Inflammatory Bowel Disease Publications and Presentations

Breton J, Tanes C, Tu V, Albenberg L, Rowley S, Devas N, Hwang R, Kachelries K, Wu GD, Baldassano RN, Bittinger K, Mattei P. A Microbial Signature for Paediatric Perianal Crohn's Disease. J Crohns Colitis. 2022 Aug 30;16(8):1281-1292. doi: 10.1093/ecco-jcc/jjac032.

Zong W, Patel A, Chang V, Mitchel EB, Stoner N, Baldassano RN, Albenberg L. Clinical and lifestyle patterns in Asian children with inflammatory bowel disease in the U.S. PLoS One. 2023 Mar 22;18(3):e0281949. doi: 10.1371/journal.pone.0281949. PMID: 36947496; PMCID: PMC10032481.

Constant BD, Albenberg L, Mitchel EB, de Zoeten EF, Clapp JT, Scott FI; Prior Authorization Impact Network Study Group. Prior Authorizations Delay Therapy, Impact Decision Making, and Lead to Adverse Events in IBD: 2022 Provider Survey. Clin Gastroenterol Hepatol. 2023 Jun 30:S1542-3565(23)00506-2. doi: 10.1016/j.cgh.2023.06.021. Epub ahead of print. PMID: 37394025.

Stein R, Daniel SG, Baldassano RN, Feigenbaum K, Kachelries K, Sigall-Boneh R, Weston S, Levine A, Bittinger K. Outcomes and Predictors of Sustained Remission After Drug Withdrawal in Pediatric Crohn Disease. J Pediatr Gastroenterol Nutr. 2022 Nov 1;75(5):608-615. doi: 10.1097/MPG.0000000000003589. Epub 2022 Aug 17. PMID: 35976282.

Zhang N, Liu C, Steiner SJ, Colletti RB, Baldassano R, Chen S, Cohen S, Kappelman MD, Saeed S, Conklin LS, Strauss R, Volger S, King E, Lo KH. Using multiple imputation of real-world data to estimate clinical remission in pediatric inflammatory bowel disease. J Comp Eff Res. 2023 Apr;12(4):e220136. doi: 10.57264/cer-2022-0136. Epub 2023 Feb 17. PMID: 36799351.

Harris RA, Bush AH, Eagar TN, Qian J, Greenwood MP, Opekun AR, Baldassano R, Guthery SL, Noe JD, Otley A, Rosh JR, Kugathasan S, Kellermayer R. Exome Sequencing Implicates DGKZ, ESRRA, and GXYLT1 for Modulating Granuloma Formation in Crohn's Disease. J Pediatr Gastroenterol Nutr. 2023 Jun 22. doi: 10.1097/MPG.0000000000003873. Epub ahead of print. PMID: 37347142.

Akhlaghpour M, Haritunians T, More SK, Thomas LS, Stamps DT, Dube S, Li D, Yang S, Landers CJ, Mengesha E, Hamade H, Murali R, Potdar AA, Wolf AJ, Botwin GJ, Khrom M; International IBD Genetics Consortium; Ananthakrishnan AN, Faubion WA, Jabri B, Lira SA, Newberry RD, Sandler RS, Sartor RB, Xavier RJ, Brant SR, Cho JH, Duerr RH, Lazarev MG, Rioux JD, Schumm LP, Silverberg MS, Zaghiyan K, Fleshner P, Melmed GY, Vasiliauskas EA, Ha C, Rabizadeh S, Syal G, Bonthala NN, Ziring DA, Targan SR, Long MD, McGovern DPB, Michelsen KS. Genetic coding variant in complement factor B (CFB) is associated with increased risk for perianal Crohn's disease and leads to impaired CFB cleavage and phagocytosis. Gut. 2023 Apr 20:gutjnl-2023-329689. doi: 10.1136/gutjnl-2023-329689. Epub ahead of print. PMID: 37080587.

