Division of Orthopaedics Research

Researchers are studying ways in which Erg properties could be exploited therapeutically to maintain or restore function in injured or aging joints.

Researchers have created experimental models of hereditary multiple exostoses to study how exostoses form and grow, and are devising drug- and gene-based therapies to prevent exostosis formation. 

Researchers have identified a possible drug-based therapy for heterotopic ossification prevention and have tested it in experimental models of the disease.

Our orthopaedic clinical research evaluates treatments including spine deformities, bone tumors, trauma, sports medicine and a full range of orthopaedic abnormalities.

Our orthopaedic researchers combine laboratory and clinical research to create novel therapies that combine surgical and biologic tools.

Tendons and ligaments have limited repair capacity. Once damaged, tendons and ligaments undergo changes that cause substantial clinical problems including pain, swelling and local stiffness.

Clinicians at the Sports Medicine and Performance Center are actively involved in more than 30 current research projects and clinical trials.

Synovial joint formation researchers at CHOP focus on ways to harness the joint regenerative properties of certain cells and create new treatments.