Todd Kilbaugh, MD

2025

Kirschen MP, Ullman NL, Reeder RW, Ahmed T, Bell MJ, Berg RA, Burns C, Carcillo JA, Carpenter TC, Diddle J, Federman M, Fink EL, Frazier AH, Friess SH, Graham K, Horvat CM, Huard LL, Kilbaugh TJ, Maa T, Manga A, McQuillen PS, Meert KL, Morgan RW, Mourani PM, Nadkarni VM, Naim MY, Notterman D, Palmer CA, Pollack MM, Sapru A, Sharron MP, Srivastava N, Tilford B, Viteri S, Wolfe HA, Yates AR, Topjian A, Sutton RM, Press CA: Practice patterns for acquiring neuroimaging after pediatric in-hospital cardiac arrest. Resuscitation 207: 110506, January 2025.

Zuckerberg JC, Ko T, Weeks MK, Widmann NJ, Kienzle MF, Gaudio HA, Silva LE, Reeder RW, Sutton RM, Berg RA, Kilbaugh TJ, Morgan RW: Evaluation of coronary perfusion pressure and diastolic blood pressure calculation methods in a swine model of pediatric cardiopulmonary resuscitation. Resuscitation Plus 23: 100928, May 2025.

2024

Mavroudis CD, Lewis A, Greenwood JC, Kelly M, Ko TS, Forti RM, Shin SS, Shofer FS, Ehinger JK, Baker WB, Kilbaugh TJ, Jang DH.: Investigation of Cerebral Mitochondrial Injury in a Porcine Survivor Model of Carbon Monoxide Poisoning. J Med Toxicol 20(1): 39-48, January 2024. PMCID: PMC10774472

Aronowitz DI, Geoffrion TR, Piel S, Benson EJ, Morton SR, Starr J, Melchior RW, Gaudio HA, Degani RE, Widmann NJ, Weeks MK, Ko TS, Licht DJ, Hefti M, Gaynor JW, Kilbaugh TJ, Mavroudis CD: Early Impairment of Cerebral Bioenergetics After Cardiopulmonary Bypass in Neonatal Swine. World Journal for Pediatric & Congenital Heart Surgery Epub ahead of print, April 2024.

Greenwood JC, Talebi FM, Jang DH, Spelde AE, Gordon EK, Horak J, Acker MA, Kilbaugh TJ, Shofer FS, Augoustides JGT, Brenner JS, Muzykantov VR, Bakker J, Abella BS: Anaerobic Lactate Production Is Associated With Decreased Microcirculatory Blood Flow and Decreased Mitochondrial Respiration Following Cardiovascular Surgery With Cardiopulmonary Bypass. Critical Care Medicine Online ahead of print, April 2024.

Loaec M, Himebauch AS, Reeder R, Alvey JS, Race JA, Su L, Lasa JJ, Slovis JC, Raymond TT, Coleman R, Barney BJ, Kilbaugh TJ, Topjian AA, Sutton RM, Morgan RW, and the American Heart Association's Get With The Guidelines-Resuscitation Investigators: Outcomes of Extracorporeal Cardiopulmonary Resuscitation for In-Hospital Cardiac Arrest Among Children with Non-Cardiac Illness Categories. Critical Care Medicine 52(4): 551-562, April 2024.

Loaec M, Himebauch AS, Reeder R, Alvey JS, Race JA, Su L, Lasa JJ, Slovis JC, Raymond TT, Coleman R, Barney BJ, Kilbaugh TJ, Topjian AA, Sutton RM, Morgan RW; American Heart Association's (AHA) Get With The Guidelines-Resuscitation (GWTG-R) Investigators.: Outcomes of Extracorporeal Cardiopulmonary Resuscitation for In-Hospital Cardiac Arrest Among Children With Noncardiac Illness Categories. Crit Care Med 52: 551-562, Apr 2024.

Zhang Z, Hwang M, Kilbaugh TJ, Katz J: Improving sub-pixel accuracy in ultrasound localization microscopy using supervised and self-supervised deep learning. Measurement Science & Technology 35: 045701, April 2024. PMCID: PMC10774911

Aronowitz DI, Geoffrion TR, Piel S, Morton SR, Starr J, Melchior RW, Gaudio HA, Degani R, Widmann NJ, Weeks MK, Ranieri NR, Benson E, Ko TS, Licht DJ, Hefti M, Gaynor JW, Kilbaugh TJ, Mavroudis CD: Normoxic Management during Cardiopulmonary Bypass Does Not Reduce Cerebral Mitochondrial Dysfunction in Neonatal Swine. International Journal of Molecular Sciences 25(10): 5466, May 2024. PMCID: PMC11122014

Greenwood JC, Morgan RW, Abella BS, Shofer FS, Baker WB, Lewis A, Ko TS, Forti RM, Yodh AG, Kao SH, Shin SS, Kilbaugh TJ, Jang DH: Carbon monoxide as a cellular protective agent in a swine model of cardiac arrest protocol. PloS One 19(5): e0302653, May 2024. PMCID: PMC11095756

Greenwood JC, Morgan RW, Abella BS, Shofer FS, Baker WB, Lewis A, Ko TS, Forti RM, Yodh AG, Kao SH, Shin SS, Kilbaugh TJ, Jang DH.: Carbon monoxide as a cellular protective agent in a swine model of cardiac arrest protocol. PLoS One 19: e0302653, May 2024. PMCID: PMC11095756

Piel S, McManus MJ, Heye KN, Beaulieu F, Fazelinia H, Janowska JI, MacTurk B, Starr J, Gaudio H, Patel N, Hefti MM, Smalley ME, Hook JN, Kohli NV, Bruton J, Hallowell T, Delso N, Roberts A, Lin Y, Ehinger JK, Karlsson M, Berg RA, Morgan RW, Kilbaugh TJ: Effect of dimethyl fumarate on mitochondrial metabolism in a pediatric porcine model of asphyxia-induced in-hospital cardiac arrest. Scientific Reports 14(1): 13852, June 2024. PMCID: PMC11180202

Smood B, Katsunari T, Smith C, Dori Y, Mavroudis CD, Morton S, Davis A, Chen JM, Gaynor JW, Kilbaugh T, Maeda K: Preliminary report of a thoracic duct-to-pulmonary vein lymphovenous anastomosis in swine: A novel technique and potential treatment for lymphatic failure. Seminars in Pediatric Surgery 33(3): 151427, June 2024.

Guarnieri JW, Lie T, Albrecht YES, Hewin P, Jurado KA, Widjaja GA, Zhu Y,McManus MJ, Kilbaugh TJ, Keith K, Potluri P, Taylor D, Angelin A, Murdock DG,Wallace DC: Mitochondrial antioxidants abate SARS-COV-2 pathology in mice. Proc Natl Acad Sci U S A 121(30): e2321972121, July 2024. PMCID: PMC11287122

O'Halloran AJ, Reeder RW, Berg RA, Ahmed T, Bell MJ, Bishop R, Bochkoris M, Burns C, Carcillo JA, Carpenter TC, Dean JM, Diddle JW, Federman M, Fernandez R, Fink EL, Franzon D, Frazier AH, Friess SH, Graham K, Hall M, Hehir DA, Horvat CM, Huard LL, Kienzle MF, Kilbaugh TJ, Maa T, Manga A, McQuillen PS, Meert KL, Mourani PM, Nadkarni VM, Naim MY, Notterman D, Pollack MM, Sapru A, Schneiter C, Sharron MP, Srivastava N, Tilford B, Topjian AA, Viteri S, Wessel D, Wolfe HA, Yates AR, Zuppa AF, Sutton RM, Morgan RW: Early bolus epinephrine administration during pediatric cardiopulmonary resuscitation for bradycardia with poor perfusion: an ICU-resuscitation study. Crit Care 28(1): 242, July 2024. PMCID: PMC11251231

Senthil K, Ranganathan A, Piel S, Hefti MM, Reeder RW, Kirschen MP, Starr J, Morton S, Gaudio HA, Slovis JC, Herrmann JR, Berg RA, Kilbaugh TJ, Morgan RW: Elevated serum neurologic biomarker profiles after cardiac arrest in a porcine model. Resuscitation Plus 19, September 2024. PMCID: PMC11325790

Silva LEV, Gaudio HA, Widmann NJ, Forti RM, Padmanabhan V, Senthil K, Slovis JC, Mavroudis CD, Lin Y, Shi L, Baker WB, Morgan RW, Kilbaugh TJ, Tsui FR, Ko TS: Amplitude spectrum area is dependent on the electrocardiogram magnitude: evaluation of different normalization approaches. Physiological Measurement 45(11), November 2024.

Gaudio HA, Padmanabhan V, Landis WP, Silva LEV, Slovis J, Starr J, Weeks MK, Widmann NJ, Forti RM, Laurent GH, Ranieri NR, Mi F, Degani RE, Hallowell T, Delso N, Calkins H, Dobrzynski C, Haddad S, Kao SH, Hwang M, Shi L, Baker WB, Tsui F, Morgan RW, Kilbaugh TJ, Ko TS: A novel translational bioinformatics framework for facilitating multimodal data analyses in preclinical models of neurological injury. Scientific Reports In Press 2024.

