Brenda L. Banwell, MD

Brenda L. Banwell, MD
Brenda L. Banwell, MD, is Chief of the Division of Neurology at Children's Hospital of Philadelphia and holder of the Grace R. Loeb Endowed Chair in Neurosciences.

Areas of Expertise: Pediatric multiple sclerosis, Inflammatory brain disorders, Acquired demyelinating diseases
Locations: Main Campus; Buerger Center for Advanced Pediatric Care

Background

Brenda L. Banwell, MD, is Chief of the Division of Neurology at the Children's Hospital of Philadelphia.

Dr. Banwell graduated with a degree in medicine from The University of Western Ontario in 1991. She pursued a residency in pediatrics at The Hospital of Western Ontario, University of Western Ontario, from 1991-1994 and a pediatric neurology residency at The Hospital for Sick Children, University of Toronto from 1994-1997. Dr. Banwell then spent two years completing a neuromuscular disease fellowship at the Mayo Clinic, Rochester, Minnesota. In 1999, Dr. Banwell was appointed as an assistant professor of paediatrics (neurology) at the Hospital for Sick Children and University of Toronto. She was promoted to associate professor in 2006 and full professor in 2012. As of July 1, 2012, Dr. Banwell has taken on the role of Chief of Neurology at the Children’s Hospital of Philadelphia.

Dr. Banwell’s clinical and research interests are in pediatric multiple sclerosis and other inflammatory brain disorders. She remains the lead investigator of the Canadian Pediatric Demyelinating Disease Program, which has now partnered with the pediatric demyelinating disease program in Philadelphia.

Here at CHOP, Dr. Banwell is the co-director of the Neuro-Immune and Multiple Sclerosis Program, a multidiscipline clinical and research program dedicated to children and adults with multiple sclerosis and other acquired demyelinating diseases. Her clinical studies focus on the cognitive and neuroimaging features of pediatric multiple sclerosis, while the basic science work focuses on T and B-cell autoimmunity studies, MRI imaging, and studies of viral triggers.

Dr. Banwell is the principal investigator of a 23-site, eight-year study of acute demyelination in children from every pediatric health care facility in Canada and now CHOP (funded by the Canadian Multiple Sclerosis Research Foundation and CHOP). She holds the National Multiple Sclerosis Society Grant, is the co-principal investigator of the PENN NeuroNEXT award  and has been successfully funded for over 17 years.

Dr. Banwell has more than 250 manuscripts published in high impact journals (including JAMA, Lancet Neurology and Nature Medicine), as well as over 25 book chapters. She has over 200 invited lectureships or visiting Professorships nationally and internationally.

Dr. Banwell cares deeply about the experience of children living with multiple sclerosis and related disorders and focuses her clinical time speaking to children and teenagers to ensure that their views are heard. Dr. Banwell advocates for pediatric multiple sclerosis needs and research, serving as the chair for the International Pediatric Multiple Sclerosis Study Group. Dr. Banwell has authored social media posts, brochures, and online materials for children and families and has participated in multiple podcasts discussing pediatric care for children with multiple sclerosis.

Education and Training

Medical School

MD - University of Western Ontario, London, Ontario

Internship

Pediatrics - University of Western Ontario-Children's Hospital of Western Ontario, London, Ontario

Residency

Pediatrics - University of Western Ontario-Children's Hospital of Western Ontario, London, Ontario
Pediatric Neurology - University of Toronto - The Hospital for Sick Children, Toronto, Ontario (Chief Resident)

Fellowship

Neuromuscular Research - Mayo Clinic, Rochester, MN

Board Certification

Neurology
Pediatrics

Titles and Academic Titles

Chief, Division of Neurology

Professor of Neurology, Perelman School of Medicine at the University of Pennsylvania

Conditions Treated

Departments and Services

Research Interests

Pediatric multiple sclerosis and other inflammatory brain disorders

Acute demyelination in children

Cognitive and neuroimaging features of pediatric multiple sclerosis

T and B-cell autoimmunity studies, MRI imaging, and studies of viral triggers in children with multiple sclerosis

Publications

Papers

2019

Maranzano J, Till C, Assemlal HE, Fonov V, Brown R, Araujo D, O'Mahony J, Yeh EA, Bar-Or A, Marrie RA, Collins L, Banwell B, Arnold DL, Narayanan S.  Detection and clinical correlation of leukocortical lesions in pediatric-onset multiple sclerosis on multi-contrast MRI. Mult Scler. 2019 Jun;25(7):980-986. doi: 10.1177/1352458518779952. Epub 2018 Jun 1. PubMed PMID: 29852831.

Waubant E, Banwell B, Wassmer E, Sormani MP, Amato MP, Hintzen R, Krupp L, Rostásy K, Tenembaum S, Chitnis T.  Clinical trials of disease-modifying agents in pediatric MS: Opportunities, challenges, and recommendations from the IPMSSG. Neurology. 2019 May 1;. doi: 10.1212/WNL.0000000000007572. [Epub ahead of print] PubMed PMID: 31043474.

Banwell B.  Are children with multiple sclerosis really "old" adults. Mult Scler. 2019 Apr 4;:1352458519841505. doi: 10.1177/1352458519841505. [Epub ahead of print] PubMed PMID: 30945591.

Lavery AM, Collins BN, Waldman AT, Hart CN, Bar-Or A, Marrie RA, Arnold D, O'Mahony J, Banwell B.  The contribution of secondhand tobacco smoke exposure to pediatric multiple sclerosis risk. Mult Scler. 2019 Apr;25(4):515-522. doi: 10.1177/1352458518757089. Epub 2018 Feb 2. PubMed PMID: 29393768.

Barlow-Krelina E, Turner GR, Akbar N, Banwell B, Lysenko M, Yeh EA, Narayanan S, Collins DL, Aubert-Broche B, Till C.  Enhanced Recruitment During Executive Control Processing in Cognitively Preserved Patients With Pediatric-Onset MS. J Int Neuropsychol Soc. 2019 Apr;25(4):432-442. doi: 10.1017/S135561771800125X. Epub 2019 Feb 28. PubMed PMID: 30813973.

Mexhitaj I, Nyirenda MH, Li R, O'Mahony J, Rezk A, Rozenberg A, Moore CS, Johnson T, Sadovnick D, Collins DL, Arnold DL, Gran B, Yeh EA, Marrie RA, Banwell B, Bar-Or A.  Abnormal effector and regulatory T cell subsets in paediatric-onset multiple sclerosis. Brain. 2019 Mar 1;142(3):617-632. doi: 10.1093/brain/awz017. PubMed PMID: 30759186; PubMed Central PMCID: PMC6391601.

Fadda G, Brown RA, Magliozzi R, Aubert-Broche B, O'Mahony J, Shinohara RT, Banwell B, Marrie RA, Yeh EA, Collins DL, Arnold DL, Bar-Or A.  A surface-in gradient of thalamic damage evolves in pediatric multiple sclerosis. Ann Neurol. 2019 Mar;85(3):340-351. doi: 10.1002/ana.25429. Epub 2019 Feb 20. PubMed PMID: 30719730. 

2018

Tantsis EM, Prelog K, Alper G, Benson L, Gorman M, Lim M, Mohammad SS, Ramanathan S, Brilot F, Dale RC.  Magnetic resonance imaging in enterovirus-71, myelin oligodendrocyte glycoprotein antibody, aquaporin-4 antibody, and multiple sclerosis-associated myelitis in children. Dev Med Child Neurol. 2018 Dec 10;. doi: 10.1111/dmcn.14114. [Epub ahead of print] PubMed PMID: 30537075. 

Longoni G, Brown RA, Aubert-Broche B, Grover SA, Branson HM, Fetco D, Bar-Or A, Marrie RA, Motl RW, Collins DL, Narayanan S, Arnold DL, Banwell B, Yeh EA.  Physical activity and dentate gyrus volume in pediatric acquired demyelinating syndromes. Neurol Neuroimmunol Neuroinflamm. 2018 Nov;5(6):e499. doi: 10.1212/NXI.0000000000000499. eCollection 2018 Nov. PubMed PMID: 30211252; PubMed Central PMCID: PMC6131051.

Marrie RA, O'Mahony J, Maxwell C, Ling V, Yeh EA, Arnold DL, Bar-Or A, Banwell B.  Incidence and prevalence of MS in children: A population-based study in Ontario, Canada. Neurology. 2018 Oct 23;91(17):e1579-e1590. doi: 10.1212/WNL.0000000000006395. Epub 2018 Sep 26. PubMed PMID: 30258022. 

Gofshteyn JS, Shaw PA, Teachey DT, Grupp SA, Maude S, Banwell B, Chen F, Lacey SF, Melenhorst JJ, Edmonson MJ, Panzer J, Barrett DM, McGuire JL.  Neurotoxicity after CTL019 in a pediatric and young adult cohort. Ann Neurol. 2018 Oct;84(4):537-546. doi: 10.1002/ana.25315. Epub 2018 Sep 26. PubMed PMID: 30178481; PubMed Central PMCID: PMC6444896.

Chitnis T, Arnold DL, Banwell B, Brück W, Ghezzi A, Giovannoni G, Greenberg B, Krupp L, Rostásy K, Tardieu M, Waubant E, Wolinsky JS, Bar-Or A, Stites T, Chen Y, Putzki N, Merschhemke M, Gärtner J.  Trial of Fingolimod versus Interferon Beta-1a in Pediatric Multiple Sclerosis. N Engl J Med. 2018 Sep 13;379(11):1017-1027. doi: 10.1056/NEJMoa1800149. PubMed PMID: 30207920. 

O'Mahony J, Marrie RA, Laporte A, Bar-Or A, Yeh EA, Brown A, Dilenge ME, Banwell B.  Pediatric-onset multiple sclerosis is associated with reduced parental health-related quality of life and family functioning. Mult Scler. 2018 Aug 30;:1352458518796676. doi: 10.1177/1352458518796676. [Epub ahead of print] PubMed PMID: 30160208. 

McNicholas N, Hutchinson M, McGuigan C, Chataway J. 2017 McDonald diagnostic criteria: A review of the evidence. Multiple sclerosis and related disorders. 2018; 24:48-54.

