Education and Training
DO - University of Medicine and Dentistry of New Jersey, School of Osteopathic Medicine, Stratford, NJ
Pediatrics - Schneider Children's Hospital at North Shore Long Island Jewish, New Hyde Park, NY
Pediatric Pulmonary and Sleep Medicine - Children's Hospital of Philadelphia, Philadelphia, PA
Pediatric Pulmonology – American Board of PediatricsPediatrics – American Board of Pediatrics
AmeriSpan SALUD Medical Spanish Program, Salamanca, Spain
BLS, PALS, NRP Certified
Titles and Academic Titles
Medical Director of the Lung and Heart/Lung Transplant Programs
Assistant Professor of Clinical Pediatrics, Perelman School of Medicine at the University of Pennsylvania
Departments and Services
Dean T, McDonough JM, Josephson M, Ginsberg JP, Carlson CA, Fiorino EK, Goldfarb SB.: Thoracic growth deficiency in childhood cancer survivors may cause overestimation of lung disease. Pediatric Pulmonology 54(10): 1602-1609, October 2019.
Hu A, Diener BL, Josephson MB, Grunstein MM: Constitutively active signaling by the G protein βγ-subunit mediates intrinsically increased phosphodiesterase-4 activity in human asthmatic airway smooth muscle cells. Plos One 10(3): e0118712, March 2015 Notes: http://dx.doi.org/ 10.1371/journal.pone.0118712
Hu Aihua, Josephson Maureen B, Diener Barry L, Nino Gustavo, Xu Shuyun, Paranjape Chinmay, Orange Jordan S, Grunstein Michael M: Pro-asthmatic cytokines regulate unliganded and ligand-dependent glucocorticoid receptor signaling in airway smooth muscle. PloS one 8(4): e60452, 2013. PMCID: PMC3617099
Josephson Maureen B, Jiao Junfang, Xu Shuyun, Hu Aihua, Paranjape Chinmay, Grunstein Judith S, Grumbach Yael, Nino Gustavo, Kreiger Portia A, McDonough Joseph, Grunstein Michael M: IL-13-induced changes in endogenous glucocorticoid metabolism in the lung regulate the proasthmatic response. American journal of physiology. Lung cellular and molecular physiology 303(5): L382-90, Sep 2012. PMCID: PMC3468426
Nino Gustavo, Hu Aihua, Grunstein Judith S, McDonough Joseph, Kreiger Portia A, Josephson Maureen B, Choi John K, Grunstein Michael M: G Protein βγ-subunit signaling mediates airway hyperresponsiveness and inflammation in allergic asthma. PloS one 7(2): e32078, 2012. PMCID: PMC3284547
Dean T, Josephson M, Goldfarb S. Thoracic Growth Deficiency in Childhood Cancer Survivors: Are We Overestimating Restrictive Lung Disease? American Thoracic Society 2015.
A. Hu, B.L. Diener, M.B. Josephson, M.M. Grunstein: Pro-Asthmatic Signaling via the G Protein beta gamma Subunit is Intrinsically Activated in Cultured Human Asthmatic Airway Smooth Muscle Cells. American Thoracic Society 2013 Notes: Poster Discussion Session at the American Thoracic Society, Philadelphia, May 2013.
B.L. Diener, A. Hu, M.B. Josephson, M.M. Grunstein: Differential Effects of IL-13 on Serine Site-Specific Glucocorticoid Receptor (GR) Phosphorylation in Human Airway Smooth Muscle (HASM) Cells. American Thoracic Society 2013 Notes: Poster Discussion Session at the American Thoracic Society, Philadelphia, May 2013.
M. B. Josephson, A. Hu, B. L. Diener, and M. M. Grunstein: Phosphodiesterase 4 (PDE4) Activity is Intrinsically Increased in Cultured Human Asthmatic Airway Smooth Muscle Cells Due to Upregulated G protein βγ-subunit Activation. American Thoracic Society 2013 Notes: Accepted as an oral presentation in a Mini-Symposium at the American Thoracic Society, Philadelphia, May 2013.
A. Hu, PhD, M.B. Josephson, D.O., S. Xu, M.D., G. Nino, MD, J.S. Grunstein, M.A., M.M. Grunstein, M.D. Ph.D. : Regulation Of Glucocorticoid Receptor (GR) Phosphorylation And Transcriptional Signaling By IL-13 In Human Airway Smooth Muscle (HASM) Cells. American Thoracic Society 2012.
G. Nino, MD, A. Hu, PhD, J.S. Grunstein, MA, M.B. Josephson, D.O., C.S. Paranjape, B.S., M.M. Grunstein, MD, PhD.: Glucocorticosteroids Prevent The Pro-Asthmatic Effects Of IgE On Airway Smooth Muscle (ASM) Function By Inhibiting Phosphodiesterase 4 (PDE4) Activity. American Thoracic Society 2012.