2023

Hubbard WB, Vekaria HJ, Kalimon OJ, Spry ML, Brown EP, Kilbaugh TJ, Sullivan PG.: Pioglitazone restores mitochondrial function but does not spare cortical tissue following mild brain contusion. Brain Commun 5: fcad032, Feb 2023. PMCID: PMC9985333

Slovis JC, Volk L, Mavroudis C, Hefti M, Landis WP, Roberts AL, Delso N, Hallowell T, Graham K, Starr J, Lin Y, Melchior R, Nadkarni V, Sutton RM, Berg RA, Piel S, Morgan RW, Kilbaugh TJ: Pediatric Extracorporeal Cardiopulmonary Resuscitation: Development of a Porcine Model and the Influence of Cardiopulmonary Resuscitation Duration on Brain Injury. J Am Heart Assoc 12(4): e026479, February 2023. PMCID: PMC10111482

O'Donnell JC, Browne KD, Kvint S, Makaron L, Grovola MR, Karandikar S, Kilbaugh TJ, Cullen DK, Petrov D.: Multimodal Neuromonitoring and Neurocritical Care in Swine to Enhance Translational Relevance in Brain Trauma Research. Biomedicines 11: 1336, Apr 2023. PMCID: PMC10216032

Forti RM, Hobson LJ, Benson EJ, Ko TS, Ranieri NR, Laurent G, Weeks MK, Widmann NJ, Morton S, Davis AM, Sueishi T, Lin Y, Wulwick KS, Fagan N, Shin SS, Kao SH, Licht DJ, White BR, Kilbaugh TJ, Yodh AG, Baker WB.: Non-invasive diffuse optical monitoring of cerebral physiology in an adult swine-model of impact traumatic brain injury. Biomed Opt Express 14: 2432-2448, May 2023. PMCID: PMC10278631

Shin SS, Chattaraj R, Viaene AN, Karmacharya MB, Haddad S, Degani R, Sridharan A, Sehgal C, Lee D, Kilbaugh TJ, Hwang M: Brain Targeted Xenon Protects Cerebral Vasculature after Traumatic Brain Injury. Journal of Neurotrauma Page: Online Ahead of Print, May 2023.

Shin SS, Mazandi VM, Schneider ALC, Morton S, Starr JP, Weeks MK, Widmann NJ, Jang DH, Kao SH, Ahlijanian MK, Kilbaugh TJ.: Exploring the Therapeutic Potential of Phosphorylated Cis-Tau Antibody in a Pig Model of Traumatic Brain Injury. Biomedicines 11: 1807, Jun 2023. PMCID: PMC10376756

Chilcote D, Sriram A, Slovis J, Morgan RW, Schaubel DE, Connelly J, Berg RA, Keim G, Yehya N, Kilbaugh T, Himebauch AS: Venovenous Extracorporeal Membrane Oxygenation Initiation for Pediatric Acute Respiratory Distress Syndrome With Cardiovascular Instability is Associated With an Immediate and Sustained Decrease in Vasoactive-Inotropic Scores. Pediatric Critical Care Medicine Epub ahead of print: e41-e46, July 2023. PMCID: PMC10768839

Kao SH, Shofer FS, Greenwood JC, Alomaja O, Ranganathan A, Piel S, Mesaros C, Shin SS, Ehinger JK, Kilbaugh TJ, Jang DH: Cell-Free DNA as a Biomarker in a Rodent Model of Chlorpyrifos Poisoning Causing Mitochondrial Dysfunction. J Med Toxicol July 2023. PMCID: PMC10522542

Silva LEV, Shi L, Gaudio H, Padmanabahn V, Morgan RW, Slovis JM, Forti RM, Morton S, Lin Y, Laurent GH, Breimann J, Yun B, Ranieri NR, Bowe M, Baker WB, Kilbaugh TJ, Ko TS, Tsui F: Prediction of Return of Spontaneous Circulation in a Pediatric Swine Model of Cardiac Arrest Using Low-Resolution Multimodal Physiological Waveforms. IEEE Journal of Biomedical and Health Informatics 27(10): 4719-4727, October 2023. PMCID: PMC10756325

Benson EJ, Aronowitz DI, Forti RM, Lafontant A, Ranieri NR, Starr JP, Melchior RW, Lewis A, Jahnavi J, Breimann J, Yun B, Laurent GH, Lynch JM, White BR, Gaynor JW, Licht DJ, Yodh AG, Kilbaugh TJ, Mavroudis CD, Baker WB, Ko TS.: Diffuse Optical Monitoring of Cerebral Hemodynamics and Oxygen Metabolism during and after Cardiopulmonary Bypass: Hematocrit Correction and Neurological Vulnerability. Metabolites 13: 1153, Nov 2023. PMCID: PMC10672802

Strong AE, Zee J, Fulchiero R, Kilbaugh TJ, Connelly J, Makeneni S, Campos D, Laskin BL, Denburg MR.: Intravascular Hemolysis and AKI in Children Undergoing Extracorporeal Membrane Oxygenation. Kidney360 4: 1536-1544, Nov 2023. PMCID: PMC10695640

Alomaja O, Shofer FS, Greenwood JC, Piel S, Clayman C, Mesaros C, Kao SH, Shin SS, Ehinger JK, Kilbaugh TJ, Jang DH.: Alteration in Cerebral Metabolism in a Rodent Model of Acute Sub-lethal Cyanide Poisoning. J Med Toxicol 2023. PMCID: PMC10050286

Greenwood JC, Talebi FM, Jang DH, Spelde AE, Gordon EK, Horak J, Acker MA, Kilbaugh TJ, Shofer FS, Augoustides JGT, Bakker J, Brenner JS, Muzykantov VR, Abella BS.: Low postoperative perfused vessel density is associated with increased soluble endothelial cell adhesion molecules during circulatory shock after cardiac surgery. Microvasc Res 2023. PMCID: PMC10530427

Lewis A, Forti RM, Alomaja O, Mesaros C, Piel S, Greenwood JC, Talebi FM, Mavroudis CD, Kelly M, Kao SH, Shofer FS, Ehinger JK, Kilbaugh TJ, Baker WB, Jang DH.: Correction to: Preliminary Research: Application of Non-Invasive Measure of Cytochrome c Oxidase Redox States and Mitochondrial Function in a Porcine Model of Carbon Monoxide Poisoning. J Med Toxicol 2023. PMCID: PMC9813311

Mazandi VM, Lang SS, Rahman RK, Nishisaki A, Beaulieu F, Zhang B, Griffis H, Tucker AM, Storm PB, Heuer GG, Gajjar AA, Ampah SB, Kirschen MP, Topjian AA, Yuan I, Francoeur C, Kilbaugh TJ, Huh JW.: Co-administration of Ketamine in Pediatric Patients with Neurologic Conditions at Risk for Intracranial Hypertension. Neurocrit Care 2023. PMCID: PMC10267668

Piel S, Janowska JI, Ward JL, McManus MJ, Aronowitz DI, Janowski PK, Starr J, Hook JN, Hefti MM, Clayman CL, Elmér E, Hansson MJ, Jang DH, Karlsson M, Ehinger JK, Kilbaugh TJ.: Succinate prodrugs as treatment for acute metabolic crisis during fluoroacetate intoxication in the rat. Mol Cell Biochem 2023. PMCID: PMC10540239

Shin SS, Chattaraj R, Viaene AN, Karmacharya MB, Haddad S, Degani R, Sridharan A, Sehgal C, Lee D, Kilbaugh TJ, Hwang M.: Brain Targeted Xenon Protects Cerebral Vasculature After Traumatic Brain Injury. J Neurotrauma 2023.

2022

Hwang M, Sridharan A, Freeman CW, Viaene AN, Kilbaugh TJ.: Contrast-Enhanced Ultrasound of Brain Perfusion in Cardiopulmonary Resuscitation. Ultrasound Q 38: 257-261, Feb 2022. PMCID: PMC9402813

Zhang Z, Hwang M, Kilbaugh TJ, Sridharan A, Katz J.: Cerebral microcirculation mapped by echo particle tracking velocimetry quantifies the intracranial pressure and detects ischemia. Nat Commun 13: 666, Feb 2022. PMCID: PMC8814032

Shin SS, Gottschalk AC, Mazandi VM, Kilbaugh TJ, Hefti MM.: Transcriptional Profiling in a Novel Swine Model of Traumatic Brain Injury. Neurotrauma Rep 3: 178-184, Apr 2022. PMCID: PMC9081013

Lang SS, Kumar NK, Zhao C, Zhang DY, Tucker AM, Storm PB, Heuer GG, Gajjar AA, Kim CT, Yuan I, Sotardi S, Kilbaugh TJ, Huh JW.: Invasive brain tissue oxygen and intracranial pressure (ICP) monitoring versus ICP-only monitoring in pediatric severe traumatic brain injury. J Neurosurg Pediatr 30: 239-249, May 2022.

