  44:644-646, 1993.

Sullivan KM, Lorenz HP, Adzick NS: The role of transforming growth factor beta in human fetal wound healing.  Surgical Forum 44:625-627, 1993.

Chang J, Longaker MT, Lorenz HP, Roberts AB, Harrison MR, Adzick NS, Banda MJ: Fetal and adult sheep fibroblast TGF-ß1 gene expression in vitro: Effects of hypoxia and gestational age.  Surgical Forum 44:720-722, 1993.

Adzick NS, Harrison MR: Fetal surgical techniques.  Seminars in Pediatr Surg 2:136-142, 1993.

Harrison MR, Adzick NS, Flake AW: Congenital diaphragmatic hernia: An unsolved problem.  Seminars Pediatr Surg 2:109-112, 1993.

Adzick NS: Fetal thoracic lesions.  Seminars Pediatr Surg 2:103-108, 1993.

Rice HE, Adzick NS: Prenatal diagnosis: Essentials for the pediatric surgeon.  Seminars Pediatr Surgery 2:84-91, 1993.

Howell LJ, Adzick NS, Harrison MR: The Fetal Treatment Center.  Seminars Pediatr Surg 2:143-146, 1993.

Adzick NS and Harrison MR: The developmental pathophysiology of surgical disease.  Seminars  Pediatr Surg 2:92-102, 1993.

Adzick NS: Preface to The Fetus as a Surgical Patient.  Seminars  Pediatr Surg 2:82-83, 1993.

MacGillivray TE, Harrison MR, Goldstein RB, Adzick NS: Disappearing fetal lung lesions.  J Pediatr Surg 28:1321-1325, 1993.

Adzick NS, Harrison MR: Management of the fetus with a cystic adenomatoid malformation.  World J Surgery 17:342-349, 1993.

Lorenz HP, Adzick NS: Scarless skin wound repair in the fetus.  West J Med 159:350-355, 1993.

Jennings RW, La Quaglia MP, Hendren WH, Adzick NS: Fetal neuroblastoma: Prenatal diagnosis and natural history.  J Pediatr Surg 28:1168-1174, 1993.

Estes JM, Adzick NS, Longaker MT, Harrison MR, Stern R: Hyaluronate metabolism undergoes ontogenetic transition during fetal development: Implications for scarless wound healing.  J Pediatr Surg 28:1227-1231, 1993.

Harrison MR, Adzick NS, Flake AW, Jennings RW, Estes JM, MacGillivray TE, Chueh JT, Golbus MS, Filly RA, Goldstein RB, Howell LJ: Correction of congenital diaphragmatic hernia in utero: VI.  Hard-earned lessons.  J Pediatr Surg 28:1411-1418, 1993.

Freund RM, Siebert JW, Cabrera J, Longaker MT, Eidelman Y, Adzick NS, Garg HG: Serial quantitation of hyaluronan and sulfated glycosaminoglycans in fetal sheep skin.  Biochem Mol Biol Int 29:773-784, 1993.

Harrison MR, Adzick NS, Flake AW, Jennings RW: The CDH two-step: A dance of necessity.  J Pediatr Surg 28:813-816, 1993.

Lorenz HP, Adzick NS, Harrison MR: Open human fetal surgery.  Advances in Surgery 26:259-273, 1993.

Adzick NS, Harrison MR, Flake AW, Howell LJ, Golbus MS, Filly RA: Fetal surgery for cystic adenomatoid malformation of the lung.  J Pediatr Surg 28:806-812, 1993.

Lorenz HP, Whitby DJ, Longaker MT, Adzick NS: Fetal wound healing: The ontogeny of scar formation in the non-human primate.  Ann Surg 217:391-6, 1993.

Jennings RW, Adzick NS, Longaker MT, Harrison MR: Radiotelemetric fetal monitoring during and after open fetal surgery.  Surg Gyn Obstet 176:59-64, 1993.

1992

Lorenz HP, Longaker MT, Whitby DJ, Harrison MR, Adzick NS: Scarless fetal skin repair is intrinsic to the fetal fibroblast.  Surgical Forum 43:694-6, 1992.

Jennings RW, MacGillivary TE, Rudolph AM, Ring EJ, Adzick NS, Harrison MR: Vascular considerations in correction of congenital diaphragmatic hernia.  Surgical Forum 43:629-31, 1992.

Hedrick MH, Jennings RW, MacGillivray TE, Flake AW, Lorenz HP, Estes JM, Roberts LJ, Adzick NS, Harrison MR: Endoscopic catheterization of placental vessels for chronic fetal vascular access.  Surgical Forum 43:504-5, 1992.

Adzick NS, Harrison MR: Fetal surgery: A new frontier.  Postgraduate General Surgery 4:48-56, 1992.

Lorenz HP, Adzick NS, Longaker MT, Stern R: Scarless fetal wound repair: A review.  Advances in Plastic and Reconstructive Surgery 9:83-101, 1992.

Adzick NS, Longaker MT: Scarless fetal healing: Therapeutic implications.  Ann Surg 215(1):3-6, 1992.

Duncan BW, Adzick NS, Moelleken BRW, Chua J, Bradley SM, Longaker MT, Levinsohn DG, Harrison MR, Kaban LB: An in utero model of craniosynostosis.  J Craniofacial Surg 3:70-8, 1992.

Kuller JA, Yankowitz J, Goldberg JD, Harrison MR, Adzick NS, Filly RA, Callen PW, Golbus MS. Outcome of antenatally diagnosed cystic adenomatoid malformation.  Am J Ob Gyn 167:1038-41, 1992.

Longaker MT, Stern M, Lorenz HP, Whitby DJ, Harrison MR, Adzick NS, Kaban LB: A model for fetal cleft lip repair in lambs.  Plast Reconstr Surg 90:750-6, 1992.

Estes JM, Whitby DJ, Lorenz HP, Longaker MT, Szabo Z, Adzick NS, Harrison MR: Endoscopic creation and repair of fetal cleft lip.  Plast Reconstr Surg 90:743-6, 1992.

Jennings RW, Adzick NS, Longaker MT, Lorenz HP, Estes JM, Harrison MR: New techniques in fetal surgery.  J Pediatr Surg 27:1329-33, 1992.

Jennings RW, Flake AW, Massan G, Pellegrini CA, Adzick NS, Harrison MR: A novel endoscopic transgastric fundoplication procedure for gastroesophageal reflux.  J Laparoendoscopic Surg 2:207-13, 1992.

Jennings RW, Lorenz HP, Duncan BW, Bradley SM, Harrison MR, Adzick NS: Adult to neonate lung transplantation:  Anatomic considerations.  J Pediatr Surg 27:1329-33, 1992.

Duncan BW, Eraklis AE, Adzick NS: Retroperitoneal alimentary tract duplications detected in utero.  J Pediatr Surg 27:1231-1233, 1992.

Estes JM, MacGillivray TE, Hedrick MH, Adzick NS, Harrison MR: Fetoscopic surgery for treatment of congenital anomalies.  J Pediatr Surg 27:950-954, 1992.

Longaker MT, Moelleken BRW, Cheng JC, Jennings RW, Gordon L, Adzick NS, Harrison MR, Simmons D: Fetal fracture healing in a lamb model.  Plast Reconst Surg 90:161-171, 1992.

Adzick NS: On the horizon: Neonatal lung transplantation.  Arch Dis Child 67:455-7, 1992.

Duncan BW, Howell L, Harrison MR, Adzick NS, deLorimier AA: Tracheostomy in children with emphasis on home care.  J Pediatr Surg 27:432-435, 1992.

Duncan BW, Adzick NS, deLorimier AA, Zoger S, Harrison MR: Necrotizing fascitis in children with acute lymphoblastic leukemia.  J Pediatr Surg 27:668-671, 1992.

Lorenz HP, Longaker MT, Perchoka LA, Jennings RW, Harrison MR, Adzick NS: Scarless wound repair: A human fetal skin model. Development 114:253-259, 1992.

1991

Adzick NS: A new Wilms' tumor marker.  Dialogues in Pediatric Urology 14:6-7, 1991.

Michaels BM, Piscatelli S, Siebert JW, Jennings RW, Longaker MT, Adzick NS: Amniotic fluid stimulates or inhibits fibroblasts, depending on gestational age.  Surgical Forum 42:656-658, 1991.

Moelleken BRW, Longaker MT, Cheng JC, Jennings RW, Levinsohn DG, Gordon L, Adzick NS, Harrison MR, Simmons D: Fetal fracture healing in a large animal model.  Surgical Forum 42:668-670, 1991.

Longaker MT, Bouhana KS, Roberts AB, Harrison MR, Adzick NS, Banda MJ: Regulation of fetal wound healing.  Surgical Forum 42:575-577, 1991.

Jennings RW, Adzick NS, Longaker MT, Lorenz HP, Estes JM, Harrison MR: Fetal intraosseous access: A new approach to accessing the fetal circulation during fetal surgery.  Surgical Forum 42:659-661, 1991.

Estes JM, Spencer EM, Longaker MT, Adzick NS: Insulin-like growth factor-II in ovine wound fluid: Developmental regulation.  Surgical Forum 42:659-661, 1991.

Crombleholme TM, Shiraishi H, Adzick NS, Langberg J, Silverman N, Harrison MR: A model of non-immune hydrops in fetal lambs: Complete heart block induced hydrops fetalis.  Surgical Forum 42:487-489, 1991.

Crombleholme TM, Adzick NS, Hardy K, Longaker MT, Duncan BW, Harrison MR: Pulmonary lobar transplantation in neonatal swine:  A model for the treatment of diaphragmatic hernia.  Current Surgery 48:148-149, 1991.

Longaker MT, Adzick NS: The biology and therapeutic implications of fetal wound healing.  Clinical Materials 8:223-227, 1991.

Rittenberg T, Longaker MT, Adzick NS, Ehrlich HP: Sheep amniotic fluid has a protein factor which stimulates human fibroblast populated collagen lattice contraction.  J Cell Physiol 149:444-450, 1991.

Stern M, Longaker MT, Adzick NS, Harrison MR, Stern R: Hyaluronidase in urine of Wilms' tumor patients.  J Natl Cancer Inst 83:1569-1574, 1991.

Longaker MT, Whitby DJ, Adzick NS, Kaban LB, Harrison MR: Fetal surgery for cleft lip: A plea for caution.  Plast Reconstr Surg 88:1087-1092, 1991.

Whitby DJ, Longaker MT, Adzick NS, Harrison MR, Ferguson MWJ: Rapid epithelialization of fetal wounds is associated with the early deposition of tenascin.  J Cell Science 99:583-586, 1991.

Longaker MT, Whitby DJ, Jennings RW, Duncan BW, Ferguson MWJ, Harrison MR, Adzick NS: Fetal diaphragmatic wounds heal with scar formation.  J Surg Res 50:375-85, 1991.

Burd DAR, Longaker MT, Rittenburg T, Adzick NS, Harrison MR, Ehrlich HP: In vitro fetal wound contraction:  The effect of amniotic fluid.  Br J Plast Surg 44:302-305, 1991.

Adzick NS, Longaker MT: Animal models for the study of fetal tissue repair. J Surg Res 51:216-222, 1991.

deLorimier AA, Adzick NS, Harrison MR: Amnion inversion in the treatment of giant omphalocele.  J Pediatr Surg 26:804-807, 1991.

Jennings RW, Adzick NS, Longaker MT, Duncan BW, Scheuenstuhl H, Hunt TK: Ontogeny of fetal sheep polymorphonuclear leukocyte phagocytosis.  J Pediatr Surg 26:853-855, 1991.