Wells E, Hacohen Y, Waldman A, Tillema JM, Soldatos A, Ances B, Benseler S, Bielekova B, Dale RC, Dalmau J, Gaillard W, Gorman M, Greenberg B, Hyslop A, Pardo CA, Tasker RC, Yeh EA, Bar-Or A, Pittock S, Vanderver A, Banwell B. Neuroimmune disorders of the central nervous system in children in the molecular era. Nature reviews. Neurology. 2018;

Green R, Adler A, Banwell BL, Fabri TL, Yeh EA, Collins DL, Sled JG, Narayanan S, Till C. Involvement of the Amygdala in Memory and Psychosocial Functioning in Pediatric-Onset Multiple Sclerosis. Developmental neuropsychology. 2018; :1-11.

Parmar K, Banwell BL, Akbar N, Bigi S. Imaging Pediatric Multiple Sclerosis-Challenges and Recent Advances. Neuropediatrics. 2018; 49(3):165-172.

Magalhaes S, Banwell B, Bar-Or A, Fortier I, Hanwell HE, Lim M, Matt GE, Neuteboom RF, O'Riordan DL, Schneider PK, Pugliatti M, Shatenstein B, Tansey CM, Wassmer E, Wolfson C. A framework for measurement and harmonization of pediatric multiple sclerosis etiologic research studies: The Pediatric MS Tool-Kit. Multiple sclerosis (Houndmills, Basingstoke, England). 2018; :1352458518783345.

Maranzano J, Till C, Assemlal HE, Fonov V, Brown R, Araujo D, O'Mahony J, Yeh EA, Bar-Or A, Marrie RA, Collins L, Banwell B, Arnold DL, Narayanan S. Detection and clinical correlation of leukocortical lesions in pediatric-onset multiple sclerosis on multi-contrast MRI. Multiple sclerosis (Houndmills, Basingstoke, England). 2018; :1352458518779952.

Yeh EA, Grover SA, Powell VE, Alper G, Banwell BL, Edwards K, Gorman M, Graves J, Lotze TE, Mah JK, Mednick L, Ness J, Obadia M, Slater R, Waldman A, Waubant E, Schwartz CE. Correction to: Impact of an electrnic monitoring device and behavioural feedback on adherence to multiple sclerosis therapies in youth: results of a randomized trial. Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation. 2018; 27(4):1117.

Brenton JN, Schreiner T, Karoscik K, Richter M, Ferrante S, Waldman A, Banwell B. Attitudes, perceptions, and use of marijuana in youth with multiple sclerosis. Journal of neurology. 2018; 265(2):417-423.

Schwartz CE, Grover SA, Powell VE, Noguera A, Mah JK, Mar S, Mednick L, Banwell BL, Alper G, Rensel M, Gorman M, Waldman A, Schreiner T, Waubant E, Yeh EA. Risk factors for non-adherence to disease-modifying therapy in pediatric multiple sclerosis. Multiple sclerosis (Houndmills, Basingstoke, England). 2018; 24(2):175-185.

Lavery AM, Collins BN, Waldman AT, Hart CN, Bar-Or A, Marrie RA, Arnold D, O'Mahony J, Banwell B. The contribution of secondhand tobacco smoke exposure to pediatric multiple sclerosis risk. Multiple sclerosis (Houndmills, Basingstoke, England). 2018; :1352458518757089.

2017

Baskin B, Kalia LV, Banwell BL, Ray PN, Yoon G. Complex genomic rearrangement in SPG11 due to a DNA replication-based mechanism. Movement disorders : official journal of the Movement Disorder Society. 2017; 32(12):1792-1794.

Banwell B, Marrie RA. Increased relapse rate during pregnancy and postpartum in neuromyelitis optica. Neurology. 2017; 89(22):2220-2221.

Scolding NJ, Pasquini M, Reingold SC, Cohen JA. Cell-based therapeutic strategies for multiple sclerosis. Brain : a journal of neurology. 2017; 140(11):2776-2796.

Abath Neto O, Moreno CAM, Malfatti E, Donkervoort S, Böhm J, Guimarães JB, Foley AR, Mohassel P, Dastgir J, Bharucha-Goebel DX, Monges S, Lubieniecki F, Collins J, Medne L, Santi M, Yum S, Banwell B, Salort-Campana E, Rendu J, Fauré J, Yis U, Eymard B, Cheraud C, Schneider R, Thompson J, Lornage X, Mesrob L, Lechner D, Boland A, Deleuze JF, Reed UC, Oliveira ASB, Biancalana V, Romero NB, Bönnemann CG, Laporte J, Zanoteli E. Common and variable clinical, histological, and imaging findings of recessive RYR1-related centronuclear myopathy patients. Neuromuscular disorders : NMD. 2017; 27(11):975-985.

Gordon-Lipkin E, Banwell B. An update on multiple sclerosis in children: diagnosis, therapies, and prospects for the future. Expert review of clinical immunology. 2017; 13(10):975-989.

Ortiz-Gonzalez X, Goldberg EM, Banwell B. Obituary: Jessica Anne Panzer, MD, PhD. Pediatric neurology. 2017; 75:4-5.

Till C, Kuni B, De Somma E, Yeh EA, Banwell B. A feasibility study of working memory training for individuals with paediatric-onset multiple sclerosis. Neuropsychological rehabilitation. 2017; :1-16.

Akbar N, Signori A, Amato MP, Sormani MP, Portaccio E, Niccolai C, Goretti B, Till C, Banwell B. Maturational Trajectory of Processing Speed Performance in Pediatric Multiple Sclerosis. Developmental neuropsychology. 2017; 42(5):299-308.

Datta R, Sethi V, Ly S, Waldman AT, Narula S, Dewey BE, Sati P, Reich D, Banwell B. 7T MRI Visualization of Cortical Lesions in Adolescents and Young Adults with Pediatric-Onset Multiple Sclerosis. Journal of neuroimaging: official journal of the American Society of Neuroimaging. 2017; 27(5):447-452. NIHMSID: NIHMS894813

Yeh EA, Grover SA, Powell VE, Alper G, Banwell BL, Edwards K, Gorman M, Graves J, Lotze TE, Mah JK, Mednick L, Ness J, Obadia M, Slater R, Waldman A, Waubant E, Schwartz CE. Impact of an electronic monitoring device and behavioral feedback on adherence to multiple sclerosis therapies in youth: results of a randomized trial. Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation. 2017; 26(9):2333-2349.

Corwin DJ, Topjian A, Banwell BL, Osterhoudt K. Adverse events associated with a large dose of intravenous lipid emulsion for suspected local anesthetic toxicity. Clinical toxicology (Philadelphia, Pa.). 2017; 55(6):603-607.

Waldman AT, Liu GT, Lavery AM, Liu G, Gaetz W, Aleman TS, Banwell BL. Optical coherence tomography and visual evoked potentials in pediatric MS. Neurology(R) neuroimmunology & neuroinflammation. 2017; 4(4):e356.

Yeshokumar AK, Narula S, Banwell B. Pediatric multiple sclerosis. Current opinion in neurology. 2017; 30(3):216-221.

Aubert-Broche B, Weier K, Longoni G, Fonov VS, Bar-Or A, Marrie RA, Yeh EA, Narayanan S, Arnold DL, Verhey LH, Banwell B, Collins DL. Monophasic demyelination reduces brain growth in children. Neurology. 2017; 88(18):1744-1750.

Longoni G, Brown RA, MomayyezSiahkal P, Elliott C, Narayanan S, Bar-Or A, Marrie RA, Yeh EA, Filippi M, Banwell B, Arnold DL. White matter changes in paediatric multiple sclerosis and monophasic demyelinating disorders. Brain: a journal of neurology. 2017; 140(5):1300-1315.

Bigi S, Marrie RA, Till C, Yeh EA, Akbar N, Feinstein A, Banwell BL. The computer-based Symbol Digit Modalities Test: establishing age-expected performance in healthy controls and evaluation of pediatric MS patients. Neurological sciences: official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology. 2017; 38(4):635-642.

Lin JJ, Banwell BL, Berg RA, Dlugos DJ, Ichord RN, Kilbaugh TJ, Kirsch RE, Kirschen MP, Licht DJ, Massey SL, Naim MY, Rintoul NE, Topjian AA, Abend NS. Electrographic Seizures in Children and Neonates Undergoing Extracorporeal Membrane Oxygenation. Pediatric critical care medicine: a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies. 2017; 18(3):249-257. NIHMSID: NIHMS829174

Banwell B. Paediatric neurology in 2016: a year in review. The Lancet. Neurology. 2017; 16(1):14-15.

2016

Siegler JE, Banwell B, Ichord RN. Teaching NeuroImages: Intracranial vertebral dissection in a 15-year-old boy with sickle cell disease. Neurology. 2016; 87(24):e290-e291.

Grover SA, Sawicki CP, Kinnett-Hopkins D, Finlayson M, Schneiderman JE, Banwell B, Till C, Motl RW, Yeh EA. Physical Activity and Its Correlates in Youth with Multiple Sclerosis. The Journal of pediatrics. 2016; 179:197-203.e2.

Waldman AT, Chahin S, Lavery AM, Liu G, Banwell BL, Liu GT, Balcer LJ. Binocular low-contrast letter acuity and the symbol digit modalities test improve the ability of the Multiple Sclerosis Functional Composite to predict disease in pediatric multiple sclerosis. Multiple sclerosis and related disorders. 2016; 10:73-78.

Till C, Noguera A, Verhey LH, O'Mahony J, Yeh EA, Mah JK, Sinopoli KJ, Brooks BL, Aubert-Broche B, Collins DL, Narayanan S, Arnold DL, Banwell BL. Cognitive and Behavioral Functioning in Childhood Acquired Demyelinating Syndromes. Journal of the International Neuropsychological Society : JINS. 2016; 22(10):1050-1060.

Banwell B. Clinical trials for pediatric MS should be prioritized to test only one or two of the most promising agents - YES. Multiple sclerosis (Houndmills, Basingstoke, England). 2016; 22(13):1649-1651.

Al-Maawali A, Yoon G, Feigenbaum AS, Halliday WC, Clarke JT, Branson HM, Banwell BL, Chitayat D, Blaser SI. Validation of the finding of hypertrophy of the clava in infantile neuroaxonal dystrophy/PLA2G6 by biometric analysis. Neuroradiology. 2016; 58(10):1035-1042.