Kelsen J, Dawany N, Conrad M, Patel T, Devoto M, Maurer K, Sullivan KE. Clinical and laboratory predictors of monogenic very early onset inflammatory bowel disease. Clin Immunol. 2022 Jul;240:109047. doi: 10.1016/j.clim.2022.109047. Epub 2022 May 22. PMID: 35613698.

Shaul E, Conrad MA, Dawany N, Patel T, Canavan MC, Baccarella A, Weinbrom S, Aleynick D, Sullivan KE, Kelsen JR. Canakinumab for the treatment of autoinflammatory very early onset- inflammatory bowel disease. Front Immunol. 2022 Sep 20;13:972114. doi: 10.3389/fimmu.2022.972114. PMID: 36203564; PMCID: PMC9531243.

Wilkins BJ, Kelsen JR, Conrad MA. Reply to: A Pattern-based Approach and Multidisciplinary Discussion Are Fundamental for Diagnosis in Very Early Onset Inflammatory Bowel Disease (VEO-IBD). Adv Anat Pathol. 2022 Jul 1;29(4):260-261. doi: 10.1097/PAP.0000000000000344. Epub 2022 Apr 8. PMID: 35389895; PMCID: PMC9182884.

Ihekweazu FD, Grossman AB. Revisiting Methotrexate Therapy for Pediatric Crohn Disease. J Pediatr Gastroenterol Nutr. 2022 Sep 1;75(3):229-230. doi: 10.1097/MPG.0000000000003544. Epub 2022 Jun 23. PMID: 35984455.

Kastl AJ, Weaver KN, Zhang X, Strople JA, Adler J, Dubinsky MC, Bousvaros A, Watkins R, Dai X, Chen W, Cross RK, Higgins PDR, Ungaro RC, Bewtra M, Bellaguarda EA, Farraye FA, Chun KY, Zikry M, Fernando M, Bastidas M, Hernandez CG, Craig RG, Boccieri ME, Firestine A, Long MD, Kappelman MD. Humoral Immune Response and Safety of SARS-CoV-2 Vaccination in Pediatric Inflammatory Bowel Disease. Am J Gastroenterol. 2023 Jan 1;118(1):129-137. doi: 10.14309/ajg.0000000000002016. Epub 2022 Sep 16. PMID: 36114773.

Sazonovs A, Stevens CR, Venkataraman GR, Yuan K, Avila B, Abreu MT, Ahmad T, Allez M, Ananthakrishnan AN, Atzmon G, Baras A, Barrett JC, Barzilai N, Beaugerie L, Beecham A, Bernstein CN, Bitton A, Bokemeyer B, Chan A, Chung D, Cleynen I, Cosnes J, Cutler DJ, Daly A, Damas OM, Datta LW, Dawany N, Devoto M, Dodge S, Ellinghaus E, Fachal L, Farkkila M, Faubion W, Ferreira M, Franchimont D, Gabriel SB, Ge T, Georges M, Gettler K, Giri M, Glaser B, Goerg S, Goyette P, Graham D, Hämäläinen E, Haritunians T, Heap GA, Hiltunen M, Hoeppner M, Horowitz JE, Irving P, Iyer V, Jalas C, Kelsen J, Khalili H, Kirschner BS, Kontula K, Koskela JT, Kugathasan S, Kupcinskas J, Lamb CA, Laudes M, Lévesque C, Levine AP, Lewis JD, Liefferinckx C, Loescher BS, Louis E, Mansfield J, May S, McCauley JL, Mengesha E, Mni M, Moayyedi P, Moran CJ, Newberry RD, O'Charoen S, Okou DT, Oldenburg B, Ostrer H, Palotie A, Paquette J, Pekow J, Peter I, Pierik MJ, Ponsioen CY, Pontikos N, Prescott N, Pulver AE, Rahmouni S, Rice DL, Saavalainen P, Sands B, Sartor RB, Schiff ER, Schreiber S, Schumm LP, Segal AW, Seksik P, Shawky R, Sheikh SZ, Silverberg MS, Simmons A, Skeiceviciene J, Sokol H, Solomonson M, Somineni H, Sun D, Targan S, Turner D, Uhlig HH, van der Meulen AE, Vermeire S, Verstockt S, Voskuil MD, Winter HS, Young J; Belgium IBD Consortium; Cedars-Sinai IBD; International IBD Genetics Consortium; NIDDK IBD Genetics Consortium; NIHR IBD BioResource; Regeneron Genetics Center; SHARE Consortium; SPARC IBD Network; UK IBD Genetics Consortium; Duerr RH, Franke A, Brant SR, Cho J, Weersma RK, Parkes M, Xavier RJ, Rivas MA, Rioux JD, McGovern DPB, Huang H, Anderson CA, Daly MJ. Large-scale sequencing identifies multiple genes and rare variants associated with Crohn's disease susceptibility. Nat Genet. 2022 Sep;54(9):1275-1283. doi: 10.1038/s41588-022-01156-2. Epub 2022 Aug 29. PMID: 36038634; PMCID: PMC9700438.

