Brenda L. Banwell, MD

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Brenda L. Banwell, MD, is Chief of the Division of Neurology and Co-Director of the Neuroscience Center at Children's Hospital of Philadelphia and holder of the Grace R. Loeb Endowed Chair in Neurosciences.

Areas of Expertise: Pediatric multiple sclerosis, Inflammatory brain disorders, Acquired demyelinating diseases
Locations: Main Hospital; Buerger Center for Advanced Pediatric Care

Background

Brenda L. Banwell, MD, is Chief of the Division of Neurology and Co-Director of the Neuroscience Center at the Children's Hospital of Philadelphia (CHOP). She specializes in pediatric multiple sclerosis and other neuroimmune disorders.

“I have always been fascinated by the brain and committed to caring for children and teenagers living with neurological disorders,” she says.

Dr. Banwell cares deeply about the experience of children living with multiple sclerosis and related disorders. She focuses clinical time on speaking to children and teenagers and ensuring their views are heard. Dr. Banwell has broadened her reach by authoring social media posts, brochures, and online materials for children and families, and by participating in podcasts discussing pediatric care for children with multiple sclerosis and other neuroimmune disorders.

Research holds great promise for the treatment of multiple sclerosis, with 16 different therapies available and many more expected, Dr. Banwell says.

“Multiple sclerosis is rapidly becoming a very treatable disease, although patients require expert care,” she says.

Dr. Banwell is the co-director of the Pediatric Multiple Sclerosis and Neuroinflammatory Disorders Clinic at CHOP, a multidiscipline clinical and research program dedicated to children and adults with multiple sclerosis and other acquired demyelinating diseases.

“The program offers world-class care and leads in studies to advance our understanding of these disorders,” she says.

Dr. Banwell’s clinical studies involve using an MRI to assess the impact of these diseases on the brain by measuring brain volume and brain tissue features. She is also involved in studies of the immune system in children and teenagers with multiple sclerosis and neuroimmune disease.

Dr. Banwell is the principal investigator of the Canadian Pediatric Demyelinating Disease Program, a 23-site, 15-year study of acute demyelination in children from every pediatric health care facility in Canada as well as from CHOP. She holds a new National Multiple Sclerosis Society Grant to study the impact of marijuana on youth with multiple sclerosis. She and Dr. Bar-Or lead the Multiple Sclerosis Clinical Fellowship, funded as an institutional grant by the National Multiple Sclerosis Society. Dr. Banwell is also a co-principal investigator of the NIH-funded PENN NeuroNEXT award.

Along with her work at CHOP, Dr. Banwell is a Professor of Neurology and Pediatrics at the Perelman School of Medicine at the University of Pennsylvania. She has more than 250 manuscripts published in high impact journals (including JAMA, Lancet Neurology and Nature Medicine), as well as over 25 book chapters. She has over 200 invited lectureships or visiting professorships nationally and internationally.

Dr. Banwell advocates for pediatric multiple sclerosis needs and research as the Chair of the International Pediatric Multiple Sclerosis Study Group, and as Director of the International Medical and Scientific Advisory Board of the Multiple Sclerosis International Federation.

Education and Training

Medical School

MD - University of Western Ontario, London, Ontario

Internship

Pediatrics - University of Western Ontario-Children's Hospital of Western Ontario, London, Ontario

Residency

Pediatrics - University of Western Ontario-Children's Hospital of Western Ontario, London, Ontario
Pediatric Neurology - University of Toronto - The Hospital for Sick Children, Toronto, Ontario (Chief Resident)

Fellowship

Neuromuscular Research - Mayo Clinic, Rochester, MN

Board Certification

Neurology – American Board of Psychiatry and Neurology
Pediatrics – American Board of Pediatrics

Titles and Academic Titles

Chief, Division of Neurology

Professor of Neurology, Perelman School of Medicine at the University of Pennsylvania

Professor of Pediatrics, Perelman School of Medicine at the University of Pennsylvania

Conditions Treated

Departments and Services

Research Interests

Pediatric multiple sclerosis and other inflammatory brain disorders

Acute demyelination in children

Cognitive and neuroimaging features of pediatric multiple sclerosis

T and B-cell autoimmunity studies, MRI imaging, and studies of viral triggers in children with multiple sclerosis

Publications

Papers

2020

Dong A., Ghiaccio V., Motta I., Guo S., Peralta R., Freier S.M., Watt A., Damle S., Ikawa Y., Jarocha D., Chappell M., Stephanou C., Delbini P., Chen C., Christou S., Kleanthous M., Smith-Whitley K., Manwani D., Casu C., Abdulmalik O., Cappellini M.D., Rivella S., and Breda L: 2'-O- methoxyethyl Splice-Switching Oligos Correct Splicing From IVS2-745 Beta-Thalassemia Patients Cells Restoring HbA Production and Chain Rebalance. Haematologica 2020. PMID: 32439726

2019

Ghiaccio V., Chappell M. E., Rivella S., Breda L: Gene Therapy for Beta- Hemoglobinopathies: Milestones, New Therapies and Challenges. Molecular Diagnosis & Therapy 2019. PMID: 30701409

Guerra A., Oikomidou Rea Paraskevi., Sinha Sa, Zhang J., Lo Presti V., Hamilton C.R., Breda L., Casu C., La P., Martins A. C., Sendamarai A. K., Fleming M., Rivella S: Lack of Gdf11 does not improve anemia or prevent the activity of RAP-536 in a mouse model of beta-thalassemia. Blood 2019. PMID: 31151988

Neuteboom RF, Banwell B: In memoriam: Prof. Rogier Q. Hintzen, MD, PhD (1963-2019). Mult Scler 25(9): 1209-1210, Aug 2019.

Magalhaes S, Banwell B, Bar-Or A, Fortier I, Hanwell HE, Lim M, Matt GE, Neuteboom RF, O'Riordan DL, Schneider PK, Pugliatti M, Shatenstein B, Tansey CM, Wassmer E, Wolfson C: A framework for measurement and harmonization of pediatric multiple sclerosis etiologic research studies: The Pediatric MS Tool-Kit. Multiple Sclerosis 25(8): 1170-1177, Jul 2019.

Datta R, Sollee JR, Lavery AM, Ficerai-Garland G, Karoscik K, Liu G, Banwell BL, Waldman AT.: Effects of Optic Neuritis, T2 Lesions, and Microstructural Diffusion Integrity in the Visual Pathway on Cortical Thickness in Pediatric-Onset Multiple Sclerosis. J Neuroimaging Jul 2019 Notes: Epub ahead of print.

Marrie RA, O'Mahony J, Maxwell CJ, Ling V, Yeh EA, Arnold DL, Bar-Or A, Banwell B; Canadian Pediatric Demyelinating Disease Network.: High rates of health care utilization in pediatric multiple sclerosis: A Canadian population-based study. PLoS One 14(6): e0218215, Jun 2019.

Filippi M, Preziosa P, Banwell BL, Barkhof F, Ciccarelli O, De Stefano N, Geurts JJG, Paul F, Reich DS, Toosy AT, Traboulsee A, Wattjes MP, Yousry TA, Gass A, Lubetzki C, Weinshenker BG, Rocca MA.: Assessment of lesions on magnetic resonance imaging in multiple sclerosis: practical guidelines. Brain Jun 2019 Notes: Epub ahead of print.

Banwell B: Are children with multiple sclerosis really "old" adults. Mult Scler 25(7): 888-890, Jun 2019.

Maranzano J, Till C, Assemlal HE, Fonov V, Brown R, Araujo D, O'Mahony J, Yeh EA, Bar-Or A, Marrie RA, Collins L, Banwell B, Arnold DL, Narayanan S.  Detection and clinical correlation of leukocortical lesions in pediatric-onset multiple sclerosis on multi-contrast MRI. Mult Scler. 2019 Jun;25(7):980-986. doi: 10.1177/1352458518779952. Epub 2018 Jun 1. PubMed PMID: 29852831.

Waubant E, Banwell B, Wassmer E, Sormani MP, Amato MP, Hintzen R, Krupp L, Rostásy K, Tenembaum S, Chitnis T.  Clinical trials of disease-modifying agents in pediatric MS: Opportunities, challenges, and recommendations from the IPMSSG. Neurology. 2019 May 1;. doi: 10.1212/WNL.0000000000007572. [Epub ahead of print] PubMed PMID: 31043474.

Banwell B.  Are children with multiple sclerosis really "old" adults. Mult Scler. 2019 Apr 4;:1352458519841505. doi: 10.1177/1352458519841505. [Epub ahead of print] PubMed PMID: 30945591.

Lavery AM, Collins BN, Waldman AT, Hart CN, Bar-Or A, Marrie RA, Arnold D, O'Mahony J, Banwell B.  The contribution of secondhand tobacco smoke exposure to pediatric multiple sclerosis risk. Mult Scler. 2019 Apr;25(4):515-522. doi: 10.1177/1352458518757089. Epub 2018 Feb 2. PubMed PMID: 29393768.

Barlow-Krelina E, Turner GR, Akbar N, Banwell B, Lysenko M, Yeh EA, Narayanan S, Collins DL, Aubert-Broche B, Till C.  Enhanced Recruitment During Executive Control Processing in Cognitively Preserved Patients With Pediatric-Onset MS. J Int Neuropsychol Soc. 2019 Apr;25(4):432-442. doi: 10.1017/S135561771800125X. Epub 2019 Feb 28. PubMed PMID: 30813973.

Mexhitaj I, Nyirenda MH, Li R, O'Mahony J, Rezk A, Rozenberg A, Moore CS, Johnson T, Sadovnick D, Collins DL, Arnold DL, Gran B, Yeh EA, Marrie RA, Banwell B, Bar-Or A.  Abnormal effector and regulatory T cell subsets in paediatric-onset multiple sclerosis. Brain. 2019 Mar 1;142(3):617-632. doi: 10.1093/brain/awz017. PubMed PMID: 30759186; PubMed Central PMCID: PMC6391601.

Fadda G, Brown RA, Magliozzi R, Aubert-Broche B, O'Mahony J, Shinohara RT, Banwell B, Marrie RA, Yeh EA, Collins DL, Arnold DL, Bar-Or A.  A surface-in gradient of thalamic damage evolves in pediatric multiple sclerosis. Ann Neurol. 2019 Mar;85(3):340-351. doi: 10.1002/ana.25429. Epub 2019 Feb 20. PubMed PMID: 30719730. 

2018

Tantsis EM, Prelog K, Alper G, Benson L, Gorman M, Lim M, Mohammad SS, Ramanathan S, Brilot F, Dale RC.  Magnetic resonance imaging in enterovirus-71, myelin oligodendrocyte glycoprotein antibody, aquaporin-4 antibody, and multiple sclerosis-associated myelitis in children. Dev Med Child Neurol. 2018 Dec 10;. doi: 10.1111/dmcn.14114. [Epub ahead of print] PubMed PMID: 30537075. 

Longoni G, Brown RA, Aubert-Broche B, Grover SA, Branson HM, Fetco D, Bar-Or A, Marrie RA, Motl RW, Collins DL, Narayanan S, Arnold DL, Banwell B, Yeh EA.  Physical activity and dentate gyrus volume in pediatric acquired demyelinating syndromes. Neurol Neuroimmunol Neuroinflamm. 2018 Nov;5(6):e499. doi: 10.1212/NXI.0000000000000499. eCollection 2018 Nov. PubMed PMID: 30211252; PubMed Central PMCID: PMC6131051.

Marrie RA, O'Mahony J, Maxwell C, Ling V, Yeh EA, Arnold DL, Bar-Or A, Banwell B.  Incidence and prevalence of MS in children: A population-based study in Ontario, Canada. Neurology. 2018 Oct 23;91(17):e1579-e1590. doi: 10.1212/WNL.0000000000006395. Epub 2018 Sep 26. PubMed PMID: 30258022. 

Gofshteyn JS, Shaw PA, Teachey DT, Grupp SA, Maude S, Banwell B, Chen F, Lacey SF, Melenhorst JJ, Edmonson MJ, Panzer J, Barrett DM, McGuire JL.  Neurotoxicity after CTL019 in a pediatric and young adult cohort. Ann Neurol. 2018 Oct;84(4):537-546. doi: 10.1002/ana.25315. Epub 2018 Sep 26. PubMed PMID: 30178481; PubMed Central PMCID: PMC6444896.

Chitnis T, Arnold DL, Banwell B, Brück W, Ghezzi A, Giovannoni G, Greenberg B, Krupp L, Rostásy K, Tardieu M, Waubant E, Wolinsky JS, Bar-Or A, Stites T, Chen Y, Putzki N, Merschhemke M, Gärtner J.  Trial of Fingolimod versus Interferon Beta-1a in Pediatric Multiple Sclerosis. N Engl J Med. 2018 Sep 13;379(11):1017-1027. doi: 10.1056/NEJMoa1800149. PubMed PMID: 30207920. 

O'Mahony J, Marrie RA, Laporte A, Bar-Or A, Yeh EA, Brown A, Dilenge ME, Banwell B.  Pediatric-onset multiple sclerosis is associated with reduced parental health-related quality of life and family functioning. Mult Scler. 2018 Aug 30;:1352458518796676. doi: 10.1177/1352458518796676. [Epub ahead of print] PubMed PMID: 30160208. 

McNicholas N, Hutchinson M, McGuigan C, Chataway J. 2017 McDonald diagnostic criteria: A review of the evidence. Multiple sclerosis and related disorders. 2018; 24:48-54.

Wells E, Hacohen Y, Waldman A, Tillema JM, Soldatos A, Ances B, Benseler S, Bielekova B, Dale RC, Dalmau J, Gaillard W, Gorman M, Greenberg B, Hyslop A, Pardo CA, Tasker RC, Yeh EA, Bar-Or A, Pittock S, Vanderver A, Banwell B. Neuroimmune disorders of the central nervous system in children in the molecular era. Nature reviews. Neurology. 2018;

Green R, Adler A, Banwell BL, Fabri TL, Yeh EA, Collins DL, Sled JG, Narayanan S, Till C. Involvement of the Amygdala in Memory and Psychosocial Functioning in Pediatric-Onset Multiple Sclerosis. Developmental neuropsychology. 2018; :1-11.

Parmar K, Banwell BL, Akbar N, Bigi S. Imaging Pediatric Multiple Sclerosis-Challenges and Recent Advances. Neuropediatrics. 2018; 49(3):165-172.

Magalhaes S, Banwell B, Bar-Or A, Fortier I, Hanwell HE, Lim M, Matt GE, Neuteboom RF, O'Riordan DL, Schneider PK, Pugliatti M, Shatenstein B, Tansey CM, Wassmer E, Wolfson C. A framework for measurement and harmonization of pediatric multiple sclerosis etiologic research studies: The Pediatric MS Tool-Kit. Multiple sclerosis (Houndmills, Basingstoke, England). 2018; :1352458518783345.

Maranzano J, Till C, Assemlal HE, Fonov V, Brown R, Araujo D, O'Mahony J, Yeh EA, Bar-Or A, Marrie RA, Collins L, Banwell B, Arnold DL, Narayanan S. Detection and clinical correlation of leukocortical lesions in pediatric-onset multiple sclerosis on multi-contrast MRI. Multiple sclerosis (Houndmills, Basingstoke, England). 2018; :1352458518779952.

Yeh EA, Grover SA, Powell VE, Alper G, Banwell BL, Edwards K, Gorman M, Graves J, Lotze TE, Mah JK, Mednick L, Ness J, Obadia M, Slater R, Waldman A, Waubant E, Schwartz CE. Correction to: Impact of an electronic monitoring device and behavioural feedback on adherence to multiple sclerosis therapies in youth: results of a randomized trial. Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation. 2018; 27(4):1117.

Brenton JN, Schreiner T, Karoscik K, Richter M, Ferrante S, Waldman A, Banwell B. Attitudes, perceptions, and use of marijuana in youth with multiple sclerosis. Journal of neurology. 2018; 265(2):417-423.