Lavery AM, Banwell BL, Liu G, Waldman AT. Hospital admission rates for pediatric multiple sclerosis in the United States using the Pediatric Health Information System (PHIS). Multiple sclerosis and related disorders. 2016; 9:5-10.

Weier K, Fonov V, Aubert-Broche B, Arnold DL, Banwell B, Collins DL. Impaired growth of the cerebellum in pediatric-onset acquired CNS demyelinating disease. Multiple sclerosis (Houndmills, Basingstoke, England). 2016; 22(10):1266-78.

Banwell B, Arnold DL, Tillema JM, Rocca MA, Filippi M, Weinstock-Guttman B, Zivadinov R, Sormani MP. MRI in the evaluation of pediatric multiple sclerosis. Neurology. 2016; 87(9 Suppl 2):S88-96.

Tardieu M, Banwell B, Wolinsky JS, Pohl D, Krupp LB. Consensus definitions for pediatric MS and other demyelinating disorders in childhood. Neurology. 2016; 87(9 Suppl 2):S8-S11.

Hintzen RQ, Dale RC, Neuteboom RF, Mar S, Banwell B. Pediatric acquired CNS demyelinating syndromes: Features associated with multiple sclerosis. Neurology. 2016; 87(9 Suppl 2):S67-73.

Wassmer E, Chitnis T, Pohl D, Amato MP, Banwell B, Ghezzi A, Hintzen RQ, Krupp LB, Makhani N, Rostásy K, Tardieu M, Tenembaum S, Waldman A, Waubant E, Kornberg AJ. International Pediatric MS Study Group Global Members Symposium report. Neurology. 2016; 87(9 Suppl 2):S110-6.

Schiffmann R, Banwell B. Brain MRI and motor function in leukodystrophies. Schiffmann R, Banwell B. Neurology. 2016; 87(8):748-9.

Banwell B. Pediatric multiple sclerosis: The 2015 Sydney Carter Award Lecture. Neurology. 2016; 87(8):822-6.

Narula S, Banwell B. Pediatric Demyelination. Continuum (Minneapolis, Minn.). 2016; 22(3):897-915.

Banwell B, Giovannoni G, Hawkes C, Lublin F. Editors' Welcome. Multiple sclerosis and related disorders. 2016; 7:A1-2.Williams RP, Banwell B, Berg RA, Dlugos DJ, Donnelly M, Ichord R, Kessler SK, Lavelle J, Massey SL, Hewlett J, Parker A, Topjian AA, Abend NS. Impact of an ICU EEG monitoring pathway on timeliness of therapeutic intervention and electrographic seizure termination. Epilepsia. 2016; 57(5):786-95.

Akbar N, Till C, Sled JG, Binns MA, Doesburg SM, Aubert-Broche B, Collins DL, Araujo D, Narayanan S, Arnold DL, Lysenko M, Banwell B. Altered resting-state functional connectivity in cognitively preserved pediatric-onset MS patients and relationship to structural damage and cognitive performance. Multiple sclerosis (Houndmills, Basingstoke, England). 2016; 22(6):792-800.

Krupp LB, Pohl D, Ghezzi A, Boyko A, Tenembaum S, Chen L, Aycardi E, Banwell B. Subcutaneous interferon β-1a in pediatric patients with multiple sclerosis: Regional differences in clinical features, disease management, and treatment outcomes in an international retrospective study. Journal of the neurological sciences. 2016; 363:33-8.

Marrie RA, Miller A, Sormani MP, Thompson A, Waubant E, Trojano M, O'Connor P, Reingold S, Cohen JA. The challenge of comorbidity in clinical trials for multiple sclerosis. Neurology. 2016; 86(15):1437-45.

Marrie RA, Miller A, Sormani MP, Thompson A, Waubant E, Trojano M, O'Connor P, Fiest K, Reider N, Reingold S, Cohen JA. Recommendations for observational studies of comorbidity in multiple sclerosis. Neurology. 2016; 86(15):1446-53.

Gmuca S, Boos MD, Treece A, Narula S, Billinghurst L, Bhatti T, Laje P, Perman MJ, Vossough A, Harding B, Burnham J, Banwell B. Degos disease mimicking primary vasculitis of the CNS. Neurology(R) neuroimmunology & neuroinflammation. 2016; 3(2):e206.

Weier K, Till C, Fonov V, Yeh EA, Arnold DL, Banwell B, Collins DL. Contribution of the cerebellum to cognitive performance in children and adolescents with multiple sclerosis. Multiple sclerosis (Houndmills, Basingstoke, England). 2016; 22(5):599-607.

Rocca MA, Sonkin M, Copetti M, Pagani E, Arnold DL, Narayanan S, Sled JG, Banwell B, Filippi M. Diffusion tensor magnetic resonance imaging in very early onset pediatric multiple sclerosis. Multiple sclerosis (Houndmills, Basingstoke, England). 2016; 22(5):620-7.

Banwell B, Giovannoni G, Hawkes C, Lublin F. Editors' Welcome. Multiple sclerosis and related disorders. 2016; 6:A1-2.

Makhani N, Banwell B, Tellier R, Yea C, McGovern S, O'Mahony J, Ahorro JM, Arnold D, Sadovnick AD, Marrie RA, Bar-Or A. Viral exposures and MS outcome in a prospective cohort of children with acquired demyelination. Multiple sclerosis (Houndmills, Basingstoke, England). 2016; 22(3):385-8.

Filippi M, Rocca MA, Ciccarelli O, De Stefano N, Evangelou N, Kappos L, Rovira A, Sastre-Garriga J, Tintorè M, Frederiksen JL, Gasperini C, Palace J, Reich DS, Banwell B, Montalban X, Barkhof F. MRI criteria for the diagnosis of multiple sclerosis: MAGNIMS consensus guidelines. The Lancet. Neurology. 2016; 15(3):292-303.

Nosadini M, Alper G, Riney CJ, Benson LA, Mohammad SS, Ramanathan S, Nolan M, Appleton R, Leventer RJ, Deiva K, Brilot F, Gorman MP, Waldman AT, Banwell B, Dale RC. Rituximab monitoring and redosing in pediatric neuromyelitis optica spectrum disorder. Neurology(R) neuroimmunology & neuroinflammation. 2016; 3(1):e188.

Akbar N, Giorgio A, Till C, Sled JG, Doesburg SM, De Stefano N, Banwell B. Alterations in Functional and Structural Connectivity in Pediatric-Onset Multiple Sclerosis. PloS one. 2016; 11(1):e0145906.

Akbar N, Banwell B, Sled JG, Binns MA, Doesburg SM, Rypma B, Lysenko M, Till C. Brain activation patterns and cognitive processing speed in patients with pediatric-onset multiple sclerosis. Journal of clinical and experimental neuropsychology. 2016; 38(4):393-403.

Brenton JN, Banwell BL. Therapeutic Approach to the Management of Pediatric Demyelinating Disease: Multiple Sclerosis and Acute Disseminated Encephalomyelitis. Neurotherapeutics: the journal of the American Society for Experimental NeuroTherapeutics. 2016; 13(1):84-95.

Banwell B, Giovannoni G, Hawkes C, Lublin F. Editors' Welcome. Multiple sclerosis and related disorders. 2016; 5:A1.

2015

Grover SA, Aubert-Broche B, Fetco D, Collins DL, Arnold DL, Finlayson M, Banwell BL, Motl RW, Yeh EA. Lower physical activity is associated with higher disease burden in pediatric multiple sclerosis. Neurology. 2015; 85(19):1663-9.

Banwell B, Giovannoni G, Hawkes C, Lublin F. Editors' Welcome. Multiple sclerosis and related disorders. 2015; 4(6):A1-2.

Lucas RM, Banwell B. Do prenatal sex hormones modulate MS risk? Neurology. 2015; 85(14):1193-4.

Banwell B, Giovannoni G, Hawkes C, Lublin F. Editors' Welcome. Multiple sclerosis and related disorders. 2015; 4(5):A1-A2.

Melamed E, Levy M, Waters PJ, Sato DK, Bennett JL, John GR, Hooper DC, Saiz A, Bar-Or A, Kim HJ, Pandit L, Leite MI, Asgari N, Kissani N, Hintzen R, Marignier R, Jarius S, Marcelletti J, Smith TJ, Yeaman MR, Han MH, Aktas O, Apiwattanakul M, Banwell B, Bichuetti D, Broadley S, Cabre P, Chitnis T, De Seze J, Fujihara K, Greenberg B, Hellwig K, Iorio R, Jarius S, Klawiter E, Kleiter I, Lana-Peixoto M, Nakashima, O'Connor K, Palace J, Paul F, Prayoonwiwat N, Ruprecht K, Stuve O, Tedder T, Tenembaum S, Garrahan JP, Aires B, van Herle K, van Pelt D, Villoslada P, Waubant E, Weinshenker B, Wingerchuk D, Würfel J, Zamvil S. Update on biomarkers in neuromyelitis optica. Neurology(R) neuroimmunology & neuroinflammation. 2015; 2(4):e134.

Wingerchuk DM, Banwell B, Bennett JL, Cabre P, Carroll W, Chitnis T, de Seze J, Fujihara K, Greenberg B, Jacob A, Jarius S, Lana-Peixoto M, Levy M, Simon JH, Tenembaum S, Traboulsee AL, Waters P, Wellik KE, Weinshenker BG. International consensus diagnostic criteria for neuromyelitis optica spectrum disorders. Neurology. 2015; 85(2):177-89.

O'Mahony J, Marrie RA, Laporte A, Yeh EA, Bar-Or A, Phan C, Buckley D, Callen D, Connolly MB, Pohl D, Dilenge ME, Bernard G, Lortie A, Lowry N, MacDonald EA, Meek D, Sébire G, Venkateswaran S, Wood E, Yager J, Banwell B. Recovery From Central Nervous System Acute Demyelination in Children. Pediatrics. 2015; 136(1):e115-23.