Moon JK, Lawrence KM, Hunt ML, Davey MG, Flake AW, Licht DJ, Chen JM, Kilbaugh TJ, Gaynor JW, Beiting DP.: Chronic hypoxemia induces mitochondrial respiratory complex gene expression in the fetal sheep brain. JTCVS Open 10: 342-349, May 2022. PMCID: PMC9390414

Senthil K, Hefti MM, Singh LN, Morgan RW, Mavroudis CD, Ko T, Gaudio H, Nadkarni VM, Ehinger J, Berg RA, Sutton RM, McGowan FX, Kilbaugh TJ: Transcriptome and metabolome after porcine hemodynamic-directed CPR compared with standard CPR and sham controls. Resuscitation Plus 10(100243): 100243, June 2022. PMCID: PMC9111986

Bell MJ, Rosario BL, Kochanek PM, Adelson PD, Morris KP, Au AK, Schober M, Butt W, Edwards RJ, Zimmerman J, Pineda J, Le TM, Dean N, Whalen MJ, Figaji A, Luther J, Beers SR, Gupta DK, Carpenter J, Buttram S, Wisniewski SR; Approaches and Decisions for Acute Pediatric TBI (ADAPT) Investigators.: Comparative Effectiveness of Diversion of Cerebrospinal Fluid for Children With Severe Traumatic Brain Injury. JAMA Netw Open 5: e2220969, Jul 2022. PMCID: PMC9270700

Shin SS, Chawla S, Jang D, Mazandi VM, Weeks MK, Kilbaugh TJ.: Imaging of White Matter Injury Correlates with Plasma and Tissue Biomarkers in Pediatric Porcine Model of Traumatic Brain Injury. J Neurotrauma Jul 2022. PMCID: PMC9917326

White BR, Ko TS, Morgan RW, Baker WB, Benson EJ, Lafontant A, Starr JP, Landis WP, Andersen K, Jahnavi J, Breimann J, Delso N, Morton S, Roberts AL, Lin Y, Graham K, Berg RA, Yodh AG, Licht DJ, Kilbaugh TJ: Low Frequency Power in Cerebral Blood Flow is a Biomarker of Neurologic Injury in the Acute Period After Cardiac Arrest. Resuscitation 178: 12-18, July 2022.

White BR, Ko TS, Morgan RW, Baker WB, Benson EJ, Lafontant A, Starr JP, Landis WP, Andersen K, Jahnavi J, Breimann J, Delso N, Morton S, Roberts AL, Lin Y, Graham K, Berg RA, Yodh AG, Licht DJ, Kilbaugh TJ.: Low frequency power in cerebral blood flow is a biomarker of neurologic injury in the acute period after cardiac arrest. Resuscitation 178: 12-18, Jul 2022. PMCID: PMC9580006

Greenwood JC, Talebi FM, Jang DH, Spelde AE, Kilbaugh TJ, Shofer FS, Acker MA, Augoustides JGT, Bakker J, Meyer NJ, Brenner JS, Muzykantov VR, Abella BS.: Protocol for the MicroRESUS study: The impact of circulatory shock and resuscitation on microcirculatory function and mitochondrial respiration after cardiovascular surgery. PLoS One 17: e0273349, Aug 2022. PMCID: PMC9417024

Ko TS, Mavroudis CD, Benson EJ, Forti RM, Melchior RW, Boorady TW, Morano VC, Mensah-Brown K, Lin Y, Aronowitz D, Starr JP, Rosenthal TM, Shade BC, Schiavo KL, White BR, Lynch JM, Gaynor JW, Licht DJ, Yodh AG, Baker WB, Kilbaugh TJ.: Correlation of Cerebral Microdialysis with Non-Invasive Diffuse Optical Cerebral Hemodynamic Monitoring during Deep Hypothermic Cardiopulmonary Bypass. Metabolites 12: 737, Aug 2022. PMCID: PMC9416552

Greenwood JC, Talebi FM, Jang DH, Spelde AE, Tonna JE, Gutsche JT, Horak J, Acker MA, Kilbaugh TJ, Shofer FS, Augoustides JGT, Bakker J, Brenner JS, Muzykantov VR, Abella BS.: Topical nitroglycerin to detect reversible microcirculatory dysfunction in patients with circulatory shock after cardiovascular surgery: an observational study. Sci Rep 12: 15257, Sep 2022. PMCID: PMC9464203

Piel S, Janowska JI, Ward JL, McManus MJ, Jose JS, Starr J, Sheldon M, Clayman CL, Elmér E, Hansson MJ, Jang DH, Karlsson M, Ehinger JK, Kilbaugh TJ.: Succinate prodrugs in combination with atropine and pralidoxime protect cerebral mitochondrial function in a rodent model of acute organophosphate poisoning. Sci Rep 12: 20329, Nov 2022. PMCID: PMC9700731

Francoeur C, Landis WP, Winters M, Naim MY, Donoghue A, Dominick CL, Huh JW, MacDonald JM, Lang SS, Yuan I, Berg RA, Nadkarni VM, Kilbaugh TJ, Sutton RM, Kirschen MP, Morgan RW, Topjian AA.: Near-infrared spectroscopy during cardiopulmonary resuscitation for pediatric cardiac arrest: A prospective, observational study. Resuscitation 2022. PMCID: PMC9724995

Hwang M, Tierradentro-García LO, Haddad S, Poznick L, Kilbaugh T, Chiotos K.: Feasibility of Contrast-Enhanced Ultrasound for Assessing Cardiac and Renal Microvascular Flow in Patients With Multisystem Inflammatory Syndrome in Children. Clin Pediatr (Phila) 2022.

Lang SS, Gajjar AA, Tucker AM, Storm PB, Rahman RK, Madsen PJ, O'Brien A, Chiotos K, Kilbaugh TJ, Huh JW.: Urgent Neurosurgical Interventions in the COVID-19-Positive Pediatric Population. World Neurosurg 2022. PMCID: PMC8550883

Lewis AT, Forti RM, Alomaja O, Mesaros C, Piel S, Greenwood JC, Talebi FM, Mavroudis CD, Kelly M, Kao SH, Shofer FS, Ehinger JK, Kilbaugh TJ, Baker WB, Jang DH.: Preliminary Research: Application of Non-Invasive Measure of Cytochrome c Oxidase Redox States and Mitochondrial Function in a Porcine Model of Carbon

Rosner EA, L Parker J, Vandenberg C, Bridges BC, Kilbaugh TJ, Bembea MM, Chima RS, Potera RM, Sandhu HS, Barbaro RP, Tarquinio KM, Cheifetz IM, Friedman ML.: Flexible Bronchoscopy in Pediatric Venovenous Extracorporeal Membrane Oxygenation. Respir Care 2022.

Shin SS, Hefti MM, Mazandi VM, Issadore DA, Meaney DF, Schneider ALC, Diaz-Arrastia R, Kilbaugh TJ.: Plasma Neurofilament Light and Glial Fibrillary Acidic Protein Levels over Thirty Days in a Porcine Model of Traumatic Brain Injury. J Neurotrauma 2022. PMCID: PMC9836679

Shin SS, Sridharan A, Khaw K, Hallowell T, Morgan RW, Kilbaugh TJ, Hwang M.: Intracranial Pressure and Cerebral Hemodynamic Monitoring After Cardiac Arrest in Pediatric Pigs Using Contrast Ultrasound-Derived Parameters. J Ultrasound Med 2022. PMCID: PMC8920953

2021

Bender D, Morgan RW, Nadkarni VM, Berg RA, Zhang B, Kilbaugh TJ, Sutton RM, Nataraj C: : MILWAVE: A novel algorithm to classify primary versus secondary asphyxia-associated ventricular fibrillation. Resuscitation Plus 5: 10052, March 2021.

Himebauch AS, Wong W, Wang Y, McGowan FX, Berg RA, Mascio CE, Kilbaugh TJ, Lin KY, Goldfarb SB, Kawut SM, Mercer-Rosa L, Yehya N: Preoperative echocardiographic parameters predict primary graft dysfunction following pediatric lung transplantation. Pediatric Transplant 25(2): e13858, March 2021.

Morgan RW, Sutton RM, Himebauch AS, Roberts AL, Landis WP, Lin Y, Starr J, Ranganathan A, Delso N, Mavroudis CD, Volk L, Slovis J, Marquez AM, Nadkarni VM, Hefti M, Berg RA, Kilbaugh TJ: A randomized and blinded trial of inhaled nitric oxide in a piglet model of pediatric cardiopulmonary resuscitation. Resuscitation 162: 274-283, May 2021. PMCID: PMC8096708

Padawer-Curry JA, Volk LE, Mavroudis CD, Ko TS, Morano VC, Busch DR, Rosenthal TM, Melchior RW, Shade BC, Schiavo KL, Schmidt AL, Andersen KN, Breimann JS, Jahnavi J, Mensah-Brown KG, Yodh AG, Mascio CE, Kilbaugh TJ, Licht DJ, White BR, Baker WB: Effects of circulatory arrest and cardiopulmonary bypass on cerebral autoregulation in neonatal swine. Pediatric Research May 2021 Notes: Epub ahead of print. PMCID: PMC8566324

Karlsson M, Yang Z, Chawla S, Delso N, Pukenas B, Elmér E, Hugerth M, Margulies SS, Ehinger J, Hansson MJ, Wang KKW, Kilbaugh TJ.: Evaluation of Diffusion Tensor Imaging and Fluid Based Biomarkers in a Large Animal Trial of Cyclosporine in Focal Traumatic Brain Injury. J Neurotrauma 38: 1870-1878, Jun 2021.