Schwartz CE, Grover SA, Powell VE, Noguera A, Mah JK, Mar S, Mednick L, Banwell BL, Alper G, Rensel M, Gorman M, Waldman A, Schreiner T, Waubant E, Yeh EA. Risk factors for non-adherence to disease-modifying therapy in pediatric multiple sclerosis. Multiple sclerosis (Houndmills, Basingstoke, England). 2018; 24(2):175-185.

Lavery AM, Collins BN, Waldman AT, Hart CN, Bar-Or A, Marrie RA, Arnold D, O'Mahony J, Banwell B. The contribution of secondhand tobacco smoke exposure to pediatric multiple sclerosis risk. Multiple sclerosis (Houndmills, Basingstoke, England). 2018; :1352458518757089.

2017

Baskin B, Kalia LV, Banwell BL, Ray PN, Yoon G. Complex genomic rearrangement in SPG11 due to a DNA replication-based mechanism. Movement disorders : official journal of the Movement Disorder Society. 2017; 32(12):1792-1794.

Banwell B, Marrie RA. Increased relapse rate during pregnancy and postpartum in neuromyelitis optica. Neurology. 2017; 89(22):2220-2221.

Scolding NJ, Pasquini M, Reingold SC, Cohen JA. Cell-based therapeutic strategies for multiple sclerosis. Brain : a journal of neurology. 2017; 140(11):2776-2796.

Abath Neto O, Moreno CAM, Malfatti E, Donkervoort S, Böhm J, Guimarães JB, Foley AR, Mohassel P, Dastgir J, Bharucha-Goebel DX, Monges S, Lubieniecki F, Collins J, Medne L, Santi M, Yum S, Banwell B, Salort-Campana E, Rendu J, Fauré J, Yis U, Eymard B, Cheraud C, Schneider R, Thompson J, Lornage X, Mesrob L, Lechner D, Boland A, Deleuze JF, Reed UC, Oliveira ASB, Biancalana V, Romero NB, Bönnemann CG, Laporte J, Zanoteli E. Common and variable clinical, histological, and imaging findings of recessive RYR1-related centronuclear myopathy patients. Neuromuscular disorders : NMD. 2017; 27(11):975-985.

Gordon-Lipkin E, Banwell B. An update on multiple sclerosis in children: diagnosis, therapies, and prospects for the future. Expert review of clinical immunology. 2017; 13(10):975-989.

Ortiz-Gonzalez X, Goldberg EM, Banwell B. Obituary: Jessica Anne Panzer, MD, PhD. Pediatric neurology. 2017; 75:4-5.

Till C, Kuni B, De Somma E, Yeh EA, Banwell B. A feasibility study of working memory training for individuals with paediatric-onset multiple sclerosis. Neuropsychological rehabilitation. 2017; :1-16.

Akbar N, Signori A, Amato MP, Sormani MP, Portaccio E, Niccolai C, Goretti B, Till C, Banwell B. Maturational Trajectory of Processing Speed Performance in Pediatric Multiple Sclerosis. Developmental neuropsychology. 2017; 42(5):299-308.

Datta R, Sethi V, Ly S, Waldman AT, Narula S, Dewey BE, Sati P, Reich D, Banwell B. 7T MRI Visualization of Cortical Lesions in Adolescents and Young Adults with Pediatric-Onset Multiple Sclerosis. Journal of neuroimaging: official journal of the American Society of Neuroimaging. 2017; 27(5):447-452. NIHMSID: NIHMS894813

Yeh EA, Grover SA, Powell VE, Alper G, Banwell BL, Edwards K, Gorman M, Graves J, Lotze TE, Mah JK, Mednick L, Ness J, Obadia M, Slater R, Waldman A, Waubant E, Schwartz CE. Impact of an electronic monitoring device and behavioral feedback on adherence to multiple sclerosis therapies in youth: results of a randomized trial. Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation. 2017; 26(9):2333-2349.

Corwin DJ, Topjian A, Banwell BL, Osterhoudt K. Adverse events associated with a large dose of intravenous lipid emulsion for suspected local anesthetic toxicity. Clinical toxicology (Philadelphia, Pa.). 2017; 55(6):603-607.

Waldman AT, Liu GT, Lavery AM, Liu G, Gaetz W, Aleman TS, Banwell BL. Optical coherence tomography and visual evoked potentials in pediatric MS. Neurology(R) neuroimmunology & neuroinflammation. 2017; 4(4):e356.

Yeshokumar AK, Narula S, Banwell B. Pediatric multiple sclerosis. Current opinion in neurology. 2017; 30(3):216-221.

Aubert-Broche B, Weier K, Longoni G, Fonov VS, Bar-Or A, Marrie RA, Yeh EA, Narayanan S, Arnold DL, Verhey LH, Banwell B, Collins DL. Monophasic demyelination reduces brain growth in children. Neurology. 2017; 88(18):1744-1750.

Longoni G, Brown RA, Momayyez Siahkal P, Elliott C, Narayanan S, Bar-Or A, Marrie RA, Yeh EA, Filippi M, Banwell B, Arnold DL. White matter changes in paediatric multiple sclerosis and monophasic demyelinating disorders. Brain: a journal of neurology. 2017; 140(5):1300-1315.

Bigi S, Marrie RA, Till C, Yeh EA, Akbar N, Feinstein A, Banwell BL. The computer-based Symbol Digit Modalities Test: establishing age-expected performance in healthy controls and evaluation of pediatric MS patients. Neurological sciences: official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology. 2017; 38(4):635-642.

Lin JJ, Banwell BL, Berg RA, Dlugos DJ, Ichord RN, Kilbaugh TJ, Kirsch RE, Kirschen MP, Licht DJ, Massey SL, Naim MY, Rintoul NE, Topjian AA, Abend NS. Electrographic Seizures in Children and Neonates Undergoing Extracorporeal Membrane Oxygenation. Pediatric critical care medicine: a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies. 2017; 18(3):249-257. NIHMSID: NIHMS829174

Banwell B. Paediatric neurology in 2016: a year in review. The Lancet. Neurology. 2017; 16(1):14-15.

2016

Breda Laura, Motta Irene, Lourenco Silvia, Gemmo Chiara, Deng Wulan, Rupon Jeremy W, Abdulmalik Osheiza Y, Manwani Deepa, Blobel Gerd A, Rivella Stefano: Forced chromatin looping raises fetal hemoglobin in adult sickle cells to higher levels than pharmacologic inducers. Blood 128(8): 1139-43, Aug 2016. PMID: 27405777

Cosenza Lucia Carmela, Breda Laura, Breveglieri Giulia, Zuccato Cristina, Finotti Alessia, Lampronti Ilaria, Borgatti Monica, Chiavilli Francesco, Gamberini Maria Rita, Satta Stefania, Manunza Laura, De Martis Franca Rosa, Moi Paolo, Rivella Stefano, Gambari Roberto, Bianchi Nicoletta: A validated cellular biobank for β- thalassemia. Journal of translational medicine 14(1): 255, Sep 2016. PMID: 27590532

Siegler JE, Banwell B, Ichord RN. Teaching NeuroImages: Intracranial vertebral dissection in a 15-year-old boy with sickle cell disease. Neurology. 2016; 87(24):e290-e291.

Grover SA, Sawicki CP, Kinnett-Hopkins D, Finlayson M, Schneiderman JE, Banwell B, Till C, Motl RW, Yeh EA. Physical Activity and Its Correlates in Youth with Multiple Sclerosis. The Journal of pediatrics. 2016; 179:197-203.e2.

Waldman AT, Chahin S, Lavery AM, Liu G, Banwell BL, Liu GT, Balcer LJ. Binocular low-contrast letter acuity and the symbol digit modalities test improve the ability of the Multiple Sclerosis Functional Composite to predict disease in pediatric multiple sclerosis. Multiple sclerosis and related disorders. 2016; 10:73-78.

Till C, Noguera A, Verhey LH, O'Mahony J, Yeh EA, Mah JK, Sinopoli KJ, Brooks BL, Aubert-Broche B, Collins DL, Narayanan S, Arnold DL, Banwell BL. Cognitive and Behavioral Functioning in Childhood Acquired Demyelinating Syndromes. Journal of the International Neuropsychological Society : JINS. 2016; 22(10):1050-1060.

Banwell B. Clinical trials for pediatric MS should be prioritized to test only one or two of the most promising agents - YES. Multiple sclerosis (Houndmills, Basingstoke, England). 2016; 22(13):1649-1651.

Al-Maawali A, Yoon G, Feigenbaum AS, Halliday WC, Clarke JT, Branson HM, Banwell BL, Chitayat D, Blaser SI. Validation of the finding of hypertrophy of the clava in infantile neuroaxonal dystrophy/PLA2G6 by biometric analysis. Neuroradiology. 2016; 58(10):1035-1042.

Lavery AM, Banwell BL, Liu G, Waldman AT. Hospital admission rates for pediatric multiple sclerosis in the United States using the Pediatric Health Information System (PHIS). Multiple sclerosis and related disorders. 2016; 9:5-10.

Weier K, Fonov V, Aubert-Broche B, Arnold DL, Banwell B, Collins DL. Impaired growth of the cerebellum in pediatric-onset acquired CNS demyelinating disease. Multiple sclerosis (Houndmills, Basingstoke, England). 2016; 22(10):1266-78.

Banwell B, Arnold DL, Tillema JM, Rocca MA, Filippi M, Weinstock-Guttman B, Zivadinov R, Sormani MP. MRI in the evaluation of pediatric multiple sclerosis. Neurology. 2016; 87(9 Suppl 2):S88-96.

Tardieu M, Banwell B, Wolinsky JS, Pohl D, Krupp LB. Consensus definitions for pediatric MS and other demyelinating disorders in childhood. Neurology. 2016; 87(9 Suppl 2):S8-S11.

Hintzen RQ, Dale RC, Neuteboom RF, Mar S, Banwell B. Pediatric acquired CNS demyelinating syndromes: Features associated with multiple sclerosis. Neurology. 2016; 87(9 Suppl 2):S67-73.

Wassmer E, Chitnis T, Pohl D, Amato MP, Banwell B, Ghezzi A, Hintzen RQ, Krupp LB, Makhani N, Rostásy K, Tardieu M, Tenembaum S, Waldman A, Waubant E, Kornberg AJ. International Pediatric MS Study Group Global Members Symposium report. Neurology. 2016; 87(9 Suppl 2):S110-6.

Schiffmann R, Banwell B. Brain MRI and motor function in leukodystrophies. Schiffmann R, Banwell B. Neurology. 2016; 87(8):748-9.

Banwell B. Pediatric multiple sclerosis: The 2015 Sydney Carter Award Lecture. Neurology. 2016; 87(8):822-6.

Narula S, Banwell B. Pediatric Demyelination. Continuum (Minneapolis, Minn.). 2016; 22(3):897-915.

Banwell B, Giovannoni G, Hawkes C, Lublin F. Editors' Welcome. Multiple sclerosis and related disorders. 2016; 7:A1-2.Williams RP, Banwell B, Berg RA, Dlugos DJ, Donnelly M, Ichord R, Kessler SK, Lavelle J, Massey SL, Hewlett J, Parker A, Topjian AA, Abend NS. Impact of an ICU EEG monitoring pathway on timeliness of therapeutic intervention and electrographic seizure termination. Epilepsia. 2016; 57(5):786-95.

Akbar N, Till C, Sled JG, Binns MA, Doesburg SM, Aubert-Broche B, Collins DL, Araujo D, Narayanan S, Arnold DL, Lysenko M, Banwell B. Altered resting-state functional connectivity in cognitively preserved pediatric-onset MS patients and relationship to structural damage and cognitive performance. Multiple sclerosis (Houndmills, Basingstoke, England). 2016; 22(6):792-800.

Krupp LB, Pohl D, Ghezzi A, Boyko A, Tenembaum S, Chen L, Aycardi E, Banwell B. Subcutaneous interferon β-1a in pediatric patients with multiple sclerosis: Regional differences in clinical features, disease management, and treatment outcomes in an international retrospective study. Journal of the neurological sciences. 2016; 363:33-8.

Marrie RA, Miller A, Sormani MP, Thompson A, Waubant E, Trojano M, O'Connor P, Reingold S, Cohen JA. The challenge of comorbidity in clinical trials for multiple sclerosis. Neurology. 2016; 86(15):1437-45.

Marrie RA, Miller A, Sormani MP, Thompson A, Waubant E, Trojano M, O'Connor P, Fiest K, Reider N, Reingold S, Cohen JA. Recommendations for observational studies of comorbidity in multiple sclerosis. Neurology. 2016; 86(15):1446-53.

Gmuca S, Boos MD, Treece A, Narula S, Billinghurst L, Bhatti T, Laje P, Perman MJ, Vossough A, Harding B, Burnham J, Banwell B. Degos disease mimicking primary vasculitis of the CNS. Neurology(R) neuroimmunology & neuroinflammation. 2016; 3(2):e206.

Weier K, Till C, Fonov V, Yeh EA, Arnold DL, Banwell B, Collins DL. Contribution of the cerebellum to cognitive performance in children and adolescents with multiple sclerosis. Multiple sclerosis (Houndmills, Basingstoke, England). 2016; 22(5):599-607.

Rocca MA, Sonkin M, Copetti M, Pagani E, Arnold DL, Narayanan S, Sled JG, Banwell B, Filippi M. Diffusion tensor magnetic resonance imaging in very early onset pediatric multiple sclerosis. Multiple sclerosis (Houndmills, Basingstoke, England). 2016; 22(5):620-7.

Banwell B, Giovannoni G, Hawkes C, Lublin F. Editors' Welcome. Multiple sclerosis and related disorders. 2016; 6:A1-2.

Makhani N, Banwell B, Tellier R, Yea C, McGovern S, O'Mahony J, Ahorro JM, Arnold D, Sadovnick AD, Marrie RA, Bar-Or A. Viral exposures and MS outcome in a prospective cohort of children with acquired demyelination. Multiple sclerosis (Houndmills, Basingstoke, England). 2016; 22(3):385-8.

Filippi M, Rocca MA, Ciccarelli O, De Stefano N, Evangelou N, Kappos L, Rovira A, Sastre-Garriga J, Tintorè M, Frederiksen JL, Gasperini C, Palace J, Reich DS, Banwell B, Montalban X, Barkhof F. MRI criteria for the diagnosis of multiple sclerosis: MAGNIMS consensus guidelines. The Lancet. Neurology. 2016; 15(3):292-303.

Nosadini M, Alper G, Riney CJ, Benson LA, Mohammad SS, Ramanathan S, Nolan M, Appleton R, Leventer RJ, Deiva K, Brilot F, Gorman MP, Waldman AT, Banwell B, Dale RC. Rituximab monitoring and redosing in pediatric neuromyelitis optica spectrum disorder. Neurology(R) neuroimmunology & neuroinflammation. 2016; 3(1):e188.

Akbar N, Giorgio A, Till C, Sled JG, Doesburg SM, De Stefano N, Banwell B. Alterations in Functional and Structural Connectivity in Pediatric-Onset Multiple Sclerosis. PloS one. 2016; 11(1):e0145906.

Akbar N, Banwell B, Sled JG, Binns MA, Doesburg SM, Rypma B, Lysenko M, Till C. Brain activation patterns and cognitive processing speed in patients with pediatric-onset multiple sclerosis. Journal of clinical and experimental neuropsychology. 2016; 38(4):393-403.

Brenton JN, Banwell BL. Therapeutic Approach to the Management of Pediatric Demyelinating Disease: Multiple Sclerosis and Acute Disseminated Encephalomyelitis. Neurotherapeutics: the journal of the American Society for Experimental NeuroTherapeutics. 2016; 13(1):84-95.

Banwell B, Giovannoni G, Hawkes C, Lublin F. Editors' Welcome. Multiple sclerosis and related disorders. 2016; 5:A1.