Kremer S, Renard F, Achard S, Lana-Peixoto MA, Palace J, Asgari N, Klawiter EC, Tenembaum SN, Banwell B, Greenberg BM, Bennett JL, Levy M, Villoslada P, Saiz A, Fujihara K, Chan KH, Schippling S, Paul F, Kim HJ, de Seze J, Wuerfel JT, Cabre P, Marignier R, Tedder T, van Pelt D, Broadley S, Chitnis T, Wingerchuk D, Pandit L, Leite MI, Apiwattanakul M, Kleiter I, Prayoonwiwat N, Han M, Hellwig K, van Herle K, John G, Hooper DC, Nakashima I, Sato D, Yeaman MR, Waubant E, Zamvil S, Stüve O, Aktas O, Smith TJ, Jacob A, O'Connor K. Use of Advanced Magnetic Resonance Imaging Techniques in Neuromyelitis Optica Spectrum Disorder. JAMA neurology. 2015; 72(7):815-22.

Banwell B, Giovannoni G, Hawkes C, Lublin F. Editors' Welcome. Multiple sclerosis and related disorders. 2015; 4(4):A1-3.

Weier K, Banwell B, Cerasa A, Collins DL, Dogonowski AM, Lassmann H, Quattrone A, Sahraian MA, Siebner HR, Sprenger T. The role of the cerebellum in multiple sclerosis. Cerebellum (London, England). 2015; 14(3):364-74.

Bigi S, Banwell B, Yeh EA. Outcomes after early administration of plasma exchange in pediatric central nervous system inflammatory demyelination. Journal of child neurology. 2015; 30(7):874-80.

Ahn JJ, O'Mahony J, Moshkova M, Hanwell HE, Singh H, Zhang MA, Marrie RA, Bar-Or A, Sadovnick DA, Dunn SE, Banwell BL. Puberty in females enhances the risk of an outcome of multiple sclerosis in children and the development of central nervous system autoimmunity in mice. Multiple sclerosis (Houndmills, Basingstoke, England). 2015; 21(6):735-48.

Ghassemi R, Brown R, Banwell B, Narayanan S, Arnold DL. Quantitative Measurement of tissue damage and recovery within new T2w lesions in pediatric- and adult-onset multiple sclerosis. Multiple sclerosis (Houndmills, Basingstoke, England). 2015; 21(6):718-25.

Bennett JL, de Seze J, Lana-Peixoto M, Palace J, Waldman A, Schippling S, Tenembaum S, Banwell B, Greenberg B, Levy M, Fujihara K, Chan KH, Kim HJ, Asgari N, Sato DK, Saiz A, Wuerfel J, Zimmermann H, Green A, Villoslada P, Paul F. Neuromyelitis optica and multiple sclerosis: Seeing differences through optical coherence tomography. Multiple sclerosis (Houndmills, Basingstoke, England). 2015; 21(6):678-88.

Banwell B, Giovannoni G, Hawkes C, Lublin F. Editors' welcome. Multiple sclerosis and related disorders. 2015; 4(3):181.

Sham L, Yeh EA, Magalhaes S, Parra EJ, Gozdzik A, Banwell B, Hanwell HE. Evaluation of fall Sun Exposure Score in predicting vitamin D status in young Canadian adults, and the influence of ancestry. Journal of photochemistry and photobiology. B, Biology. 2015; 145:25-9.

Narula S, Banwell B. Treatment of multiple sclerosis in children and its challenges. Presse medicale (Paris, France : 1983). 2015; 44(4 Pt 2):e153-8.

Narula S, Liu GT, Avery RA, Banwell B, Waldman AT. Elevated cerebrospinal fluid opening pressure in a pediatric demyelinating disease cohort. Pediatric neurology. 2015; 52(4):446-9.

Banwell B, Giovannoni G, Hawkes C, Lublin F. Editors' welcome. Multiple sclerosis and related disorders. 2015; 4(2):93-4.

Kim HJ, Paul F, Lana-Peixoto MA, Tenembaum S, Asgari N, Palace J, Klawiter EC, Sato DK, de Seze J, Wuerfel J, Banwell BL, Villoslada P, Saiz A, Fujihara K, Kim SH. MRI characteristics of neuromyelitis optica spectrum disorder: an international update. Neurology. 2015; 84(11):1165-73.

Narula S, Hopkins SE, Banwell B. Treatment of pediatric multiple sclerosis. Current treatment options in neurology. 2015; 17(3):336.

Ghassemi R, Brown R, Narayanan S, Banwell B, Nakamura K, Arnold DL. Normalization of white matter intensity on T1-weighted images of patients with acquired central nervous system demyelination. Journal of neuroimaging: official journal of the American Society of Neuroimaging. 2015; 25(2):184-190.

Banwell B, Dale RC. Understanding risk of relapse and risk of disability after childhood transverse myelitis. Neurology. 2015; 84(4):332-4.

Banwell B, Giovannoni G, Hawkes C, Lublin F. Editors׳ welcome. Multiple sclerosis and related disorders. 2015; 4(1):1-2.

Varsani H, Charman SC, Li CK, Marie SK, Amato AA, Banwell B, Bove KE, Corse AM, Emslie-Smith AM, Jacques TS, Lundberg IE, Minetti C, Nennesmo I, Rushing EJ, Sallum AM, Sewry C, Pilkington CA, Holton JL, Wedderburn LR. Validation of a score tool for measurement of histological severity in juvenile dermatomyositis and association with clinical severity of disease. Annals of the rheumatic diseases. 2015; 74(1):204-10. 

2014

Longoni G, Banwell B, Filippi M, Yeh EA. Rituximab as a first-line preventive treatment in pediatric NMOSDs: Preliminary results in 5 children. Neurology(R) neuroimmunology & neuroinflammation. 2014; 1(4):e46.

Quintana FJ, Patel B, Yeste A, Nyirenda M, Kenison J, Rahbari R, Fetco D, Hussain M, O'Mahony J, Magalhaes S, McGowan M, Johnson T, Rajasekharan S, Narayanan S, Arnold DL, Weiner HL, Banwell B, Bar-Or A. Epitope spreading as an early pathogenic event in pediatric multiple sclerosis. Neurology. 2014; 83(24):2219-26.

Aubert-Broche B, Fonov V, Narayanan S, Arnold DL, Araujo D, Fetco D, Till C, Sled JG, Banwell B, Collins DL. Onset of multiple sclerosis before adulthood leads to failure of age-expected brain growth. Neurology. 2014; 83(23):2140-6.

Yeh EA, Marrie RA, Reginald YA, Buncic JR, Noguera AE, O'Mahony J, Mah JK, Banwell B, Costello F. Functional-structural correlations in the afferent visual pathway in pediatric demyelination. Neurology. 2014; 83(23):2147-52.

Banwell B, Giovannoni G, Hawkes C, Lublin F. Editors' welcome. Multiple sclerosis and related disorders. 2014; 3(6):667.

Bigi S, Marrie R, Yeh E, Banwell B. Antinuclear antibodies in pediatric acquired demyelinating diseases of the central nervous system. Multiple sclerosis (Houndmills, Basingstoke, England). 2014; 20(12):1665-6.

Brown RA, Narayanan S, Banwell B, Arnold DL. Magnetization transfer ratio recovery in new lesions decreases during adolescence in pediatric-onset multiple sclerosis patients. NeuroImage. Clinical. 2014; 6:237-42.

Hosseini B, Flora DB, Banwell BL, Till C. Age of onset as a moderator of cognitive decline in pediatric-onset multiple sclerosis. Journal of the International Neuropsychological Society : JINS. 2014; 20(8):796-804.

Banwell B, Giovannoni G, Hawkes C, Lublin F. Multiple Sclerosis is a multifaceted disease. Multiple sclerosis and related disorders. 2014; 3(5):553-4.

Miyazaki Y, Li R, Rezk A, Misirliyan H, Moore C, Farooqi N, Solis M, Goiry LG, de Faria Junior O, Dang VD, Colman D, Dhaunchak AS, Antel J, Gommerman J, Prat A, Fillatreau S, Bar-Or A. A novel microRNA-132-sirtuin-1 axis underlies aberrant B-cell cytokine regulation in patients with relapsing-remitting multiple sclerosis [corrected]. PloS one. 2014; 9(8):e105421.

Macgowan CK, Chan KY, Laughlin S, Marrie RA, Banwell B. Cerebral arterial and venous blood flow in adolescent multiple sclerosis patients and age-matched controls using phase contrast MRI. Journal of magnetic resonance imaging : JMRI. 2014; 40(2):341-7.

Lublin FD, Reingold SC, Cohen JA, Cutter GR, Sørensen PS, Thompson AJ, Wolinsky JS, Balcer LJ, Banwell B, Barkhof F, Bebo B Jr, Calabresi PA, Clanet M, Comi G, Fox RJ, Freedman MS, Goodman AD, Inglese M, Kappos L, Kieseier BC, Lincoln JA, Lubetzki C, Miller AE, Montalban X, O'Connor PW, Petkau J, Pozzilli C, Rudick RA, Sormani MP, Stüve O, Waubant E, Polman CH. Defining the clinical course of multiple sclerosis: the 2013 revisions. Neurology. 2014; 83(3):278-86.

Banwell B, Giovannoni G, Hawkes C, Lublin F. Editors׳ welcome. Multiple sclerosis and related disorders. 2014; 3(4):417-8.

Schwartz KL, Richardson SE, Ward KN, Donaldson C, MacGregor D, Banwell B, Mahant S, Bitnun A. Delayed primary HHV-7 infection and neurologic disease. Pediatrics. 2014; 133(6):e1541-7.

Kremer L, Mealy M, Jacob A, Nakashima I, Cabre P, Bigi S, Paul F, Jarius S, Aktas O, Elsone L, Mutch K, Levy M, Takai Y, Collongues N, Banwell B, Fujihara K, de Seze J. Brainstem manifestations in neuromyelitis optica: a multicenter study of 258 patients. Multiple sclerosis (Houndmills, Basingstoke, England). 2014; 20(7):843-7.

Yiu EM, Laughlin S, Verhey LH, Banwell BL. Clinical and magnetic resonance imaging (MRI) distinctions between tumefactive demyelination and brain tumors in children. Journal of child neurology. 2014; 29(5):654-65.

Banwell B, Giovannoni G, Hawkes C, Lublin F. Editors׳ welcome. Multiple sclerosis and related disorders. 2014; 3(3):283.

Banwell B, Giovannoni G, Hawkes C, Lublin F. Editors' welcome. Multiple sclerosis and related disorders. 2014; 3(2):139-40.

