Brenda L. Banwell, MD

Brenda L. Banwell, MD

Brenda L. Banwell, MD, is Chief of the Division of Neurology at Children's Hospital of Philadelphia and holder of the Grace R. Loeb Endowed Chair in Neurosciences.

Areas of Expertise: Pediatric multiple sclerosis, Inflammatory brain disorders, Acquired demyelinating diseases
Locations: Main Campus
Appointments and Referrals: 1-800-TRY-CHOP (1-800-879-2467)

Background

Brenda L. Banwell, MD, is chief of the Division of Neurology at The Children's Hospital of Philadelphia.

Dr. Banwell graduated with a degree in medicine from The University of Western Ontario in 1991. She pursued a residency in pediatrics at The Hospital of Western Ontario, University of Western Ontario, from 1991-1994 and a pediatric neurology residency at The Hospital for Sick Children, University of Toronto from 1994-1997. Dr. Banwell then spent two years completing a neuromuscular disease fellowship at the Mayo Clinic, Rochester, Minnesota. In 1999, Dr. Banwell was appointed as an assistant professor of paediatrics (neurology) at the Hospital for Sick Children and University of Toronto. She was promoted to associate professor in 2006 and full professor in 2012. As of July 1, 2012, Dr. Banwell has taken on the role of chief of Neurology at The Children’s Hospital of Philadelphia.

Dr. Banwell’s clinical and research interests are in pediatric multiple sclerosis and other inflammatory brain disorders. She remains the lead investigator of the Canadian Pediatric Demyelinating Disease Program, which has now partnered with the pediatric demyelinating disease program in Philadelphia.

Here at CHOP, Dr. Banwell is the director of the Pediatric Multiple Sclerosis Clinic, a multidisciplinary clinic dedicated to children with multiple sclerosis and other acquired demyelinating diseases. Her clinical studies focus on the cognitive and neuroimaging features of pediatric multiple sclerosis, while the basic science work focuses on T and B-cell autoimmunity studies, MRI imaging, and studies of viral triggers.

Dr. Banwell is the principal investigator of a 23-site, eight-year study of acute demyelination in children from every pediatric health care facility in Canada and now CHOP (funded by the Canadian Multiple Sclerosis Research Foundation and CHOP). She holds CIHR Investigator Grants, operating grants from the Canadian Multiple Sclerosis Society, and has been successfully funded for over 12 years.

Dr. Banwell has more than 100 manuscripts published in high impact journals (including JAMA, Lancet Neurology and Nature Medicine), as well as 11 book chapters. She has over 100 invited lectureships or visiting Professorships in Canada, the United States and Europe.

Education and Training

Medical School

MD - University of Western Ontario, London, Ontario

Internship

Pediatrics - University of Western Ontario-Children's Hospital of Western Ontario, London, Ontario

Residency

Pediatrics - University of Western Ontario-Children's Hospital of Western Ontario, London, Ontario
Pediatric Neurology - University of Toronto - The Hospital for Sick Children, Toronto, Ontario (Chief Resident)

Fellowship

Neuromuscular Research - Mayo Clinic, Rochester, MN

Board Certification

Neurology
Pediatrics

Titles and Academic Titles

Chief, Division of Neurology

Professor of Neurology, Perelman School of Medicine at the University of Pennsylvania

Departments and Services

Research Interests

Pediatric multiple sclerosis and other inflammatory brain disorders
Acute demyelination in children
Cognitive and neuroimaging features of pediatric multiple sclerosis
T and B-cell autoimmunity studies, MRI imaging, and studies of viral triggers in children with multiple sclerosis

Publications

Papers

2017

Datta R, Sethi V, Ly S, Waldman AT, Narual S, Dewey BE, Sati P, Reich D, Banwell F. 7T MRI Visualization of Cortical Lesions in Adolescents and Young Adults with Pediatric-Onset Multiple Sclerosis. J Neuroimaging. 2017 Aug 10. doi: 10.1111/jon.12465. [Epub ahead of print]

2014

Aubert-Broche B, Fonov V, Narayanan S, Arnold DL, Araujo D, Fetco D, Till C, Sled JG, Banwell B, Collins DL; Canadian Pediatric Demyelinating Disease Network. Onset of multiple sclerosis before adulthood leads to failure of age-expected brain growth. Neurology. 2014;83(23):2140-2146.

Dale RC, Brilot F, Duffy LV, Twilt M, Waldman AT, Narula S, Muscal E, Deiva K, Andersen E, Eyre MR, Eleftheriou D, Brogan PA, Kneen R, Alper G, Anlar B, Wassmer E, Heineman K, Hemingway C, Riney CJ, Kornberg A, Tardieu M, Stocco A, Banwell B, Gorman MP, Benseler SM, Lim M. Utility and safety of rituximab in pediatric autoimmune and inflammatory CNS disease. Neurology. 2014;83(2):142-150.

Waldman A, Ghezzi A, Bar-Or A, Mikaeloff Y, Tardieu M, Banwell B. Multiple sclerosis in children: an update on clinical diagnosis, therapeutic strategies, and research. Lancet Neurol. 2014;13(9):936-948.