2015

Grover SA, Aubert-Broche B, Fetco D, Collins DL, Arnold DL, Finlayson M, Banwell BL, Motl RW, Yeh EA. Lower physical activity is associated with higher disease burden in pediatric multiple sclerosis. Neurology. 2015; 85(19):1663-9.

Banwell B, Giovannoni G, Hawkes C, Lublin F. Editors' Welcome. Multiple sclerosis and related disorders. 2015; 4(6):A1-2.

Lucas RM, Banwell B. Do prenatal sex hormones modulate MS risk? Neurology. 2015; 85(14):1193-4.

Banwell B, Giovannoni G, Hawkes C, Lublin F. Editors' Welcome. Multiple sclerosis and related disorders. 2015; 4(5):A1-A2.

Melamed E, Levy M, Waters PJ, Sato DK, Bennett JL, John GR, Hooper DC, Saiz A, Bar-Or A, Kim HJ, Pandit L, Leite MI, Asgari N, Kissani N, Hintzen R, Marignier R, Jarius S, Marcelletti J, Smith TJ, Yeaman MR, Han MH, Aktas O, Apiwattanakul M, Banwell B, Bichuetti D, Broadley S, Cabre P, Chitnis T, De Seze J, Fujihara K, Greenberg B, Hellwig K, Iorio R, Jarius S, Klawiter E, Kleiter I, Lana-Peixoto M, Nakashima, O'Connor K, Palace J, Paul F, Prayoonwiwat N, Ruprecht K, Stuve O, Tedder T, Tenembaum S, Garrahan JP, Aires B, van Herle K, van Pelt D, Villoslada P, Waubant E, Weinshenker B, Wingerchuk D, Würfel J, Zamvil S. Update on biomarkers in neuromyelitis optica. Neurology(R) neuroimmunology & neuroinflammation. 2015; 2(4):e134.

Wingerchuk DM, Banwell B, Bennett JL, Cabre P, Carroll W, Chitnis T, de Seze J, Fujihara K, Greenberg B, Jacob A, Jarius S, Lana-Peixoto M, Levy M, Simon JH, Tenembaum S, Traboulsee AL, Waters P, Wellik KE, Weinshenker BG. International consensus diagnostic criteria for neuromyelitis optica spectrum disorders. Neurology. 2015; 85(2):177-89.

O'Mahony J, Marrie RA, Laporte A, Yeh EA, Bar-Or A, Phan C, Buckley D, Callen D, Connolly MB, Pohl D, Dilenge ME, Bernard G, Lortie A, Lowry N, MacDonald EA, Meek D, Sébire G, Venkateswaran S, Wood E, Yager J, Banwell B. Recovery From Central Nervous System Acute Demyelination in Children. Pediatrics. 2015; 136(1):e115-23.

Kremer S, Renard F, Achard S, Lana-Peixoto MA, Palace J, Asgari N, Klawiter EC, Tenembaum SN, Banwell B, Greenberg BM, Bennett JL, Levy M, Villoslada P, Saiz A, Fujihara K, Chan KH, Schippling S, Paul F, Kim HJ, de Seze J, Wuerfel JT, Cabre P, Marignier R, Tedder T, van Pelt D, Broadley S, Chitnis T, Wingerchuk D, Pandit L, Leite MI, Apiwattanakul M, Kleiter I, Prayoonwiwat N, Han M, Hellwig K, van Herle K, John G, Hooper DC, Nakashima I, Sato D, Yeaman MR, Waubant E, Zamvil S, Stüve O, Aktas O, Smith TJ, Jacob A, O'Connor K. Use of Advanced Magnetic Resonance Imaging Techniques in Neuromyelitis Optica Spectrum Disorder. JAMA neurology. 2015; 72(7):815-22.

Banwell B, Giovannoni G, Hawkes C, Lublin F. Editors' Welcome. Multiple sclerosis and related disorders. 2015; 4(4):A1-3.

Weier K, Banwell B, Cerasa A, Collins DL, Dogonowski AM, Lassmann H, Quattrone A, Sahraian MA, Siebner HR, Sprenger T. The role of the cerebellum in multiple sclerosis. Cerebellum (London, England). 2015; 14(3):364-74.

Bigi S, Banwell B, Yeh EA. Outcomes after early administration of plasma exchange in pediatric central nervous system inflammatory demyelination. Journal of child neurology. 2015; 30(7):874-80.

Ahn JJ, O'Mahony J, Moshkova M, Hanwell HE, Singh H, Zhang MA, Marrie RA, Bar-Or A, Sadovnick DA, Dunn SE, Banwell BL. Puberty in females enhances the risk of an outcome of multiple sclerosis in children and the development of central nervous system autoimmunity in mice. Multiple sclerosis (Houndmills, Basingstoke, England). 2015; 21(6):735-48.

Ghassemi R, Brown R, Banwell B, Narayanan S, Arnold DL. Quantitative Measurement of tissue damage and recovery within new T2w lesions in pediatric- and adult-onset multiple sclerosis. Multiple sclerosis (Houndmills, Basingstoke, England). 2015; 21(6):718-25.

Bennett JL, de Seze J, Lana-Peixoto M, Palace J, Waldman A, Schippling S, Tenembaum S, Banwell B, Greenberg B, Levy M, Fujihara K, Chan KH, Kim HJ, Asgari N, Sato DK, Saiz A, Wuerfel J, Zimmermann H, Green A, Villoslada P, Paul F. Neuromyelitis optica and multiple sclerosis: Seeing differences through optical coherence tomography. Multiple sclerosis (Houndmills, Basingstoke, England). 2015; 21(6):678-88.

Banwell B, Giovannoni G, Hawkes C, Lublin F. Editors' welcome. Multiple sclerosis and related disorders. 2015; 4(3):181.

Sham L, Yeh EA, Magalhaes S, Parra EJ, Gozdzik A, Banwell B, Hanwell HE. Evaluation of fall Sun Exposure Score in predicting vitamin D status in young Canadian adults, and the influence of ancestry. Journal of photochemistry and photobiology. B, Biology. 2015; 145:25-9.

Narula S, Banwell B. Treatment of multiple sclerosis in children and its challenges. Presse medicale (Paris, France : 1983). 2015; 44(4 Pt 2):e153-8.

Narula S, Liu GT, Avery RA, Banwell B, Waldman AT. Elevated cerebrospinal fluid opening pressure in a pediatric demyelinating disease cohort. Pediatric neurology. 2015; 52(4):446-9.

Banwell B, Giovannoni G, Hawkes C, Lublin F. Editors' welcome. Multiple sclerosis and related disorders. 2015; 4(2):93-4.

Kim HJ, Paul F, Lana-Peixoto MA, Tenembaum S, Asgari N, Palace J, Klawiter EC, Sato DK, de Seze J, Wuerfel J, Banwell BL, Villoslada P, Saiz A, Fujihara K, Kim SH. MRI characteristics of neuromyelitis optica spectrum disorder: an international update. Neurology. 2015; 84(11):1165-73.

Narula S, Hopkins SE, Banwell B. Treatment of pediatric multiple sclerosis. Current treatment options in neurology. 2015; 17(3):336.

Ghassemi R, Brown R, Narayanan S, Banwell B, Nakamura K, Arnold DL. Normalization of white matter intensity on T1-weighted images of patients with acquired central nervous system demyelination. Journal of neuroimaging: official journal of the American Society of Neuroimaging. 2015; 25(2):184-190.

Banwell B, Dale RC. Understanding risk of relapse and risk of disability after childhood transverse myelitis. Neurology. 2015; 84(4):332-4.

Banwell B, Giovannoni G, Hawkes C, Lublin F. Editors' welcome. Multiple sclerosis and related disorders. 2015; 4(1):1-2.

Varsani H, Charman SC, Li CK, Marie SK, Amato AA, Banwell B, Bove KE, Corse AM, Emslie-Smith AM, Jacques TS, Lundberg IE, Minetti C, Nennesmo I, Rushing EJ, Sallum AM, Sewry C, Pilkington CA, Holton JL, Wedderburn LR. Validation of a score tool for measurement of histological severity in juvenile dermatomyositis and association with clinical severity of disease. Annals of the rheumatic diseases. 2015; 74(1):204-10. 

2014

Longoni G, Banwell B, Filippi M, Yeh EA. Rituximab as a first-line preventive treatment in pediatric NMOSDs: Preliminary results in 5 children. Neurology(R) neuroimmunology & neuroinflammation. 2014; 1(4):e46.

Quintana FJ, Patel B, Yeste A, Nyirenda M, Kenison J, Rahbari R, Fetco D, Hussain M, O'Mahony J, Magalhaes S, McGowan M, Johnson T, Rajasekharan S, Narayanan S, Arnold DL, Weiner HL, Banwell B, Bar-Or A. Epitope spreading as an early pathogenic event in pediatric multiple sclerosis. Neurology. 2014; 83(24):2219-26.

Aubert-Broche B, Fonov V, Narayanan S, Arnold DL, Araujo D, Fetco D, Till C, Sled JG, Banwell B, Collins DL. Onset of multiple sclerosis before adulthood leads to failure of age-expected brain growth. Neurology. 2014; 83(23):2140-6.

Yeh EA, Marrie RA, Reginald YA, Buncic JR, Noguera AE, O'Mahony J, Mah JK, Banwell B, Costello F. Functional-structural correlations in the afferent visual pathway in pediatric demyelination. Neurology. 2014; 83(23):2147-52.

Banwell B, Giovannoni G, Hawkes C, Lublin F. Editors' welcome. Multiple sclerosis and related disorders. 2014; 3(6):667.

Bigi S, Marrie R, Yeh E, Banwell B. Antinuclear antibodies in pediatric acquired demyelinating diseases of the central nervous system. Multiple sclerosis (Houndmills, Basingstoke, England). 2014; 20(12):1665-6.

Brown RA, Narayanan S, Banwell B, Arnold DL. Magnetization transfer ratio recovery in new lesions decreases during adolescence in pediatric-onset multiple sclerosis patients. NeuroImage. Clinical. 2014; 6:237-42.

Hosseini B, Flora DB, Banwell BL, Till C. Age of onset as a moderator of cognitive decline in pediatric-onset multiple sclerosis. Journal of the International Neuropsychological Society : JINS. 2014; 20(8):796-804.

Banwell B, Giovannoni G, Hawkes C, Lublin F. Multiple Sclerosis is a multifaceted disease. Multiple sclerosis and related disorders. 2014; 3(5):553-4.

Miyazaki Y, Li R, Rezk A, Misirliyan H, Moore C, Farooqi N, Solis M, Goiry LG, de Faria Junior O, Dang VD, Colman D, Dhaunchak AS, Antel J, Gommerman J, Prat A, Fillatreau S, Bar-Or A. A novel microRNA-132-sirtuin-1 axis underlies aberrant B-cell cytokine regulation in patients with relapsing-remitting multiple sclerosis [corrected]. PloS one. 2014; 9(8):e105421.

Macgowan CK, Chan KY, Laughlin S, Marrie RA, Banwell B. Cerebral arterial and venous blood flow in adolescent multiple sclerosis patients and age-matched controls using phase contrast MRI. Journal of magnetic resonance imaging : JMRI. 2014; 40(2):341-7.

Lublin FD, Reingold SC, Cohen JA, Cutter GR, Sørensen PS, Thompson AJ, Wolinsky JS, Balcer LJ, Banwell B, Barkhof F, Bebo B Jr, Calabresi PA, Clanet M, Comi G, Fox RJ, Freedman MS, Goodman AD, Inglese M, Kappos L, Kieseier BC, Lincoln JA, Lubetzki C, Miller AE, Montalban X, O'Connor PW, Petkau J, Pozzilli C, Rudick RA, Sormani MP, Stüve O, Waubant E, Polman CH. Defining the clinical course of multiple sclerosis: the 2013 revisions. Neurology. 2014; 83(3):278-86.

Banwell B, Giovannoni G, Hawkes C, Lublin F. Editors' welcome. Multiple sclerosis and related disorders. 2014; 3(4):417-8.

Schwartz KL, Richardson SE, Ward KN, Donaldson C, MacGregor D, Banwell B, Mahant S, Bitnun A. Delayed primary HHV-7 infection and neurologic disease. Pediatrics. 2014; 133(6):e1541-7.

Kremer L, Mealy M, Jacob A, Nakashima I, Cabre P, Bigi S, Paul F, Jarius S, Aktas O, Elsone L, Mutch K, Levy M, Takai Y, Collongues N, Banwell B, Fujihara K, de Seze J. Brainstem manifestations in neuromyelitis optica: a multicenter study of 258 patients. Multiple sclerosis (Houndmills, Basingstoke, England). 2014; 20(7):843-7.

Yiu EM, Laughlin S, Verhey LH, Banwell BL. Clinical and magnetic resonance imaging (MRI) distinctions between tumefactive demyelination and brain tumors in children. Journal of child neurology. 2014; 29(5):654-65.

Banwell B, Giovannoni G, Hawkes C, Lublin F. Editors' welcome. Multiple sclerosis and related disorders. 2014; 3(3):283.

Banwell B, Giovannoni G, Hawkes C, Lublin F. Editors' welcome. Multiple sclerosis and related disorders. 2014; 3(2):139-40.

Goh ES, Banwell B, Stavropoulos DJ, Shago M, Yoon G. Mosaic microdeletion of 17p11.2-p12 and duplication of 17q22-q24 in a girl with Smith-Magenis phenotype and peripheral neuropathy. American journal of medical genetics. Part A. 2014; 164A(3):748-52.

Ghassemi R, Narayanan S, Banwell B, Sled JG, Shroff M, Arnold DL. Quantitative determination of regional lesion volume and distribution in children and adults with relapsing-remitting multiple sclerosis. PloS one. 2014; 9(2):e85741.

Todorow M, DeSouza JF, Banwell BL, Till C. Interhemispheric cooperation in global-local visual processing in pediatric multiple sclerosis. Journal of clinical and experimental neuropsychology. 2014; 36(2):111-26.

Banwell BL. Multiple sclerosis in children. Handbook of clinical neurology. 2014; 122:427-41. 

Aubert-Broche B, Fonov V, Narayanan S, Arnold DL, Araujo D, Fetco D, Till C, Sled JG, Banwell B, Collins DL; Canadian Pediatric Demyelinating Disease Network. Onset of multiple sclerosis before adulthood leads to failure of age-expected brain growth. Neurology. 2014;83(23):2140-2146.

Dale RC, Brilot F, Duffy LV, Twilt M, Waldman AT, Narula S, Muscal E, Deiva K, Andersen E, Eyre MR, Eleftheriou D, Brogan PA, Kneen R, Alper G, Anlar B, Wassmer E, Heineman K, Hemingway C, Riney CJ, Kornberg A, Tardieu M, Stocco A, Banwell B, Gorman MP, Benseler SM, Lim M. Utility and safety of rituximab in pediatric autoimmune and inflammatory CNS disease. Neurology. 2014;83(2):142-150.

Waldman A, Ghezzi A, Bar-Or A, Mikaeloff Y, Tardieu M, Banwell B. Multiple sclerosis in children: an update on clinical diagnosis, therapeutic strategies, and research. Lancet Neurol. 2014;13(9):936-948.

2013

van Pelt ED, Mescheriakova JY, Makhani N, Ketelslegers IA, Neuteboom RF, Kundu S, Broer L, Janssens C, Catsman-Berrevoets CE, van Duijn CM, Banwell B, Bar-Or A, Hintzen RQ. Risk genes associated with pediatric-onset MS but not with monophasic acquired CNS demyelination. Neurology. 2013; 81(23):1996-2001.

Laughlin S, Macgowan CK, Traubici J, Chan K, Khan S, Arnold DL, Marrie RA, Banwell B. No evidence for impairment of venous hemodynamics in children or young adults with pediatric-onset multiple sclerosis. AJNR. American journal of neuroradiology. 2013; 34(12):2366-72.