Goh ES, Banwell B, Stavropoulos DJ, Shago M, Yoon G. Mosaic microdeletion of 17p11.2-p12 and duplication of 17q22-q24 in a girl with Smith-Magenis phenotype and peripheral neuropathy. American journal of medical genetics. Part A. 2014; 164A(3):748-52.

Ghassemi R, Narayanan S, Banwell B, Sled JG, Shroff M, Arnold DL. Quantitative determination of regional lesion volume and distribution in children and adults with relapsing-remitting multiple sclerosis. PloS one. 2014; 9(2):e85741.

Todorow M, DeSouza JF, Banwell BL, Till C. Interhemispheric cooperation in global-local visual processing in pediatric multiple sclerosis. Journal of clinical and experimental neuropsychology. 2014; 36(2):111-26.

Banwell BL. Multiple sclerosis in children. Handbook of clinical neurology. 2014; 122:427-41. 

Aubert-Broche B, Fonov V, Narayanan S, Arnold DL, Araujo D, Fetco D, Till C, Sled JG, Banwell B, Collins DL; Canadian Pediatric Demyelinating Disease Network. Onset of multiple sclerosis before adulthood leads to failure of age-expected brain growth. Neurology. 2014;83(23):2140-2146.

Dale RC, Brilot F, Duffy LV, Twilt M, Waldman AT, Narula S, Muscal E, Deiva K, Andersen E, Eyre MR, Eleftheriou D, Brogan PA, Kneen R, Alper G, Anlar B, Wassmer E, Heineman K, Hemingway C, Riney CJ, Kornberg A, Tardieu M, Stocco A, Banwell B, Gorman MP, Benseler SM, Lim M. Utility and safety of rituximab in pediatric autoimmune and inflammatory CNS disease. Neurology. 2014;83(2):142-150.

Waldman A, Ghezzi A, Bar-Or A, Mikaeloff Y, Tardieu M, Banwell B. Multiple sclerosis in children: an update on clinical diagnosis, therapeutic strategies, and research. Lancet Neurol. 2014;13(9):936-948.

2013

van Pelt ED, Mescheriakova JY, Makhani N, Ketelslegers IA, Neuteboom RF, Kundu S, Broer L, Janssens C, Catsman-Berrevoets CE, van Duijn CM, Banwell B, Bar-Or A, Hintzen RQ. Risk genes associated with pediatric-onset MS but not with monophasic acquired CNS demyelination. Neurology. 2013; 81(23):1996-2001.

Laughlin S, Macgowan CK, Traubici J, Chan K, Khan S, Arnold DL, Marrie RA, Banwell B. No evidence for impairment of venous hemodynamics in children or young adults with pediatric-onset multiple sclerosis. AJNR. American journal of neuroradiology. 2013; 34(12):2366-72.

Marin SE, Banwell BB, Till C. Cognitive trajectories in 4 patients with pediatric-onset multiple sclerosis: serial evaluation over a decade. Journal of child neurology. 2013; 28(12):1577-86.

Van Haren K, Tomooka BH, Kidd BA, Banwell B, Bar-Or A, Chitnis T, Tenembaum SN, Pohl D, Rostasy K, Dale RC, O'Connor KC, Hafler DA, Steinman L, Robinson WH. Serum autoantibodies to myelin peptides distinguish acute disseminated encephalomyelitis from relapsing-remitting multiple sclerosis. Multiple sclerosis (Houndmills, Basingstoke, England). 2013; 19(13):1726-33.

Yoon G, Baskin B, Tarnopolsky M, Boycott KM, Geraghty MT, Sell E, Goobie S, Meschino W, Banwell B, Ray PN. Autosomal recessive hereditary spastic paraplegia-clinical and genetic characteristics of a well-defined cohort. Neurogenetics. 2013; 14(3-4):181-8.

Ruzzo EK, Capo-Chichi JM, Ben-Zeev B, Chitayat D, Mao H, Pappas AL, Hitomi Y, Lu YF, Yao X, Hamdan FF, Pelak K, Reznik-Wolf H, Bar-Joseph I, Oz-Levi D, Lev D, Lerman-Sagie T, Leshinsky-Silver E, Anikster Y, Ben-Asher E, Olender T, Colleaux L, Décarie JC, Blaser S, Banwell B, Joshi RB, He XP, Patry L, Silver RJ, Dobrzeniecka S, Islam MS, Hasnat A, Samuels ME, Aryal DK, Rodriguiz RM, Jiang YH, Wetsel WC, McNamara JO, Rouleau GA, Silver DL, Lancet D, Pras E, Mitchell GA, Michaud JL, Goldstein DB. Deficiency of asparagine synthetase causes congenital microcephaly and a progressive form of encephalopathy. Neuron. 2013; 80(2):429-41.

Yea C, Tellier R, Chong P, Westmacott G, Marrie RA, Bar-Or A, Banwell B. Epstein-Barr virus in oral shedding of children with multiple sclerosis. Neurology. 2013; 81(16):1392-9.

Verhey LH, Signori A, Arnold DL, Bar-Or A, Sadovnick AD, Marrie RA, Banwell B, Sormani MP. Clinical and MRI activity as determinants of sample size for pediatric multiple sclerosis trials. Neurology. 2013; 81(14):1215-21.

Mayer MC, Breithaupt C, Reindl M, Schanda K, Rostásy K, Berger T, Dale RC, Brilot F, Olsson T, Jenne D, Pröbstel AK, Dornmair K, Wekerle H, Hohlfeld R, Banwell B, Bar-Or A, Meinl E. Distinction and temporal stability of conformational epitopes on myelin oligodendrocyte glycoprotein recognized by patients with different inflammatory central nervous system diseases. Journal of immunology (Baltimore, Md.: 1950). 2013; 191(7):3594-604.

Banwell B, Giovannoni G, Hawkes CH, Lublin F. Promoting regeneration and repair in Multiple Sclerosis. Multiple sclerosis and related disorders. 2013; 2(4):261-2.

Krupp LB, Tardieu M, Amato MP, Banwell B, Chitnis T, Dale RC, Ghezzi A, Hintzen R, Kornberg A, Pohl D, Rostasy K, Tenembaum S, Wassmer E. International Pediatric Multiple Sclerosis Study Group criteria for pediatric multiple sclerosis and immune-mediated central nervous system demyelinating disorders: revisions to the 2007 definitions. Multiple sclerosis (Houndmills, Basingstoke, England). 2013; 19(10):1261-7.

Bigi S, Marrie RA, Verhey L, Yeh EA, Banwell B. 2010 McDonald criteria in a pediatric cohort: is positivity at onset associated with a more aggressive multiple sclerosis course? Multiple sclerosis (Houndmills, Basingstoke, England). 2013; 19(10):1359-62.

Verhey LH, van Pelt-Gravesteijn ED, Ketelslegers IA, Neuteboom RF, Catsman-Berrevoets CE, Feldman BM, Streiner DL, Sled JG, Hintzen RQ, Banwell B. Validation of MRI predictors of multiple sclerosis diagnosis in children with acute CNS demyelination. Multiple sclerosis and related disorders. 2013; 2(3):193-9.

Banwell B, Giovannoni G, Hawkes C, Lublin F. Editorial. Multiple sclerosis and related disorders. 2013; 2(3):153.

Tenembaum SN, Banwell B, Pohl D, Krupp LB, Boyko A, Meinel M, Lehr L, Rocak S, Cantogno EV, Moraga MS, Ghezzi A. Subcutaneous interferon Beta-1a in pediatric multiple sclerosis: a retrospective study. Journal of child neurology. 2013; 28(7):849-56.

Verhey LH, Branson HM, Laughlin S, Shroff MM, Benseler SM, Feldman BM, Streiner DL, Sled JG, Banwell B. Development of a standardized MRI scoring tool for CNS demyelination in children. AJNR. American journal of neuroradiology. 2013; 34(6):1271-7.

O'Mahony J, Shroff M, Banwell B. Mimics and rare presentations of pediatric demyelination. Neuroimaging clinics of North America. 2013; 23(2):321-36.

Makhani N, Bigi S, Banwell B, Shroff M. Diagnosing neuromyelitis optica. Neuroimaging clinics of North America. 2013; 23(2):279-91.

Verhey LH, Shroff M, Banwell B. Pediatric multiple sclerosis: pathobiological, clinical, and magnetic resonance imaging features. Neuroimaging clinics of North America. 2013; 23(2):227-43.

Verhey LH, Narayanan S, Banwell B. Standardized magnetic resonance imaging acquisition and reporting in pediatric multiple sclerosis. Neuroimaging clinics of North America. 2013; 23(2):217-26.e1-7.

Freedman MS, Selchen D, Arnold DL, Prat A, Banwell B, Yeung M, Morgenthau D, Lapierre Y. Treatment optimization in MS: Canadian MS Working Group updated recommendations. The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques. 2013; 40(3):307-23.

Banwell B, Giovannoni G, Hawkes C, Lublin F. Editors' welcome and a working definition for a multiple sclerosis cure. Multiple sclerosis and related disorders. 2013; 2(2):65-7.

Chitnis T, Tardieu M, Amato MP, Banwell B, Bar-Or A, Ghezzi A, Kornberg A, Krupp LB, Pohl D, Rostasy K, Tenembaum S, Waubant E, Wassmer E. International Pediatric MS Study Group Clinical Trials Summit: meeting report. Neurology. 2013; 80(12):1161-8.

Naismith RT, Banwell BL. Can "dissemination" include the PNS in adults with acute disseminated encephalomyelitis? Neurology. 2013; 80(10):876-7.

Till C, Racine N, Araujo D, Narayanan S, Collins DL, Aubert-Broche B, Arnold DL, Banwell B. Changes in cognitive performance over a 1-year period in children and adolescents with multiple sclerosis. Neuropsychology. 2013; 27(2):210-9.

O'Mahony J, Bar-Or A, Arnold DL, Sadovnick AD, Marrie RA, Banwell B. Masquerades of acquired demyelination in children: experiences of a national demyelinating disease program. Journal of child neurology. 2013; 28(2):184-97.

Belabani C, Rajasekharan S, Poupon V, Johnson T, Bar-Or A. A condensed performance-validation strategy for multiplex detection kits used in studies of human clinical samples. Journal of immunological methods. 2013; 387(1-2):1-10.

Banwell BL. Pediatric multiple sclerosis. Handbook of clinical neurology. 2013; 112:1263-74.

