Born with Poland syndrome, which caused his fingers to fuse together, Beau underwent surgery to give him the greatest possible function of his left hand.

Elijah needed a lifesaving surgery while he was still in his mother’s womb. Today, he's an active 6-year-old who loves basketball and T-ball, goes swimming, rides his bike, and rock climbs.

A unique program at CHOP allowed 7-year-old Isabella to attend school at the hospital while also getting radiation treatment for cancer.

Every day is a new adventure for Aidan, a 1-year-old with Down syndrome who embraces each new challenge with a smile on his face.

Diagnosed with severe allergic asthma, Lorenzo is no longer sitting on the sidelines. Thanks to biologic therapy at CHOP, he's back in the game.

Zach never let his spina bifida hold him back. He wants to make the world a better place and is raising money and awareness for the condition.

Bewildering symptoms, both physical and behavioral, brought Kayla to CHOP and led to a diagnosis of autoimmune encephalitis, a rare disease when a person’s immune system attacks their brain.

Born with a rare heart defect, Amelia received innovative, life-saving treatment at Children's Hospital of Philadelphia.

For years, Nora's family treated her severe asthma and food allergies as separate conditions, but a new biologic therapy at CHOP is improving both.

AJ’s life was relatively uncomplicated until age 14, when he began to experience unpredictable seizures and received a life-changing diagnosis of epilepsy. Thanks to the combination of a small, battery-powered device surgically implanted into his brain and an oral medication, he is now seizure-free.

Brayden struggled with severe constipation and encopresis for years before he got treatment to manage his condition at Children's Hospital of Philadelphia.

Kaitlyn lights up the room with her smile and emanates positivity, despite her battle with rhabdomyosarcoma.

Born with a backward heart on the wrong side of his chest, Matthew received a heart transplant and is now thriving.

Kaleo was diagnosed with juvenile myelomonocytic leukemia (JMML), a very rare form of cancer. One year after a bone marrow transplant, Kaleo is cancer-free.

Genetics experts at Children’s Hospital of Philadelphia have helped Cortney and Ryan identify their daughter’s rare genetic mutation, leading to improved care.

Diagnosed with Leber congenital amaurosis as a baby, Hannah was on a path to going blind until gene therapy at Children’s Hospital restored her sight.

Thanks to oral immunotherapy and the Food Allergy Bravery Clinic at CHOP, siblings PJ and Alana can now eat many of the foods that used to produce severe allergic reactions.

Diagnosed with autism as a toddler, Celi didn’t say her first word until she was 4. Today, at 14, she loves making art — and performing standup comedy.

Graves’ disease in young boys is rare. But that was the diagnosis for Kade, whose hyperthyroidism caused him to act out, and led his parents to seek treatment at CHOP.

A lifesaving treatment at CHOP gave Grace a chance at life, and her family hope for a future with their daughter.