Marin SE, Banwell BB, Till C. Cognitive trajectories in 4 patients with pediatric-onset multiple sclerosis: serial evaluation over a decade. Journal of child neurology. 2013; 28(12):1577-86.

Van Haren K, Tomooka BH, Kidd BA, Banwell B, Bar-Or A, Chitnis T, Tenembaum SN, Pohl D, Rostasy K, Dale RC, O'Connor KC, Hafler DA, Steinman L, Robinson WH. Serum autoantibodies to myelin peptides distinguish acute disseminated encephalomyelitis from relapsing-remitting multiple sclerosis. Multiple sclerosis (Houndmills, Basingstoke, England). 2013; 19(13):1726-33.

Yoon G, Baskin B, Tarnopolsky M, Boycott KM, Geraghty MT, Sell E, Goobie S, Meschino W, Banwell B, Ray PN. Autosomal recessive hereditary spastic paraplegia-clinical and genetic characteristics of a well-defined cohort. Neurogenetics. 2013; 14(3-4):181-8.

Ruzzo EK, Capo-Chichi JM, Ben-Zeev B, Chitayat D, Mao H, Pappas AL, Hitomi Y, Lu YF, Yao X, Hamdan FF, Pelak K, Reznik-Wolf H, Bar-Joseph I, Oz-Levi D, Lev D, Lerman-Sagie T, Leshinsky-Silver E, Anikster Y, Ben-Asher E, Olender T, Colleaux L, Décarie JC, Blaser S, Banwell B, Joshi RB, He XP, Patry L, Silver RJ, Dobrzeniecka S, Islam MS, Hasnat A, Samuels ME, Aryal DK, Rodriguiz RM, Jiang YH, Wetsel WC, McNamara JO, Rouleau GA, Silver DL, Lancet D, Pras E, Mitchell GA, Michaud JL, Goldstein DB. Deficiency of asparagine synthetase causes congenital microcephaly and a progressive form of encephalopathy. Neuron. 2013; 80(2):429-41.

Yea C, Tellier R, Chong P, Westmacott G, Marrie RA, Bar-Or A, Banwell B. Epstein-Barr virus in oral shedding of children with multiple sclerosis. Neurology. 2013; 81(16):1392-9.

Verhey LH, Signori A, Arnold DL, Bar-Or A, Sadovnick AD, Marrie RA, Banwell B, Sormani MP. Clinical and MRI activity as determinants of sample size for pediatric multiple sclerosis trials. Neurology. 2013; 81(14):1215-21.

Mayer MC, Breithaupt C, Reindl M, Schanda K, Rostásy K, Berger T, Dale RC, Brilot F, Olsson T, Jenne D, Pröbstel AK, Dornmair K, Wekerle H, Hohlfeld R, Banwell B, Bar-Or A, Meinl E. Distinction and temporal stability of conformational epitopes on myelin oligodendrocyte glycoprotein recognized by patients with different inflammatory central nervous system diseases. Journal of immunology (Baltimore, Md.: 1950). 2013; 191(7):3594-604.

Banwell B, Giovannoni G, Hawkes CH, Lublin F. Promoting regeneration and repair in Multiple Sclerosis. Multiple sclerosis and related disorders. 2013; 2(4):261-2.

Krupp LB, Tardieu M, Amato MP, Banwell B, Chitnis T, Dale RC, Ghezzi A, Hintzen R, Kornberg A, Pohl D, Rostasy K, Tenembaum S, Wassmer E. International Pediatric Multiple Sclerosis Study Group criteria for pediatric multiple sclerosis and immune-mediated central nervous system demyelinating disorders: revisions to the 2007 definitions. Multiple sclerosis (Houndmills, Basingstoke, England). 2013; 19(10):1261-7.

Bigi S, Marrie RA, Verhey L, Yeh EA, Banwell B. 2010 McDonald criteria in a pediatric cohort: is positivity at onset associated with a more aggressive multiple sclerosis course? Multiple sclerosis (Houndmills, Basingstoke, England). 2013; 19(10):1359-62.

Verhey LH, van Pelt-Gravesteijn ED, Ketelslegers IA, Neuteboom RF, Catsman-Berrevoets CE, Feldman BM, Streiner DL, Sled JG, Hintzen RQ, Banwell B. Validation of MRI predictors of multiple sclerosis diagnosis in children with acute CNS demyelination. Multiple sclerosis and related disorders. 2013; 2(3):193-9.

Banwell B, Giovannoni G, Hawkes C, Lublin F. Editorial. Multiple sclerosis and related disorders. 2013; 2(3):153.

Tenembaum SN, Banwell B, Pohl D, Krupp LB, Boyko A, Meinel M, Lehr L, Rocak S, Cantogno EV, Moraga MS, Ghezzi A. Subcutaneous interferon Beta-1a in pediatric multiple sclerosis: a retrospective study. Journal of child neurology. 2013; 28(7):849-56.

Verhey LH, Branson HM, Laughlin S, Shroff MM, Benseler SM, Feldman BM, Streiner DL, Sled JG, Banwell B. Development of a standardized MRI scoring tool for CNS demyelination in children. AJNR. American journal of neuroradiology. 2013; 34(6):1271-7.

O'Mahony J, Shroff M, Banwell B. Mimics and rare presentations of pediatric demyelination. Neuroimaging clinics of North America. 2013; 23(2):321-36.

Makhani N, Bigi S, Banwell B, Shroff M. Diagnosing neuromyelitis optica. Neuroimaging clinics of North America. 2013; 23(2):279-91.

Verhey LH, Shroff M, Banwell B. Pediatric multiple sclerosis: pathobiological, clinical, and magnetic resonance imaging features. Neuroimaging clinics of North America. 2013; 23(2):227-43.

Verhey LH, Narayanan S, Banwell B. Standardized magnetic resonance imaging acquisition and reporting in pediatric multiple sclerosis. Neuroimaging clinics of North America. 2013; 23(2):217-26.e1-7.

Freedman MS, Selchen D, Arnold DL, Prat A, Banwell B, Yeung M, Morgenthau D, Lapierre Y. Treatment optimization in MS: Canadian MS Working Group updated recommendations. The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques. 2013; 40(3):307-23.

Banwell B, Giovannoni G, Hawkes C, Lublin F. Editors' welcome and a working definition for a multiple sclerosis cure. Multiple sclerosis and related disorders. 2013; 2(2):65-7.

Chitnis T, Tardieu M, Amato MP, Banwell B, Bar-Or A, Ghezzi A, Kornberg A, Krupp LB, Pohl D, Rostasy K, Tenembaum S, Waubant E, Wassmer E. International Pediatric MS Study Group Clinical Trials Summit: meeting report. Neurology. 2013; 80(12):1161-8.

Naismith RT, Banwell BL. Can "dissemination" include the PNS in adults with acute disseminated encephalomyelitis? Neurology. 2013; 80(10):876-7.

Till C, Racine N, Araujo D, Narayanan S, Collins DL, Aubert-Broche B, Arnold DL, Banwell B. Changes in cognitive performance over a 1-year period in children and adolescents with multiple sclerosis. Neuropsychology. 2013; 27(2):210-9.

O'Mahony J, Bar-Or A, Arnold DL, Sadovnick AD, Marrie RA, Banwell B. Masquerades of acquired demyelination in children: experiences of a national demyelinating disease program. Journal of child neurology. 2013; 28(2):184-97.

Belabani C, Rajasekharan S, Poupon V, Johnson T, Bar-Or A. A condensed performance-validation strategy for multiplex detection kits used in studies of human clinical samples. Journal of immunological methods. 2013; 387(1-2):1-10.

Banwell BL. Pediatric multiple sclerosis. Handbook of clinical neurology. 2013; 112:1263-74.

Verhey LH, Banwell BL. Inflammatory, vascular, and infectious myelopathies in children. Handbook of clinical neurology. 2013; 112:999-1017.

Kimball S, Hanwell HE, Banwell B. Invited Review: Vitamin D in the Prevention and Treatment of Multiple Sclerosis. Function Food Reviews. 2013; 3(3).

Venkateswaran S, Banwell B. Clinical Trials in pediatric multiple sclerosis: overcoming the challenges. Clinical Investigation. 2013; 3(1):307-23.

2012

Bigi S, Banwell B. Pediatric multiple sclerosis. Journal of child neurology. 2012; 27(11):1378-83.

Batthish M, Banwell B, Laughlin S, Halliday W, Peschken C, Paras E, Benseler S. Refractory primary central nervous system vasculitis of childhood: successful treatment with infliximab. The Journal of rheumatology. 2012; 39(11):2227-9.

Banwell B, Giovannoni G, Hawkes C, Lublin F. Editors' welcome. Multiple sclerosis and related disorders. 2012; 1(4):153.

Sadaka Y, Verhey LH, Shroff MM, Branson HM, Arnold DL, Narayanan S, Sled JG, Bar-Or A, Sadovnick AD, McGowan M, Marrie RA, Banwell B. 2010 McDonald criteria for diagnosing pediatric multiple sclerosis. Annals of neurology. 2012; 72(2):211-23.

Till C, Ho C, Dudani A, García-Lorenzo D, Collins DL, Banwell BL. Magnetic resonance imaging predictors of executive functioning in patients with pediatric-onset multiple sclerosis. Archives of clinical neuropsychology: the official journal of the National Academy of Neuropsychologists. 2012; 27(5):495-509.

Till C, Udler E, Ghassemi R, Narayanan S, Arnold DL, Banwell BL. Factors associated with emotional and behavioral outcomes in adolescents with multiple sclerosis. Multiple sclerosis (Houndmills, Basingstoke, England). 2012; 18(8):1170-80.

Rajasekharan S, Bar-Or A. From bench to MS bedside: challenges translating biomarker discovery to clinical practice. Journal of neuroimmunology. 2012; 248(1-2):66-72.

Dale RC, Banwell B, Bar-Or A, Brilot F. Autoantibodies against aquaporin-4 and myelin oligodendrocyte glycoprotein in paediatric CNS demyelination: Recent developments and future directions. Multiple sclerosis and related disorders. 2012; 1(3):116-22.

Cohen JA, Reingold SC, Polman CH, Wolinsky JS. Disability outcome measures in multiple sclerosis clinical trials: current status and future prospects. The Lancet. Neurology. 2012; 11(5):467-76.

Dhaunchak AS, Becker C, Schulman H, De Faria O Jr, Rajasekharan S, Banwell B, Colman DR, Bar-Or A. Implication of perturbed axoglial apparatus in early pediatric multiple sclerosis. Annals of neurology. 2012; 71(5):601-13.

Fuentes A, Collins DL, Garcia-Lorenzo D, Sled JG, Narayanan S, Arnold DL, Banwell BL, Till C. Memory performance and normalized regional brain volumes in patients with pediatric-onset multiple sclerosis. Journal of the International Neuropsychological Society : JINS. 2012; 18(3):471-80.

Banwell B, Dale RC. Lymphohistiocytosis in the brain: recognition of a potentially reversible aspect of primary HLH. Neurology. 2012; 78(15):1114-5.

Banwell B, Giovannoni G, Hawkes C, Lublin F. Editors' welcome. Multiple sclerosis and related disorders. 2012; 1(2):55.

Kerbrat A, Aubert-Broche B, Fonov V, Narayanan S, Sled JG, Arnold DA, Banwell B, Collins DL.. Reduced head and brain size for age and disproportionately smaller thalami in child-onset MS. Neurology. 2012; 78(3):194-201.

Banwell B. Multiple sclerosis in children. Multiple sclerosis and related disorders. 2012; 1(1):3-5.

Banwell B, Giovannoni G, Hawkes C, Lublin F. Editor's Welcome. Multiple sclerosis and related disorders. 2012; 1(1):1-2.

Chitnis T, Tenembaum S, Banwell B, Krupp L, Pohl D, Rostasy K, Yeh EA, Bykova O, Wassmer E, Tardieu M, Kornberg A, Ghezzi A. Consensus statement: evaluation of new and existing therapeutics for pediatric multiple sclerosis. Multiple sclerosis (Houndmills, Basingstoke, England). 2012; 18(1):116-27.

Kuni BJ, Banwell BL, Till C. Cognitive and behavioral outcomes in individuals with a history of acute disseminated encephalomyelitis (ADEM). Developmental neuropsychology. 2012; 37(8):682-96.

Thomas T, Branson HM, Verhey LH, Shroff M, Stephens D, Magalhaes S, Banwell B. The demographic, clinical, and magnetic resonance imaging (MRI) features of transverse myelitis in children. Journal of child neurology. 2012; 27(1):11-21.

2011

Till C, Deotto A, Tipu V, Sled JG, Bethune A, Narayanan S, Arnold DL, Banwell BL. White matter integrity and math performance in pediatric multiple sclerosis: a diffusion tensor imaging study. NeuroReport. 2011; 22(18):1005-9.

Verhey LH, Branson HM, Shroff MM, Callen DJ, Sled JG, Narayanan S, Sadovnick AD, Bar-Or A, Arnold DL, Marrie RA, Banwell B. MRI parameters for prediction of multiple sclerosis diagnosis in children with acute CNS demyelination: a prospective national cohort study. The Lancet. Neurology. 2011; 10(12):1065-73.

Bethune A, Tipu V, Sled JG, Narayanan S, Arnold DL, Mabbott D, Rockel C, Ghassemi R, Till C, Banwell B. Diffusion tensor imaging and cognitive speed in children with multiple sclerosis. Journal of the neurological sciences. 2011; 309(1-2):68-74.

Waldman AT, Banwell BL. Acquiring new insights: incidence of acquired demyelination and MS in US children. Neurology. 2011; 77(12):1112-3

Aubert-Broche B, Fonov V, Ghassemi R, Narayanan S, Arnold DL, Banwell B, Sled JG, Collins DL. Regional brain atrophy in children with multiple sclerosis. NeuroImage. 2011; 58(2):409-15.

Pröbstel AK, Dornmair K, Bittner R, Sperl P, Jenne D, Magalhaes S, Villalobos A, Breithaupt C, Weissert R, Jacob U, Krumbholz M, Kuempfel T, Blaschek A, Stark W, Gärtner J, Pohl D, Rostasy K, Weber F, Forne I, Khademi M, Olsson T, Brilot F, Tantsis E, Dale RC, Wekerle H, Hohlfeld R, Banwell B, Bar-Or A, Meinl E, Derfuss T. Antibodies to MOG are transient in childhood acute disseminated encephalomyelitis. Neurology. 2011; 77(6):580-8.

Morin MP, Patenaude Y, Sinsky AB, Banwell B, Sébire G. Solitary tumefactive demyelinating lesions in children. Journal of child neurology. 2011; 26(8):995-9.

Makhani N, Banwell B. Noninfectious central nervous system inflammatory disorders. Seminars in pediatric neurology. 2011; 18(2):91-4.

Till C, Ghassemi R, Aubert-Broche B, Kerbrat A, Collins DL, Narayanan S, Arnold DL, Desrocher M, Sled JG, Banwell BL. MRI correlates of cognitive impairment in childhood-onset multiple sclerosis. Neuropsychology. 2011; 25(3):319-32.

Banwell B, Bar-Or A, Arnold DL, Sadovnick D, Narayanan S, McGowan M, O'Mahony J, Magalhaes S, Hanwell H, Vieth R, Tellier R, Vincent T, Disanto G, Ebers G, Wambera K, Connolly MB, Yager J, Mah JK, Booth F, Sebire G, Callen D, Meaney B, Dilenge ME, Lortie A, Pohl D, Doja A, Venketaswaran S, Levin S, Macdonald EA, Meek D, Wood E, Lowry N, Buckley D, Yim C, Awuku M, Cooper P, Grand'maison F, Baird JB, Bhan V, Marrie RA. Clinical, environmental, and genetic determinants of multiple sclerosis in children with acute demyelination: a prospective national cohort study. The Lancet. Neurology. 2011; 10(5):436-45.