Verhey LH, Banwell BL. Inflammatory, vascular, and infectious myelopathies in children. Handbook of clinical neurology. 2013; 112:999-1017.

Kimball S, Hanwell HE, Banwell B. Invited Review: Vitamin D in the Prevention and Treatment of Multiple Sclerosis. Function Food Reviews. 2013; 3(3).

Venkateswaran S, Banwell B. Clinical Trials in pediatric multiple sclerosis: overcoming the challenges. Clinical Investigation. 2013; 3(1):307-23.

2012

Bigi S, Banwell B. Pediatric multiple sclerosis. Journal of child neurology. 2012; 27(11):1378-83.

Batthish M, Banwell B, Laughlin S, Halliday W, Peschken C, Paras E, Benseler S. Refractory primary central nervous system vasculitis of childhood: successful treatment with infliximab. The Journal of rheumatology. 2012; 39(11):2227-9.

Banwell B, Giovannoni G, Hawkes C, Lublin F. Editors' welcome. Multiple sclerosis and related disorders. 2012; 1(4):153.

Sadaka Y, Verhey LH, Shroff MM, Branson HM, Arnold DL, Narayanan S, Sled JG, Bar-Or A, Sadovnick AD, McGowan M, Marrie RA, Banwell B. 2010 McDonald criteria for diagnosing pediatric multiple sclerosis. Annals of neurology. 2012; 72(2):211-23.

Till C, Ho C, Dudani A, García-Lorenzo D, Collins DL, Banwell BL. Magnetic resonance imaging predictors of executive functioning in patients with pediatric-onset multiple sclerosis. Archives of clinical neuropsychology: the official journal of the National Academy of Neuropsychologists. 2012; 27(5):495-509.

Till C, Udler E, Ghassemi R, Narayanan S, Arnold DL, Banwell BL. Factors associated with emotional and behavioral outcomes in adolescents with multiple sclerosis. Multiple sclerosis (Houndmills, Basingstoke, England). 2012; 18(8):1170-80.

Rajasekharan S, Bar-Or A. From bench to MS bedside: challenges translating biomarker discovery to clinical practice. Journal of neuroimmunology. 2012; 248(1-2):66-72.

Dale RC, Banwell B, Bar-Or A, Brilot F. Autoantibodies against aquaporin-4 and myelin oligodendrocyte glycoprotein in paediatric CNS demyelination: Recent developments and future directions. Multiple sclerosis and related disorders. 2012; 1(3):116-22.

Cohen JA, Reingold SC, Polman CH, Wolinsky JS. Disability outcome measures in multiple sclerosis clinical trials: current status and future prospects. The Lancet. Neurology. 2012; 11(5):467-76.

Dhaunchak AS, Becker C, Schulman H, De Faria O Jr, Rajasekharan S, Banwell B, Colman DR, Bar-Or A. Implication of perturbed axoglial apparatus in early pediatric multiple sclerosis. Annals of neurology. 2012; 71(5):601-13.

Fuentes A, Collins DL, Garcia-Lorenzo D, Sled JG, Narayanan S, Arnold DL, Banwell BL, Till C. Memory performance and normalized regional brain volumes in patients with pediatric-onset multiple sclerosis. Journal of the International Neuropsychological Society : JINS. 2012; 18(3):471-80.

Banwell B, Dale RC. Lymphohistiocytosis in the brain: recognition of a potentially reversible aspect of primary HLH. Neurology. 2012; 78(15):1114-5.

Banwell B, Giovannoni G, Hawkes C, Lublin F. Editors' welcome. Multiple sclerosis and related disorders. 2012; 1(2):55.

Kerbrat A, Aubert-Broche B, Fonov V, Narayanan S, Sled JG, Arnold DA, Banwell B, Collins DL.. Reduced head and brain size for age and disproportionately smaller thalami in child-onset MS. Neurology. 2012; 78(3):194-201.

Banwell B. Multiple sclerosis in children. Multiple sclerosis and related disorders. 2012; 1(1):3-5.

Banwell B, Giovannoni G, Hawkes C, Lublin F. Editor's Welcome. Multiple sclerosis and related disorders. 2012; 1(1):1-2.

Chitnis T, Tenembaum S, Banwell B, Krupp L, Pohl D, Rostasy K, Yeh EA, Bykova O, Wassmer E, Tardieu M, Kornberg A, Ghezzi A. Consensus statement: evaluation of new and existing therapeutics for pediatric multiple sclerosis. Multiple sclerosis (Houndmills, Basingstoke, England). 2012; 18(1):116-27.

Kuni BJ, Banwell BL, Till C. Cognitive and behavioral outcomes in individuals with a history of acute disseminated encephalomyelitis (ADEM). Developmental neuropsychology. 2012; 37(8):682-96.

Thomas T, Branson HM, Verhey LH, Shroff M, Stephens D, Magalhaes S, Banwell B. The demographic, clinical, and magnetic resonance imaging (MRI) features of transverse myelitis in children. Journal of child neurology. 2012; 27(1):11-21.

2011

Till C, Deotto A, Tipu V, Sled JG, Bethune A, Narayanan S, Arnold DL, Banwell BL. White matter integrity and math performance in pediatric multiple sclerosis: a diffusion tensor imaging study. Neuroreport. 2011; 22(18):1005-9.

Verhey LH, Branson HM, Shroff MM, Callen DJ, Sled JG, Narayanan S, Sadovnick AD, Bar-Or A, Arnold DL, Marrie RA, Banwell B. MRI parameters for prediction of multiple sclerosis diagnosis in children with acute CNS demyelination: a prospective national cohort study. The Lancet. Neurology. 2011; 10(12):1065-73.

Bethune A, Tipu V, Sled JG, Narayanan S, Arnold DL, Mabbott D, Rockel C, Ghassemi R, Till C, Banwell B. Diffusion tensor imaging and cognitive speed in children with multiple sclerosis. Journal of the neurological sciences. 2011; 309(1-2):68-74.

Waldman AT, Banwell BL. Acquiring new insights: incidence of acquired demyelination and MS in US children. Neurology. 2011; 77(12):1112-3

Aubert-Broche B, Fonov V, Ghassemi R, Narayanan S, Arnold DL, Banwell B, Sled JG, Collins DL. Regional brain atrophy in children with multiple sclerosis. NeuroImage. 2011; 58(2):409-15.

Pröbstel AK, Dornmair K, Bittner R, Sperl P, Jenne D, Magalhaes S, Villalobos A, Breithaupt C, Weissert R, Jacob U, Krumbholz M, Kuempfel T, Blaschek A, Stark W, Gärtner J, Pohl D, Rostasy K, Weber F, Forne I, Khademi M, Olsson T, Brilot F, Tantsis E, Dale RC, Wekerle H, Hohlfeld R, Banwell B, Bar-Or A, Meinl E, Derfuss T. Antibodies to MOG are transient in childhood acute disseminated encephalomyelitis. Neurology. 2011; 77(6):580-8.

Morin MP, Patenaude Y, Sinsky AB, Banwell B, Sébire G. Solitary tumefactive demyelinating lesions in children. Journal of child neurology. 2011; 26(8):995-9.

Makhani N, Banwell B. Noninfectious central nervous system inflammatory disorders. Seminars in pediatric neurology. 2011; 18(2):91-4.

Till C, Ghassemi R, Aubert-Broche B, Kerbrat A, Collins DL, Narayanan S, Arnold DL, Desrocher M, Sled JG, Banwell BL. MRI correlates of cognitive impairment in childhood-onset multiple sclerosis. Neuropsychology. 2011; 25(3):319-32.

Banwell B, Bar-Or A, Arnold DL, Sadovnick D, Narayanan S, McGowan M, O'Mahony J, Magalhaes S, Hanwell H, Vieth R, Tellier R, Vincent T, Disanto G, Ebers G, Wambera K, Connolly MB, Yager J, Mah JK, Booth F, Sebire G, Callen D, Meaney B, Dilenge ME, Lortie A, Pohl D, Doja A, Venketaswaran S, Levin S, Macdonald EA, Meek D, Wood E, Lowry N, Buckley D, Yim C, Awuku M, Cooper P, Grand'maison F, Baird JB, Bhan V, Marrie RA. Clinical, environmental, and genetic determinants of multiple sclerosis in children with acute demyelination: a prospective national cohort study. The Lancet. Neurology. 2011; 10(5):436-45.

Disanto G, Magalhaes S, Handel AE, Morrison KM, Sadovnick AD, Ebers GC, Banwell B, Bar-Or A. HLA-DRB1 confers increased risk of pediatric-onset MS in children with acquired demyelination. Neurology. 2011; 76(9):781-6.

Venkateswaran S, Zheng K, Sacchetti M, Gagne D, Arnold DL, Sadovnick AD, Scherer SW, Banwell B, Bar-Or A, Simon DK. Mitochondrial DNA haplogroups and mutations in children with acquired central demyelination. Neurology. 2011; 76(9):774-80.

Banwell B, Bar-Or A, Giovannoni G, Dale RC, Tardieu M. Therapies for multiple sclerosis: considerations in the pediatric patient. Nature reviews. Neurology. 2011; 7(2):109-22.

Hanwell HE, Banwell B. Assessment of evidence for a protective role of vitamin D in multiple sclerosis. Biochimica et biophysica acta. 2011; 1812(2):202-12.

Polman CH, Reingold SC, Banwell B, Clanet M, Cohen JA, Filippi M, Fujihara K, Havrdova E, Hutchinson M, Kappos L, Lublin FD, Montalban X, O'Connor P, Sandberg-Wollheim M, Thompson AJ, Waubant E, Weinshenker B, Wolinsky JS. Diagnostic criteria for multiple sclerosis: 2010 revisions to the McDonald criteria. Annals of neurology. 2011; 69(2):292-302.

Makhani N, Morris SK, Page AV, Brophy J, Lindsay LR, Banwell BL, Richardson SE. A twist on Lyme: the challenge of diagnosing European Lyme neuroborreliosis. Journal of clinical microbiology. 2011; 49(1):455-7.

Makhani N, Banwell B. Environmental Risk Factors for Pediatric Multiple Sclerosis. European neurological review. 2011; 6(3):175-80.