Longaker MT, Chiu ES, Adzick NS, Stern M, Harrison MR, Stern R: Studies in fetal wound healing:  V. A prolonged presence of hyaluronic acid characterizes fetal wound fluid.  Ann Surg 213:292-296, 1991.

Longaker MT, Adzick NS: The biology of fetal wound healing: A review.  Plast Reconstr Surg 87:788-98, 1991.

Longaker MT, Burd DAR, Gown AM, Yen TSB, Jennings RW, Duncan BW, Harrison MR, Adzick NS: Midgestational excisional fetal lamb wounds contract in utero.  J Pediatr Surg 26:942-948, 1991.

Harrison MR, Adzick NS: The fetus as a patient: Surgical implications.  Ann Surg 213:279-90, 1991.

Duncan BW, Harrison MR, Zanjani ED, Tarantal AF, Adzick NS, Longaker MT, Roberts LJ, Bigler ME, Roncarolo M-G: Immunologic evaluation of hematopoietic chimeric rhesus monkeys.  Transplantation Proceedings 23:841-843, 1991.

Adzick NS, Longaker MT: Scarless wound healing in the fetus: The role of the extracellular matrix.  Prog Clin Biol Res 365:177-192, 1991.

1990

Chiu ES, Longaker MT, Adzick NS, Stern M, Harrison MR, Stern R: Hyaluronic acid patterns in fetal and adult wound fluid.  Surgical Forum 41:636-639, 1990.

Longaker MT, Whitby DJ, Jennings RW, Duncan BW, Harrison MR, Ferguson MWJ, Adzick NS: Adult skin in the fetal environment heals with scar formation.  Surgical Forum 41:639-41, 1990.

Harrison MR, Adzick NS, Jennings RW, Duncan BW, Rosen MA, Filly RA, Goldberg JD, deLorimier AA, Golbus MS: Antenatal intervention for congenital cystic adenomatoid malformation.  Lancet 336:965-967, 1990.

Harrison MR, Adzick NS, Longaker MT, Goldberg JD, Rosen MA, Filly RA, Evans MI, Golbus MS: Successful repair in utero of a fetal diaphragmatic hernia after removal of herniated viscera from the left thorax.  N Engl J Med 322:1522-1524, 1990.

Burd DAR, Longaker MT, Adzick NS, Harrison MR, Ehrlich HP: Fetal wound healing in a large animal model: The deposition of collagen is confirmed.  Brit J Plast Surg 43:571-577, 1990.

Crombleholme TM, Adzick NS, Longaker MT, Charlton VE: Carotid artery reconstruction following extracorporeal membrane oxygenation.  Am J Diseases of Children 144:872-875, 1990.

deLorimier AA, Harrison MR, Hardy K, Howell L, Adzick NS:  Tracheobronchial obstructions in infants and children:  Experience with 45 cases.  Ann Surg 212:277-290, 1990.

Harrison MR, Adzick NS: Advice to a resident: A surgeon's notebook.  J Pediatr Surg 25:379-380, 1990.

Crombleholme TM, Harrison MR, Longaker MT, Langer JC, Adzick NS, Bradley SM, Duncan BW, Verrier ED: Complete heart block in fetal lambs I.: Technique and acute physiological response.  J Pediatr Surg 25:587-593, 1990.

Longaker MT, Adzick NS, Sadigh D, Hendin B, Stair SE, Duncan BW, Harrison MR, Spendlove R, Stern R: Hyaluronic acid-stimulating activity in the pathophysiology of Wilms' tumor. J Natl Cancer Inst 82:135-139, 1990.

Burd DAR, Longaker MT, Adzick NS, Harrison MR, Ehrlich HP: Fetal wound healing: An in vitro explant model.  J Pediatr Surg 25:898-901, 1990.

Crombleholme TM, Longaker MT, Adzick NS, Harrison MR, deLorimier AA: Mediastinal pancreatic pseudocysts in children.  J Pediatr Surg 25:843-845, 1990.

Crombleholme TM, Adzick NS, Longaker MT, Bradley SM, Duncan BW, Harrison MR: Pulmonary vascular resistance in neonatal swine: Response to right pulmonary artery occlusion, Isoproterenol, and Prostaglandin E1. J Pediatr Surg 25:861-866, 1990.

Farmer DL, Adzick NS, Crombleholme WR, Crombleholme TM, Longaker MT, Harrison MR: Fetal trauma: Relation to maternal injury.  J Pediatr Surg 25:711-714, 1990.

Longaker MT, Adzick NS, Crombleholme TM, Hall JL, Stair SE, Harrison MR, Stern R: Studies in fetal wound healing VII: Fetal wound healing may be modulated by the hyaluronic acid stimulating activity in amniotic fluid.  J Pediatr Surg 25:430-433, 1990.

Longaker MT, Harrison MR, Adzick NS:  Testing the limits of neonatal tracheal resection.  J Pediatr Surg 25:790-792, 1990.

Crombleholme TM, deLorimier AA, Way LW, Adzick NS, Harrison MR: The Puestow procedure for chronic pancreatitis in children.  J Pediatr Surg 25:749-754, 1990.

Longaker MT, Harrison MR, Adzick NS, Crombleholme TM, Langer JC, Salvatierra O, Halberg FE: Nephron-sparing approach to bilateral Wilms' tumor: In situ or ex vivo surgery and radiation therapy.  J Pediatr Surg 25:411-414, 1990.

Langer JC, Fitzgerald P, Filly RA, Golbus MS, Adzick NS, Harrison MR: Cervical cystic hygroma in the fetus: Clinical spectrum and outcome.  J Pediatr Surg 25:58-62, 1990.

Crombleholme TM, Adzick NS, Hardy K, Longaker MT, Duncan BW, Harrison MR: Pulmonary lobar transplantation in neonatal swine: A model for treatment of congenital diaphragmatic hernia. J Pediatr Surg 25:11-18, 1990.

Crombleholme TM, Adzick NS, Longaker MT, Duncan BW, Harrison MR: Reduced size lung transplantation in neonatal swine: Technique and short-term physiologic response.  Ann Thorac Surg 49:55-60, 1990.

Longaker MT, Whitby DJ, Adzick NS, Crombleholme TM, Duncan BW, Stern R, Harrison MR:  Studies in fetal wound healing VI.  Second and early third trimester fetal wounds demonstrate rapid collagen deposition without scar formation.  J Pediatr Surg 25:63-69, 1990.

Harrison MR, Langer JC, Adzick NS, deLorimier AA, Golbus MS, Filly RA, Rosen MA: Correction of congenital diaphragmatic hernia in utero V: Initial clinical experience.  J Pediatr Surg 25:47-57, 1990.

1989

Adzick NS, Shamberger RC, Winter HS, Hendren WH: Surgical treatment of pancreas divisum causing pancreatitis in children. J Pediatr Surg 24:54-58, 1989.

Crombleholme TM, Longaker MT, Langer JC, Bradley SM, Adzick NS, Harrison MR: Complete heart block and AV-sequential pacing in fetal lambs: The atrial contribution to cardiac output in the fetus.  Surgical Forum 40:268-270, 1989.

Duncan BW, Adzick NS, Bradley SM, Longaker MT, Levinsohn DG, Moelleken BR, Harrison MR, Kaban LB: An in utero model of craniosynostosis.  Surgical Forum 40:608-609, 1989.

Longaker MT, Adzick NS, Harrison MR: Fetal obstructive uropathy.  Brit Med Journal 299:325, 1989.

Langer JC, Adzick NS, Filly RA, Golbus MS, Harrison MR: Gastrointestinal obstruction in the fetus.  Archives of Surgery 124:1183-1187, 1989.

Adzick NS, Fisher JH, Hendren WH: Esophageal adenocarcinoma 20 years after esophageal atresia repair.  J Pediatr Surg 24:741-744, 1989.

Longaker MT, Chiu ES, Harrison MR, Crombleholme TM, Duncan BW, Adzick NS, Stern R: Studies in fetal wound healing IV.  Hyaluronic acid stimulating activity distinguishes fetal from adult wound fluid.  Annals of Surgery 210:667-672, 1989.

Adzick NS, Vacanti JP, Lillehei CW, Wilson JM, O'Rourke PP, Crone RK: Fetal diaphragmatic hernia: Ultrasound diagnosis and clinical outcome in 38 cases from a single medical center.  J Pediatr Surg 24:654-658, 1989. 

Bond SJ, Harrison MR, Slotnick RN, Anderson J, Flake AW, Adzick NS: Cesarean delivery and hysterotomy using an absorbable stapling device.  Obstet Gynecol 74:25-8, 1989.

1988

Saltzman DH, Adzick NS, Benacerraf BR: Fetal cystic adenomatoid malformation of the lung:  Apparent improvement in utero.  Obstet Gynecol 71:1000-1003, 1988.

Fine C, Adzick NS, Doubilet PM: Decreasing size of a congenital cystic adenomatoid malformation in utero: Case report.  J Ultrasound in Medicine 7:405-408, 1988.

1987

Langer JC, Harrison MR, Adzick NS: Congenital diaphragmatic hernia: Current controversies in prenatal and postnatal management.  Fetal Therapy 2:209-215, 1987.

Langer JC, Harrison MR, Adzick NS, Longaker MT, Crombleholme TM, Golbus MS, Anderson RL, Callen PW, Filly RA: Perinatal management of the fetus with an abdominal wall defect.  Fetal Therapy 2:216-221, 1987.

Benacerraf BR, Adzick NS: Diaphragmatic hernia: Ultrasound diagnosis and clinical outcome in 19 cases.  Amer J Obstet Gynecol 156:573-576, 1987.

Flake AW, Harrison MR, Sauer L, Adzick NS, Krummel TM, Laberge JM: Auxiliary transplantation of the fetal liver II A functional evaluation of an intra-abdominal model.  J Pediatr Surg 22:559-565, 1987.

Hu LM, Davies P, Adzick NS, Harrison MR, Reid LM: The effects of intrauterine pneumonectomy in lambs:  A morphometric study of the remaining lung at term.  Amer Rev Respir Disease 133:607-612, 1987.

Flake AW, Harrison MR, Adzick NS, Zanjani ED: Production of erythropoietin by the fetal liver in an adult environment.  Blood 70: 542-545, 1987.

Adzick NS, Harrison MR, Hu L, Davies P, Flake AW, Reid LM: Pulmonary hypoplasia and renal dysplasia in a fetal lamb urinary tract obstruction model.  Surgical Forum 38:666-668, 1987.

Glick PL, Harrison MR, Adzick NS, Webb HW, deLorimier AA: Gastric infarction secondary to small bowel obstruction: A preventable complication after Nissen fundoplication.  J Pediatr Surg 22:941-943, 1987.

Flake AW, Adzick NS, Troyer RL, Harrison MR: Transamniotic fetal feeding II: A model of intrauterine growth retardation using the relationship of "natural runting" to intrauterine position. J Pediatr Surg 22:816-819, 1987.

1986

Sauer L, Glick PL, Adzick NS, Harrison MR: Compensatory renal growth following nephrectomy in fetal lambs.  Surgical Forum 37:648-650, 1986.

Adzick NS, Harrison MR, Hu LM, Davies P, Reid LM: Compensatory lung growth after pneumonectomy in fetal lambs: A morphometric study.  Surgical Forum 37:309-311, 1986.