Disanto G, Magalhaes S, Handel AE, Morrison KM, Sadovnick AD, Ebers GC, Banwell B, Bar-Or A. HLA-DRB1 confers increased risk of pediatric-onset MS in children with acquired demyelination. Neurology. 2011; 76(9):781-6.

Venkateswaran S, Zheng K, Sacchetti M, Gagne D, Arnold DL, Sadovnick AD, Scherer SW, Banwell B, Bar-Or A, Simon DK. Mitochondrial DNA haplogroups and mutations in children with acquired central demyelination. Neurology. 2011; 76(9):774-80.

Banwell B, Bar-Or A, Giovannoni G, Dale RC, Tardieu M. Therapies for multiple sclerosis: considerations in the pediatric patient. Nature reviews. Neurology. 2011; 7(2):109-22.

Hanwell HE, Banwell B. Assessment of evidence for a protective role of vitamin D in multiple sclerosis. Biochimica et biophysica acta. 2011; 1812(2):202-12.

Polman CH, Reingold SC, Banwell B, Clanet M, Cohen JA, Filippi M, Fujihara K, Havrdova E, Hutchinson M, Kappos L, Lublin FD, Montalban X, O'Connor P, Sandberg-Wollheim M, Thompson AJ, Waubant E, Weinshenker B, Wolinsky JS. Diagnostic criteria for multiple sclerosis: 2010 revisions to the McDonald criteria. Annals of neurology. 2011; 69(2):292-302.

Makhani N, Morris SK, Page AV, Brophy J, Lindsay LR, Banwell BL, Richardson SE. A twist on Lyme: the challenge of diagnosing European Lyme neuroborreliosis. Journal of clinical microbiology. 2011; 49(1):455-7.

Makhani N, Banwell B. Environmental Risk Factors for Pediatric Multiple Sclerosis. European neurological review. 2011; 6(3):175-80.

2010

Katz SL, Gaboury I, Keilty K, Banwell B, Vajsar J, Anderson P, Ni A, Maclusky I. Nocturnal hypoventilation: predictors and outcomes in childhood progressive neuromuscular disease. Archives of disease in childhood. 2010; 95(12):998-1003.

Verhey LH, Branson HM, Makhija M, Shroff M, Banwell B. Magnetic resonance imaging features of the spinal cord in pediatric multiple sclerosis: a preliminary study. Neuroradiology. 2010; 52(12):1153-62.

Ghezzi A, Banwell B, Boyko A, Amato MP, Anlar B, Blinkenberg M, Boon M, Filippi M, Jozwiak S, Ketelslegers I, Kornek B, Lim M, Lindstrom E, Nadj C, Neuteboom R, Rocca MA, Rostasy K, Tardieu M, Wassmer E, Catsman-Berrevoets C, Hintzen R. The management of multiple sclerosis in children: a European view. Multiple sclerosis (Houndmills, Basingstoke, England). 2010; 16(10):1258-67.

Yiu EM, Banwell B. Update on emerging therapies for multiple sclerosis. Expert review of neurotherapeutics. 2010; 10(8):1259-62.

Cheng A, Banwell B, Levin S, Seabrook JA, Freeman D, Rieder M. Oral dosing requirements for phenytoin in the first three months of life. Journal of population therapeutics and clinical pharmacology = Journal de la therapeutique des populations et de la pharamcologie clinique. 2010; 17(2):e256-61.

Malik V, Rodino-Klapac LR, Viollet L, Wall C, King W, Al-Dahhak R, Lewis S, Shilling CJ, Kota J, Serrano-Munuera C, Hayes J, Mahan JD, Campbell KJ, Banwell B, Dasouki M, Watts V, Sivakumar K, Bien-Willner R, Flanigan KM, Sahenk Z, Barohn RJ, Walker CM, Mendell JR. Gentamicin-induced readthrough of stop codons in Duchenne muscular dystrophy. Annals of neurology. 2010; 67(6):771-80.

O'Connor KC, Lopez-Amaya C, Gagne D, Lovato L, Moore-Odom NH, Kennedy J, Krupp L, Tenembaum S, Ness J, Belman A, Boyko A, Bykova O, Mah JK, Stoian CA, Waubant E, Kremenchutzky M, Ruggieri M, Bardini MR, Rensel M, Hahn J, Weinstock-Guttman B, Yeh EA, Farrell K, Freedman MS, Iivanainen M, Bhan V, Dilenge M, Hancock MA, Gano D, Fattahie R, Kopel L, Fournier AE, Moscarello M, Banwell B, Bar-Or A. Anti-myelin antibodies modulate clinical expression of childhood multiple sclerosis. Journal of neuroimmunology. 2010; 223(1-2):92-9.

Quercia N, Somers GR, Halliday W, Kantor PF, Banwell B, Yoon G. Friedreich ataxia presenting as sudden cardiac death in childhood: clinical, genetic and pathological correlation, with implications for genetic testing and counseling. Neuromuscular disorders: NMD. 2010; 20(5):340-2.

Venkateswaran S, Banwell B. Pediatric multiple sclerosis. The neurologist. 2010; 16(2):92-105.

Miller E, Widjaja E, Nilsson D, Yoon G, Banwell B, Blaser S. Magnetic resonance imaging of a unique mutation in a family with Pelizaeus-Merzbacher disease. American journal of medical genetics. Part A. 2010; 152A(3):748-52.

McMillan HJ, Campbell C, Mah JK. Duchenne muscular dystrophy: Canadian paediatric neuromuscular physicians survey. The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques. 2010; 37(2):195-205.

2009

McLaughlin KA, Chitnis T, Newcombe J, Franz B, Kennedy J, McArdel S, Kuhle J, Kappos L, Rostasy K, Pohl D, Gagne D, Ness JM, Tenembaum S, O'Connor KC, Viglietta V, Wong SJ, Tavakoli NP, de Seze J, Idrissova Z, Khoury SJ, Bar-Or A, Hafler DA, Banwell B, Wucherpfennig KW. Age-dependent B cell autoimmunity to a myelin surface antigen in pediatric multiple sclerosis. Journal of immunology (Baltimore, Md.: 1950). 2009; 183(6):4067-76.

Maegawa GH, Banwell BL, Blaser S, Sorge G, Toplak M, Ackerley C, Hawkins C, Hayes J, Clarke JT. Substrate reduction therapy in juvenile GM2 gangliosidosis. Molecular genetics and metabolism. 2009; 98(1-2):215-24.

Maegawa GH, van Giersbergen PL, Yang S, Banwell B, Morgan CP, Dingemanse J, Tifft CJ, Clarke JT. Pharmacokinetics, safety and tolerability of miglustat in the treatment of pediatric patients with GM2 gangliosidosis. Molecular genetics and metabolism. 2009; 97(4):284-91.

Makhani N, Gorman MP, Branson HM, Stazzone L, Banwell BL, Chitnis T. Cyclophosphamide therapy in pediatric multiple sclerosis. Neurology. 2009; 72(24):2076-82.

Dale RC, Brilot F, Banwell B. Pediatric central nervous system inflammatory demyelination: acute disseminated encephalomyelitis, clinically isolated syndromes, neuromyelitis optica, and multiple sclerosis. Current opinion in neurology. 2009; 22(3):233-40.

Callen DJ, Shroff MM, Branson HM, Lotze T, Li DK, Stephens D, Banwell BL. Role of MRI in the differentiation of ADEM from MS in children. Neurology. 2009; 72(11):968-73.

Baskin B, Banwell B, Khater RA, Hawkins C, Ray PN. Becker muscular dystrophy caused by an intronic mutation reducing the efficiency of the splice donor site of intron 26 of the dystrophin gene. Neuromuscular disorders : NMD. 2009; 19(3):189-92.

Yoon G, Westmacott R, Macmillan L, Quercia N, Koutsou P, Georghiou A, Christodoulou K, Banwell B. Complete deletion of the aprataxin gene: ataxia with oculomotor apraxia type 1 with severe phenotype and cognitive deficit. BMJ case reports. 2009; 2009.

Banwell B, Kennedy J, Sadovnick D, Arnold DL, Magalhaes S, Wambera K, Connolly MB, Yager J, Mah JK, Shah N, Sebire G, Meaney B, Dilenge ME, Lortie A, Whiting S, Doja A, Levin S, MacDonald EA, Meek D, Wood E, Lowry N, Buckley D, Yim C, Awuku M, Guimond C, Cooper P, Grand'Maison F, Baird JB, Bhan V, Bar-Or A. Incidence of acquired demyelination of the CNS in Canadian children. Neurology. 2009; 72(3):232-9.

2008

Miller DH, Weinshenker BG, Filippi M, Banwell BL, Cohen JA, Freedman MS, Galetta SL, Hutchinson M, Johnson RT, Kappos L, Kira J, Lublin FD, McFarland HF, Montalban X, Panitch H, Richert JR, Reingold SC, Polman CH. Differential diagnosis of suspected multiple sclerosis: a consensus approach. Multiple sclerosis (Houndmills, Basingstoke, England). 2008; 14(9):1157-74.

Banwell BL. Into the looking glass: predicting MS in children experiencing a first demyelinating event. Neurology. 2008; 71(13):962-3.

Banwell BL, Sled JG. Starting early: MRI evidence of gray matter atrophy in children with multiple sclerosis. Neurology. 2008; 70(13 Pt 2):1065-6.

Ghassemi R, Antel SB, Narayanan S, Francis SJ, Bar-Or A, Sadovnick AD, Banwell B, Arnold DL. Lesion distribution in children with clinically isolated syndromes. Annals of neurology. 2008; 63(3):401-5.

Thomas T, Banwell B. Multiple sclerosis in children. Seminars in neurology. 2008; 28(1):69-83.

Yoon G, Westmacott R, MacMillan L, Quercia N, Koutsou P, Georghiou A, Christodoulou K, Banwell B. Complete deletion of the aprataxin gene: ataxia with oculomotor apraxia type 1 with severe phenotype and cognitive deficit. Journal of neurology, neurosurgery, and psychiatry. 2008; 79(2):234-6.

Banwell B, Tenembaum S, Lennon VA, Ursell E, Kennedy J, Bar-Or A, Weinshenker BG, Lucchinetti CF, Pittock SJ. Neuromyelitis optica-IgG in childhood inflammatory demyelinating CNS disorders. Neurology. 2008; 70(5):344-52.

Banwell BL. Through the eyes of a child: research insights gained through the study of childhood multiple sclerosis. Multiple sclerosis (Houndmills, Basingstoke, England). 2008; 14(1):4-5.

Banwell B, Bar-Or A, Cheung R, Kennedy J, Krupp LB, Becker DJ, Dosch HM. Abnormal T-cell reactivities in childhood inflammatory demyelinating disease and type 1 diabetes. Annals of neurology. 2008; 63(1):98-111.

2007

Wedderburn LR, Varsani H, Li CK, Newton KR, Amato AA, Banwell B, Bove KE, Corse AM, Emslie-Smith A, Harding B, Hoogendijk J, Lundberg IE, Marie S, Minetti C, Nennesmo I, Rushing EJ, Sewry C, Charman SC, Pilkington CA, Holton JL. International consensus on a proposed score system for muscle biopsy evaluation in patients with juvenile dermatomyositis: a tool for potential use in clinical trials. Arthritis and rheumatism. 2007; 57(7):1192-201.

Banwell B, Ghezzi A, Bar-Or A, Mikaeloff Y, Tardieu M. Multiple sclerosis in children: clinical diagnosis, therapeutic strategies, and future directions. The Lancet. Neurology. 2007; 6(10):887-902.

Banwell B, Krupp L, Kennedy J, Tellier R, Tenembaum S, Ness J, Belman A, Boiko A, Bykova O, Waubant E, Mah JK, Stoian C, Kremenchutzky M, Bardini MR, Ruggieri M, Rensel M, Hahn J, Weinstock-Guttman B, Yeh EA, Farrell K, Freedman M, Iivanainen M, Sevon M, Bhan V, Dilenge ME, Stephens D, Bar-Or A. Clinical features and viral serologies in children with multiple sclerosis: a multinational observational study. The Lancet. Neurology. 2007; 6(9):773-81.

Banwell BL. The long (-itudinally extensive) and the short of it: transverse myelitis in children. Neurology. 2007; 68(18):1447-9.

Krupp LB, Banwell B, Tenembaum S. Consensus definitions proposed for pediatric multiple sclerosis and related disorders. Neurology. 2007; 68(16 Suppl 2):S7-12.

Pohl D, Waubant E, Banwell B, Chabas D, Chitnis T, Weinstock-Guttman B, Tenembaum S. Treatment of pediatric multiple sclerosis and variants. Neurology. 2007; 68(16 Suppl 2):S54-65.

Banwell B, Shroff M, Ness JM, Jeffery D, Schwid S, Weinstock-Guttman B. MRI features of pediatric multiple sclerosis. Neurology. 2007; 68(16 Suppl 2):S46-53.

Ness JM, Chabas D, Sadovnick AD, Pohl D, Banwell B, Weinstock-Guttman B. Clinical features of children and adolescents with multiple sclerosis. Neurology. 2007; 68(16 Suppl 2):S37-45.

Tenembaum S, Chitnis T, Ness J, Hahn JS. Acute disseminated encephalomyelitis. Neurology. 2007; 68(16 Suppl 2):S23-36.

Belman AL, Chitnis T, Renoux C, Waubant E. Challenges in the classification of pediatric multiple sclerosis and future directions. Neurology. 2007; 68(16 Suppl 2):S70-4.

Feasby T, Banwell B, Benstead T, Bril V, Brouwers M, Freedman M, Hahn A, Hume H, Freedman J, Pi D, Wadsworth L. Guidelines on the use of intravenous immune globulin for neurologic conditions. Transfusion medicine reviews. 2007; 21(2 Suppl 1):S57-107.

O'Connor KC, McLaughlin KA, De Jager PL, Chitnis T, Bettelli E, Xu C, Robinson WH, Cherry SV, Bar-Or A, Banwell B, Fukaura H, Fukazawa T, Tenembaum S, Wong SJ, Tavakoli NP, Idrissova Z, Viglietta V, Rostasy K, Pohl D, Dale RC, Freedman M, Steinman L, Buckle GJ, Kuchroo VK, Hafler DA, Wucherpfennig KW. Self-antigen tetramers discriminate between myelin autoantibodies to native or denatured protein. Nature medicine. 2007; 13(2):211-7.

Banwell B. Response. Pediatric Neurology. 2007; 36(4):278.

Payne ET, Rutka JT, Ho TK, Halliday WC, Banwell BL. Treatment leading to dramatic recovery in acute hemorrhagic leukoencephalitis. Journal of child neurology. 2007; 22(1):109-13.

2006

Maegawa GH, Stockley T, Tropak M, Banwell B, Blaser S, Kok F, Giugliani R, Mahuran D, Clarke JT. The natural history of juvenile or subacute GM2 gangliosidosis: 21 new cases and literature review of 134 previously reported. Pediatrics. 2006; 118(5):e1550-62.

Saengpattrachai M, Ray PN, Hawkins CE, Berzen A, Banwell BL. Grandpa and I have dystrophinopathy?: approach to asymptomatic hyperCKemia. Pediatric neurology. 2006; 35(2):145-9.

Tétreault M, Duquette A, Thiffault I, Bherer C, Jarry J, Loisel L, Banwell B, D'Anjou G, Mathieu J, Robitaille Y, Vanasse M, Brais B. A new form of congenital muscular dystrophy with joint hyperlaxity maps to 3p23-21. Brain: a journal of neurology. 2006; 129(Pt 8):2077-84.

Wilejto M, Shroff M, Buncic JR, Kennedy J, Goia C, Banwell B. The clinical features, MRI findings, and outcome of optic neuritis in children. Neurology. 2006; 67(2):258-62.

Banwell B, Reder AT, Krupp L, Tenembaum S, Eraksoy M, Alexey B, Pohl D, Freedman M, Schelensky L, Antonijevic I. Safety and tolerability of interferon beta-1b in pediatric multiple sclerosis. Neurology. 2006; 66(4):472-6.