2010

Katz SL, Gaboury I, Keilty K, Banwell B, Vajsar J, Anderson P, Ni A, Maclusky I. Nocturnal hypoventilation: predictors and outcomes in childhood progressive neuromuscular disease. Archives of disease in childhood. 2010; 95(12):998-1003.

Verhey LH, Branson HM, Makhija M, Shroff M, Banwell B. Magnetic resonance imaging features of the spinal cord in pediatric multiple sclerosis: a preliminary study. Neuroradiology. 2010; 52(12):1153-62.

Ghezzi A, Banwell B, Boyko A, Amato MP, Anlar B, Blinkenberg M, Boon M, Filippi M, Jozwiak S, Ketelslegers I, Kornek B, Lim M, Lindstrom E, Nadj C, Neuteboom R, Rocca MA, Rostasy K, Tardieu M, Wassmer E, Catsman-Berrevoets C, Hintzen R. The management of multiple sclerosis in children: a European view. Multiple sclerosis (Houndmills, Basingstoke, England). 2010; 16(10):1258-67.

Yiu EM, Banwell B. Update on emerging therapies for multiple sclerosis. Expert review of neurotherapeutics. 2010; 10(8):1259-62.

Cheng A, Banwell B, Levin S, Seabrook JA, Freeman D, Rieder M. Oral dosing requirements for phenytoin in the first three months of life. Journal of population therapeutics and clinical pharmacology = Journal de la therapeutique des populations et de la pharamcologie clinique. 2010; 17(2):e256-61.

Malik V, Rodino-Klapac LR, Viollet L, Wall C, King W, Al-Dahhak R, Lewis S, Shilling CJ, Kota J, Serrano-Munuera C, Hayes J, Mahan JD, Campbell KJ, Banwell B, Dasouki M, Watts V, Sivakumar K, Bien-Willner R, Flanigan KM, Sahenk Z, Barohn RJ, Walker CM, Mendell JR. Gentamicin-induced readthrough of stop codons in Duchenne muscular dystrophy. Annals of neurology. 2010; 67(6):771-80.

O'Connor KC, Lopez-Amaya C, Gagne D, Lovato L, Moore-Odom NH, Kennedy J, Krupp L, Tenembaum S, Ness J, Belman A, Boyko A, Bykova O, Mah JK, Stoian CA, Waubant E, Kremenchutzky M, Ruggieri M, Bardini MR, Rensel M, Hahn J, Weinstock-Guttman B, Yeh EA, Farrell K, Freedman MS, Iivanainen M, Bhan V, Dilenge M, Hancock MA, Gano D, Fattahie R, Kopel L, Fournier AE, Moscarello M, Banwell B, Bar-Or A. Anti-myelin antibodies modulate clinical expression of childhood multiple sclerosis. Journal of neuroimmunology. 2010; 223(1-2):92-9.

Quercia N, Somers GR, Halliday W, Kantor PF, Banwell B, Yoon G. Friedreich ataxia presenting as sudden cardiac death in childhood: clinical, genetic and pathological correlation, with implications for genetic testing and counseling. Neuromuscular disorders: NMD. 2010; 20(5):340-2.

Venkateswaran S, Banwell B. Pediatric multiple sclerosis. The neurologist. 2010; 16(2):92-105.

Miller E, Widjaja E, Nilsson D, Yoon G, Banwell B, Blaser S. Magnetic resonance imaging of a unique mutation in a family with Pelizaeus-Merzbacher disease. American journal of medical genetics. Part A. 2010; 152A(3):748-52.

McMillan HJ, Campbell C, Mah JK. Duchenne muscular dystrophy: Canadian paediatric neuromuscular physicians survey. The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques. 2010; 37(2):195-205.

2009

McLaughlin KA, Chitnis T, Newcombe J, Franz B, Kennedy J, McArdel S, Kuhle J, Kappos L, Rostasy K, Pohl D, Gagne D, Ness JM, Tenembaum S, O'Connor KC, Viglietta V, Wong SJ, Tavakoli NP, de Seze J, Idrissova Z, Khoury SJ, Bar-Or A, Hafler DA, Banwell B, Wucherpfennig KW. Age-dependent B cell autoimmunity to a myelin surface antigen in pediatric multiple sclerosis. Journal of immunology (Baltimore, Md.: 1950). 2009; 183(6):4067-76.

Maegawa GH, Banwell BL, Blaser S, Sorge G, Toplak M, Ackerley C, Hawkins C, Hayes J, Clarke JT. Substrate reduction therapy in juvenile GM2 gangliosidosis. Molecular genetics and metabolism. 2009; 98(1-2):215-24.

Maegawa GH, van Giersbergen PL, Yang S, Banwell B, Morgan CP, Dingemanse J, Tifft CJ, Clarke JT. Pharmacokinetics, safety and tolerability of miglustat in the treatment of pediatric patients with GM2 gangliosidosis. Molecular genetics and metabolism. 2009; 97(4):284-91.

Makhani N, Gorman MP, Branson HM, Stazzone L, Banwell BL, Chitnis T. Cyclophosphamide therapy in pediatric multiple sclerosis. Neurology. 2009; 72(24):2076-82.

Dale RC, Brilot F, Banwell B. Pediatric central nervous system inflammatory demyelination: acute disseminated encephalomyelitis, clinically isolated syndromes, neuromyelitis optica, and multiple sclerosis. Current opinion in neurology. 2009; 22(3):233-40.

Callen DJ, Shroff MM, Branson HM, Lotze T, Li DK, Stephens D, Banwell BL. Role of MRI in the differentiation of ADEM from MS in children. Neurology. 2009; 72(11):968-73.

Baskin B, Banwell B, Khater RA, Hawkins C, Ray PN. Becker muscular dystrophy caused by an intronic mutation reducing the efficiency of the splice donor site of intron 26 of the dystrophin gene. Neuromuscular disorders : NMD. 2009; 19(3):189-92.

Yoon G, Westmacott R, Macmillan L, Quercia N, Koutsou P, Georghiou A, Christodoulou K, Banwell B. Complete deletion of the aprataxin gene: ataxia with oculomotor apraxia type 1 with severe phenotype and cognitive deficit. BMJ case reports. 2009; 2009.

Banwell B, Kennedy J, Sadovnick D, Arnold DL, Magalhaes S, Wambera K, Connolly MB, Yager J, Mah JK, Shah N, Sebire G, Meaney B, Dilenge ME, Lortie A, Whiting S, Doja A, Levin S, MacDonald EA, Meek D, Wood E, Lowry N, Buckley D, Yim C, Awuku M, Guimond C, Cooper P, Grand'Maison F, Baird JB, Bhan V, Bar-Or A. Incidence of acquired demyelination of the CNS in Canadian children. Neurology. 2009; 72(3):232-9.

2008

Miller DH, Weinshenker BG, Filippi M, Banwell BL, Cohen JA, Freedman MS, Galetta SL, Hutchinson M, Johnson RT, Kappos L, Kira J, Lublin FD, McFarland HF, Montalban X, Panitch H, Richert JR, Reingold SC, Polman CH. Differential diagnosis of suspected multiple sclerosis: a consensus approach. Multiple sclerosis (Houndmills, Basingstoke, England). 2008; 14(9):1157-74.

Banwell BL. Into the looking glass: predicting MS in children experiencing a first demyelinating event. Neurology. 2008; 71(13):962-3.

Banwell BL, Sled JG. Starting early: MRI evidence of gray matter atrophy in children with multiple sclerosis. Neurology. 2008; 70(13 Pt 2):1065-6.

Ghassemi R, Antel SB, Narayanan S, Francis SJ, Bar-Or A, Sadovnick AD, Banwell B, Arnold DL. Lesion distribution in children with clinically isolated syndromes. Annals of neurology. 2008; 63(3):401-5.

Thomas T, Banwell B. Multiple sclerosis in children. Seminars in neurology. 2008; 28(1):69-83.

Yoon G, Westmacott R, MacMillan L, Quercia N, Koutsou P, Georghiou A, Christodoulou K, Banwell B. Complete deletion of the aprataxin gene: ataxia with oculomotor apraxia type 1 with severe phenotype and cognitive deficit. Journal of neurology, neurosurgery, and psychiatry. 2008; 79(2):234-6.

Banwell B, Tenembaum S, Lennon VA, Ursell E, Kennedy J, Bar-Or A, Weinshenker BG, Lucchinetti CF, Pittock SJ. Neuromyelitis optica-IgG in childhood inflammatory demyelinating CNS disorders. Neurology. 2008; 70(5):344-52.

Banwell BL. Through the eyes of a child: research insights gained through the study of childhood multiple sclerosis. Multiple sclerosis (Houndmills, Basingstoke, England). 2008; 14(1):4-5.

Banwell B, Bar-Or A, Cheung R, Kennedy J, Krupp LB, Becker DJ, Dosch HM. Abnormal T-cell reactivities in childhood inflammatory demyelinating disease and type 1 diabetes. Annals of neurology. 2008; 63(1):98-111.

2007

Wedderburn LR, Varsani H, Li CK, Newton KR, Amato AA, Banwell B, Bove KE, Corse AM, Emslie-Smith A, Harding B, Hoogendijk J, Lundberg IE, Marie S, Minetti C, Nennesmo I, Rushing EJ, Sewry C, Charman SC, Pilkington CA, Holton JL. International consensus on a proposed score system for muscle biopsy evaluation in patients with juvenile dermatomyositis: a tool for potential use in clinical trials. Arthritis and rheumatism. 2007; 57(7):1192-201.

Banwell B, Ghezzi A, Bar-Or A, Mikaeloff Y, Tardieu M. Multiple sclerosis in children: clinical diagnosis, therapeutic strategies, and future directions. The Lancet. Neurology. 2007; 6(10):887-902.

Banwell B, Krupp L, Kennedy J, Tellier R, Tenembaum S, Ness J, Belman A, Boiko A, Bykova O, Waubant E, Mah JK, Stoian C, Kremenchutzky M, Bardini MR, Ruggieri M, Rensel M, Hahn J, Weinstock-Guttman B, Yeh EA, Farrell K, Freedman M, Iivanainen M, Sevon M, Bhan V, Dilenge ME, Stephens D, Bar-Or A. Clinical features and viral serologies in children with multiple sclerosis: a multinational observational study. The Lancet. Neurology. 2007; 6(9):773-81.