Harrison MR, Adzick NS, Nakayama DK, deLorimier AA: Fetal diaphragmatic hernia:  Pathophysiology, natural history and outcome.  Clini Obstet Gynecol 29:490-501, 1986.

Flake AW, Harrison MR, Adzick NS, Zanjani ED: Transplantation of fetal hematopoietic stem cells in utero:  The creation of hematopoietic chimeras.  Science 233:776-778, 1986.

Adzick NS, Harrison MR, deLorimier AA: Tapering duodenoplasty for megaduodenum associated with duodenal atresia.  J Pediatr Surg 21:311-312, 1986.

Adzick NS, Harrison MR, deLorimier AA: Surgical clip ligation of the patent ductus arteriosus in premature infants.  J Pediatr Surg 21:171-172, 1986.

Adzick NS, Harrison MR, Glick PL, deLorimier AA: Temporary cutaneous umbilical vesicotomy in premature infants with urethral obstruction.  J Pediatr Surg 21:158, 1986.

Flake AW, Harrison MR, Adzick NS, deLorimier AA: Ureteropelvic junction obstruction in the fetus.  J Pediatr Surg 21:1058-1063, 1986.

Flake AW, Harrison MR, Adzick NS, Laberge JM, Warsof S: Fetal sacrococcygeal teratoma.  J Pediatr Surg 21:563-566, 1986.

Flake AW, Troyer RL, Adzick NS, Harrison MR: Auxiliary transplantation of the fetal liver I.  Development of a sheep model.  J Pediatr Surg 21:515-520, 1986.

Flake AW, Troyer RL, Adzick NS, Harrison MR: Transamniotic fetal feeding III. Effects of nutrient infusion on fetal growth retardation. J Pediatr Surg 21:481-484, 1986.

Adzick NS, Harrison MR, Anderson JV, Flake AW, Villa RL: Fetal surgery in the primate III.  Maternal outcome after fetal surgery.  J Pediatr Surg 21:477-480, 1986.

1985

Adzick NS, Flake AW, Harrison MR: Recent advances in prenatal diagnosis and treatment. Pediatr Clin No Amer 32(5):1103-1116, 1985.

Adzick NS, Flake AW, Harrison MR: Experimental studies on prenatal treatment of congenital anomalies.  British J Hosp Med 34:1254-1259, 1985.

Adzick NS, Harrison MR, Flake AW, Laberge JM, Villa RL: Development of a fetal renal function test using endogenous creatinine clearance.  J Pediatr Surg 20:602-607, 1985.

Adzick NS, Harrison MR, Flake AW, deLorimier AA: Urinary extravasation in the fetus with obstructive uropathy.  J Pediatr Surg 20:608-615, 1985.

Adzick NS, Outwater KM, Harrison MR, Reid LM: Correction of congenital diaphragmatic hernia in utero IV. An early gestational model for pulmonary vascular morphometric analysis.  J Pediatr Surg 20:673-680, 1985.

Adzick NS, Harrison MR, Flake AW, Glick PL: Fetal urinary tract obstruction: Experimental pathophysiology.  Sem Perinatol 9:79-90, 1985.

Harrison MR, Adzick NS, Nakayama DK, deLorimier AA: Congenital diaphragmatic hernia: Fatal but fixable.  Sem Perinatol 9:103-112, 1985.

Adzick NS, Kim SH, Bondoc CC, Quinby WC, Remensnyder JP: Management of toxic epidermal necrolysis in a pediatric burn center.  Amer J Diseases of Children 139:499-502, 1985.

Glick PL, Harrison MR, Adzick NS, Filly RA, Callen PW, Mahoney BS, Anderson RL, Golbus MS, deLorimier AA: Management of the fetus with congenital hydronephrosis II: Diagnostic assessment and selection for treatment.  J Pediatr Surg 20:376-87, 1985.

Glick PL, Harrison MR, Adzick NS, Filly RA, Callen PW: The missing link in the pathogenesis of gastroschisis.  J Pediatr Surg 20:406-409, 1985.

Adzick NS, Harrison MR, Flake AW, Glick PL, Bottles K: Automatic uterine stapling device in fetal surgery:  Experience in a primate model.  Surg Forum 36:476-481, 1985.

Adzick NS, deLorimier AA, Harrison MR, Fisher DM: Major childhood tumor resection using hemodilution anesthesia and hetastarch.  J Pediatr Surg 20:372-375, 1985.

Adzick NS, Harrison MR, Glick PL, Beckstead JH, Villa RL, Scheuenstuhl H, Goodson WH III: Comparison of fetal, newborn, and adult rabbit wound healing by histologic, enzyme-histochemical, and hydroxyproline determinations.  J Pediatr Surg 20:315-319, 1985.

Adzick NS, Harrison MR, Glick PL, Nakayama DK, Manning FA, deLorimier AA: Diaphragmatic hernia in the fetus: Prenatal diagnosis and outcome in 94 cases.  J Pediatr Surg 20:357-361, 1985.

1984

Glick PL, Harrison MR, Adzick NS, Noall RA, Villa R: Correction of congenital hydronephrosis in utero IV.  In utero decompression prevents renal dysplasia.  J Pediatr Surg 19:649-657, 1984.

Glick PL, deLorimier AA, Adzick NS, Harrison MR: Colon interposition: An adjuvant operation for short gut syndrome.  J Pediatr Surg 19:719-725, 1984.

Adzick NS, Strom M, Gang D, Donahoe PK: Cryotherapy for subglottic hemangioma.  J Pediatr Surg 19:353-357, 1984.

Glick PL, Harrison MR, Halks-Miller M, Adzick NS, Nakayama DK, Edwards MSB: Correction of congenital hydrocephalus in utero II.  Efficacy of in utero shunting.  J Pediatr Surg 19:870-881, 1984.

Adzick NS, Harrison MR, Slate RK, Glick PL, Villa RL: Surface cooling and rewarming the fetus:  A technique for experimental fetal cardiac surgery.  Surg Forum 35:313-316, 1984.

Adzick NS, Harrison MR, Glick PL, Golbus MS, Anderson RL, Mahoney BS, Callen PW, Hirsch JH, Luthy DA, Filly RA, deLorimier AA: Fetal cystic adenomatoid malformation: Prenatal diagnosis and natural history.  J Pediatr Surg 19:649-657, 1984.

Adzick NS, Harrison MR, Glick PL, Villa RL, Finkbeiner W: Experimental pulmonary hypoplasia and oligohydramnios: Relative contributions of lung fluid and fetal breathing movements.  J Pediatr Surg 19:658-665, 1984.

1980

Takamoto S, Levine FH, Adzick NS, LaRaia PJ, Fallon JT, Austen WG, Buckley MJ: A comparison of single and multiple dose crystalloid and blood potassium cardioplegia during prolonged aortic occlusion.  J Thorac and Cardiovasc Surg 79:19-28, 1980.

Hanson EC, Levine FH, Adzick NS, Lees RS, Daggett WM, Austen WG, Buckley MJ: Early and late results of coronary artery bypass surgery in patients with hyperlipidemia.  J Thorac and Cardiovasc Surg 79:19-28, 1980.

1978

Chaudry IH, Adzick NS, Baue AE: Glucocorticoid effects on gluconeogenesis during hemorrhagic shock.  J Surg Res 24:26-34, 1978.

1975

Chaudry IH, Adzick NS, Sayeed MM, Baue AE: Effect of hydrocortisone and dexamethasone on xylose uptake in isolated rat soleus muscle.  Biochimica et Biophysica Acta 399:85-98, 1975.

Abstracts

1997

Crombleholme TM, Hubbard AM, Howell LJ, Jackson M, Morgan M, Adzick NS: EXIT procedure (Ex Utero Intrapartum Treatment) for giant fetal neck masses.  Am J Ob Gyn 176:S84, 1997.

1994

Adzick NS, Harrison MR, Flake AW, Filly RA, Goldberg JD, Howell LJ: Fetal lung lesions:  Management and outcome.  Am J Ob Gyn 170:399, 1994.

Sola A, Stringer MD, Goldstein RB, Adzick NS, Harrison MR. Congenital diaphragmatic hernia without sonographic evidence of in utero visceral herniation: A good prognostic indicator.  Pediatr Res 35:256A, 1994.

Stringer MD, Adzick NS, Harrison MR. Mode of delivery and outcome of neonates with gastroschisis.  Am J Ob Gyn 171:869, 1994.

1992

Adzick NS: A comparative analysis of healing of surgical cleft lip corrected in utero and in neonates (Discussion).  Plast Reconstr Surg 89:18-20, 1992.

Dong L, Charlton V, Adzick NS.  Carotid artery stenosis after ECMO repair: Associated factors.  Clin Res 40:65A, 1992.

1991

Tenhave A, Adzick NS, Schmidt BL, Stern R: Hyaluronic acid deposition in the human fetal kidney:  A paradigm for stromal-epithelial interactions in morphogenesis and tumorigenesis.  Clin Res 39:4a, 1991.

Longaker MT, Bouhana KS, Roberts AB, Harrison MR, Adzick NS, Banda MJ: Regulation of fetal wound healing.  Plast Surg Forum 14:296-297, 1991.

Longaker MT, Whitby DJ, Ferguson MWJ, Jennings RW, Lorenz HP, Harrison MR, Adzick NS: Adult skin in the fetal environment heals with scar formation.  Plast Surg Forum 14:346-8, 1991.



Crombleholme TM, Harrison MR, Smith EH, Longaker MT, Adzick NS, Zanjani ED, Cowan MJ: Induction of tolerance by in utero hematopoietic stem cell transplantation:  Results of mixed lymphocyte-fetal cell reactions in rhesus monkeys.  J Pediatr Surg 26:505, 1991.

1990

Liu X, Qian JJ, Zha J, Duncan BD, Longaker MT, Adzick NS, Bhatnagar RS: Modulation of prolyl hydroxylase by poly ADP-Ribose.  J Cell Biol 111(5):22a, 1990.

Stern M, Longaker MT, Adzick NS, Harrison MR, Stern R: Hyaluronic acid and childhood renal tumors.  J Natl Cancer Inst  82:135-137, 1990.

1989

Glick PL, Harrison MR, Adzick NS, Katz MM: Correction of congenital hydronephrosis V:  The effect of acute urinary obstruction on the distribution of intrarenal blood flow.  Ped Res 25:340a, 1989.

Longaker MT, Adzick NS, Sadigh D, Harrison MR, Stern R: Hyaluronic acid and its stimulating factor in the pathophysiology of Wilms' tumor: A new oncofetal tumor marker.  Cancer Res 30:229a, 1989.

1987

Hu LM, Davies P, Adzick NS, Harrison MR, Reid L: Lung growth after intrauterine bilateral ureteral obstruction.  Fed Proc 46:1151a, 1987.

1986

Outwater KM, Adzick NS, Davies P, Langleben D, Harrison MR, Reid LM: Congenital diaphragmatic hernia in fetal lambs and its in utero repair: Morphometric analysis of the pulmonary vasculature.  Pediatr Res 20:437a, 1986.

1974

Chaudry IH, Adzick NS, Fishman LJ, Sayeed MM, Baue AE: The effects of insulin on glucose uptake in soleus muscles of adrenalectomized rats in shock.  Federation Proceedings 33:261, 1974.

Books

Edited Books, Monographs and Journals
2015

Adzick NS (ed): Prenatal Diagnosis and Therapy for Spina Bifida. Fetal Diagnosis and Therapy, Volume 37, pp 161-250, 2015.

2013

Adzick NS (ed): Fetal Surgery: Current Status. Seminars in Pediatric Surgery, Volume 22, Number 1, February 2013, Elsevier.