Senthil K, Morgan RW, Hefti MM, Karlsson M, Lautz AJ, Mavroudis CD, Ko T, Nadkarni VM, Ehinger J, Berg RA, Sutton RM, McGowan FX, Kilbaugh TJ: Haemodynamic-directed cardiopulmonary resuscitation promotes mitochondrial fusion and preservation of mitochondrial mass after successful resuscitation in a pediatric porcine model. Resuscitation Plus 6: 100124, June 2021. PMCID: PMC8244484

Volk L, Mavroudis CD, Ko T, Hallowell T, Delso N, Roberts AL, Starr J, Landis W, Lin Y, Hefti M, Morgan RW, Melchior RW, Rosenthal TM, Chappell A, Fisher D, Dreher M, Licht DJ, Chen J, Gaynor JW, Mascio CE, Kilbaugh TJ: Increased cerebral mitochondrial dysfunction and reactive oxygen species with cardiopulmonary bypass. European Journal of Cardio-Thoracic Surgery 59(6): 1256-1264, June 2021. PMCID: PMC8203249

Lang SS, Valeri A, Storm PB, Heuer GG, Tucker AM, Kennedy BC, Kozyak BW, Sinha A, Kilbaugh TJ, Huh JW.: Acute neurological injury in pediatric patients with single-ventricle congenital heart disease. J Neurosurg Pediatr Jul 2021.

Troy L, Su F, Kilbaugh T, Rasmussen L, Kuo T, Jett E, Cornell T, Berg M, Haileselassie B.: Characteristics of Pediatric Extracorporeal Membrane Oxygenation Programs in the United States and Canada. ASAIO J 67: 792-797, Jul 2021.

Bridges BC, Kilbaugh TJ, Barbaro RP, Bembea MM, Chima RS, Potera RM, Rosner EA, Sandhu HS, Slaven JE, Tarquinio KM, Cheifetz IM, Rowan CM, Friedman ML; Pediatric ECMO (Pediecmo) Subgroup of the Pediatric Acute Lung Injury and Sepsis Investigators (PALISI) Network and the Extracorporeal Life Support Organization (ELSO).: Veno-Venous Extracorporeal Membrane Oxygenation for Children With Cancer or Hematopoietic Cell Transplant: A Ten Center Cohort. ASAIO J 67: 923-929, Aug 2021. PMCID: PMC8328899

Greenwood JC, Jang DH, Spelde AE, Gutsche JT, Horak J, Acker MA, Kilbaugh TJ, Shofer FS, Augoustides JGT, Bakker J, Abella BS.: Low Microcirculatory Perfused Vessel Density and High Heterogeneity are Associated With Increased Intensity and Duration of Lactic Acidosis After Cardiac Surgery with Cardiopulmonary Bypass. Shock 56: 245-254, Aug 2021.

Lang SS, Kilbaugh T, Friess S, Sotardi S, Kim CT, Mazandi V, Zhang B, Storm PB, Heuer GG, Tucker A, Ampah SB, Griffis H, Raghupathi R, Huh JW.: Trajectory of Long-Term Outcome in Severe Pediatric Diffuse Axonal Injury: An Exploratory Study. Front Neurol 12: 704576, Sep 2021. PMCID: PMC8477000

Lang SS, Kilbaugh T, Friess S, Sotardi ST, Kim CT, Mazandi V, Zhang B, Storm P, Heuer GG, Tucker A, Ampah SB, Griffis H, Raghupathi R, Huh JW: Trajectory of long-term outcome in severe pediatric diffuse axonal injury: An exploratory study. Frontiers in Neurology- Neurotrauma 12: 704576, September 2021 Notes: Published on Line.

Kienzle MF, Morgan RW, Faeber JA, Graham K, Katcoff H, Landis WP, Topjian AA, Kilbaugh TJ, Nadkarni VM, Berg RA, Sutton RM: The effect of epinephrine dosing intervals on outcomes from pediatric in-hospital cardiac arrest. American Journal of Respiratory and Critical Care Medicine 204(8): 977-985, October 2021.

Kienzle MF, Morgan RW, Faerber JA, Graham K, Katcoff H, Landis WP, Topjian AA, Kilbaugh TJ, Nadkarni VM, Berg RA, Sutton RM.: The Effect of Epinephrine Dosing Intervals on Outcomes from Pediatric In-Hospital Cardiac Arrest. Am J Respir Crit Care Med 204: 977-985, Oct 2021. PMCID: PMC8534618

Lang SS, Tucker AM, Schreiber C, Storm PB, Liu H, Li Y, Ichord R, Beslow LA, Sedora-Roman NI, Cox M, Nasser H, Vossough A, Fisher MJ, Kilbaugh TJ, Huh JW.: Arterial spin labeling as an ancillary assessment to postoperative conventional angiogram in pediatric moyamoya disease. J Neurosurg Pediatr 29: 40-47, Oct 2021.

Lang SS, Valeri A, Storm PB, Heuer GG, Tucker AM, Kennedy BC, Kozyak BW, Sinha A, Kilbaugh TJ, Huh JW: Arterial spin labeling as an ancillary assessment to postoperative conventional angiogram in pediatric moyamoya disease Journal of Neurosurgery Pediatrics 1: 1-8, October 2021.

Kirschen MP, Majmudar T, Beaulieu F, Burnett R, Shaik M, Morgan RW, Baker W, Ko T, Balu R, Agarwal K, Lourie K, Sutton RM, Kilbaugh TJ, Diaz-Arrastia, R, Berg RA, Topjian AA: Deviations from NIRS-derived optimal blood pressure are associated with worse outcomes after pediatric cardiac arrest. Resuscitation 168: 110-118, November 2021. PMCID: PMC9150719

Morgan RW, Himebauch AS, Griffs H, Quarshie WO, Yeung T, Kilbaugh TJ, Topjian AA, Traynor D, Nadkarni VM, Berg RA, Nishisaki A, Sutton RM: Pulmonary hypertension among children with in-hospital cardiac arrest: a multicenter study. Resuscitation a168: 52-57, November 2021.

Bender D, Morgan RW, Nadkarni VM, Berg RA, Zhang B, Kilbaugh TJ, Sutton RM, Nataraj C.: MLWAVE: A novel algorithm to classify primary versus secondary asphyxia-associated ventricular fibrillation. Resusc Plus 2021. PMCID: PMC7869586

Ehinger JK, Karlsson M, Sjövall F, Leffler M, McCormack SE, Kubis SE, Åkesson A, Falk MJ, Kilbaugh TJ.: Predictors of outcome in children with disorders of mitochondrial metabolism in the pediatric intensive care unit. Pediatr Res 2021. PMCID: PMC7903037

Greenwood JC, Jang DH, Hallisey SD, Gutsche JT, Horak J, Acker MA, Bermudez CA, Zhou VL, Chatterjee S, Shofer FS, Kilbaugh TJ, Augoustides JGT, Meyer NJ, Bakker J, Abella BS.: Severe Impairment of Microcirculatory Perfused Vessel Density Is Associated With Postoperative Lactate and Acute Organ Injury After Cardiac Surgery. J Cardiothorac Vasc Anesth 2021. PMCID: PMC7666105

Jang DH, Piel S, Greenwood JC, Kelly M, Mazandi VM, Ranganathan A, Lin Y, Starr J, Hallowell T, Shofer FS, Baker WB, Lafontant A, Andersen K, Ehinger JK, Kilbaugh TJ.: Alterations in cerebral and cardiac mitochondrial function in a porcine model of acute carbon monoxide poisoning. Clin Toxicol (Phila) 2021. PMCID: PMC8326298

Mallory PP, Barbaro RP, Bembea MM, Bridges BC, Chima RS, Kilbaugh TJ, Potera RM, Rosner EA, Sandhu HS, Slaven JE, Tarquinio KM, Cheifetz IM, Friedman ML.: Tracheostomy and long-term mechanical ventilation in children after veno-venous extracorporeal membrane oxygenation. Pediatr Pulmonol 2021.

Morgan RW, Himebauch AS, Griffis H, Quarshie WO, Yeung T, Kilbaugh TJ, Topjian AA, Traynor D, Nadkarni VM, Berg RA, Nishisaki A, Sutton RM.: Pulmonary hypertension among children with in-hospital cardiac arrest: A multicenter study. Resuscitation 2021. PMCID: PMC8551027

Shin S, Sridharan A, Khaw K, Hallowell T, Morgan RW, Kilbaugh TJ, Hwang M: Intracranial pressure and cerebral hemodynamic monitoring after cardiac arrest in pediatric pigs using contrast ultrasound derived parameters. Journal of Ultrasound in Medicine In Press 2021.

2020

Ko TS, Mavroudis CD, Baker WB, Morano VC, Menash-Brown K, Boorady TW, Schmidt AL, Lynch JM, Busch DR, Gentile J, Bratinov G, Lin Y, Jeong S, Melchior RW, Rosenthal TM, Shade BC, Schiavo KL, Xiao R, Gaynor JW, Yodh AG, Kilbaugh TJ, Licht DJ: Non-invasive optical neuromonitoring of the temperature-dependence of cerebral oxygen metabolism during deep hypothermic cardiopulmonary bypass in neonatal swine. Journal of Cerebral Blood Flow and Metabolism 40(1): 1187-1203, January 2020.