Liu Z, Liu R, Gao H, Jung S, Gao X, Sun R, Liu X, Kim Y, Lee HS, Kawai Y, Nagasaki M, Umeno J, Tokunaga K, Kinouchi Y, Masamune A, Shi W, Shen C, Guo Z, Yuan K; FinnGen; International Inflammatory Bowel Disease Genetics Consortium; Chinese Inflammatory Bowel Disease Genetics Consortium; Zhu S, Li D, Liu J, Ge T, Cho J, Daly MJ, McGovern DPB, Ye BD, Song K, Kakuta Y, Li M, Huang H. Genetic architecture of the inflammatory bowel diseases across East Asian and European ancestries. Nat Genet. 2023 May;55(5):796-806. doi: 10.1038/s41588-023-01384-0. Epub 2023 May 8. PMID: 37156999; PMCID: PMC10290755.

Kerur B, Fiedler K, Stahl M, Hyams J, Stephens M, Lu Y, Pfefferkorn M, Alkhouri R, Strople J, Kelsen J, Siebold L, Goyal A, Rosh JR, LeLeiko N, Van Limbergen J, Guerrerio AL, Maltz RM, Karam L, Crowley E, Griffiths AM, Heyman MB, Deneau M, Benkov K, Noe J, Moulton D, Pappa H, Galanko J, Snapper S, Muise AM, Kappelman MD, Benchimol EI. Utilization of Antitumor Necrosis Factor Biologics in Very Early Onset Inflammatory Bowel Disease: A Multicenter Retrospective Cohort Study From North America. J Pediatr Gastroenterol Nutr. 2022 Jul 1;75(1):64-69. doi: 10.1097/MPG.0000000000003464. Epub 2022 May 27. PMID: 35622080.

Constant BD, de Zoeten EF, Weinman JP, Albenberg L, Scott FI. Early Anti-Tumor-Necrosis-Factor Therapy for Crohn's Disease-Related Abdominal Abscesses and Phlegmon in Children. Dig Dis Sci. 2023 Mar;68(3):877-888. doi: 10.1007/s10620-022-07604-7. Epub 2022 Jul 5. PMID: 35790702.

Dawwas GK, Weiss A, Constant BD, Parlett LE, Haynes K, Yang JY, Brensinger C, Wu Q, Pate V, Jonsson Funk M, Schaubel DE, Hurtado-Lorenzo A, David Kappelman M, Lewis JD. Development and Validation of Claims-Based Definitions to Identify Incident and Prevalent Inflammatory Bowel Disease in Administrative Healthcare Databases. Inflamm Bowel Dis. 2023 Apr 12:izad053. doi: 10.1093/ibd/izad053. Epub ahead of print. PMID: 37043675.