2012

Coran AG, Adzick NS, Krummel TM, Laberge J-M, Shamberger RC (eds): Pediatric Surgery. Elsevier. 7th Edition, 2012.

2010

Adzick NS (ed): Advances in Fetal Surgery. Seminars in Fetal and Neonatal Medicine. February 2010, Elsevier.

2003

Adzick NS (ed): Fetal Surgery. Seminars in Pediatric Surgery, Volume 12, August 2003, WB Saunders.

2001

Harrison MR, Evans M, Adzick NS, Holzgreve W (eds): The Unborn Patient: The Art and Science of Fetal Therapy. 3rd Edition. W.B. Saunders Co, Philadelphia, PA. 2001.

1999

Adzick NS (ed): Fetal Surgery. Seminars in Perinatology, Volume 23, December 1999, WB Saunders.

1994

Adzick NS and Harrison MR: The Unborn Surgical Patient.  Current Problems in Surgery, Mosby-Year Book; Littleton, MA, 1994, 76 pp.

1993

Adzick NS and Harrison MR (eds): The Fetus as a Surgical Patient. Seminars in Pediatric Surgery, Volume 2, May 1993, WB Saunders, 61 pp.

1992

Adzick NS and Longaker MT (eds): Fetal Wound Healing.  Elsevier Science Publishing, New York, 1992.

Chapters

2017

Adzick NS, Laje P: Pancreatic Neoplasms in Children. In: Grosfeld J, Carachi R (eds): The Surgery of Childhood Tumors. 3rd Edition, Springer-Verlag, 2017, pp 303-321.

2012

Adzick NS, Farmer DL. Cysts of the lungs and mediastinum. In: Coran A, Adzick NS, Krummel TM, Laberge J-M, Shamberger RC, editors. Pediatric surgery, 7th ed. Philadelphia: Elsevier; 2012.

Adzick NS. The pancreas. In: Coran A, Adzick NS, Krummel TM, Laberge J-M, Shamberger RC, editors. Pediatric surgery, 7th ed. Philadelphia: Elsevier; 2012.

States LJ, Adzick NS. Localization of a focal lesion of congenital hyperinsulinism: Imaging and surgery. In: Stanley CJ, Shyng S, DeLeon D, editors. Monogenic hyperinsulinemic hypoglycemia disorders. Frontiers in diabetes series. Basel (Switzerland): S Karger AG; 2012.

2011

Danzer E, Rintoul NE, Adzick NS. Pathophysiology of neural tube defects. In: Polin RA, Fox WW, Abman SH, editors. Fetal and neonatal physiology, 4th ed. Philadelphia: Elsevier; 2011.

Adzick NS. Congenital hyperinsulinism. In: Mattei PM, editor. Fundamentals of pediatric surgery, 2nd ed. Springer-Verlag; 2011. p. 611- 16.

Mackenzie TC, Adzick NS. Perinatal diagnosis of surgical disease. In Puri P, editor. Newborn surgery, 3rd ed. Hodder Arnold; 2011. p. 46-59.

Adzick NS. Forward. In: Rychik J, Tian Z, editors. Fetal cardiovascular imaging: Atlas and DVD. Philadelphia: Elsevier; 2011.

Danzer E, Rintoul NE, Adzick NS. Pathophysiology of neural tube defects. In: Polin RA, Fox WW, Abman SH, editors. Fetal and neonatal physiology, 4th ed. Philadelphia: Elsevier; 2011. p. 1848-62.

2009

Adzick NS. Fetal thoracic lesions. In: Rodeck C, Whittle MJ, editors. Fetal medicine: Basic science and clinical practice, 2nd ed. Philadelphia: Elsevier; 2009. p. 429-36.

2006 

Adzick NS, Farmer DL. Cysts of the lungs and mediastinum. In: Grosfeld J, O’Neill J, Coran A, Fonkalsrud E, editors. Pediatric surgery, 6th ed. Philadelphia: Elsevier; 2006. p. 955-70.

Bebbington MW, Johnson MP, Wilson RD, Adzick NS. Open fetal surgery. In: van Vugt JMG, Shulman LP, editors. Prenatal medicine. New York: Taylor & Francis; 2006. p. 501-16.

Bruner JP, Wilson RD, Adzick NS, Wilkins-Haug L, Marshall AC, Quintero RA, et al. Intrauterine surgical techniques. In: Webster JG, editor. Encyclopedia of medical devices and instrumentation, 2nd ed. Hoboken: John Wiley & Sons; 2006. p. 171-81.

Cass DL, Adzick NS. Fetal surgery - open - CCAM. In: Evans MI, editor. Prenatal diagnosis: Genetics, reproductive risks, testing, and management. Stamford: Appleton & Lange; 2006. p. 627-32.

2005

Adzick NS, Krupnick A. The pregnant patient. In: Mulholland M, Greenfield L, Lillemoe K, Oldham K, Zelenock G, editors. Surgery: Scientific principles and practice, 2nd ed. Philadelphia: Lippincott Williams, & Wilkins; 2005, p. 2116-33.

2004

Adzick NS. Conjoined twins. In: Martinez-Ferro, M, Cannizzaro C, Rodriguez S, Rabasa C, editors. Neonatologia quirurgica. 2004. p. 775-84.

2003

MacKenzie TC, Adzick NS. Surgical management of prenatally diagnosed malformations. In: Nyberg D, McGahan J, Pretorius D, Pilu G, editors. Diagnostic ultrasound of fetal anomalies, 2nd ed. Philadelphia: Lippincott Williams, & Wilkins; 2003. p. 1001-13.

Walsh DS, Adzick NS. Fetal disorders and their prenatal management. In: Rudolph CD, Rudolph AM, Hostett MK, Lister G, Siegel NJ, editors. Rudolph’s pediatrics, 21st ed. New York: McGraw-Hill Medical; 2003. p. 77-9.

Mackenzie TC, Adzick NS. Prenatal diagnosis of surgical diseases. In: Puri P, editor. Newborn surgery, 2nd ed. Oxford (UK): Heinemann Medical Books; 2003. p.15-23.

Danzer E, Rintoul NE, Crombleholme TM, Adzick NS. Pathophysiology of neural tube defects. In: Polin RA, Fox WW, Abman SH, editors. Fetal and neonatal physiology, 3rd ed. Philadelphia: WB Saunders Company; 2003. p. 1771-84.

Adzick NS. Fetal wound healing. In: Polin RA, Fox WW, Abman SH, editors. Fetal and neonatal physiology, 3rd ed. Philadelphia: WB Saunders Company; 2003. p. 1604-9.

2002

Cass DL, Adzick NS. Fetal wound healing implications. In: Katowitz JA, editor. Pediatric oculoplastic surgery. New York: Springer, 2002, p. 31-42.

2001

Adzick NS. The fetus with a lung lesion. In: Harrison MR, Evans M, Adzick NS, Holzgreve W, editors. The unborn patient: The art and science of fetal therapy, 3rd ed. Philadelphia: W.B. Saunders Co.; 2001. p. 287-96.

Adzick NS, Harrison MR. Open fetal surgical techniques. In: Harrison MR, Evans M, Adzick NS, Holzgreve W, editors. The unborn patient: The art and science of fetal therapy, 3rd ed. Philadelphia: W.B. Saunders Co.; 2001.p. 247-58.

Krupnick A, Adzick NS. Wound healing. In: Kreisel D, Krupnick AS, Kaiser LR, editors. The surgical review: An integrated basic and clinical science study guide. Philadelphia: Lippincott-Raven; 2001. p. 110-22.

Krupnick A, Adzick NS. Burns. In: Kreisel D, Krupnick AS, Kaiser LR, editors. The surgical review: An integrated basic and clinical science study guide. Philadelphia: Lippincott-Raven; 2001. p. 123-38.

Adzick NS, Krupnick A. Surgery in the pregnant patient. In: Greenfield L, Lillemoe K, Mulholland M, Oldham K, Zelenock G, editors. Surgery: Scientific principles and practice. Philadelphia: Lippincott Williams, & Wilkins; 2001. p. 2217-34.

2000

Lovvorn H, Adzick NS. Fetal obstructive uropathy. In: Pollack HM, McClennan BL, editors. Clinical urography. Philadelphia: WB Saunders Co.; 2000.

1999

Quinn TM, Adzick NS. Fetal surgery. In: Knobil E, Neill JD, editors. Encyclopedia of reproduction. Academic Press; 1999. p. 344-51.

Cass DL, Adzick NS. Fetal cystic adenomatoid malformation. In: Rodeck C, Evans M, editors. Ultrasound and fetal therapy. New York: Parthenon Press; 1999. p. 49-60.

1998

Stern M, Longaker MT, Adzick NS, Kaban LB. Wound healing and regeneration in a fetal cleft lip model. In: Lynch SE, Genco RJ, Marx RE, editors. Tissue engineering. Chicago: Quintessence Publishing Co, Inc.; 1998. p. 55-70.

Adzick NS. Fetal surgery. In: Taeusch W, Ballard RA, editors. Diseases of the newborn, 7th ed. Philadelphia: WB Saunders Co.;1998. p. 126-33.

Yang E, Adzick NS. Fetal surgery. In: Burg FD, Ingelfinger JR, Wald ER, Polin RA, editors. Current pediatric therapy. Philadelphia: WB Saunders Co.; 1998. p. 361-68.

Cass DL, Adzick NS. Fetal versus adult wound repair. In: Clark RAF, Davidson J, Mustoe T, Steed D, editors. Textbook of wound care. Philadelphia: WB Saunders Co.; 1998.

1997

Jennings RW, Adzick NS, Harrison MR. Fetal intervention for obstructive uropathy. In: O'Donnell BA, Koff SA, editor. Paediatric urology, 3rd ed. Surrey (England): Butterworth Scientific; 1997. p. 330-38.

Duncan BW, Adzick NS. Prenatal diagnosis of surgical diseases. In Puri P, editor. Newborn surgery, 1st ed. Oxford (England): Heinemann Medical Books; 1997.  p. 15-25.

Adzick NS. Fetal and neonatal wound healing. In: Polin R, Fox W, editors. Fetal and neonatal physiology, 2nd ed. Philadelphia: WB Saunders Co.; 1997. p. 2015-21.

Adzick NS, Harrison MR. The fetus as patient. In: Oldham KT, Colombani PM, Foglia RP, editors. Surgery of infants and children: scientific principles and practice. Philadelphia: JB Lippincott Company; 1997.  p. 48-64.

Adzick NS, Hedrick M. Other surgical conditions. In: Fisk NM, Moise KJ, editors. Fetal therapy: Invasive and transplacental. Cambridge (England): Cambridge University Press; 1997. p. 303-16.

1996

Jennings RW, Adzick NS, Harrison MR. Foetal surgery. In: Freeman NV, Atwell JD, Burge DM, Griffiths M, editors. Surgery of the newborn. London (England): Churchill Livingstone; 1996. p. 73-84.

Adzick NS. Wound healing: biologic and clinical features. In: Sabiston DC, editor. Textbook of surgery: The biological basis of modern surgical practice, 15th ed. Philadelphia: WB Saunders Company; 1996. p. 207-20.

Duncan BW, Adzick NS. Prenatal diagnosis of surgical diseases. In: Puri P, editor. Operative neonatal surgery. Oxford (England): Heinemann Medical Books; 1996. p.126-35.

Cass DL, Adzick NS. Fetal wound healing renaissance. In: Hudson JW, editor. Oral and maxillofacial surgery clinics of North America. Philadelphia: Elsevier; 1996. 8:535-46.