Janowska JI, Piel S, Saliba N, Kim CD, Jang DH, Karlsson M, Kilbaugh TJ, Ehinger JK: Mitochondrial respiratory chain complex I dysfunction induced by N-methyl carbamate ex vivo can be alleviated with a cell-permeable succinate prodrug. Toxicology In Vitro 65: 104794, February 2020.

Friedman ML, Barbaro RP, Bembea MM, Bridges BC, Chima RS, Kilbaugh TJ, Pandiyan P, Potera RM, Rosner EA, Sandhu HS, Slaven JE, Tarquinio KM, Cheifetz IM: Mechanical ventilation in children on venovenous ECMO. Respiratory Care 65(3): 271-280, March 2020.

Hajiaghamemar M, Kilbaugh TJ, Arbogast KB, Master CL, Margulies SS: Using serum amino acids to predict traumatic brain injury: A systematic approach to utilize multiple biomarkers. International Journal of Molecular Sciences 21(5): 1-27, March 2020.

Morgan RW, Topjian AA, Wang Y, Atkin NJ, Kilbaugh TJ, McGowan FX, Berg RA, Mercer-Rosa L, Sutton RM, Himebauch AS: Prevalence and outcomes of pediatric in-hospital cardiac arrest associated with pulmonary hypertension. Pediatric Critical Care Medicine 21(4): 305-313, April 2020.

Greenwood JC, Jang DH, Hallisey SD, Gutsche JT, Horak J, Acker MA, Bermudez CA, Zhou VL, Chatterjee S, Shofer FS, Kilbaugh TJ, Augoustides JGT, Meyer NJ, Bakker J, Abella BS: Severe impairment of microcirculatory perfused vessel density is associated with postoperative lactate and acute organ injury after cardiac surgery. J Cardiothorac Vasc Anesth 35(1): 106-115, June 2020.

Morgan RW, Reeder RW, Meert KL, Telford R, Yates AR, Berger JT, Graham K, Landis WP, Kilbaugh TJ, Newth CJ, Carcillo JA, McQuillen PS, Harrison RE, Moler FW, Pollack MM, Carpenter TC, Notterman D, Holubkov R, Dean M, Nadkarni VM, Berg RA, Sutton RM: Survival and hemodynamics during pediatric cardiopulmonary resuscitation for bradycardia and poor perfusion versus pulseless cardiac arrest. Critical Care Medicine 48(6): 881-889, June 2020.

Kirschen MP, Yehya N, Graham K, Kilbaugh TJ, Berg RA, Topjian A, Diaz-Arrastia R: Circulating neurofilament light chain is associated with survival after pediatric cardiac arrest. Pediatric Critical Care Medicine 21(7): 656-661, July 2020.

Lang SS, Valeri A, Zhang B, Storm PB, Heuer GG, Leavesley L, Bellah R, Kim CT, Griffis H, Kilbaugh TJ, Huh JW: Head of bed elevation in pediatric patients with severe traumatic brain injury. Journal of Neurosurgery - Pediatrics 26(5): 1-11, July 2020.

Loaec M, Himebauch AS, Kilbaugh TJ, Berg RA, Graham K, Hanna R, Wolfe HA, Sutton RM, Morgan RW: Pediatric cardiopulmonary resuscitation quality during intra-hospital transport. Resuscitation 152: 123-130, July 2020.

Welch TP, Kilbaugh TJ, McCloskey JJ, Juriga LL, Abdallah AB, Fehr JJ: The Current State of Combined Pediatric Anesthesiology-Critical Care Practice: A Survey of Dual-Trained Practitioners in the United States. Anesthesia and Analgesia 132(1): 194-201, July 2020.

Morgan RW, Kienzle M, Sen AI, Kilbaugh TJ, Dewan M, Raymond TT, Himebauch AS, Berg RA, Tegtmeyer K, Nadkarni VM, Topjian AA, Sutton RM, Wolfe HA: Pediatric resuscitation practices during the COVID-19 pandemic. Pediatric Critical Care Medicine 21(9): e651-e660, September 2020.

Diorio C, Anderson E, McNerney K, Goodwin E, Chase J, Bolton M, Arevalo C, Weirick M, Gouma S, Vella L, Henrickson S, Chiotos K, Fitzgerald JC, Kilbaugh TJ, John A, Blatz A, Lambert M, Sullivan K, Tartaglione M, Zambrano D, Martin M, Lee J, Young P, Friedman D, Sesok-Pizzini D, Hensley S, Behrens E, Bassiri H, Teachey D: Convalescent plasma for pediatric patients with COVID-19 associated acute respiratory distress syndrome. Pediatric Blood & Cancer 67(11): e28693, November 2020.

Diorio C, Henrickson SE, Vella LA, McNerney KO, Chase JM, Burudpakdee C, Lee JH. Jasen C, Balamuth F, Barrett DM, Banwell B, Bernt KM, Blatz AM, Chiotos K, Fisher BT, Fitzgerald JC, Gerber JS, Gollomp K, Gray C, Grupp SA, Harris RM, Kilbaugh TJ, Odom John AR, Lambert MP, Liebling EJ, Paessler M, Petrosa W, Phillips CA, Reilly AF, Romberg N, Seif AE, Sesok-Pizzini D, Sullivan K, Vardaro J, Behrens EM, Teachey DT, Bassiri H: Multisystem inflammatory syndrome in children and COVID-19 are distinct presentations of SARS-CoV-2. Journal of Clinical Investigation 130(11): 5967-5975, November 2020.

Busch DR, Baker WB, Mavroudis CD, Ko TS, Lynch JM, McCarthy AL, DuPont-Thibodeau G, Buckley EM, Jacobwitz M, Boorady TW, Mensah-Brown K, Connelly JT, Yodh AG, Kilbaugh TJ, Licht DJ: Noninvasive optical measurement of microvascular cerebral hemodynamics and autoregulation in the neonatal ECMO patient. Pediatr Res 88(6): 925-933, Decembr 2020. PMCID: PMC7492409

Kirschen MP, Morgan RW, Majmudar T, Landis WP, Ko T, Balu R, Balasubramanian S, Topjian A, Sutton RM, Berg RA, Kilbaugh TJ: The association between early impairment in cerebral autoregulation and outcome in a pediatric swine model of cardiac arrest. Resuscitation Plus 4: 100051, December 2020.

Mavroudis CD, Ko T, Volk LE, Smood B, Morgan RW, Lynch JM, Davarajan M, Boorady TW, Licht DJ, Gaynor JW, Mascio CE, Kilbaugh TJ: Does supply meet demand? A comparison of perfusion strategies on cerebral metabolism in a neonatal swine model. J Thorac Cardiovasc Surg S0022-5223(20): 33317, December 2020. PMCID: PMC8862716

Owiredu S, Ranganathan A, Greenwood JC, Piel S, Janowska JI, Eckmann DM, Kelly M, Ehinger JK, Kilbaugh TJ, Jang DH: In vitro comparison of hydroxocobalamin (B12a) and the mitochondrial directed therapy by a succinate prodrug in a cellular model of cyanide poisoning. Toxicology Reports 7: 1263-1271, 2020.

Slovis JC, Morgan RW, Landis WP, Roberts AL, Marquez AM, Mavroudis CD, Lin Y, Ko T, Nadkarni VM, Berg RA, Sutton RM, Kilbaugh TJ: The physiologic response to rescue Therapy with vasopressin versus epinephrine during experimental pediatric cardiac arrest. Resuscitation Plus 4: 100050, December 2020.

2019

Lautz AJ, Morgan RW, Karlsson M, Mavroudis CD, Ko TS, Licht DJ, Nadkarni VM, Berg RA, Sutton RM, Kilbaugh TJ: Hemodynamic-directed CPR improves neurologic outcomes and mitochondrial function in heart and brain. Critical Care Medicine 47(3): e241-e249, March 2019 Notes: *Lautz and Morgan - co-first authors; +Kilbaugh and Sutton - co-senior authors.

Morgan RW, Landis WP, Marquez A, Graham K, Roberts AL, Lauridsen KG, Wolfe HA, Nadkarni VM, Topjian AA, Berg RA, Kilbaugh TJ, Sutton RM: Hemodynamic effects of chest compression interruptions during pediatric in-hospital cardiopulmonary resuscitation. Resuscitation 139: 1-8, June 2019.

Weiss SL, Zhang D, Bush J, Graham K, Starr J, Tuluc F, Henrickson S, Kilbaugh TJ, Deutschman CS, Murdock D, McGowan FX, Becker L, Wallace DC : Persistent mitochondrial dysfunction linked to prolonged organ dysfunction in pediatric sepsis. Critical Care Medicine 47(10): 1433-1441, October 2019.

Kelsen J, Karlsson M, Hansson MJ, Yang Z, Fischer W, Hugerth M, Nordström CH, Åstrand R, Keep MF, Kilbaugh TJ, Wang KKW, Moeller K, Juhler M, Elmér E: Copenhagen Head Injury Ciclosporin (CHIC) study: A phase IIa safety, pharmacokinetics and biomarker study of ciclosporin in severe head injury patients. Journal of Neurotrauma 36(23): 3253-3263, December 2019.