Kennedy J, O'Connor P, Sadovnick AD, Perara M, Yee I, Banwell B. Age at onset of multiple sclerosis may be influenced by place of residence during childhood rather than ancestry. Neuroepidemiology. 2006; 26(3):162-7.

Banwell B. Genetic studies in childhood MS. MS in Focus. 2006; :16.

2005

Oddis CV, Rider LG, Reed AM, Ruperto N, Brunner HI, Koneru B, Feldman BM, Giannini EH, Miller FW. International consensus guidelines for trials of therapies in the idiopathic inflammatory myopathies. Arthritis and rheumatism. 2005; 52(9):2607-15.

Banwell B. Treatment of children and adolescents with multiple sclerosis. Expert review of neurotherapeutics. 2005; 5(3):391-401.

Al-Futaisi A, Banwell B, Ochi A, Hew J, Chu B, Oishi M, Otsubo H. Hidden focal EEG seizures during prolonged suppressions and high-amplitude bursts in early infantile epileptic encephalopathy. Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology. 2005; 116(5):1113-7.

Banwell BL, Anderson PE. The cognitive burden of multiple sclerosis in children. Neurology. 2005; 64(5):891-4.

Banwell B, Tremlett H. Coming of age: the use of immunomodulatory therapy in children with multiple sclerosis. Neurology. 2005; 64(5):778-9.

van der Knaap MS, Salomons GS, Li R, Franzoni E, Gutiérrez-Solana LG, Smit LM, Robinson R, Ferrie CD, Cree B, Reddy A, Thomas N, Banwell B, Barkhof F, Jakobs C, Johnson A, Messing A, Brenner M. Unusual variants of Alexander's disease. Annals of neurology. 2005; 57(3):327-38.

Li R, Johnson AB, Salomons G, Goldman JE, Naidu S, Quinlan R, Cree B, Ruyle SZ, Banwell B, D'Hooghe M, Siebert JR, Rolf CM, Cox H, Reddy A, Gutiérrez-Solana LG, Collins A, Weller RO, Messing A, van der Knaap MS, Brenner M. Glial fibrillary acidic protein mutations in infantile, juvenile, and adult forms of Alexander disease. Annals of neurology. 2005; 57(3):310-26.

2004

Banwell BL. Pediatric multiple sclerosis. Current neurology and neuroscience reports. 2004; 4(3):245-52.

Alotaibi S, Kennedy J, Tellier R, Stephens D, Banwell B. Epstein-Barr virus in pediatric multiple sclerosis. JAMA. 2004; 291(15):1875-9.

Hahn CD, Shroff MM, Blaser SI, Banwell BL. MRI criteria for multiple sclerosis: Evaluation in a pediatric cohort. Neurology. 2004; 62(5):806-8.

Banwell BL, Ohno K, Sieb JP, Engel AG. Novel truncating RAPSN mutations causing congenital myasthenic syndrome responsive to 3,4-diaminopyridine. Neuromuscular disorders: NMD. 2004; 14(3):202-7.

Lo B, Faiyaz-Ul-Haque M, Banwell B, Blaser S, Paterson AD, Tsui LC, Teebi AS. The locus responsible for horizontal gaze palsy/progressive scoliosis and brainstem hypoplasia is refined to a 9-cM region on chromosome 11q23. Clinical genetics. 2004; 65(2):137-42.

2003

Banwell BL, Mildner RJ, Hassall AC, Becker LE, Vajsar J, Shemie SD. Muscle weakness in critically ill children. Neurology. 2003; 61(12):1779-82.

Hahn CD, Miles BS, MacGregor DL, Blaser SI, Banwell BL, Hetherington CR. Neurocognitive outcome after acute disseminated encephalomyelitis. Pediatric neurology. 2003; 29(2):117-23.

Pan Y, Zvaritch E, Tupling AR, Rice WJ, de Leon S, Rudnicki M, McKerlie C, Banwell BL, MacLennan DH. Targeted disruption of the ATP2A1 gene encoding the sarco(endo)plasmic reticulum Ca2+ ATPase isoform 1 (SERCA1) impairs diaphragm function and is lethal in neonatal mice. The Journal of biological chemistry. 2003; 278(15):13367-75.

Lamperti C, Naini A, Hirano M, De Vivo DC, Bertini E, Servidei S, Valeriani M, Lynch D, Banwell B, Berg M, Dubrovsky T, Chiriboga C, Angelini C, Pegoraro E, DiMauro S. Cerebellar ataxia and coenzyme Q10 deficiency. Neurology. 2003; 60(7):1206-8.

2002

Minassian BA, Aiyar R, Alic S, Banwell B, Villanova M, Fardeau M, Mandell JW, Juel VC, Rafii M, Auranen M, Kalimo H. Narrowing in on the causative defect of an intriguing X-linked myopathy with excessive autophagy. Neurology. 2002; 59(4):596-601.

Banwell BL. Clinicopathologic conference: loss of milestones and failure to thrive in a 28-month-old boy. The Journal of pediatrics. 2002; 140(6):759-65.

McAdam LC, Blaser SI, Banwell BL. Pediatric tumefactive demyelination: case series and review of the literature. Pediatric neurology. 2002; 26(1):18-25.

2001

Chow GC, Clarke JT, Banwell BL. Late-onset GM2 gangliosidosis presenting as burning dysesthesias. Pediatric neurology. 2001; 25(1):59-61.

Banwell BL. Intermediate filament-related myopathies. Pediatric neurology. 2001; 24(4):257-63.

2000

Banwell BL, Engel AG. AlphaB-crystallin immunolocalization yields new insights into inclusion body myositis. Neurology. 2000; 54(5):1033-41.

1999

Banwell BL, Russel J, Fukudome T, Shen XM, Stilling G, Engel AG. Myopathy, myasthenic syndrome, and epidermolysis bullosa simplex due to plectin deficiency. Journal of neuropathology and experimental neurology. 1999; 58(8):832-46.

Banwell BL, Becker LE, Jay V, Taylor GP, Vajsar J. Cardiac manifestations of congenital fiber-type disproportion myopathy. Journal of child neurology. 1999; 14(2):83-7.

1994

Banwell BL, Singh NC, Ramsay DA. Prolonged survival in neonatal nemaline rod myopathy. Pediatric neurology. 1994; 10(4):335-7.

Books

Schiffmann R, Banwell B: Brain MRI and motor function in leukodystrophies. Neurology Jul 2016.

Chapters

2017

Makhani, N., Brenton, JN., Banwell, B.: Acquired disorders affecting white matter. Pediatric Neurology: Principles and Practice, 6th Edition. Elsevier, 2017.

2016

Narula S, Hopkins SE, Hacohen Y, Banwell B: Acute disseminated encephalomyelitis. International Neurology 2nd Edition. R. P. Lisak, D. D. Truong, W. M. Carroll and R. Bhidayasiri (eds.). Wiley-Blackwell, Jun 2016.

Hopkins, S, Hacohen, Y, Narula, S, Banwell, B: Multiple Sclerosis in Children. International Neurology 2nd Edition. R. P. Lisak, D. D. Truong, W. M. Carroll and R. Bhidayasiri (eds.). Wiley-Blackwell, Page: 361-364, Jun 2016.

2015

Sona N, Yeshokumar A, Banwell B: Central Nervous System Vasculitis. Nelson Pediatrics 21st Edition Apr 2015 Notes: (revisions to prior chapter: Heather A. Van Mater, William B. Gallentine and Susanne M. Benseler).

Aubert-Broche, B, Fonow, V, Weier, K, Narayanan, S, Arnold, D, Banwell, B, Collins, L: Is it Possible to Differentiate the Impact of Pediatric Monophasic Demyelinating Disorders and Multiple Sclerosis After a First Episode of Demyelination. Spatio-temporal Image Analysis for Longitudinal and Time-Series Image Data. Springer, Page: 38-48, January 2015.

2013

Banwell B, Buncic R: Optic neuritis in children. In: Inflammatory and autoimmune disorders of the nervous system in children. Dale RC, Vincent A (eds.). Mac Keith Press, London, UK, 2013.

2012

Stone R, Banwell B: Pediatric Multiple Sclerosis. In: Multiple Sclerosis and CNS Neuroimmunologic Disorders. Samkoff L, Goodman A (eds.). Wiley-Blackwell, West Sussex, England, 2012.

Makhani N, Banwell B: Acquired disorders affecting white matter. In: Principles and Practice, 5th Edition. Swaiman, Ashwal, Ferriero (eds.). Mosby, Page: pp 1052-1061, 2012.

2009

Vekateswaran S, Banwell B: Pediatric multiple Sclerosis. In: Multiple Sclerosis 3-Blue Books of Neurology. Luccinetti CF, Hohlfeld R (eds.). Elsevier, Philadelphia, PA, Page: pp 185-205, 2009.

Banwell B: Acute disseminated encephalomyelitis. In: International Neurology: A clinical Approach. Lisak RP, Truong DD, Carroll WM, Bhidayasiri R (eds.). Wiley-Blackwell Publishing, Harrisonburg, VA, Page: pp 381-388, 2009.

Banwell B: Acquired Demyelination of the Central Nervous System. In: Current Management of Child Neurology, 4th Edition. Maria BL (eds.). BC Decker Inc, Hamilton, London, Page: pp 580-888, 2009.

2008

Banwell B: Pediatric multiple sclerosis. In: Multiple sclerosis: A comprehensive text. Raine CS, McFarland HF, Hohfeld R (eds.). Elsevier, Philadelphia, Page: pp 43-54, 2008.

2006

Banwell BL: Muscular dystrophies. In: Neurological Therapeutics: Principles and Practice, 2nd Edition. Noseworthy (eds.). Martin Dunitz Ltd, London, Page: pp 2619-36, 2006.

Banwell BL: Principles of muscle disorders. In: Neurological Therapeutics: Principles and Practice, 2nd Edition. Martin Dunitz Ltd (eds.). Noseworthy, London 2006, Page: pp 2601-18, 2006.

2004

Banwell, BL: X-linked vacuolar myopathies. Myology, 3rd edition. Engel, A.G., Franzini-Armstrong, C. (eds.). McGraw-Hill Ltd, New York, Page: 1163-68, 2004.

Banwell, B.L., Gomez, M: The Clinical examination. Myology, 3 edition. Engel, A.G., Franzini-Armstrong, C (eds.). McGraw-Hill Ltd, New York, Page: pp 599-617, 2004.

2003

Banwell BL: Principles of muscle disorders. Neurological Therapeutics: Principles and Practice. Noseworthy (eds.). Martin Dunitz Ltd, London 2003, Page: 2295-00, 2003.

Banwell BL: Muscular dystrophies. Neurological Therapeutics: Principles and Practice. Noseworthy (eds.). Martin Dunitz Ltd., London (C), Page: pp 2312-27, 2003.

2002

Banwell B: Muscular Dystrophy. In: NORD Guide to Rare Disorders. National Organization for Rare Disorders (eds.). Lippincott Williams & Wilkins, Philadelphia, Page: 624, 2002.

Posters and Presentations

2019

Krupp L, Banwell B, Chitnis T, Deiva K, Gärtner J, Ghezzi A, Huppke P, Waubant E, Pearce GL, Stites T, K-Laflamme A, Karan R: Fingolimod Treatment Improved Quality of Life in Paediatric Patients With Multiple Sclerosis: PARADIGMS Study. Presented at the European Paediatric Neurology Society (EPNS) congress; Athens, Greece September 2019 Notes: Platform Presentation.

Waters P, Fadda G, Woodhall M, Irani SR, O'Mahony J, Brown RA, Castro DA, Longoni G, Yeh EA, Marrie RA, Arnold DL, Banwell B, Bar-Or A, on behalf of The Canadian Pediatric Demyelinating Disease Network: Anti-MOG IgG1 Antibodies in Children. Presented by The American Academy of Neurology Annual Meeting; Philadelphia, PA May 2019 Notes: Platform Presentation

Sollee J, Datta R, Minkoff C, Liu G, Cooper H, Vanderver A, Banwell B, Waldman A: White and Gray Matter Brain Volumes in Early-Onset Alexander Disease. Presented at The American Academy of Neurology Annual Meeting; Philadelphia, PA May 2019 Notes: Platform Presentation

Mexhitaj I, Nyirenda M, Li R, O'Mahony J, Rezk A, Rozenberg A, Moore C, Johnson T, Sadovnick D, Collins L, Arnold DL, Gran B, Yeh EA, Marrie RA, Banwell B, Bar-Or A, On behalf of the Canadian Pediatric Demyelinating Disease Network: Assessing the Balance Between Effector and Regulatory T cell Subsets in Pediatric Multiple Sclerosis. Presented at The American Academy of Neurology Annual Meeting; Philadelphia, PA May 2019 Notes: Platform Presentation

Mexhitaj I, Nyirenda M, Li R, O'Mahony J, Rezk A, Rozenberg A, Moore C, Johnson T, Sadovnick D, Collins L, Arnold DL, Gran B, Yeh EA, Marrie RA, Banwell B, Bar-Or A, On behalf of the Canadian Pediatric Demyelinating Disease Network: Abnormal Frequency and Function of MR1-defined MAIT cells in Pediatric Multiple Sclerosis. Presented at The American Academy of Neurology Annual Meeting; Philadelphia, PA May 2019 Notes: Platform Presentation

Longoni G, Brown R, Young K, Berenbaum T, Fetco D, Grover S, Costello F, Reginald AY, Bar-Or A, Marrie RA, Arnold D, Narayanan S, Banwell B, Sled J, Mabbott D, Yeh AE : Magnetization Transfer Saturation Reveals Subclinical Optic Nerve Demyelination in Pediatric Multiple Sclerosis Presented at The American Academy of Neurology Annual Meeting; Philadelphia, PA May 2019 Notes: Poster Presentation.

Gambrah CS, Banwell B, O'Mahony J, Marrie RA: Early Life Nutrition and Risk of Pediatric Multiple Sclerosis Presented at The American Academy of Neurology Annual Meeting; Philadelphia, PA May 2019 Notes: Platform Presentation.

Fadda G, Waters P, Woodhall M, Irani SR, Brown RA, O'Mahony J, Castro DA, Longoni G, Yeh EA, Marrie RA, Arnold DL, Banwell B, Bar-Or A, on behalf of The Canadian Pediatric Demyelinating Disease Network: Prospective characterization of children positive for anti-MOG antibodies meeting Multiple Sclerosis diagnostic criteria. Presented at The American Academy of Neurology Annual Meeting; Philadelphia, PA, May 2019 Notes: Poster Presentation

Dunn C, O'Mahony J, Hanwell H, Yeh EA, Marrie RA, Bar-Or A, Banwell B: Relationship between Skin Pigmentation, HLA, Vitamin D Status and Pediatric-Onset Multiple Sclerosis. Presented at The American Academy of Neurology Annual Meeting; Philadelphia, PA May 2019 Notes: Platform Presentation

Datta R, Till C, DeSomma E, Barlow-Krelina E, Akbar N, Dolui S, Narayanan S, Arnold D, Yeh EA, Banwell B: Loss of intrathalamic tissue integrity in pediatric-onset multiple sclerosis measured with DTI Presented at The American Academy of Neurology Annual Meeting; Philadelphia, PA May 2019 Notes: Poster Presentation.