MacGillivray TE, Adzick NS, Harrison MR. The surgery of fetal malformations. In: Spitzer AB, editor. Intensive care of the fetus and neonate. St. Louis: CV Mosby Publishing Company; 1996. p. 190-98.

1995

Longaker MT, Harrison MR, Adzick NS. Fetal surgery. In: Morris P, Malt RA, editors. Oxford textbook of surgery. New York: Oxford University Press USA; 1995. p. 2001-5.

Johnson MP, Harrison MR, Adzick NS, Reichler A, Evans MI. Fetal gene therapy. In: Rock J, Gant N, editors. Advances in obstetrics and gynecology. St. Louis: CV Mosby Publishing Company; 1994. p. 423-34.

Estes JM, Adzick NS, Harrison MR. Antenatal open surgery for the abnormal fetus. In: Sabbagha RE, editor. Diagnostic ultrasound applied to obstetrics and gynecology, 3rd ed. Philadelphia: JB Lippincott Company; 1994. p. 557-68.

deLorimier AA, Harrison MR, Adzick NS. Pediatric surgery. In: Way LW, editor. Current surgical therapy. Norwalk: Appleton-Lange; 1994. p. 1190-39.

Lorenz HP, Adzick NS. Wound healing: The biological and clinical essentials. In: Sabiston DC, editor. Essentials of surgery. Philadelphia: WB Saunders Company; 1994. p. 86-90.

Evans MI, Harrison MR, Adzick NS, Reichler A, Johnson MP. Surgical and medical interventions. In: Rock J, Gant N, editors. Advances in obstetrics and gynecology. St. Louis: CV Mosby Publishing Company; 1994. p. 401-22.

1993

Lorenz HP, Harrison MR, Adzick NS. Open fetal surgical interventions. In: Ludomirski A, editor. Therapeutic and diagnostic interventions in early life. Mt. Kisco: Futura Publishing Co.; 1993. p. 107-15.

Harrison MR, Adzick NS, Flake AW. The prenatal management of the fetus with a correctable defect. In: Callen PW, editor. Ultrasonography in obstetrics and gynecology, 3rd ed. Philadelphia: WB Saunders Co.; 1993. p. 536-47.

Estes JM, Adzick NS, Harrison MR. Fetoscopic surgery. In: Holcomb GW, editor. Pediatric endoscopic surgery. Norwalk: Appleton and Lange; 1993. p. 155-62.

Adzick NS, Harrison MR. Fetal surgery. In: Copeland EM, Levine BA, Howard RJ, Sugerman H, Warshaw AL, editors. Current practice of surgery. New York: Churchill Livingstone Inc.; 1993. Section XVIII, p. 1-13.

MacGillivray TE, Adzick NS. Lung transplantation in pediatrics. In: Lobe T, editor.  Surgical chest clinics of North America. Philadelphia: Elsevier; 1993. p. 569-82. 

1992

Adzick NS, Harrison MR. The fetus at surgery. In: Hobbins J, Mahoney J, Petrie R, Reece EA, editors. Medicine of the fetus and its mother. Philadelphia: JB Lippincott Company; 1992, p. 791-99.

Jennings RW, Adzick NS, Harrison MR. Fetal intervention for obstructive uropathy. In: O'Donnell BA, Koff SA, editor. Paediatric urology, 2nd ed. Surrey (England): Butterworth Scientific; 1992. p. 48-62.

Duncan BW, Adzick NS, Harrison MR. Fetal surgery. In: Iffy L, Apprizio J, Vintzileos A, editors. The textbook of operative obstetrics. New York: Pergamon Press; 1992. p 91-109.

Harrison MR, Adzick NS. In utero surgical interventions. In: Ashcraft K, Holder T, editors. Pediatric surgery, 2nd ed. Philadelphia: W.B. Saunders; 1992. p. 1003-13.

Adzick NS, Harrison MR. Antenatal open surgery for abnormal fetuses. In: Sabbagha RE, editor. Ultrasound applied to obstetrics and gynecology, 2nd ed. Philadelphia: JB Lippincott Co.; 1992. p. 366-75.

Lorenz HP, Longaker MT, Adzick NS. Immunologic and infectious factors influencing wound repair. In: Fonkalsrud EW, Krummel TM, editors. Infections and immunologic disorders in pediatric surgery. Philadelphia: W.B. Saunders; 1992. p. 103-11.

Adzick NS, Harrison MR. The fetal surgery experience. In: Adzick NS, Longaker Mt, editors. Fetal wound healing. New York: Elsevier Scientific; 1992. p. 1-24.

Adzick NS, Longaker MT. Characteristics of fetal tissue repair. In: Adzick NS, Longaker MT, editors. Fetal wound healing. New York: Elsevier Scientific; 1992, p. 53-70.

Adzick NS. Fetal animal and wound implant models. In: Adzick NS, Longaker MT, editors. Fetal wound healing. New York: Elsevier Scientific; 1992. p. 71-82.

Lorenz HP, Longaker MT, Adzick NS. Human fetal skin: ontogeny and repair. In: Adzick NS, Longaker Mt, editors. Fetal wound healing. New York: Elsevier Scientific; 1992. p. 137-47.

Longaker MT, Adzick NS, Ehrlich HP. Fetal wound contraction. In: Adzick NS, Longaker Mt, editors. Fetal wound healing. New York: Elsevier Scientific; 1992. p.149-60.

Burd DAR, Longaker MT, Adzick NS. In vitro fetal wound healing. In: Adzick NS, Longaker Mt, editors. Fetal wound healing. New York: Elsevier Scientific; 1992. p. 255-64.

Adzick NS, Longaker MT. Scarless fetal healing: therapeutic implications. In: Adzick NS, Longaker Mt, editors. Fetal wound healing. New York: Elsevier Scientific; 1992. p. 317-23.

1991

Jennings RW, Adzick NS, Harrison MR. Fetal surgery. In: Evans M, editor. Reproductive risks and prenatal diagnosis. Norwalk: Appleton and Lange; 1991. p. 311-20.

Longaker MT, Adzick NS, Harrison MR. Perioperative management of the fetus undergoing surgery in utero. In: Diaz JH, editor. Perinatal anesthesia and intensive care. Philadelphia: WB Saunders; 1991.

1990

Adzick NS. Fetal cystic adenomatoid malformation of the lung. In: Harrison MR, Golbus MS, Filly RA, editors. The unborn patient, 2nd ed. Philadelphia: WB Saunders Company; 1990. p. 557-64.

Adzick NS. Experimental pulmonary hypoplasia. In: Harrison MR, Golbus MS, Filly RA, editors. The unborn patient, 2nd ed. Philadelphia: WB Saunders Company; 1990. p. 320-7.

Langer JC, Adzick NS. Surgical management of prenatally diagnosed malformations. In: Nyberg DA, Pretorius D, editors. An ultrasound atlas of fetal malformations. Chicago: Yearbook Medical Publishers; 1990. p. 725-39.

Adzick NS, Harrison MR. Fetal surgery for congenital hydronephrosis. In: Quilligan EJ, Zuspan FP, editors. Current therapy in obstetrics and gynecology. Philadelphia: WB Saunders Co.; 1990. p. 333-38.

deLorimier AA, Harrison MR, Adzick NS. Neuroblastoma. In: Crawford ED, Das S, editors. Current genitourinary cancer surgery. Philadelphia: Lea and Febiger; 1990, p. 407-28.

deLorimier AA, Harrison MR, Adzick NS. Pediatric surgery. In: Way LW, editor. Current surgical therapy. Norwalk: Appleton-Lange; 1990. p. 1162-1206.

Longaker MT, Adzick NS, Harrison MR. An update on the status of fetal surgery. In: Nyhus LM, editor. Surgery Annual, Vol. 23. Norwalk: Appleton-Century-Crofts; 1990. p. 53-68.

1988

Flake AW, Harrison MR, Adzick NS. Intrauterine intervention: Fetal surgery. In: Brans YW, Kuehl TJ, editors. Non-human primates in perinatal research, 1st ed. John Wiley and Sons; 1988. p. 245-62.

Harrison MR, Adzick NS, Flake AW. The prenatal management of the fetus with a correctable defect. In: Callen PW, editor. Ultrasonography in obstetrics and gynecology, 2nd ed. Orlando: WB Saunders Co.; 1988. p. 364-74.

Flake AW, Adzick NS, Glick PL, Harrison MR. Evaluation of the fetus with hydronephrosis. In: White RDW, Palmer JM, editor. New techniques in urology. New York: Futura Publishing; 1987.  p. 269-85.

1987

Harrison MR, Adzick NS. Experimental correction of diaphragmatic hernia. In: Sabbagha RE, editor. Diagnostic ultrasound applied to obstetrics and gynecology, 2nd ed. Philadelphia: J.B. Lippincott Co.; 1987. p. 438-48. 

1986

Adzick NS, Harrison MR. Fetal surgery in the nonhuman primate: Experimental models for fetal treatment. In: PW Nathanielsz, editor. Animal models in fetal medicine V. Ithaca, NY: Perinatology Press; 1986. p. 153-85.

Adzick NS, Harrison MR. Surgical techniques in the fetal rabbit model. In: PW Nathanielsz, editor. Animal models in fetal medicine V. Ithaca, NY: Perinatology Press; 1986. p. 66-103.

Posters and Presentations

​2016

Adzick NS. Prenatal Management of Fetal Chest Masses. World Federation of Associations of Pediatric Surgeons (WOFAPS), 5th World Congress of Pediatric Surgery; 2016 Oct. 8; Washington, DC

Adzick NS. Fetal Surgery for Spina Bifida. World Federation of Associations of Pediatric Surgeons (WOFAPS), 5th World Congress of Pediatric Surgery; 2016 Oct. 8; Washington, DC

Adzick NS. Fetal Surgery for Myelomeningocele: Tribulations and Trials [lecture]. 8th Philadelphia Prenatal Diagnosis Conference; 2016 May 6; Philadelphia, PA.

Adzick NS. Surgical Update in the Treatment of Hyperinsulinism [lecture]. 2016 Congenital Hyperinsulinism Family Conference; 2016 Apr 16; Philadelphia, PA.

Adzick NS. Surgery for Hyperinsulinism [lecture]. Congenital Hypoglycemia Disorders: Hyperinsulinism and GSD; 2016 Apr 14; Philadelphia, PA.

Adzick NS. Is There Room for Innovative Care in the Current Business Model of Medicine and Surgery?”, “A Roadmap: The Fetal Surgery Model of Bringing Research to Innovative Clinical Care” [lecture]. 19th Annual Update on Pediatric and Congenital Cardiovascular Disease; 2016 Feb 24; Orlando, FL.

Adzick NS. Fetal Surgery for Myelomeningocele: Follow-up Results from the MOMS trial and the Post-MOMS Experience [lecture]. European Club for Fetal Surgery; 2016 Jan 20; Sils, Engadin, Switzerland.

2015

Adzick NS. Leadership Lessons from Surgery at the Children’s Hospital of Philadelphia [lecture]. CHOP Physician Leadership Program; 2015 Dec 16; Philadelphia, PA.

Adzick NS. Fetal Surgery [lecture]. Farrokh Shahnvar Lecture, Mt. Sinai Hospital; 2015 Dec 10; New York, NY.

Adzick NS. A Womb with a View: The Story of Fetal Surgery [lecture]. Speaker Series, Merion Cricket Club; 2015 Nov 19; Philadelphia, PA.