Constant BD, Baldassano R, Kirsch J, Mitchel EB, Stein R, Albenberg L. Tofacitinib Salvage Therapy for Children Hospitalized for Corticosteroid- and Biologic-Refractory Ulcerative Colitis. J Pediatr Gastroenterol Nutr. 2022 Dec 1;75(6):724-730. doi: 10.1097/MPG.0000000000003616. Epub 2022 Sep 19. PMID: 36122389.

Clarkston K, Karns R, Jegga AG, Sharma M, Fox S, Ojo BA, Minar P, Walters TD, Griffiths AM, Mack DR, Boyle B, LeLeiko NS, Markowitz J, Rosh JR, Patel AS, Shah S, Baldassano RN, Pfefferkorn M, Sauer C, Kugathasan S, Haberman Y, Hyams JS, Denson LA, Rosen MJ. Targeted Assessment of Mucosal Immune Gene Expression Predicts Clinical Outcomes in Children with Ulcerative Colitis. J Crohns Colitis. 2022 Nov 23;16(11):1735-1750. doi: 10.1093/ecco-jcc/jjac075. PMID: 35665804; PMCID: PMC9683081.

Marcovitch L, Focht G, Carmon N, Tersigni C, Ledder O, Lev-Tzion R, Church PC, Hyams JS, Baldassano RN, Bousvaros A, Mack DR, Hussey S, Otley A, Croft NM, Kappelman MD, Griffiths AM, Turner D. Development and Validation of the TUMMY-UC: A Patient-Reported Outcome for Pediatric Ulcerative Colitis. Gastroenterology. 2023 Apr;164(4):610-618.e4. doi: 10.1053/j.gastro.2022.12.006. Epub 2022 Dec 17. PMID: 36539016.

Whaley KG, Xiong Y, Karns R, Hyams JS, Kugathasan S, Boyle BM, Walters TD, Kelsen J, LeLeiko N, Shapiro J, Waddell A, Fox S, Bezold R, Bruns S, Widing R, Haberman Y, Collins MH, Mizuno T, Minar P, D'Haens GR, Denson LA, Vinks AA, Rosen MJ. Multicenter Cohort Study of Infliximab Pharmacokinetics and Therapy Response in Pediatric Acute Severe Ulcerative Colitis. Clin Gastroenterol Hepatol. 2023 May;21(5):1338-1347. doi: 10.1016/j.cgh.2022.08.016. Epub 2022 Aug 27. PMID: 36031093; PMCID: PMC9968822.

Atia O, Pujol-Muncunill G, Navas-López VM, Orlanski-Meyer E, Ledder O, Lev-Tzion R, Focht G, Shteyer E, Stein R, Aloi M, Russell RK, Martin-de-Carpi J, Turner D. Children included in randomised controlled trials of biologics in inflammatory bowel diseases do not represent the real-world patient mix. Aliment Pharmacol Ther. 2022 Sep;56(5):794-801. doi: 10.1111/apt.17092. Epub 2022 Jun 23. PMID: 35735987; PMCID: PMC9542175.

Atia O, Shavit-Brunschwig Z, Mould DR, Stein R, Matar M, Aloi M, Ledder O, Focht G, Urlep D, Hyams J, Broide E, Weiss B, Levine J, Russell RK, Turner D. Outcomes, dosing, and predictors of vedolizumab treatment in children with inflammatory bowel disease (VEDOKIDS): a prospective, multicentre cohort study. Lancet Gastroenterol Hepatol. 2023 Jan;8(1):31-42. doi: 10.1016/S2468-1253(22)00307-7. Epub 2022 Oct 26. PMID: 36306803.

Wilkins BJ, Kelsen JR, Conrad MA. A Pattern-based Pathology Approach to Very Early-onset Inflammatory Bowel Disease: Thinking Beyond Crohn Disease and Ulcerative Colitis. Adv Anat Pathol. 2022 Jan 1;29(1):62-70. doi: 10.1097/PAP.0000000000000327. PMID: 34813528; PMCID: PMC8665089.