Brown R, Fadda G, Longoni G, Castro D, O'Mahony J, Bar-Or A, Marrie RA, Yeh EA, Arnold D, Banwell B: Assessment of Baseline Imaging Features as Predictors of Poor Disease Course in Pediatric Onset Multiple Sclerosis. Presented at The American Academy of Neurology Annual Meeting; Philadelphia, PA May 2019 Notes: Platform Presentation

Brenton JN, Banwell B, Bergqvist AGC, Lehner-Gulotta D, Gampper L, Leytham E, Goldman MD: Modified ketogenic diet therapy for relapsing-remitting multiple sclerosis: patient reported outcomes. Presented at The American Academy of Neurology Annual Meeting; Philadelphia, PA May 2019 Notes: Poster Presentation

2018

Waubant E, Banwell B, Wassmer E, Sormani MP, Amato MP, Hintzen R, Krupp L, Rostasy K, Tenembaum S, Chitnis T: Clinical Trials of Disease-Modifying Agents in Pediatric MS: Opportunities, Challenges, and Recommendations from the International Pediatric MS Study Group (IPMSSG). Presented at the European Committee for Treatment and Research in Multiple Sclerosis (ECTRIMS) Annual Meeting, Berlin, Germany Oct 2018 Notes: Poster Presentation.

Wassmer E, Banwell B, Chitnis T, Waubant E, Deiva K: Perspectives on Clinical Trials in Pediatric MS: results of an international survey. Presented at the European Committee for Treatment and Research in Multiple Sclerosis (ECTRIMS) Annual Meeting, Berlin, Germany Oct 2018 Notes: Poster Presentation.

Krupp L, Banwell B, Chitnis T, Deiva K, Gartner J, Ghezzi A, Huppke P, Waubant E, Pearce GL, Stites T, Merschhemke M: Effect of fingolimod on quality of life in paediatric MS: Results of the Phase 3 PARADIGMS Study. Presented at the European Committee for Treatment and Research in Multiple Sclerosis (ECTRIMS) Annual Meeting, Berlin, Germany Oct 2018 Notes: Poster Presentation.

Hopkins S, Khambhampati A, Vossough A, Banwell, B: Acute Flaccid Myelitis at the Children's Hospital of Philadelphia: Baseline Occurrence and Recent Clusters. Presented at the Child Neurology Society Annual Meeting, Chicago, Illinois Oct 2018.

Grover SA, Berenbaum T, Nandamalavan D, Yea C, Iruthayanathan R, Wilbur C, Albassam F, Longoni G, Reginald A, Wan M, Costello F, O'Mahony J, Arnold D, Banwell B, Bar-Or A, Marrie RA, Mabbott D: Retinal Nerve Fiber Layer and Ganglion Cell Inner Plexiform Layer in Youth with Serum Myelin Oligodendrocyte Glycoprotein Antibody Positivity. Presented at the European Committee for Treatment and Research in Multiple Sclerosis (ECTRIMS) Annual Meeting, Berlin, Germany Poster Presentation, Oct 2018.

Fadda G, Water P, Woodhall M, Irani SR, Brown RA, O'Mahony J, Castro D, Longoni G, Yeh EA, Marrie RA, Arnold DL, Banwell B, Bar-Or A: Prospective clinical and MRI characterization of children with serum anti-MOG antibodies meeting the multiple sclerosis diagnostic criteria. Presented at the European Committee for Treatment and Research in Multiple Sclerosis (ECTRIMS) Annual Meeting, Berlin, Germany Oct 2018 Notes: Poster Presentation.

Fabri, TL, Datta, R, O'Mahony, J, Bar-Or, A, Yeh, EA, Arnold, DL, Marrie, RA, Banwell, BL, Till C: Memory and Identification of Emotional Expression in Pediatric-Onset MS. Presented at The International Multiple Sclerosis Cognition Society (IMSCOGS) Annual Meeting, Berlin, Germany Oct 2018 Notes: Poster Presentation.

Fabri TL, Datta R, O'Mahony J,Gur RE, Gur RC, Bar-Or A, Yeh EA, Arnold, DL, Marrie, RA, Banwell BL, Till, C: Memory and Identification of Emotional Expression in Pediatric-Onset MS Presented at the European Committee for Treatment and Research in Multiple Sclerosis (ECTRIMS) Annual Meeting, Berlin, Germany Oct 2018 Notes: Poster Presentation.

Dunn, C, Hanwell, H, Ebrahimi, N, Banwell B, Bar-Or, A, Marrie, RA, Yeh EH, Yea C, O'Mahony, J: The Relationship Between Skin Pigmentation, HLA, Vitamin D Status and Pediatric-Onset Multiple Sclerosis. Presented at the European Committee for Treatment and Research in Multiple Sclerosis (ECTRIMS) Annual Meeting, Berlin, Germany Oct 2018 Notes: Poster Presentation.

Datta, R, Till, C, DeSomma, E, Barlow-Krelina, E, Akbar, N, Narayanan, S, Arnold, D, Yeh, EA, Banwell, BL: DTI alterations in the thalamic connectivity-based regions in pediatric-onset Multiple Sclerosis. Presented at the European Committee for Treatment and Research in Multiple Sclerosis (ECTRIMS) Annual Meeting, Berlin, Germany Oct 2018 Notes: Poster Presentation.

Datta, R, Sollee, J, Lavery, A, Dolui, S, Karoscik, K, Liu, G, Banwell, BL, Waldman, AT: Alterations along the posterior visual pathway in pediatric-onset multiple sclerosis. Presented at the European Committee for Treatment and Research in Multiple Sclerosis (ECTRIMS) Annual Meeting, Berlin, Germany Oct 2018 Notes: Poster Presentation.

Brenton JN, Banwell B, Bergqvist AGC, Lehner-Gulotta D,Leytham E, Goldman MD: Application of a modified ketogenic diet in relapsing-remitting multiple sclerosis subjects: a pilot study. Presented at the European Committee for Treatment and Research in Multiple Sclerosis (ECTRIMS) Annual Meeting, Berlin, Germany Oct 2018.

Waldman AT, Datta R, Sollee J, Lavery AM, Liu GW, Aleman T, Banwell BL, Gaetz W: Cortical oscillations in pediatric-onset multiple sclerosis: atypical visual gamma-band response and reduced post-movement beta rebound. Presented at the International Conference on Biomagnetism, Philadelphia, PA Aug 2018.

Perason, A, Grover, S, Nandamalavan D, Berenbaum T, Motl RW, Finlayson M, Banwell B, Yeh EA: Moderate-to-Vigorous Physical Activity is Positively Associated with the Retinal Nerve Fibre Layer Thickness in Pediatric Multiple Sclerosis. Presented at the Consortium of Multiple Sclerosis Centers (CMSC) Annual Meeting, Nashville, Tennessee May 2018 Notes: Poster Presentation.

O'Mahony J, Marrie RA, Bar-Or A, Yeh EA, Banwell, B: Pediatric-Onset Multiple Sclerosis is Associated with Reduced Parental Health-Related Quality of Life and Family Functioning. Presented at the Consortium of Multiple Sclerosis Centers (CMSC) Annual Meeting, Nashville, Tennessee May 2018 Notes: Platform Presentation.

Dunn, CL, Yea, C, Hanwell, HE, Yeh EA, Marrie, RA, Bar-Or A, Ebrahimi N, Banwell, B, O'Mahony J: Relationship Between Skin Tone and Pediatric-Onset Multiple Sclerosis (MS). Presented at the Consortium of Multiple Sclerosis Centers (CMSC) Annual Meeting, Nashville, Tennessee May 2018 Notes: Poster Presentation.

Banwell, B, Arnold, D, Bar-Or A, Ghezzi A, Greenberg B, Waubant E, Giovannoni G, London D, Wolinsky JS, Gaertner J, Rostasy K, Krupp L, Tardieu M, Brueck W, Stites T, Pearce GL, Merschhemke M, Chitnis T: Effects of Fingolimod on Magnetic Resonance Imaging Outcomes in Patients with Pediatric-Onset Multiple Sclerosis: Results from the Phase 3 Paradigms Study Presented at the Consortium of Multiple Sclerosis Centers (CMSC) Annual Meeting, Nashville, Tennessee May 2018 Notes: Platform Presentation.

Waldman, A, Sollee, J, Lavery, A, Karoscik, K, Liu, G, Shinohara, R, Banwell, BL, Datta, R: The Impact of Occipital Cortical Mantle Thinning on Visual Processing in Pediatric Multiple Sclerosis. Presented at the American Academy of Neurology (AAN) Annual Meeting, Los Angeles, California Apr 2018 Notes: Platform Presentation.

Hopkins SE, Gordon-Lipkin E, VanHaren K, Santoro J, Munoz-Arcos L, Matesanz S, Pardo-Cillamizar C, Banwell B: MRI Brain Abnormalities in Acute Flaccid Myelitis: Characteristics and Differentiation from Acute Disseminated Encephalomyelitis. Presented at the American Academy of Neurology Annual Meeting, Los Angeles, California Apr 2018 Notes: Poster Presentation.

Fadda G, Brown RA, Longoni G, Castro DA, O'Mahony J, Verhey LH, Branson HM, Waters P, Bar-Or A, Marrie RA, Yeh EA, Narayanan S, Arnold DL, Banwell B, on behalf of the Canadian Pediatric Demyelinating Disease Network: MRI Contributions to the Diagnosis of Multiple Sclerosis in Children. Presented at the American Academy of Neurology (AAN) Annual Meeting, Los Angeles, California Apr 2018 Notes: Platform Presentation.

Neufeld R, Fabri T, Sergio L, Waldman A, Lavery A, Gorbet D, Till C: The Effect of Cognitive Load on Visuomotor Integration in Youth with Multiple Sclerosis. Presented at the International Neuropsychological Society Annual Meeting, Washington, DC Feb 2018 Notes: Poster Presentation.

De Somma E, Brow RA, Sadeghi M, O'Mahoney J, Brooks BL, Yeh EA, Arnold D, Collins DL, Aubert-Broche B, Narayanan S, Marrie RA, Bar-Or A, Banwell B, Till C, on behalf of the Canadian Pediatric Demyelinating Disease Study: Disrupted cognitive development following acute demyelinating syndromes: A longitudinal study. Presented at the International Neuropsychological Society Annual Meeting, Washington, DC Feb 2018 Notes: Poster Presentation.

Barlow-Krelina, E, Yeh, EA, O'Mahony, J, Banwell, B, Till, C, on behalf of the Canadian Pediatric Demyelinating Disease Study: Examining executive dysfunction as a contributor to verbal reasoning deficits in young adults with pediatric-onset multiple sclerosis. Presented at the International Neuropsychological Society Annual Meeting, Washington, DC Feb 2018 Notes: Poster Presentation.

2017

Tanuja Chitnis, Douglas Arnold, Brenda Banwell, Wolfgang Bruck, Angelo Ghezzi, Gavin Giovannoni, Benjamin Greenberg, Lauren Krupp, Kevin Rostasy, Marc Tardieu, Emmanuelle Waubant, Jerry Wolinsky, Amit Bar-Or, Tracy Stites, Nicola Jessop, Yu Chen, martin B. Merschhemke, Jutta Gartner: Baseline Characteristics of Pediatric Patients With Multiple Sclerosis Enrolled in the PARADIGMS Study: A Randomized Double-blind Study of Fingolimod Versus Interferon. Presented at the PARADIGMS American Academy of Annual Meeting 2017 Notes: Poster Presentation.

Prelack, M, Datta, R, Brown, R, Radcliffe, A, Taub, K, Capal, J, Krueger, D, Banwell, B: White Matter Maturation in Children with Tuberous Sclerosis Complex on Everolimus Therapy. Presented at the American Epilepsy Society Annual Meeting, Washington DC Dec 2017 Notes: Poster Presentation.

Fadda G, Nyirenda M, Mexhitag I, Healy L, Poliquin-Lasnier L, Hanwell H, Saveriano A, Rozenberg A, Li R, Moore CS, Belabani C, Johnson T, O'Mahony J, Marrie RA, Dunn S, Banwell B, Bar-Or A, on behalf of the Canadian Pediatric Demyelinating Disease Network: Elevated adiponectin levels induce pro-inflammatory myeloid- and T-cell responses linking adiposity and predisposition to pediatric MS. Presented at the Joint European Committee for Treatment and Research in Multiple Sclerosis (ECTRIMS) and American Committee for Treatment and Research in Multiple Sclerosis (ACTRIMS) Annual Meeting, Paris, France Oct 2017 Notes: Top Scored Poster Presentation.

Fadda G, Brown RA, Madliozzi B, Aubert-Broche A, O'Mahony J, Banwell B, Collins DL, Arnold DL, Bar-Or A, on behalf of the Canadian Pediatric Demyelinating Disease Network: Serial MRI detects presence and evolution of a 'surface-in' gradient of thalamic damage in paediatric-onset MS, which is recapitulated in adult MS autopsy. Presented at the Joint European Committee for Treatment and Research in Multiple Sclerosis (ECTRIMS) and American Committee for Treatment and Research in Multiple Sclerosis (ACTRIMS) Annual Meeting, Paris, France Oct 2017 Notes: Platform Presentation; Selected for Conference's Clinical Highlights.

De Somma E, Akbar N, Datta, R, Yeh EA, Banwell B, Till C: Physical Activity and its Association with White Matter Integrity and Cognitive Efficiency in Pediatric-Onset Multiple Sclerosis. Presented at the European Committee for Treatment and Research in Multiple Sclerosis (ECTRIMS) Annual Meeting, Paris, France Oct 2017 Notes: Poster Presentation.

Datta R, Sollee J, Lavery A, Karoscik K, Ficerai-Garland G, Banwell B, Waldman A: Cortical Mantle Thinning in the Visual Cortex in Pediatric-Onset Multiple Sclerosis. Presented at the European Committee for Treatment and Research in Multiple Sclerosis (ECTRIMS) Annual Meeting, Paris, France Oct 2017 Notes: Poster Presentation.

Barlow-Krelina E, De Somma E, Yeh EA, O'Mahony J, Gur RE, Gur KR, Banwell B, Till C: Deficits above and beyond slowed processing speed. Presented at the European Committee for Treatment and Research in Multiple Sclerosis (ECTRIMS) Annual Meeting, Paris, France Oct 2017 Notes: Poster Presentation; Received a Travel Award.

Green R, Adler A, Collins DL, Banwell B, Till C: Involvement of the amygdala in memory and social functioning in pediatric-onset multiple sclerosis. Presented at the International MS Cognition Society (IMSCOGS) Annual Meeting, Dusseldorf, Germany Jun 2017 Notes: Platform Presentation.

Hopkins S, Mcguire J, Swami S,Ulloa ER, Banwell B: Acute Flaccid Myelitis: Characteristics and Outcomes in 2014 and 2016 Clusters. Presented at the American Academy of Neurology (AAN) Annual Meeting, Boston, Massachusetts April 2017 Notes: Platform Presentation.

Fadda G, Brown RA, Aubert-Broche B, Banwell B, Collins DL, Arnold DL, Bar-Or A, on behalf of the Canadian Pediatric Demyelinating Disease Network: A 'surface-in' gradient of thalamic damage is an early and disease specific process in paediatric-onset MS. Presented at the American Academy of Neurology (AAN) Annual Meeting, Boston, Massachusetts Apr 2017 Notes: Emerging Science Session Platform Presentation

Datta, R, Sophia LS, Till, C, De Somma, E, Akbar, N, Dolui, S, Arnold, DL Narayanan, S, Banwell, BL: DTI abnormalities in the midbrain in pediatric-onset multiple sclerosis. Presented at the International Society for Magnetic Resonance in Medicine (ISMRM) Annual Meeting, Honolulu, Hawaii Apr 2017 Notes: Platform Presentation.

Invited Lectures

2019

Banwell BL. Current Concepts in Paediatric MS, Virtual Conference, "Clinical trials in Paediatric MS should be conducted for study drugs with established efficacy in adult MS", Expert Panelist, Treatment and Research in Multiple Sclerosis Online. Jun 2019.

Banwell BL. "Demyelinating Neurologic Emergencies", Chilean Pediatric Neurocritical Care Conference", Santiago, Chile. Jun 2019.

Banwell BL. "How does Paediatric-onset MS Differ to Adult-onset Disease: Will the PARADIGMS Trial Results Change the Way We Treat Paediatric-onset MS?, Digital Table Meeting, The Corpus, Philadelphia, PA. Jun 2019.