Adzick NS. A Womb with a View: The Story of Fetal Surgery [lecture]. Speaker Series, Merion Cricket Club; 2015 Oct 7; Philadelphia, PA.

Adzick NS. Fetal Surgery for Myelomeningocele: Tribulations and Trials [lecture]. Advances in Fetal Therapy, University Hospitals MacDonald Women’s Hospital; 2015 Oct 3; Cleveland, OH.

Adzick NS. Fetal Surgery. Embryology Course [lecture]. Perelman School of Medicine at the University of Pennsylvania; 2015 Sep 3; Philadelphia, PA.

Adzick NS. Fetal Surgery for Spina Bifida [lecture]. International Fetal Medicine and Surgery Society; 2015 Jun 19-23; Crete, Greece.

Adzick NS.  Fetal Surgery for Lung Lesions [lecture]. International Fetal Medicine and Surgery Society; 2015 Jun 19-23; Crete, Greece.

Adzick NS.  MOMS Trial: Predictors for the Need for Ventricular Shunt Placement, and Bladder Function Assessment. [lecture]. International Fetal Medicine and Surgery Society; 2015 Jun 19-23; Crete, Greece.

Adzick NS. Fetal Surgery Scorecard: 1995 vs 2015 [lecture]. International Update on Prenatal Diagnosis and Treatment of Fetal Anomalies; 2015 May 14-16; Union League, Philadelphia, PA.

Adzick NS. Prenatal Repair of Myelomeningocele [lecture]. International Update on Prenatal Diagnosis and Treatment of Fetal Anomalies; 2015 May 14-16; Union League, Philadelphia, PA.

Adzick NS. Fetal Surgery [lecture]. Samuel D. Gross Prize Lecture, Philadelphia Academy of Surgery; 2015 Mar 2; Philadelphia, PA.

Adzick NS. A View from the Mountain Top: Alpine Perspectives on the 4th Decade of Fetal Surgery [lecture]. European Club for Fetal Surgery; 2015 Jan 14; Engadin, Switzerland.

2014

Adzick NS. Fetal Surgery: Past, Present, Future [lecture]. Liebe Diamond Lecture; 2015 Nov 25; Sinai Hospital, Baltimore, MD.

Adzick NS. Surgery for Graves’ Disease in Children [lecture]. Graves’ Disease and Thyroid Foundation Conference, Children’s Hospital of Philadelphia; 2014 Nov 22; Philadelphia, PA.

Adzick NS. Fetal Surgery: Past, Present, Future [lecture]. OB-GYN Grand Rounds, Mt. Sinai Hospital; 2014 Oct 29; New York, NY.

Adzick NS. Fetal Surgery [lecture]. Keynote Speaker, Dale Brown Symposium, Texas Children’s Hospital; 2014 Oct 25; Houston, TX.

Adzick NS. Fetal Surgery: Past, Present, Future [lecture]. Radiology Grand Rounds, Hospital of the University of Pennsylvania; 2014 Oct 21; Philadelphia, PA.

Adzick NS. Fetal Surgery: Tribulations and Trials [lecture]. Fetology Course, Cincinnati Children’s Hospital; 2014 Sep 27; Cincinnati, OH.

Adzick NS. Fetal Surgery for Myelomeningocele: Tribulations and Trials [lecture]. Current Trends in Fetal Therapy; 2014 Sep 22; Chicago, IL.

Adzick NS. Introduction: Fetal Myelomeningocele Repair [lecture]. International Fetal Medicine and Surgery Society Meeting; 2014 Sep 9; Chatham, MA.

Adzick NS. Fetal Myelomeningocele Repair: The Post-MOMS Experience at the Children’s Hospital of Philadelphia [lecture]. International Fetal Medicine and Surgery Society Meeting; 2014 Sep 9; Chatham, MA.

Adzick NS. Fetal Surgery [lecture]. Embryology Course, Perelman School of Medicine at the University of Pennsylvania; 2014 Sep 3; Philadelphia, PA.

Adzick NS. A Womb with a View: From Philadelphia to Florence [lecture].Opening Lecture, XXIV European Congress of Perinatal Medicine; 2014 Jun 4; Florence, Italy.

Adzick NS. Fetal Surgery for Lung Lesions [lecture]. The Society for Pediatric Radiology; 2014 May 16; Washington, DC.

Adzick NS. Update on Fetal Surgery [lecture]. 34th Leading Edge in Diagnostic Ultrasound Annual Conference; 2014 May 15; Atlantic City, NJ.

Adzick NS. Prospects for Fetal Surgery [lecture]. Keynote Speaker, Surgical Research Day, Texas Children’s Hospital; 2014 May 9; Houston, TX.

Adzick NS. Featured speaker, 58th Annual Daisy Day Luncheon benefiting the Center for Fetal Diagnosis and Treatment, Bellevue Hotel; 2014 May 8; Philadelphia, PA.

Adzick NS. Fetal Surgery: Tribulations and Trials [lecture]. Society of Black Academic Surgeons State-of-the-Art Lecture; 2014 Apr 26; Philadelphia, P.

Adzick NS. Philadelphia: A Rich Source of Major Advances in Pediatric Surgery – The CHOP Experience [lecture]. Philadelphia Academy of Surgery; 2014 Mar 17; Philadelphia, PA.

Invited Lectures

2016

“Fetal Surgery for Myelomeningocele: Tribulations and Trials”.  8th Philadelphia Prenatal Diagnosis Conference, Philadelphia, PA, May 6, 2016.

“Surgical Update in the Treatment of Hyperinsulinism”. 2016 Congenital Hyperinsulinism Family Conference.  Philadelphia, PA, April 16, 2016.

“Surgery for Hyperinsulinism”. Congenital Hypoglycemia Disorders: Hyperinsulinism and GSD. Philadelphia, PA, April 14, 2016.

“Is There Room for Innovative Care in the Current Business Model of Medicine and Surgery?”, “A Roadmap: The Fetal Surgery Model of Bringing Research to Innovative Clinical Care”. 19th Annual Update on Pediatric and Congenital Cardiovascular Disease. Orlando, FL, February 24, 2016.

“Fetal Surgery for Myelomeningocele: Follow-up Results from the MOMS trial and the Post-MOMS Experience”, European Club for Fetal Surgery, Sils, Engadin, Switzerland, January 20, 2016.

2015

“Leadership Lessons from Surgery at the Children’s Hospital of Philadelphia”. CHOP Physician Leadership Program, Philadelphia, PA, December 16, 2015.

“Fetal Surgery”. Farrokh Shahnvar Lecture, Mt. Sinai Hospital, New York, NY, December 10, 2015.

“A Womb with a View: The Story of Fetal Surgery”, Speaker Series, Merion Cricket Club, Philadelphia, PA, November 19, 2015.

“Fetal Surgery: Tribulations and Trials”.  2015 American College of Surgeons John J. Conley Ethics and Philosophy Lecture, Chicago, IL, October 7, 2015.

“Fetal Surgery for Myelomeningocele: Tribulations and Trials”.  Advances in Fetal Therapy, University Hospitals MacDonald Women’s Hospital, Cleveland, OH, October 3, 2015.

“Fetal Surgery”. Embryology Course, Perelman School of Medicine at the University of Pennsylvania, September 3, 2015.

“Fetal Surgery for Spina Bifida”, “Fetal Surgery for Lung Lesions”, “MOMS Trial: Predictors for the Need for Ventricular Shunt Placement, and Bladder Function Assessment”.  International Fetal Medicine and Surgery Society, Crete, Greece, June 19-23, 2015.

“Fetal Surgery Scorecard: 1995 vs 2015”, and “Prenatal Repair of Myelomeningocele”, International Update on Prenatal Diagnosis and Treatment of Fetal Anomalies, Union League, Philadelphia, PA, March 2, 2015.

“A View from the Mountain Top: Alpine Perspectives on the 4th Decade of Fetal Surgery”, European Club for Fetal Surgery, Engadin, Switzerland, January 14, 2015.

2014

“Fetal Surgery: Past, Present, Future”. Liebe Diamond Lecture, Sinai Hospital, Baltimore, MD, November 25, 2014.

“Surgery for Graves’ Disease in Children”. Graves’ Disease and Thyroid Foundation Conference, Children’s Hospital of Philadelphia, Philadelphia, PA, November 22, 2014.

“Fetal Surgery: Past, Present, Future”. OB-GYN Grand Rounds, Mt. Sinai Hospital, New York, New York, October 29, 2014.

“Fetal Surgery”, Keynote Speaker, Dale Brown Symposium, Texas Children’s Hospital, Houston, Texas, October 25, 2014.

“Fetal Surgery: Past, Present, Future”. Radiology Grand Rounds, Hospital of the University of Pennsylvania, Philadelphia, PA, October 21, 2014.

“Fetal Surgery: Tribulations and Trials”, Fetology Course, Cincinnati Children’s Hospital, Cincinnati, OH, September 27, 2014.

“Fetal Surgery for Myelomeningocele: Tribulations and Trials”, Current Trends in Fetal Therapy, Chicago, IL, September 22, 2014.

“Introduction: Fetal Myelomeningocele Repair”, “Fetal Myelomeningocele Repair: The Post-MOMS Experience at the Children’s Hospital of Philadelphia”.  International Fetal Medicine and Surgery Society Meeting, Chatham, MA, September 9, 2014.

“Fetal Surgery”. Embryology Course, Perelman School of Medicine at the University of Pennsylvania, September 3, 2014.

“A Womb with a View: From Philadelphia to Florence”, Opening Lecture, XXIV European Congress of Perinatal Medicine, Florence, Italy, June 4, 2014.

“Fetal Surgery for Lung Lesions”, “Fetal Surgery for Myelomeningocele”, The Society for Pediatric Radiology, Washington, DC, May 16, 2014.

“Update on Fetal Surgery”, 34th Leading Edge in Diagnostic Ultrasound Annual Conference, Atlantic City, NJ, May 15, 2014.

“Prospects for Fetal Surgery”, Keynote Speaker, Surgical Research Day, Texas Children’s Hospital, Houston, Texas, May 9, 2014.

Featured speaker, 58th Annual Daisy Day Luncheon benefiting the Center for Fetal Diagnosis and Treatment, Bellevue Hotel, Philadelphia, PA, May 8, 2014.

“Fetal Surgery: Tribulations and Trials”, Society of Black Academic Surgeons State-of-the-Art Lecture, Philadelphia, PA, April 26, 2014.

“Philadelphia: A Rich Source of Major Advances in Pediatric Surgery – The CHOP Experience”, Philadelphia Academy of Surgery, Philadelphia, PA, March 17, 2014.

2013

“Fetal Surgery: Past, Present, Future”. Pediatric Grand Rounds, “Surgical Treatment of Congenital Hyperinsulinism at the Children’s Hospital of Philadelphia”, Pediatrics Resident’s Conference, St. Peter’s Hospital, New Brunswick, NJ, December 12, 2013.

“Prospects for Fetal Surgery”, Neonatal Update 2013: The Science of Newborn Care, Imperial College, London, England , November 28, 2013.

“Fetal Surgery”, Hospital for Sick Children, Great Ormond Street, London, UK, November 27, 2013.

“Fetal Surgery”, John Scott Medal Lecture. Benjamin Franklin Hall, American Philosophical Society, Philadelphia, PA, November 22, 2013.

“Spina Bifida: Fetal Surgery”, Advances in Fetal Diagnosis and Treatment, Children’s Hospital of Philadelphia, Philadelphia, PA, November 16, 2013.