2018

Morgan RW, Stinson HR, Wolfe HA, Lindell RB, Topjian AA, Nadkarni VM, Sutton RM, Berg RA, Kilbaugh TJ: Pediatric in-hospital cardiac arrest secondary to acute pulmonary embolism. Critical Care Medicine 46(3): e229-e234, March 2018.

Morgan RW, Sutton RM, Karlsson M, Lautz AJ, Mavroudis CD, Landis WP, Jeong S, Craig N, Nadkarni VM, Kilbaugh TJ, Berg RA: Pulmonary vasodilator therapy in shock-associated cardiac arrest. American Journal of Respiratory and Critical Care Medicine 197(7): 905-912, April 2018.

Karlsson M, Pukenas B, Chawla S, Ehinger JK, Plyler R, Stolow M, Gabello M, Hugerth M, Elmér E, Hansson MJ, Margulies S, Kilbaugh TJ: Neuroprotective effects of cyclosporine in a porcine pre-clinical trial of focal traumatic brain injury. Journal of Neurotrauma 36(1): 14-24, July 2018.

Mavroudis CD, Karlsson M, Ko T, Hefti M, Gentile JI, Morgan RW, Plyler R, Mensah-Brown KG, Boorady TW, Melchior RW, Rosenthal TM, Shade BC, Schiavo KL, Nicolson SC, Spray TL, Sutton RM, Berg RA, Licht DJ, Gaynor JW, Kilbaugh TJ: Cerebral mitochondrial dysfunction associated with deep hypothermic circulatory arrest in neonatal swine. European Journal of Cardio-Thorac Surgery 54(1): 162-168, July 2018.

Himebauch AS, Yehya N, Yan W, Conlon TW, Kilbaugh TJ, McGowan FX, Mercer-Rosa L: Early right ventricular systolic dysfunction and pulmonary hypertension are associated with worse outcomes in pediatric acute respiratory distress syndrome. Critical Care Medicine 46(11): e1029-e1039, November 2018.

Mavroudis CD, Mensah-Brown KG, Ko TS, Boorady TW, Massey SL, Abend NS, Nicolson SC, Morgan RW, Mascio CE, Gaynor JW, Kilbaugh TJ, Licht DL: Electroencephalographic response to deep hypothermic circulatory arrest in neonatal swine and humans. Annals of Thoracic Surgery 106(6): 1841-1846, December 2018.

2017

Simpao AF, Ahumada LM, Gálvez JA, Bonafide CP, Wartman EC, Randall England W, Lingappan AM, Kilbaugh TJ, Jawad AF, Rehman MA: The timing and prevalence of intraoperative hypotension in infants undergoing laparoscopic pyloromyotomy at a tertiary pediatric hospital. Paediatric Anaesthesia 27(1): 66-76, January 2017.

Morgan RW, Kilbaugh TJ, Shoap W, Bratinov G, Lin Y, Hsieh TC, Nadkarni VM, Berg RA, Sutton RM: A hemodynamic-directed approach to pediatric cardiopulmonary resuscitation (HD-CPR) improves survival. Resuscitation 111: 41-47, February 2017.

Lin J, Banwell BL, Berg RA, Dlugos DJ, Ichord RN, Kilbaugh TJ, Kirsch RE, Kirschen MP, Licht DJ, Massey SL, Naim MY, Rintoul NE, Topjian AA, Abend NS: Electrographic seizures in children and neonates undergoing extracorporeal membrane oxygenation. Pediatric Critical Care Medicine 18(3): 249-257, March 2017.

McCormack SE, Xiao R, Kilbaugh TJ, Karlsson M, Ganetzky RD, Cunningham ZZ, Goldstein A, Falk MJ, Damrauer SM: Hospitalizations for mitochondrial disease across the lifespan in the US. Molecular Genetics and Metabolism 121(2): 119-126, June 2017.

Miller NF, Sarnaik A, Miles D, Shafi N, Peters MJ, Truemper E, Vavilala MS, Bell MJ, Wisniewski SR, Luther JF, Hartman AL, Kochanek PM, Investigators of the Approaches and Decisions in Acute Pediatric Traumatic Brain Injury (ADAPT) Trial: Abusive Head Trauma and Mortality-An Analysis From an International Comparative Effectiveness Study of Children With Severe Traumatic Brain Injury. Critical Care Medicine 45(8): 1398-1407, Aug 2017 Notes: Kilbaugh TJ member of Investigators of the Approaches and Decisions in Acute Pediatric Traumatic Brain Injury (ADAPT) Trial. PMCID: PMC5511066

2016

Kilbaugh TJ, Karlsson M, Duhaime AC, Hansson MJ, Elmer E, Margulies SS: Mitochondrial response in a toddler-aged swine model following diffuse non-impact traumatic brain injury. Mitochondrion 26: 19-25, January 2016. PMCID: PMC4752861

Lasa JJ, Rogers RS, Localio R, Shults J, Raymond T, Gaies M, Thiagarajan R, Laussen PC, Kilbaugh TJ, Berg RA, Nadkarni VM: Extracorporeal-cardiopulmonary resuscitation (E-CPR) during pediatric in-hospital cardiopulmonary arrest is associated with improved survival to discharge: A Report from the American Heart Association's Get With the Guidelines - Resuscitation Registry (GWTG-R). Circulation 133(2): 165-76, January 2016. PMCID: PMC4814337

Karlsson M, Hara N, Morata S, Sjovall F, Kilbaugh TJ, Hansson MJ, Uchino H, Elmer E: Diverse and tissue specific mitochondrial respiratory response in a mouse model of sepsis-induced multiple organ failure. Shock 45(4): 404-410, April 2016.

Ferguson MA, Sutton RM, Karlsson M, Sjovall F, Becker LB, Berg RA, Margulies SS, Kilbaugh TJ: Increased platelet mitochondrial respiration after cardiac arrest and resuscitation as a potential peripheral biosignature of cerebral bioenergetics dysfunction. Journal of Bioenergetics and Biomembranes 48(3): 269-279, June 2016.

Himebauch AS, Sankar WW, Flynn JM, Sisko M, Moorthy G, Gerber JS, Zuppa AF, Fox E, Dormans JP, Kilbaugh TJ: Skeletal muscle and plasma concentrations of cefazolin during complex pediatric spinal surgery. British Journal of Anesthesia 117(1): 87-94, July 2016.

Morgan RW, French B, Kilbaugh TJ, Naim MY, Wolfe HA, Bratinov G, Shoap W, Hsieh TC, Nadkarni VM, Berg RA, Sutton RM: A quantitative comparison of physiologic indicators of cardiopulmonary resuscitation quality: Diastolic blood pressure versus end-tidal carbon dioxide. Resuscitation 104: 6-11, July 2016.

Naim Maryam Y, Sutton Robert M, Friess Stuart H, Bratinov George, Bhalala Utpal, Kilbaugh Todd J, Lampe Joshua W, Nadkarni Vinay M, Becker Lance B, Berg Robert A: Blood Pressure- and Coronary Perfusion Pressure-Targeted Cardiopulmonary Resuscitation Improves 24-Hour Survival From Ventricular Fibrillation Cardiac Arrest. Critical Care Medicine 44(11): e1111-e1117, Nov 2016. PMCID: PMC5069077

2015

Clevenger AC, *Kilbaugh TJ, *Margulies SS: Carotid artery blood flow decreases after rapid head rotation in piglets. Journal of Neurotrauma 32(2): 120-126, January 2015 Notes: *These two authors contributed equally to the manuscript.

Friess SH, Bruins B, Kilbaugh TJ, Smith C, Margulies SS: Differing effects when using phenylephrine and norephinephrine to augment cerebral blood flow after traumatic brain injury in the immature brain. Journal of Neurotrauma 32(4): 237-243, February 2015.

*Margulies SS, *Kilbaugh TJ, Sullivan S, Smith C, Propert K, Byro M, Saliga K, Costine BA, Duhaime AC: Establishing a clinically relevant large animal model platform for TB therapy development: Using cyclosporine A as a case study. Brain Pathology 25(3): 289-303, May 2015 Notes: These two authors contributed equally to the manuscript.

Faro A, Wood RE, Schechter MS, Leong AB, Wittkugel E, Abode K, Chmiel JF, Daines C, Davis S, Eber E, Huddleston C, Kilbaugh TJ, Kurland G, Midulla F, Molter D, Montgomery GS, Retsch-Bogart G, Rutter MJ, Visner G, Walczak SA, Ferkol TW, Michelson PH; American Thoracic Society Ad Hoc Committee on Flexible Airway Endoscopy in Children: Official American Thoracic Society Technical Standards: Flexible airway endoscopy in children. American Journal of Respiratory Critical Care Medicine 191(9): 1066-1080, May 2015.

Kilbaugh TJ, Lvova M, Karlsson M, Zhang Z, Leopzig J, Wallace DC, Margulies SS: Peripheral blood mitochondrial DNA as a biomarker of cerebral mitochondrial dysfunction following traumatic brain injury in a porcine model. PLoS 10(6): e0130927, June 2015.