Banwell BL. "Neuromuscular Neurologic Emergencies", Chilean Pediatric Neurocritical Care Conference, Santiago, Chile. Jun 2019.

Banwell BL. "Demyelinating Neurologic Emergencies", Chilean Pediatric Neurocritical Care Conference", Santiago, Chile. Jun 2019.

Banwell BL. "Multiple Sclerosis": Management", Chilean Pediatric Neurocritical Care Conference, Santiago, Chile. Jun 2019.

Banwell BL. "Multiple Sclerosis", American Academy of Neurology Brain Health Fair, Philadelphia, PA. May 2019.

Banwell BL. "Diagnostic Pearls in Myelitis: a Case-based Approach", American Academy of Neurology, Philadelphia, PA. May 2019.

Banwell BL. "Biological and MRI Evidence in Pediatric Multiple Sclerosis: is it different from MS in adults?" Recording, The Corpus, Philadelphia, PA. Apr 2019.

Banwell BL. "Pediatric MOG Antibody-Associated Disease and ADEM", Transverse Myelitis Association's, Ask The Expert Podcast Series, Philadelphia, PA. Mar 2019.

Banwell BL. Women in Neurology Round Table Discussion, 2019 AAN Neurology Chair Summit, Chicago, IL. Mar 2019.

Banwell BL. "New Drugs for Pediatric MS - clinical studies and current status, Warsaw, Poland, Mar 2019.

Banwell BL. "New drugs for Pediatric MS - clinical studies and current status", Conference Multiple Sclerosis in Children and Young Adults, Congress Office SKOLAMED, Warsaw, Poland. Mar 2019.

Banwell BL. "MRI Features of MS in Children: insights from the youngest patients", Neurology Grand Rounds, Montreal Neurological Institute, Montreal, Quebec. Feb 2019.

Banwell BL. "MS in Children - Journey of a Clinical Investigator", Montreal Neurological Institute Seminar Series, Montreal Neurological Institute, Montreal, Quebec. Feb 2019.

Banwell BL. "The Impact of Multiple Sclerosis on Cognition and Cognitive Maturation in Children", Cognition and Circuits Seminar Series:, Montreal Neurological Institute, Montreal, Quebec. Feb 2019.

Banwell BL. "Biological and MRI Evidence in Pediatric Multiple Sclerosis: is it different from MS in Adults?", Virtual Global, The Corpus. Jan 2019.

Banwell BL. "Biological and MRI Evidence in Pediatric Multiple Sclerosis: is it different from MS in adults? - The Corpus, Virtual, Global Audience, Philadelphia, PA. Jan 2019.

2018

Banwell BL. "Workshop: Guidelines for the assessment of lesions in multiple sclerosis", BioMedia, Milan, Italy. Dec 2018.

Banwell BL. "A Review of the Clinical Features and Management of Multiple Sclerosis in Children", Fourth MENACTRIMS Congress 2018, Dubai. Nov 2018.

Banwell BL. "Pediatric Manifestation of Multiple Sclerosis", Multiple Sclerosis: akute Manifestationen", Annual Meeting German Neuropediatric Society. Nov 2018.

Banwell BL. "Pediatric MS: Diagnosis and Treatment", Approaches to Management in MS, Fourth MENACTRIMS Congress 2018, Dubai. Nov 2018.

Banwell BL. "How does Paediatric-onset differ to adult-onset disease?", Virtual presentation, The Corpus, presenting to Spain. Oct 2018.

Banwell BL. MRI in Pediatric MS, European Committee for Treatment and Research in Multiple Sclerosis (ECTRIMS) Annual Meeting, Berlin, Germany. Oct 2018.

Banwell BL. Paediatric MS: Treatment in the era, European Committee for Treatment and Research in Multiple Sclerosis (ECTRIMS) Annual Meeting, Berlin, Germany. Oct 2018.

Banwell BL. Acting early: new evidence in the treatment of Paediatric-onset MS, European Committee for Treatment and Research in Multiple Sclerosis (ECTRIMS) Annual Meeting, Berlin, Germany. Oct 2018.

Banwell BL. "Biological and MRI Evidence in Pediatric Multiple Sclerosis: Is it different from MS in adults?, Virtual, The Corpus, Philadelphia, PA. Sept 2018.

Banwell BL. 2018 Annual Meeting of the Consortium of Multiple Sclerosis Centers, Pediatric MS Course, Nashville, Tennessee. Aug 2018.

Banwell BL. "Imaging Pediatric MS", Magnetic Resonance Techniques in Multiple Sclerosis, Twenty-first Advanced Course, Milan, Italy. May 2018.

Banwell BL. "Imaging Pediatric MS", BioMedia La condivisione del sapere, Milan. May 2018.

Banwell BL. "MRI Insights Into Pediatric Multiple Sclerosis", Columbia University Medical Center, Neurology Grand Rounds, New York, NY. Apr 2018.

Banwell BL. "Effects of Fingolimod on MRI Outcomes in Patients with Pediatric Onset Multiple Sclerosis: Results from Phase 3 PARADIGMS Study", 2018 American Academy of Neurology, 2018 Annual Meeting, Los Angeles. Apr 2018.

Banwell BL. "Journey of a Clinical Investigator: Building a Pediatric Multiple Sclerosis Program", Grand Rounds, The University of Kansas Medical Center, 2018 2nd Annual Lillian Gonzales-Pardo, MD Pediatric Neurology Lectureship, Kansas. Mar 2018.

Banwell BL. "Neuroimaging Insights into Pediatric Multiple Sclerosis", Temple University School of Medicine, Philadelphia, PA. Jan 2018.

2017

Banwell BL. Grand Rounds, "Pediatric Multiple Sclerosis: Lessons learned from the youngest patients", Memorial Healthcare System, Memorial Neuroscience Institute, Memorial Regional Hospital, Hollywood Florida. Dec 2017.

Banwell BL. "Biological and MRI Evidence in Pediatric Multiple Sclerosis: is it different from MS in adults?", The Corpus, Audience Location Global (Turkey, Argentina, Hungary, Sweden Georgia). Dec 2017.

Banwell BL. "Biological and MRI Evidence in Pediatric Multiple Sclerosis: is it different from MS in adults?", Virtual, The Corpus, London, UK. Dec 2017.

Banwell BL. Symposium Speaker, "Paediatric Multiple Sclerosis: Lessons children teach us" 33rd Annual J. Allyn Taylor International Prize in Medicine Symposium: Discovery and Innovation in Multiple Sclerosis, Roberts Research Institute, Schulich School of medicine & Dentistry, Western University, London, ON, Canada. Nov 2017.

Banwell BL. Neuroscience Rounds, "Visualizing Multiple Sclerosis: insights gained by neuroimaging studies in children", Max Rady College of Medicine, Rady Faculty of Health Sciences, University of Manitoba, Winnipeg, MB. Nov 2017.

Banwell BL. "Acute Disseminated Encephalomyelitis", 2017 Rare Neuro-Immune Disorders Symposium, Columbus, OH. Oct 2017.

Banwell BL. "What Are Rare Neuro-Immune Disorders?, 2017 Rare Neuro-Immune Disorders Symposium, The Transverse Myelitis Association, Columbus, OH. Oct 2017.

Banwell BL. Corpus Digital Table Meeting - Biological and MRI Evidence in Pediatric Multiple Sclerosis: is it different from MS in Adults?, Merck Global Medical Education, Philadelphia, PA. Sep 2017.

Banwell BL. Biological and MRI Evidence in Pediatric Multiple Sclerosis: Is it different from MS in adults?, Virtual, The Corpus, Philadelphia, PA. Sep 2017.

Banwell BL. Wed-series - "EXCEMED MS Talks, Pediatric MS", Invited Speaker - Paris, France. May 2017.

Banwell BL. "The Role of Neuroimaging in Pediatric Multiple Sclerosis", Baldwin Lecture at the University of Maryland (Grand Rounds), University of Maryland, Department of Neurology, Baltimore, MD. Apr 2017.

Banwell BL. "MS TeamWorks", The Consortium of Multiple Sclerosis Centers, International Organization for Multiple Sclerosis Nurses (IOMSN), Catamount Medical Education and Nurse Practitioner Alternatives, Washington, DC. Apr 2017.

Banwell BL. "Neuroscience in Clinic: Neurologic Disorder Through a Lifespan - A Focus on MS", American Academy of Neurology, Boston, Massachusetts. Apr 2017.

Banwell BL. Management of Cognitive Impairment in Pediatric MS Patients, American Academy of Neurology (AAN) Annual Meeting, Boston, Massachusetts. Apr 2017.

Banwell BL. "Pediatric Multiple Sclerosis", Novartis Grand Rounds - Webex, Invited Speaker, Novartis Pharmaceuticals Corporation, Philadelphia, PA. Mar 2017.

Banwell BL. "Biological and MRI Evidence of "Early" Multiple Sclerosis: lessons learned from pediatric patients", Grand Rounds, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts. Mar 2017.

Banwell BL. "MRI Features of Multiple Sclerosis in Children: a window into the earliest aspects of MS Biology", Lurie Children's Hospital/Northwestern Memorial Hospital Grand Rounds, Chicago, Illinois. Feb 2017.

Banwell BL. "Neuroimaging Insights in Pediatric MS", Boston Children's Hospital/Harvard Medical School Grand Rounds, Boston, Massachusetts. Feb 2017.

Banwell BL. "Demyelinating disease in the Pediatric Population", Breakthroughs in Neurology Conference: Translating Today's Discoveries into Tomorrow's Clinic, American Academy of Neurology, Phoenix, Arizona. Jan 2017.

Awards and Honors

2019, Guest of Honor, Chaim Medical Resource Organization
2018, 2nd Annual Lillian Pardo, MD, Lectureship Award, Pediatric Neurology Professorship Lecture, Department of Neurology, University of Kansas Medical Center
2018, 2022, Philadelphia Magazine's Top Doctors in Child Neurology
2017, Special Recognition, Baldwin Lecture in Pediatrics Neurology, University of Maryland, School of Medicine, Department of Neurology
2016, The Lady Barbara Colyton Prize for Autoimmune Research, Perelman School of Medicine, University of Pennsylvania
2015, Sidney Carter Award, American Academy of Neurology and The American Brain Foundation
2014, "Women on the Move", Mainline Today
2012, The William A. Hawke Award-Clinical Excellence in Teaching, The Hospital for Sick Children
2012, The CANMEDS Award for Clinical Excellence, Division of Neurology, The Hospital for Sick Children
2008, Robert Salter Humanitarian Award Nominee-The Hospital for Sick Children
2007, Woman Against Multiple Sclerosis-Woman of the Year Award
2006, Canada's Top 40 Under 40 Recipient
2006, AAN Leadership Development Program (Selected), American Academy of Neurology
2002, 2004, 2006, The William A. Hawke Award-Clinical Excellence in Teaching, The Hospital for Sick Children
2002, Faculty Award for Clinical Excellence, The Hospital for Sick Children
2000, The Department of Neurology Research Award, Mayo Clinic-(awarded by the Mayo Clinic Foundation)
1997, The President's Prize, Canadian Congress of Neurological Sciences
1997, American Academy of Neurology Resident Scholarship Award
1997, Humanitarian Award, The Hospital for Sick Children Foundation
1996, The Pritchard Prize, Annual Neurology Resident Research Day, Department of Pediatric Neurology, University of Toronto
1994, The Neurosciences Research Award, Neuroscience Research Day, Department of Neurology, University of Western Ontario
1994, The Resident Teaching Award, University of Western Ontario
1993, The Wyeth Award for Pediatric Research, Sixth Annual Resident Research Day, Department of Pediatrics, University of Western Ontario.
1991, The Hewlett-Packard Top Medical Graduate Award, University of Western Ontario
1991, The Dr. Henri Breault Award, University of Western Ontario
1990, The Martin and Mary Leboldus Award, University of Western Ontario
1989, M.D.S. Health Group Prize in Pathology
1989, Bronze W Award-Varsity Swimming
1989-1991, Alpha Omega Alpha Honour Society
1988, The Rix Family Prize in Pathology
1988, The London Academy of Medicine Entrance Scholarship
1987-1991, Dean's Honour Roll, Medicine
1986, National Science and Research Council Award
1985-1989, The Trois Pistoles 50th Anniversary Scholarship, University of Western Ontario Entrance Scholarship

Editorial and Academic Positions

Editorial Positions

  • 2010-present, Invited Manuscript Reviews: Lancet Neurology
  • 2009-present, Invited Manuscript Reviews: Journal of the Neurological Sciences
  • 2006-present, Editorial Board: Multiple Sclerosis
  • 2006-present, Invited Individual Grant Reviews: CIHR
  • 2005-present, Invited Manuscript Reviews: Medical Science Monitor International Reviewer Panel
  • 2004-present, Invited Manuscript Reviews: The Canadian Journal of Neurological Sciences
  • 2004-present, Invited Manuscript Reviews: Journal of Rheumatology
  • 2004-present, Invited Manuscript Reviews: Arthritis Care and Research
  • 2004-present, Invited Individual Grant Reviews: Multiple Sclerosis Society of Canada Research Grant Committee
  • 2004-present, Invited Manuscript Reviews: The Canadian Journal of Neurological Sciences
  • 2004-present, Invited Manuscript Reviews: Journal of the American Medical Association
  • 2004-present, Invited Individual Grant Reviews: Physician Services Incorporated
  • 2004-present, Invited Individual Grant Reviews: Alberta Children's Hospital Foundation
  • 2002-present, Invited Manuscript Reviews: Multiple Sclerosis
  • 2002-present, Invited Manuscript Reviews: Pediatric Research
  • 2002-present, Invited Manuscript Reviews: Pediatrics and Child Health
  • 2001-present, Invited Manuscript Reviews: Journal of Neurology
  • 2000-present, Editorial Board Member and Invited Manuscript Reviewer: Neurology

Academic and Institutional Committees

  • CHOP Clinical Trials Research Affinity Group, Advisory committee member

Leadership and Memberships

Memberships in Professional Organizations

International
  • 2017-present, The Lancet Neurology
    • 2017-present, The Lancet Child & Adolescent Health - International Advisory Board Member
  • 2010-present, Multiple International Federation
    • 2010-present, McDonald Diagnostic Criteria, Invited Member
  • 2007-present, International Pediatric Multiple Sclerosis Study Group
    • 2019-present, Chair
    • 2007-present, Steering Committee
  • 2007-present, International Child Neurology Society
  • 2005-present, Canadian Multiple Sclerosis Society
    • 2010-present, Medical Advisory Committee
    • 2008-present, endMS Campaign Steering Committee
  • 2005-present, Canadian Association of Child Neurology
  • 2004-present, Myositis Support Group UK
    • 2004-present, International Juvenile Dermatomyositis Biopsy Consensus Group, Invited Member
  • 2000-present, 10th International Congress of Neuromuscular Diseases
    • 2000-present, Young Investigator Advisory Board, Appointed Member
  • 1999-present, Consortium of Multiple Sclerosis Centers
National
  • 2017-present, Americas Committee for Treatment & Research in MS
    • 2017-present, Board Member
  • 2017-present, American Brain Foundation
    • 2017-present, Board Member, Expert Review Panel for Autism & Neurodevelopment
  • 2015-present, Society for Pediatric Research
  • 2015-present, Consortium of Multiple Sclerosis Centers
  • 2013-present, American Neurological Association, fellow
  • 2010-present, National Institute of Neurological Disorders and Stroke, National Institutes of Health
    • 2010-present, Common Data Element Task Force, Multiple Sclerosis Database Working Group
  • 2005-present, American Academy of Neurology
    • 2015-present, Fellow
    • 2011-present, Meeting Management Committee
    • 2007-present, Leadership Program Development Committee
  • 1997-present, American Academy of Neurology
    • 2017-2020, Director, Board of Directors
    • 1997-present, Board of Directors
  • 1995-present, American Academy of Pediatrics