“Fetal Surgery for Spina Bifida: An Update”, Surgical Grand Rounds, Children’s Hospital of Philadelphia, Philadelphia, PA, October 31, 2013.

“Surgery for Congenital Hyperinsulinism”, 4th World Congress of Pediatric Surgery, Berlin, Germany, October 15, 2013.

“Fetal Surgery for Spina Bifida: Trials and Tribulations”, Scientific Symposium, Department of Surgery, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, October 11, 2013.

“Fetal Surgery”. Embryology Course, Perelman School of Medicine at the University of Pennsylvania, September 10, 2013.

“Fetal Surgery Experience at the Children’s Hospital of Philadelphia”, Inova Fairfax Hospital OB-GYN Grand Rounds, Fairfax, VA, June 24, 2013.

“Surgery for Congenital Hyperinsulinism”, Nurse’s Education Day, Children’s Hospital of Philadelphia, May 15, 2013.

“Fetal Myelomeningocele: Life after the MOMS trial”. American Pediatric Surgery Association Meeting, Marco Island, FL, May 1, 2013.

“Fetal Surgery Experience at the Children’s Hospital of Philadelphia”, “The Tribulations and Trials of Fetal Surgery for Spina Bifida”, Northside Hospital, Atlanta, Georgia, April 17, 2013.

“Surgery Before Birth: It’s Not Science Fiction”, Advances in Pediatric Medicine, New York, NY, April 11, 2013.

“Fetal Surgery Experience at the Children’s Hospital of Philadelphia”, Winnie Palmer Hospital for Women and Babies, Orlando, FL, March 1, 2013.

“The Story of Fetal Surgery: A Womb with a View”, Speaker Series, Corinthian Yacht Club, Philadelphia, PA, February 23, 2013.

2012

“Fetal Surgery for Myelomeningocele”, Virtual World Symposium on Fetal Surgery, Akron Children’s Hospital, Akron, OH, November 20, 2012.

“Fetal Surgery for Spina Bifida: Tribulations and Trials”, American Philosophical Society, Philadelphia, PA, November 10, 2012.

“Fetal Surgery for Spina Bifida”.  Inaugural Surgical Grand Rounds, Nemours Children’s Hospital, Orlando, FL, October 17, 2012.

“Fetal Surgery for Myelomeningocele: Trials and Tribulations”, Charles Hunter Prize Lecture, American Gynecological and Obstetrical Society, Washington, DC, September 13, 2012.

“Fetal Surgery”.  Embryology Course, University of Pennsylvania School of Medicine, August 30, 2012.

“Beyond feasibility studies: The MOMS trial and thoughts on the responsible introduction of new technologies to widespread clinical practice”, American Pediatric Surgery Association Meeting, San Antonio, TX, May 20, 2012.

“Fetal Surgery: Past, Present, and Future”, Ob-Gyn Grand Rounds; “Fetal Surgery for Spina Bifida”; Surgery Grand Rounds;  Cohen Children’s Hospital and Long Island Jewish Medical Center, Long Island, NY, May 9-10, 2012.

“Fetal Surgery for Myelomeningocele One Year After the MOMS Trial Was Stopped”; Surgical Grand Rounds, Children’s Hospital of Philadelphia, Philadelphia, PA, April 26, 2012.

“Fetal Surgery”, Surgery Grand Rounds; “Fetal Surgery for Myelomeningocele: The MOMS Trial”; Pediatric Grand Rounds; Children’s Hospital of Wisconsin, Milwaukee, WI, April 25, 2012.

“The Earlier, the Better: Treating Families Before Birth and Beyond”, Advances in Pediatric Medicine, New York, NY, April 17, 2012.

“Fetal Surgery for Spina Bifida: Trials and Tribulations”, Surgeons Travel Club, Union League, Philadelphia, PA, April 13, 2012.

“Surgery for Congenital Hyperinsulinism”, Fourth Congenital Hyperinsulinism Family Conference, Philadelphia, PA, March 17, 2012.

“Surgery for Congenital Hyperinsulinism”, Monogenic Disorders of Insulin Secretion: Congenital Hyperinsulinism and Neonatal Diabetes. Philadelphia, PA, March 15, 2012.

“Fetal Myelomeningocele Repair: The MOMS Trial”, 2nd World Congress on Spina Bifida Research, Las Vegas, Nevada, March 13, 2012.

“A Baby with Hypoglycemia”, Surgical Grand Rounds, Children’s Hospital of Philadelphia, Philadelphia, PA, March 8, 2012.

“The Birth of a Breakthrough”, Pediatrics Grand Rounds, Children’s Hospital of Philadelphia, Philadelphia, PA, February 22, 2012.

“Fetal Surgery for Spina Bifida: Trials and Tribulations”, Obstetrics and Gynecology Grand Rounds, Pennsylvania Hospital, Philadelphia, PA, January 18, 2012.

2011

“Fetal Surgery”, CHOP Faculty Luncheon Speaker Series, Philadelphia, PA, December 9, 2011.

“Prenatal Surgery for Spina Bifida-MOMS Trial”, Hot Topics in Neonatology, Washington, D.C., December 5, 2011.

“Fetal Surgery: Then, Now, Next”, 10th World Congress of Perinatal Medicine, Punta del Este, Uruguay., November 9, 2011.

“A Breakthrough in Fetal Surgery: The MOMS Trial – An Overview”, Advances in Neonatology, Children’s Hospital of Philadelphia, October 27, 2011.

“Fetal Surgery for Spina Bifida: The Birth of a Breakthrough”, Jewish Federation of Greater Philadelphia, Philadelphia, PA, October 24, 2011.

“Fetal Surgery for Spina Bifida: Trials and Tribulations”, Joint Surgery - Anesthesia Grand Rounds, Boston Children’s Hospital, Boston, MA, September 28, 2011.

“Fetal Surgery”, Massachusetts General Hospital Surgical Society, Boston, MA, September 10, 2011.

“Fetal Surgery.”  Embryology Course, University of Pennsylvania School of Medicine, August 31, 2011.

“Meet the Expert: Fetal Surgery”, British Association of Pediatric Surgery, Belfast, Ireland, July 22, 2011.

“Antenatal Surgery for Spina Bifida”, Isabella Forshall Lecture, British Association of Paediatric Surgeons, Belfast, Ireland, July 21, 2011.

“The MOMS Trial”, Keynote Speaker, Spina Bifida Association, National Conference, Anaheim, CA, June 27, 2011.

“The MOMS Trial: Results and Next Steps”, and “Prenatal Surgery for Myelomeningocele: Patient Selection, Technique, Care Pathway, and Lessons Learned”, 30th International Fetal Medicine and Surgery Society Meeting, Sedona, Arizona, May 16, 2011.

“Fetal Myelomeningocele Repair: The MOMS Trial”, Department of Anesthesiology and Critical Care Grand Rounds, Children’s Hospital of Philadelphia, May 12, 2011.

“Prenatal Repair of Myelomeningocele”, Philadelphia Perinatal Society, Philadelphia, PA, April 13, 2011.

“The Center for Fetal Diagnosis and Treatment: 15 Years of Innovation; a Historical Perspective”, and “Prenatal Repair of Myelomeningocele”, International Update on Prenatal Diagnosis and Treatment of Fetal Anomalies, Union League, Philadelphia, PA, March 16, 2011.

2010

“Fetal Surgery.”  Embryology Course, University of Pennsylvania School of Medicine, September 2, 2010.

“Update on Fetal Surgery”, Latest Developments in Obstetrical Management, Women’s Center at Presbyterian Hospital, Charlotte, NC, May 8, 2010.

2009

“Fetal Surgery.”  Embryology Course, University of Pennsylvania School of Medicine, September 3, 2009.

2008

"MOMS Trial Update", International Fetal Medicine and Surgery Society, Athens, Greece, September 12, 2008.

“Fetal Surgery.”  Embryology Course, University of Pennsylvania School of Medicine, September 4, 2008.

“Fetal Surgery”, “Surgical Treatment of Congenital Hyperinsulinism”, Jay Grosfeld Visiting Professor, Riley Children’s Hospital, Indianapolis, Indiana, May 14, 2008.

“Medical and Surgical Care of the Fetus”, OB-GYN Grand Rounds, Prentice Pavilion, Northwestern University Medical School, Chicago, Illinois, February 15, 2008.

“Fetal Surgery”, “Surgical Treatment of Congenital Hyperinsulinism”, Loren R. Chandler Lectures in Pediatric Surgery, Stanford University, Palo Alto, CA, February 5, 2008.

2007

“Fetal Therapy: Past, Present, and Future”. Saitama Children’s Hospital, Tokyo, Japan, October 23, 2007.

“Fetal Surgery”, “Indications for Fetal Therapy for Congenital Diaphragmatic Hernia”. 5th Annual Meeting of the Japan Society of Fetal Therapy, Osaka, Japan, October 20, 2007.

“Ethical Issues of Fetal Therapy.”  5th Annual Meeting of the Japan Society of Fetal Therapy, Osaka, Japan, October 19, 2007.

“Fetal Surgery.”  Embryology Course, University of Pennsylvania School of Medicine, September 6, 2007.

“The Care of the Fetus: Fetal Medicine and Fetal Surgery.” The Conference for the Neonate, Lake Buena Vista, FL, February 8, 2007.

2006

“State-of-the-Art Lecture: Fetal Surgery”.  British Association of Pediatric Surgery, Stockholm, Sweden, July 21, 2006.

“Surgical Management of Hyperinsulinism”. Congenital Hyperinsulinism and Related Disorders of Insulin Secretion, Philadelphia, PA, June 15, 2006.

“Fetal Intervention: What is Proven, What is Promising, What Has Failed” and “Prenatal Repair of Myelomeningocele: Is Fetal Surgery Justified for Non-Lethal Anomalies”.  American Pediatric Surgical Association, Hilton Head, South Carolina, May 21, 2006.

2005

“Fetal Surgery for Spina Bifida”, “Prenatal Diagnosis and Postnatal Management of Conjoined Twins”, “Fetal Surgery for Congenital Diaphragmatic Hernia”, “Treatment of Fetal Lung Lesions”, “Ex Utero Intrapartum Therapy”, “The Future of Fetal Therapy”.  Chilean Society of Obstetrics and Gynecology 30th Annual Meeting, Vina del Mar, Chile, November 10, 2005.

“Congenital Cystic Adenomatoid Malformation and Bronchopulmonary Sequestration: Differential Diagnosis, Prenatal and Postnatal Management”. Update on Prenatal Diagnosis and Treatment of Fetal Anomalies, Philadelphia, PA, June 10, 2005.

“Fetal Surgery for Myelomeningocele”. Update on Prenatal Diagnosis and Treatment of Fetal Anomalies, Philadelphia, PA, June 9, 2005.

“The EXIT Procedure: The CHOP Experience”. Nobel Symposium on Fetal Therapy. Stockholm, Sweden, May 21, 2005.

2004

“An Update on Fetal Surgery”.  Surgical Grand Rounds, University of Wisconsin, Madison, Wisconsin, November 10, 2004.

“Pancreatectomy for Congenital Hyperinsulinism.”  Madison Surgical Society, Madison, Wisconsin, November 9, 2004.

“An Update on Fetal Surgery”. Society of Clinical Surgery, Hospital of the University of Pennsylvania, November 4, 2004.

“The MOMS Trial: Principles, Oversight, and Lessons Learned (So Far)”. International Fetoscopy Group, Philadelphia, PA, October 3, 2004.