M. B. Josephson, S. Goldfarb: Plastic Bronchitis: An Unusual Cause For Atelectasis In A Patient With Prune Belly Syndrome. American Thoracic Society 2012.
M.B. Josephson, S. Xu, G. Nino, A. Hu, J.S. Grunstein, M.M. Grunstein: Expression And Activity Of The Endogenous Glucocorticoid (GC)-Activating Enzyme, 11β-Hydroxysteroid Dehydrogenase-1 (HSD-1), Are Suppressed In Asthmatic Airway Smooth Muscle Cells. American Thoracic Society 2012 Notes: Poster Discussion Session at the American Thoracic Society Meeting, San Francisco, May 2012.
Cassandra Aravelo and Maureen Banfe Josephson: Book Title: Diagnostic and Interventional Bronchoscopy in ChildrenChapter Title: Flexible Bronchoscopy and Children's Interstitial Lung Disease. Respiratory Medicine. Springer Nature Switzerland, 2020.
Ambika G. Chidambaram Maureen Josephson: Clinical research study designs: The essentials. Pediatric Investigation 3(4): 245-252, December 2019.
Shapiro AJ, Davis SD, Polineni D, Manion M, Rosenfeld M, Dell SD, Chilvers MA, Ferkol TW, Zariwala MA, Sagel SD, Josephson M, Morgan L, Yilmaz O, Olivier KN, Milla C, Pittman JE, Daniels MLA, Jones MH, Janahi IA, Ware SM, Daniel SJ, Cooper ML, Nogee LM, Anton B, Eastvold T, Ehrne L, Guadagno E, Knowles MR, Leigh MW, Lavergne V; American Thoracic Society Assembly on Pediatrics.: Diagnosis of Primary Ciliary Dyskinesia. An Official American Thoracic Society Clinical Practice Guideline. American Journal of Respiratory and Critical Care Medicine 197(1): e24- e39, June 2018.
Josephson M, Benden C, Hanna B: Solid Organ Transplantation in Infants and Children: Indications for lung transplantation. Organ and Tissue Transplantation Book Series Springer, 2018 Notes: Book chapter.
Shapiro A, Josephson M, Rosenfeld M, Yilmaz O, Davis S, Polineni D, Guadagno E, Leigh M, Lavergne V: Accuracy of nasal nitric oxide as a diagnostic test for primary ciliary dyskinesia: A systematic review and metaanalysis. Annals of the American Thoracic Society 14(7): 1184-1196, July 2017.
Goldfarb SB, Josephson M. Cystic Fibrosis. BMJ Best Practice 2015.
Goldfarb SB, Josephson M. Cystic Fibrosis. BMJ Point-of-Care 2015.
Posters and Presentations
Lectures by Invitation
"Pulmonary Aspects of Cystic Fibrosis", The American Austrian Foundation, Salzburg, Austria
"Non-Pulmonary Aspects of Cystic Fibrosis", The American Austrian Foundation, Salzburg, Austria
"Clinical Trials- The Essentials", The American Austrian Foundation, Salzburg, Austria
"Infants/child/Lung Transplant", lecture given at Neonatology Grand Rounds at Capital Health in Hopewell NJ
Josephson MB. Community Acquired Pneumonia: When to Order What? Presented at: American Academy of Pediatrics; 2015 Oct; Washington DC.
Josephson MB. Cystic Fibrosis: An update on clinical and genetic aspects. Grandview Hospital; 2015 Oct; Sellersville PA.
Josephson MB. Interpreting genetic testing in PCD patients. PCD On the Move Clinical Conference; 2015 Aug; Minneapolis MN.
Awards and Honors
2022, SJ Mag's Top Docs in Pulmonology
2011, American Thoracic Society Fellows Track Symposium, Travel Scholarship Recipient
2011, American College of Chest Physicians Pediatric Pulmonary and Critical Care Fellows Conference, Travel Scholarship Recipient
2011, Jacqueline E. Swartz Endowed Fellowship in Pediatric Pulmonology
Editorial and Academic Positions
2016-present, Reviewer, Pediatric Transplantation
Leadership and Memberships
2016-present, International Society of Heart and Lung Transplantation (ISHLT)
2020-Present, United Network for Organ Sharing (Lung Review Board Member
2009-Present, American Thoracic Society
2009-present, American College of Chest Physicians
2006-present, American Academy of Pediatrics (AAP)
2002-present, American Osteopathic Association
Patient Experience Ratings
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