Fiadjoe JE, Hirschfeld M, Wu S, Markley J, Gurnaney H, Jawad AF, Stricker P, Kilbaugh TJ, Ross P, Kovatisis P: A randomized multi-institutional crossover comparison of the GlideScope Cobalt Video laryngoscopy to the flexible fiberoptic bronchoscope in a Pierre Robin manikin. Paediatric Anaesthesia 25(8): 801-806, August 2015.

Jaber SM, Sullivan S, Hanekenson FC, *Kilbaugh TJ, *Margulies SS: Comparison of heart rate and blood pressure with toe pinch and bispectral index for monitoring the depth of anesthesia in piglets. Journal of the American Association for Laboratory Animal Science 54(5): 1-9, September 2015 Notes: *These two authors contributed equally to the manuscript.

Kilbaugh TJ, Karlsson M, Byro M, Bebee A, Ralston J, Sullivan S, Duhaime AC, Hansson MJ, Elmer E, Margulies SS: Mitochondrial bioenergetic alterations after focal traumatic brain injury in the immature brain. Experimental Neurology 271: 136-144, September 2015. PMCID: PMC4586357

Kilbaugh TJ, Himebauch AS, Zaoutis T, Jobes D, Greeley WJ, Nicholson SC, Zuppa AF: A pilot and feasibility study of the plasma and tissue pharmacokinetics of cefazolin in an immature porcine model of pediatric cardiac surgery. Pediatric Anesthesia 25(11): 1111-1119, November 2015.

2014

*Maude SL, *Fitzgerald JC, Fisher BT, Li Y, Huang Y, Torp K, Seif AE, Kavcic M, Walker DM, Leckerman KH, Kilbaugh TJ, Rheingold SR, Sung L, Zaoutis TE, Berg RA, Nadkarni VM, Thomas NJ, Aplenc R: Outcome of pediatric acute myeloid leukemia patients receiving intensive care in the United States. Pediatric Critical Care Medicine 15(2): 112-120, February 2014 Notes: *These two authors contributed equally to the manuscript

Yehya N, Dominick CL, Connelly JT, Davis DH, Minneci PC, Deans KJ, McCloskey JJ, Kilbaugh TJ: High frequency percussive ventilation and bronchoscopy during extracorporeal life support in children. ASAIO Journal 60(4): 424-428, July-August 2014.

Sulkowski JP, Cooper JN, Pearson EG, Connelly JT, Rintoul N, Kilbaugh TJ, Deans KJ, Minneci PC: Hemolysis-associated nitric oxide dysregulation during extracorporeal membrane oxygenation. The Journal of ExtraCorporeal Technology 46(3): 217-223, September 2014.

Topjian AA, Stuart A, Pabalan AA, Clair A, Kilbaugh TJ, Abend NS, Berg RA, Heuer GG, Storm PB, Huh JW, Friess SH: Risk factors associated with infections and need for permanent cerebrospinal fluid diversion in pediatric intensive care patients with externalized ventricular drains. Neurocritical Care 21(2): 294-299, October 2014.

Topjian AA, Stuart A, Pabalan AA, Clair A, Kilbaugh TJ, Abend NS, Storm PB, Berg RA, Huh JW, Friess SH: Greater fluctuations in serum sodium levels are associated with increased mortality I children with externalized ventriculostomy drains in a pediatric intensive

Himebauch AS, Nicolson SC, Sisko M, Moorthy G, Fuller S, Gaynor JW, Zuppa AF, Fox E, Kilbaugh TJ: Skeletal muscle and plasma concentrations of cefazolin during cardiac surgery in infants. Journal of Thoracic Cardiovascular Surgery 148(6): 2634-2641, December 2014.

Weeks D, Sullivan S, Kilbaugh TJ, Smith C, Margulies SS: Influences of developmental age on the resolution of diffuse traumatic intracranial hemorrhage and axonal injury. Journal of Neurotrauma 31(2): 206-214, 2014.

2013

Minneci PC, Kilbaugh TJ, Chandler HK, Behar BJ, Localio AR, Deans KJ: Factors associated with mortality in pediatric patients requiring extracorporeal life support for severe pneumonia. Pediatric Critical Care Medicine 14(1): e26-e33, January 2013.

Bruins B, Kilbaugh TJ, Margulies SS, Friess SH: The anesthetic effect on vasopressor modulation of cerebral blood flow in an immature swine model. Anesthesia and Analgesia 116(4): 838-844, April 2013.

Hasbani DM, Topjian AA, Friess SH, Kilbaugh TJ, Berg RA, Christian CW, Dlugos DJ, Huh JW, Abend NS: Non-convulsive electrographic seizures are common in children with abusive head trauma. Pediatric Critical Care Medicine 14(7): 709-715, September 2013.

2012

Friess SH, Naim, MY, Kilbaugh TJ, Ralston J, Margulies SS: Premedication with meloxicam exacerbates intracranial hemorrhage in an immature swine model of non-impact head injury. Laboratory Animals 46(2): 164-166, April 2012.

Friess SH, Smith C, Kilbaugh TJ, Frangos SG, Ralston J, Helfaer MA, Margulies SS: Early cerebral perfusion pressure augmentation with phenylephrine after traumatic brain injury may be neuroprotective in a pediatric swine model. Critical Care Medicine 40(8): 2400-2406, August 2012.

Stricker PA, Fiadjoe JE, Kilbaugh TJ, Pruitt EY, Taylor JA, Bartlett SP, McCloskey JJ: Effect of transfusion guidelines on postoperative transfusion in children undergoing craniofacial reconstruction surgery. Pediatric Critical Care Medicine 13(6): e357-e362, November 2012.

Hardesty DA, Kilbaugh TJ, Storm PB: Cerebral salt wasting syndrome in post-operative pediatric brain tumor patients. Neurocritical Care 17(3): 382-387, December 2012.

2011

Kilbaugh TJ, Bhandare S, Lorom DH, Saraswati M, Robertson CL, Margulies SS: Cyclosporin A preserves mitochondrial function after traumatic brain injury in the immature rat and piglet. Journal of Neurotrauma 28(5): 763-774, May 2011.

2010

Kilbaugh TJ, Friess SH, Raghupathi R, Huh JW: Sedation and analgesia in children with developmental disabilities and brain injury. International Journal of Pediatrics Page: 1-9, 2010.

2001

Serrano MS, Schmidt-Sommerfeld E, Kilbaugh TJ, Udall J, Brown R, Mannick B: The use of infiximab in the treatment of refractory Crohn's disease and ulcerative colitis in pediatric and adolescent patients. Annals of Pharmacotherapy 35(7-8): 823-828, July-August 2001.

2025

Herrmann J, Morgan RW, Starr J, Ko T, Senthil K, Jang DH, Kilbaugh TJ: Hippocampal Mitochondrial Dysfunction Persists for 7 Days in a Swine Pediatric Cardiac Arrest Model. Critical Care Congress February 2025 Notes: Presented at SCCM 2025, Orlando, Florida.

Patel B, Deshpande S, Katz AJ, Magee P, Mazandi VM, Corcoran A, Keim GP, Himebauch AS, Kilbaugh TJ, Hedrick H, Phinizy P, Daou AW, Piccione J, Senthil K: Endobronchial Valves for Pediatric Air-Leak Syndrome to Liberalize From Extracorporeal Support. Critical Care Congress February 2025 Notes: Presented at SCCM 2025, Orlando, Florida.

Zuckerberg J, Weeks KK, Widmann N, Ko T, Gaudio H, Eduardo L, Kienzle M, Berg R, Kilbaugh TJ, Morgan RW: Evaluation of Coronary Perfusion Pressure Calculation Methods During Cardiopulmonary Resuscitation. Critical Care Congress February 2025 Notes: Presented at SCCM 2025, Orlando, Florida.

2024

Chalifoux N, Ko T, Slovis J, Spelde A, Kilbaugh T, Mavroudis CD: Cerebral Autoregulation: A Target for Improving Neurological Outcomes in Extracorporeal Life Support. Neurocritical Care Online ahead of print, May 2024.

2022

Keim G, Himebauch AS, Yehya N, Slovis JC, Kilbaugh TJ, Stinson HR, Chiotos K, Morgan RW: Abandon Noninvasive Ventilation in Bronchiolitis? How Unrecognized Bias Can Lead to Problematic Conclusions. Crit Care Med 50(7): e653-e654e, July 2022.

Bruins BB, Kilbaugh TJ, Weintraub AY: Endocrine Disorders. Smith's Anesthesia for Infants and Children, 10th Edition. Davis PJ, Cladis FP (eds.). Page: 1199, 2022.

2021

Ko TS, Mavroudis CD, Morgan RW, Baker WB, Marquez AM, Boorady TW, Devarajan M, Lin Y, Roberts AL, Landis WP, Mensah-Brown K, Nadkarni VM, Berg RA, Sutton RM, Yodh AG, Licht DJ, Guo W, Kilbaugh TJ: Non-invasive diffuse optical neuromonitoring during cardiopulmonary resuscitation predicts return of spontaneous circulation. Scientific Report 11(1): 3828, February 2021. PMCID: PMC7884428

Mavroudis CD, Morgan RW, Berg RA, Kilbaugh TJ: "Authors' response" Critical Care 25(67), February 2021 Notes: Letter.

Slovis JC, Morgan RW, Kilbaugh TJ, Berg RA: Adrenaline effects on cerebral physiology during cardiac arrest: more to this story. Resuscitation 168: 216-218, November 2021 Notes: Editorial.