“Fetal Neurologic Disease: Future Directions”, NICHD Fetal Therapy Workshop, Washington, D.C., August 17, 2004.

“The MOMS Trial: Guiding Principles and Lessons Learned”. NICHD Fetal Therapy Workshop, Washington, D.C., August 16, 2004.

“MOMS Trial Update”, International Fetal Medicine and Surgery Society, Charleston, SC, March 14, 2004.

2003

“Pancreatectomy for Congenital Hyperinsulinism.”  Georgia Surgical Society, Sea Island, Georgia, November 14, 2003.

“Fetal surgery for spina bifida: Clinical trials and tribulations.”  Georgia Surgical Society, Sea Island, Georgia, November 13, 2003.

“Lessons learned from the myelomeningocele experience that can be applied to development of a fetal surgery program for congenital heart disease.”  Section on Cardiology and Cardiac Surgery, American Academy of Pediatrics, New Orleans, LA, November 1, 2003.

“Fetal Surgery: State-of-the-Art”, Pediatric Surgery Symposium, University of Padua, Padua, Italy, October 3, 2003.

“Fetal Surgery”, Fred McLeod and Journal of Pediatric Surgery Lecture, Canadian Association of Pediatric Surgery, Niagara-on-the-Lake, Ontario, Canada, September 19, 2003.

“A multidisciplinary approach to the focal form of congenital hyperinsulinism leads to successful treatment by partial pancreatectomy”, American Pediatric Surgical Association meeting, Fort Lauderdale, FL , May 27, 2003.

“Ex Utero Intrapartum Therapy (EXIT) in the Management of Fetal Chest Lesions”, International Fetal Medicine and Surgery Society, Zermatt, Switzerland, April 28, 2003.

“Human Fetal Surgery for Myelomeningocele: Update on the NIH Trial”, Mind the Gap Symposium, Zurich, Switzerland, April 25, 2003.

“Fetal Surgery for Myelomeningocele: Tribulations and Trials”, W. Hardy Hendren M.D. Festschrift, Boston Children’s Hospital, Boston, MA, April 11, 2003.

“Fetal Surgery”, Dale Johnson Honorary Lecture, Combined Departments of Surgery and Pediatrics Grand Rounds, University of Utah, Salt Lake City, Utah, January 22, 2003.

“Conjoined Twins”, Salt Lake City Surgery Society, Salt Lake City, Utah, January 21, 2003.

2002

“Fetal Surgery for Myelomeningocele”, Invited Speaker, American Society of Human Genetics, Baltimore, MD, October 16, 2002.

“Myelomeningocele Repair in Humans: The Children’s Hospital of Philadelphia Experience” and “The NIH-Sponsored Trial for Spina Bifida Repair”. Update on Fetal Diagnosis and Treatment.  Philadelphia, PA, September 27, 2002.

“Fetal Surgery”. Marjorie and Julius Kantor Educational Lecture.  Children’s Mercy Hospital, Kansas City, MO, September 12, 2002.

“Fetal Surgery: Where we are and where we are going.”  Society of Pediatric Radiology, Philadelphia, PA, May 2, 2002.

“Clinical Fetal Surgery: State-of-the-Art”.  International Pediatric Surgery Symposium, Zurich, Switzerland, April 22, 2002.

“Fetal surgery for CCAM & SCT; EXIT”, “Fetal surgery for myelomeningocele”, “Fetal surgery for congenital diaphragmatic hernia”. Workshop on Fetal Surgery, Barcelona, Spain, March 25, 2002.

“Evolution and spectrum of fetal interventions”, Society of Pediatric Anesthesia, Miami, FL, March 10, 2002.

2001

“Fetal Surgery”, Surgical Grand Rounds, Texas Children’s Hospital, Houston, TX, April 12, 2001.

“Fetal Surgery: State of the Art”, Surgical Grand Rounds, Hospital of the University of Pennsylvania, March 15, 2001.

2000

“Fetal Surgery: State of the Art”, Invited Lecturer, XVII Congress of Asian Association of Pediatric Surgeons, Fukuoka, Japan, November 9, 2000.

“Advances in Fetal Surgery”, Invited Lecturer, Perinatal Section, American Academy of Pediatrics, Chicago, IL, October 25, 2000.

“Fetal Surgery for Myelomeningocele”, NIH Symposium on Fetal Surgery, Bethesda, MD, July 17, 2000.

1999

“Lung Defects and Diaphragmatic Hernia – Prenatal Surgery”, Diploma in Fetal Medicine Course, King’s College Hospital, London, England, September 6, 1999.

“A Womb with a View”, MGH Surgical Alumni Reunion. Boston, MA, June 17, 1999.

“Minimally Invasive Fetal Therapy”, CIMIT Invited lecture, Massachusetts General Hospital, Boston, MA, April 20, 1999.

“Fetal Therapy in the 21st Century”. Hospital St. Justine, Hospital Grand Rounds, Montreal, Canada, January 20, 1999.

“Fetal Wound Healing”. University of Montreal, Department of Surgery Grand Rounds, Montreal, Canada, January 20, 1999.

“An Update on Open Fetal Surgery”. 7Th Annual Perinatal Ultrasound Symposium, UMDNJ, New Brunswick, NJ, January 17, 1999.

1998

“Fetal Therapy”.  Ob-Gyn Grand Rounds,  Mt.Sinai – NYU Medical Center, New York, NY, December 9, 1998.

“Fetal Surgery – New Frontier”. Pediatric Travel Club, Philadelphia, PA, September 12, 1998.

“Prenatal Therapy”. Keynote speaker, The Institute for the Unborn Baby, Chicago, IL, June 26, 1998.

“The Unborn Surgical Patient”. 50th Simpson Smith Memorial Lecture, Institute of Child Health and Great Ormond Street Hospital, London, England, June 4, 1998.

“Fetal Surgery: Past, Present, and Future”. Galaxy of Stars, Maternal-Fetal Medicine Course, Sydney, Australia, May 9, 1998.

“New Patients – Fetal Therapy”. Royal Australasian College of Surgeons Congress, Sydney, Australia, May 5, 1998.

“Fetal Intervention”. Royal Women’s Hospital and Sydney Children’s Hospital, Sydney, Australia, May 4, 1998.

“Strategies to Enhance Fetal Lung Growth”. Department of Physiology, Monash University, Melbourne, Australia, May 2, 1998.

“The Diaphragmatic Hernia Story”, “Experience with the EXIT Procedure”, “Fetal Therapy – 1998”. Division of Pediatric Surgery, Christchurch Hospital, Christchurch, New Zealand, April 29, 1998.

“Fetal Therapy”. Department of Ob-Gyn, St. Peter’s Hospital, Robert Wood Johnson School of Medicine, New Brunswick, NJ, March 18, 1998.

“Fetal Therapy”. Visiting Professor, Department of Surgery, University of Michigan, Ann Arbor, Michigan, March 5, 1998.

“Fetal Surgery 1998: When is it indicated, who is a candidate, where should     it be done”.  Society of Perinatal Obstetricians, Miami, Florida, February 5, 1998.

Awards and Honors

2016, Pennsylvania Bio Patient Impact Award

2015, Samuel D. Gross Prize, to be given every five years for the most significant advance in surgery by an American citizen

2013, John Scott Legacy Medal and Premium. Created in 1816, it is a medal presented to men and women whose inventions and innovations improved the “comfort, welfare, and happiness of human kind” in a significant way. Previous recipients include Thomas Edison, Madame Curie, the Wright Brothers, Nicola Tesla, Edwin Land, Jonas Salk, Frederick Banting, Guglielmo Marconi, Alexander Fleming, and many Nobel Laureates. 

2012, Pediatric Hero, Babytalk Magazine



2012,  Clayton High School Alumni Hall of Fame



2012, Charles Hunter Prize, American Gynecological and Obstetrical Society



2012, Honorary Member, American Gynecological and Obstetrical Society



2012, Clinical Trial of the Year, Society for Clinical Trials, Management of Myelomeningocele Study

2011-15, President-at-Large, International Fetal Medicine and Surgery Society

2011, Community Service Award, Chai Lifeline

2011, Audrey Evans Award of Excellence, Ronald McDonald House

2005, Honorary Member, Chilean Society of Obstetrics and Gynecology

2005, Nobel Forum Lecturer, Karolinska Institute, Stockholm

2003, Honorary Member, Canadian Association of Pediatric Surgery

2003, Fellow, American Association for the Advancement of Science

2002, Elected into the “International Order of the Smile”

2001, “Person of the Year”, Southeastern Pennsylvania Chapter of the March of Dimes

2000, President, International Fetal Medicine and Surgery Society

1999, Presidential Cross for Contributions to the Republic of Poland

1998, Australia and New Zealand Chapter of the American College of Surgeons Traveling Fellowship

1998, Institute of Medicine, National Academy of Sciences

1996, University of Penn Med Student Teaching Award

1995, Honorary Masters of Arts Degree, University of Penn

1993, 1995, UCSF Surgical Residents' Teaching Award

1992, Honorary Award, American Association of Plastic Surgeons

1990-95, Focused Giving Award, Johnson and Johnson

1990-92, National Kidney Foundation Fellowship

1989-90, American Lung Association Research Award

1986-87, Schering Scholarship, American College of Surgeons

1984, First Place, Young Investigators Award, Surgical Section, AAP

1983-85, National Research Service Award, National Institute of Health

1983-84, Marshall K. Bartlett Fellowship, Massachusetts General Hospital

1983-85, American College of Surgeons Scholarship

1979,  Richard C. Cabot Prize, Harvard Medical School

1975,  Phi Beta Kappa

1975,  Harvard National Scholar

Editorial and Academic Positions

Editorial positions
Editorial board

2000-present, Current Problems in Surgery
1997-present, Fetal Diagnosis and Therapy
1993-present, Journal of Pediatric Surgery
1993-present, Annals of Surgery

Academic and Institutional Committees

2015-present, Scientific Advisory Committee, Sheikh Zayed Institute for Pediatric Surgery Innovation; 2017, Chairman
2012-present, Medical Advisory Board, CHERUBS
1998-present, 
Children’s Hospital of Philadelphia Practice Association Board of Directors
 - 2016-2019, Vice-President

1995-present, Board of Trustees, The Children’s Hospital of Philadelphia
 
- Finance Committee
 
- Healthcare Status Committee
 
- Executive Committee
1995-present, Executive Committee of the Medical Staff
1995-present, Chairman, Operating Room Committee

Leadership and Memberships

International Societies

British Association of Paediatric Surgery

Canadian Association of Pediatric Surgery (honorary member)

Chilean Society of Obstetrics and Gynecology (honorary member)

European Club for Fetal Surgery

International Fetal Medicine and Surgery Society

North American Fetal Therapy Network (Founding Member;Executive Committee, 2003-10)

Pacific Association of Pediatric Surgeons

Society of Laparoendoscopic Surgeons

Wound Healing Society

National Societies

American Academy of Pediatrics, Surgical Section

American Association for the Advancement of Science

American Association for Physician Leadership

American College of Surgeons, Fellow

American Gynecological and Obstetrical Society, honorary member

American Pediatric Surgical Association

- Chairman 2014-2017

American Surgical Association

Association for Academic Surgery

Association of Pediatric Surgery Training Program Directors

Childrens Cancer Study Group

Institute of Medicine (now National Academy of Medicine)

National Academy of Sciences

March of Dimes

MGH Surgical Alumni Society

Organization of Children’s Hospitals Surgeons-in-Chief

Society of Critical Care Medicine

Society of University Surgeons