Banwell BL. The long (-itudinally extensive) and the short of it: transverse myelitis in children. Neurology. 2007; 68(18):1447-9.

Krupp LB, Banwell B, Tenembaum S. Consensus definitions proposed for pediatric multiple sclerosis and related disorders. Neurology. 2007; 68(16 Suppl 2):S7-12.

Pohl D, Waubant E, Banwell B, Chabas D, Chitnis T, Weinstock-Guttman B, Tenembaum S. Treatment of pediatric multiple sclerosis and variants. Neurology. 2007; 68(16 Suppl 2):S54-65.

Banwell B, Shroff M, Ness JM, Jeffery D, Schwid S, Weinstock-Guttman B. MRI features of pediatric multiple sclerosis. Neurology. 2007; 68(16 Suppl 2):S46-53.

Ness JM, Chabas D, Sadovnick AD, Pohl D, Banwell B, Weinstock-Guttman B. Clinical features of children and adolescents with multiple sclerosis. Neurology. 2007; 68(16 Suppl 2):S37-45.

Tenembaum S, Chitnis T, Ness J, Hahn JS. Acute disseminated encephalomyelitis. Neurology. 2007; 68(16 Suppl 2):S23-36.

Belman AL, Chitnis T, Renoux C, Waubant E. Challenges in the classification of pediatric multiple sclerosis and future directions. Neurology. 2007; 68(16 Suppl 2):S70-4.

Feasby T, Banwell B, Benstead T, Bril V, Brouwers M, Freedman M, Hahn A, Hume H, Freedman J, Pi D, Wadsworth L. Guidelines on the use of intravenous immune globulin for neurologic conditions. Transfusion medicine reviews. 2007; 21(2 Suppl 1):S57-107.

O'Connor KC, McLaughlin KA, De Jager PL, Chitnis T, Bettelli E, Xu C, Robinson WH, Cherry SV, Bar-Or A, Banwell B, Fukaura H, Fukazawa T, Tenembaum S, Wong SJ, Tavakoli NP, Idrissova Z, Viglietta V, Rostasy K, Pohl D, Dale RC, Freedman M, Steinman L, Buckle GJ, Kuchroo VK, Hafler DA, Wucherpfennig KW. Self-antigen tetramers discriminate between myelin autoantibodies to native or denatured protein. Nature medicine. 2007; 13(2):211-7.

Banwell B. Response. Pediatric Neurology. 2007; 36(4):278.

Payne ET, Rutka JT, Ho TK, Halliday WC, Banwell BL. Treatment leading to dramatic recovery in acute hemorrhagic leukoencephalitis. Journal of child neurology. 2007; 22(1):109-13.

2006

Maegawa GH, Stockley T, Tropak M, Banwell B, Blaser S, Kok F, Giugliani R, Mahuran D, Clarke JT. The natural history of juvenile or subacute GM2 gangliosidosis: 21 new cases and literature review of 134 previously reported. Pediatrics. 2006; 118(5):e1550-62.

Saengpattrachai M, Ray PN, Hawkins CE, Berzen A, Banwell BL. Grandpa and I have dystrophinopathy?: approach to asymptomatic hyperCKemia. Pediatric neurology. 2006; 35(2):145-9.

Tétreault M, Duquette A, Thiffault I, Bherer C, Jarry J, Loisel L, Banwell B, D'Anjou G, Mathieu J, Robitaille Y, Vanasse M, Brais B. A new form of congenital muscular dystrophy with joint hyperlaxity maps to 3p23-21. Brain: a journal of neurology. 2006; 129(Pt 8):2077-84.

Wilejto M, Shroff M, Buncic JR, Kennedy J, Goia C, Banwell B. The clinical features, MRI findings, and outcome of optic neuritis in children. Neurology. 2006; 67(2):258-62.

Banwell B, Reder AT, Krupp L, Tenembaum S, Eraksoy M, Alexey B, Pohl D, Freedman M, Schelensky L, Antonijevic I. Safety and tolerability of interferon beta-1b in pediatric multiple sclerosis. Neurology. 2006; 66(4):472-6.

Kennedy J, O'Connor P, Sadovnick AD, Perara M, Yee I, Banwell B. Age at onset of multiple sclerosis may be influenced by place of residence during childhood rather than ancestry. Neuroepidemiology. 2006; 26(3):162-7.

Banwell B. Genetic studies in childhood MS. MS in Focus. 2006; :16.

2005

Oddis CV, Rider LG, Reed AM, Ruperto N, Brunner HI, Koneru B, Feldman BM, Giannini EH, Miller FW. International consensus guidelines for trials of therapies in the idiopathic inflammatory myopathies. Arthritis and rheumatism. 2005; 52(9):2607-15.

Banwell B. Treatment of children and adolescents with multiple sclerosis. Expert review of neurotherapeutics. 2005; 5(3):391-401.

Al-Futaisi A, Banwell B, Ochi A, Hew J, Chu B, Oishi M, Otsubo H. Hidden focal EEG seizures during prolonged suppressions and high-amplitude bursts in early infantile epileptic encephalopathy. Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology. 2005; 116(5):1113-7.

Banwell BL, Anderson PE. The cognitive burden of multiple sclerosis in children. Neurology. 2005; 64(5):891-4.

Banwell B, Tremlett H. Coming of age: the use of immunomodulatory therapy in children with multiple sclerosis. Neurology. 2005; 64(5):778-9.

van der Knaap MS, Salomons GS, Li R, Franzoni E, Gutiérrez-Solana LG, Smit LM, Robinson R, Ferrie CD, Cree B, Reddy A, Thomas N, Banwell B, Barkhof F, Jakobs C, Johnson A, Messing A, Brenner M. Unusual variants of Alexander's disease. Annals of neurology. 2005; 57(3):327-38.

Li R, Johnson AB, Salomons G, Goldman JE, Naidu S, Quinlan R, Cree B, Ruyle SZ, Banwell B, D'Hooghe M, Siebert JR, Rolf CM, Cox H, Reddy A, Gutiérrez-Solana LG, Collins A, Weller RO, Messing A, van der Knaap MS, Brenner M. Glial fibrillary acidic protein mutations in infantile, juvenile, and adult forms of Alexander disease. Annals of neurology. 2005; 57(3):310-26.

2004

Banwell BL. Pediatric multiple sclerosis. Current neurology and neuroscience reports. 2004; 4(3):245-52.

Alotaibi S, Kennedy J, Tellier R, Stephens D, Banwell B. Epstein-Barr virus in pediatric multiple sclerosis. JAMA. 2004; 291(15):1875-9.

Hahn CD, Shroff MM, Blaser SI, Banwell BL. MRI criteria for multiple sclerosis: Evaluation in a pediatric cohort. Neurology. 2004; 62(5):806-8.

Banwell BL, Ohno K, Sieb JP, Engel AG. Novel truncating RAPSN mutations causing congenital myasthenic syndrome responsive to 3,4-diaminopyridine. Neuromuscular disorders: NMD. 2004; 14(3):202-7.

Lo B, Faiyaz-Ul-Haque M, Banwell B, Blaser S, Paterson AD, Tsui LC, Teebi AS. The locus responsible for horizontal gaze palsy/progressive scoliosis and brainstem hypoplasia is refined to a 9-cM region on chromosome 11q23. Clinical genetics. 2004; 65(2):137-42.

2003

Banwell BL, Mildner RJ, Hassall AC, Becker LE, Vajsar J, Shemie SD. Muscle weakness in critically ill children. Neurology. 2003; 61(12):1779-82.

Hahn CD, Miles BS, MacGregor DL, Blaser SI, Banwell BL, Hetherington CR. Neurocognitive outcome after acute disseminated encephalomyelitis. Pediatric neurology. 2003; 29(2):117-23.

Pan Y, Zvaritch E, Tupling AR, Rice WJ, de Leon S, Rudnicki M, McKerlie C, Banwell BL, MacLennan DH. Targeted disruption of the ATP2A1 gene encoding the sarco(endo)plasmic reticulum Ca2+ ATPase isoform 1 (SERCA1) impairs diaphragm function and is lethal in neonatal mice. The Journal of biological chemistry. 2003; 278(15):13367-75.

Lamperti C, Naini A, Hirano M, De Vivo DC, Bertini E, Servidei S, Valeriani M, Lynch D, Banwell B, Berg M, Dubrovsky T, Chiriboga C, Angelini C, Pegoraro E, DiMauro S. Cerebellar ataxia and coenzyme Q10 deficiency. Neurology. 2003; 60(7):1206-8.

2002

Minassian BA, Aiyar R, Alic S, Banwell B, Villanova M, Fardeau M, Mandell JW, Juel VC, Rafii M, Auranen M, Kalimo H. Narrowing in on the causative defect of an intriguing X-linked myopathy with excessive autophagy. Neurology. 2002; 59(4):596-601.

Banwell BL. Clinicopathologic conference: loss of milestones and failure to thrive in a 28-month-old boy. The Journal of pediatrics. 2002; 140(6):759-65.

McAdam LC, Blaser SI, Banwell BL. Pediatric tumefactive demyelination: case series and review of the literature. Pediatric neurology. 2002; 26(1):18-25.

2001

Chow GC, Clarke JT, Banwell BL. Late-onset GM2 gangliosidosis presenting as burning dysesthesias. Pediatric neurology. 2001; 25(1):59-61.

Banwell BL. Intermediate filament-related myopathies. Pediatric neurology. 2001; 24(4):257-63.

2000

Banwell BL, Engel AG. AlphaB-crystallin immunolocalization yields new insights into inclusion body myositis. Neurology. 2000; 54(5):1033-41.

1999

Banwell BL, Russel J, Fukudome T, Shen XM, Stilling G, Engel AG. Myopathy, myasthenic syndrome, and epidermolysis bullosa simplex due to plectin deficiency. Journal of neuropathology and experimental neurology. 1999; 58(8):832-46.

Banwell BL, Becker LE, Jay V, Taylor GP, Vajsar J. Cardiac manifestations of congenital fiber-type disproportion myopathy. Journal of child neurology. 1999; 14(2):83-7.

1994

Banwell BL, Singh NC, Ramsay DA. Prolonged survival in neonatal nemaline rod myopathy. Pediatric neurology. 1994; 10(4):335-7.

Leadership and Memberships

CHOP Clinical Trials Research Affinity Group, Advisory committee member