Bruins BB, Laverriere EK, Kilbaugh TJ: Chapter 11: Anesthesia consideration for flexible bronchoscopy. Diagnostic and Interventional Bronchoscopy in Children. Goldfarb S, Piccione J (eds.). Springer Nature, Page: 131-135, 2021 Notes: https://doi.org/10.1007/978-3-030-54924-4_11

Slovis JC, Morgan RW, Kilbaugh TJ, Berg RA.: Adrenaline effects on cerebral physiology during cardiac arrest: More to this story. Resuscitation 2021.

2020

Khaw KL, Sridharan A, Poznick L, Kilbaugh TJ, Hwang M: Probe position sensor to track image location in 2D ultrasound. Ultrasonics 103: 106084, February 2020.

Kilbaugh TJ, Sutton RM, Morgan RW, Topjian AA, Nadkarni VM, Berg RA: Chapter 13: Cardiopulmonary Resuscitation. Gregory's Pediatric Anesthesia. Dean B. Andropoulos, George A. Gregory, 6th Edition (eds.). Wiley-Blackwell, Page: 276-297, May 2020.

Shin SS, Karlsson M, Mazandi VM, Ranganathan A, Hallowell T, Delso N, Kilbaugh TJ: Axonal transport dysfunction of mitochondria in traumatic brain injury: A novel therapeutic target. Experimental Neurology 329: 113311, July 2020.

Mavroudis CD, Ko TS, Morgan RW, Volk LE, Landis WP, Smood B, Xiao R, Hefti M, Boorady TW, Marquez A, Karlsson M, Licht DJ, Nadkarni VM, Berg RA, Sutton RM, Kilbaugh TJ: Epinephrine's effects on cerebrovascular and systemic hemodynamics during

Kilbaugh TJ, Morgan RW, Berg RA: The neurologic impact of epinephrine during cardiac arrest: Much to learn Resuscitation 156: 263-264, November 2020 Notes: Editorial.

Kochanek PM, Jackson TC, Jha RM, Clark RSB, Okonkwo DO, Bayır H, Poloyac SM, Wagner AK, Empey PE, Conley YP, Bell MJ, Kline AE, Bondi CO, Simon DW, Carlson SW, Puccio AM, Horvat CM, Au AK, Elmer J, Treble-Barna A, Ikonomovic MD, Shutter LA, Taylor DL, Stern AM, Graham SH, Kagan VE, Jackson EK, Wisniewski SR, Dixon CE: Paths to Successful Translation of New Therapies for Severe Traumatic Brain Injury in the Golden Age of Traumatic Brain Injury Research: A Pittsburgh Vision. J Neurotrauma 37(22): 2353-2371, November 2020.

Bruins BB, Kilbaugh TJ: Challenges During Cranial Decompression. Essentials of Neurosurgical Anesthesia & Critical Care. Brambrink AM, Kirsch J (eds.). Springer, New York, NY, Page: 383-387, 2020.

Bruins BB, Kilbaugh TJ: Anatomy and Physiology of the Central Nervous System in Children. Essentials of Neurosurgical Anesthesia & Critical Care. Brambrink AM, Kirsch J (eds.). Springer, New York, NY, Page: 339-342, 2020.

2017

Morgan RW, Kilbaugh TJ: Optimal arterial carbon dioxide tension following cardiac arrest: Let Goldilocks decide? Resuscitation 111: A1-A2, February 2017 Notes: Editorial.

Heuer GG, Kilbaugh TJ, Huh JW: Acute Head Trauma. Fundamentals of Pediatric Surgery: Springer; 2017. p. 129-37. Mattei P, Nichol PF, Rollins,II MD, Muratore CS (eds.). Springer, New York, NY, Page: 129-137, 2017.

2016

Huh JW, Lang S, Kilbaugh TJ: Craniectomy for Traumatic Intracranial Hypertension. The New England Journal of Medicine 375(24): 2401-2404, December 2016.

2015

Kilbaugh TJ: Best Practices in the Management of Traumatic Brain Injury. American College of Surgeons Trauma Quality Improvement Program Page: 1-29, July 2015 Notes: This is an online guideline statement from the American College of Surgeons.

Kilbaugh TJ, Sutton RM, Karisson M, Hansson MJ, Naim MY, Morgan RW, Bratinov G, Lampe JW, Nadkarni VM, Becker LB, Margulies S, Berg RA: Persistently altered brain mitochondrial bioenergetics after apparently successful resuscitation from cardiac arrest. Journal of the American Heart Association 4(9): e002232, September 2015.

Lockman JL, Kilbaugh TJ: Recent Advances in Pediatric Monitoring Devices (Chapter). Current Concepts in Pediatric Critical Care. Graciano AL, Turner D (eds.). Society of Critical Care Medicine, Page: 13-22, 2015 Notes: 2015 Edition.

2014

Kilbaugh TJ, Zwass M, Ross P: Chapter 95: Pediatric and Neonatal Intensive Care. Miller's Anesthesia. Miller RD, (Cohen NJ, Eriksson LI, Fleisher LA, Weiner-Konish JP, Young WL (assoc eds), Vol 2: Eighth Edition (eds.). Saunders, Page: 2854-2923, 2014.

Stricker PA, Fiadjoe J, Kilbaugh TJ: Chapter 28: Pediatric Difficult Airway Management: Principles and Approach in the Critical Care Environment. Pediatric Critical Care Medicine: Vol. 1 Care of the Critically Ill or Injured Child. Wheeler DS, Wong HR, Shanley TP (eds.). Springer, Page: 329-343, 2014 Notes: 2nd Edition.

2013

Friess SH, Kilbaugh TJ, Huh J: Chapter 7: Traumatic brain injury. Pediatric Neurocritical Care. Abend NS, Helfaer MA (eds.). Demos Medical Publishing, LLC, Page: 103-116, 2013.

Kilbaugh TJ, Topjian AA, Friess SH: Chapter 4: Mechanical ventilation and blood pressure management. Pediatric Neurocritical Care. Abend NS, Helfaer MA (eds.). Demos Medical Publishing, LLC, Page: 65-80, 2013.

2012

Bruins BB, Kilbaugh TJ, Friess SH: Coagulopathy after pediatric traumatic brain injury: Association or causality? Pediatric Critical Care Medicine 13(4): 491-892, July 2012.

Friess SH, Kilbaugh TJ, Topjian AA: New tricks for an old dog: Multimodal neuromonitoring for DKA associated cerebral edema. Pediatric Critical Care Medicine 13(6): 702-703, November 2012 Notes: Editorial.

Friess SH, Kilbaugh TJ, Helfaer MA: Anatomy and physiology of the central nervous system in children. Essentials of Neurosurgical Anesthesia & Critical Care: Strategies for Prevention, Early Detection and Successful Management of Perioperative Complications. Brambrink A, Kirsch J (eds.). Springer Science, Page: 429-434, 2012.

Kilbaugh TJ, Friess SH, Helfaer MA: Challenges during cranial decompression. Essentials of Neurosurgical Anesthesia & Critical Care: Strategies for Prevention, Early Detection and Successful Management of Perioperative Complications. Brambrink A, Kirsch J (eds.). Springer Science, Page: 497-504, 2012.

Kilbaugh TJ, Topjian AA, Sutton RM, Nadkarni VM, Berg RA: Cardiopulmonary resuscitation. Gregory's Pediatric Anesthesia 5th Edition. Gregory GA, Andropoulos DB (eds.). Blackwell Publishing Ltd. Page: 255-272, 2012.

2011

Kilbaugh TJ, Huh JW, Berg RA: Neurologic injuries are major contributors to PICU deaths: A wake-up call. Pediatric Critical Care Medicine 12(5): 601-602, September 2011.

Heuer G, Fenning RS, Brown M, Kilbaugh TJ, Guzman MA, Judkins AR, Rorke-Adams L, Sutton L, Storm P: Pulmonary edema and cardiac dysfunction after resection of a fourth ventricle tumor in a toddler: Case Report. Childs Nervous System 27(11): 2005-2009, November 2011.

2010

Kilbaugh TJ, Srinivasan V, Berg RA, Nadkarni VM: Propensity, prophecy, and perplexity: does in-hospital extracorporeal cardiopulmonary resuscitation really make a difference? Resuscitation 81(7): 786-787, July 2010.

Kilbaugh TJ: Chapter 12: Respiratory Failure and Mechanical Ventilation. Surgical Directives: Fundamentals of Pediatric Surgery. Mattei P (eds.). Springer, Page: 83-91, 2010.

Kilbaugh TJ, McCloskey JM: Anterior Mediastinal Mass. Pediatric Critical Care: The Requisites. Helfaer MA (eds.). Elsevier, Page: 913-917, 2010.

2006

Augosustides J, Kilbaugh TJ, Harris H, Acker M, Savion J: Fatal thrombosis during mitral valve replacement for endocarditis: Aprotinin and disseminated intravascular coagulation. Anesthesiology 104(1): 213, January 2006.

Kilbaugh TJ, Huh JW, Helfaer MA: Disorders of temperature control. Current Pediatric Therapy. Gershon A (eds.). Saunders Elsevier, Page: 171-176, 2006.