Ouahed J, Kelsen JR, Spessott WA, Kooshesh K, Sanmillan ML, Dawany N, Sullivan KE, Hamilton KE, Slowik V, Nejentsev S, Neves JF, Flores H, Chung WK, Wilson A, Anyane-Yeboa K, Wou K, Jain P, Field M, Tollefson S, Dent MH, Li D, Naito T, McGovern DPB, Kwong AC, Taliaferro F, Ordovas-Montanes J, Horwitz BH, Kotlarz D, Klein C, Evans J, Dorsey J, Warner N, Elkadri A, Muise AM, Goldsmith J, Thompson B, Engelhardt KR, Cant AJ, Hambleton S, Barclay A, Toth-Petroczy A, Vuzman D, Carmichael N, Bodea C, Cassa CA, Devoto M, Maas RL, Behrens EM, Giraudo CG, Snapper SB. Variants in STXBP3 are Associated with Very Early Onset Inflammatory Bowel Disease, Bilateral Sensorineural Hearing Loss and Immune Dysregulation. J Crohns Colitis. 2021 Nov 8;15(11):1908-1919. doi: 10.1093/ecco-jcc/jjab077. PMID: 33891011; PMCID: PMC8575043.

Atia O, Pujol-Muncunill G, Navas-López VM, Orlanski-Meyer E, Ledder O, Lev-Tzion R, Focht G, Shteyer E, Stein R, Aloi M, Russell RK, Martin-de-Carpi J, Turner D. Children included in randomised controlled trials of biologics in inflammatory bowel diseases do not represent the real-world patient-mix. Aliment Pharmacol Ther. 2022 Jun 23. doi: 10.1111/apt.17092. Epub ahead of print. PMID: 35735987.

Hannah WB, Ong RC, Moreno MN, Pendyal S, Abdelmalak M, Kelsen J, McGreal NM, Kishnani PS. Very early-onset inflammatory bowel disease: Novel description in glycogen storage disease type Ia. Mol Genet Metab Rep. 2022 Feb 15;31:100848. doi: 10.1016/j.ymgmr.2022.100848. PMID: 35242580; PMCID: PMC8857073.

Marcovitch L, Focht G, Horesh A, Shosberger A, Hyams J, Bousvaros A, Hale AE, Baldassano R, Otley A, Mack DR, Kappelman MD, Griffiths AM, Turner D. Agreement on Symptoms Between Children With Ulcerative Colitis and Their Caregivers: Towards Developing the TUMMY-UC. J Pediatr Gastroenterol Nutr. 2021 Aug 1;73(2):e35-e38. doi: 10.1097/MPG.0000000000003120. PMID: 33720091.
38. Breton J, Tanes C, Tu V, Albenberg L, Rowley S, Devas N, Hwang R, Kachelries K, Wu GD, Baldassano RN, Bittinger K, Mattei P. A Microbial Signature for Pediatric Perianal Crohn's Disease. J Crohns Colitis. 2022 Feb 25:jjac032. doi: 10.1093/ecco-jcc/jjac032. Epub ahead of print. PMID: 35211723.

Clarkston K, Karns R, Jegga AG, Sharma M, Fox S, Ojo BA, Minar P, Walters TD, Griffiths AM, Mack DR, Boyle B, LeLeiko NS, Markowitz J, Rosh JR, Patel AS, Shah S, Baldassano RN, Pfefferkorn M, Sauer C, Kugathasan S, Haberman Y, Hyams JS, Denson LA, Rosen MJ. Targeted Assessment of Mucosal Immune Gene Expression Predicts Clinical Outcomes in Children with Ulcerative Colitis. J Crohns Colitis. 2022 Jun 4:jjac075. doi: 10.1093/ecco-jcc/jjac075. Epub ahead of print. PMID: 35665804.

Lichtenstein GR, Shahabi A, Seabury SA, Lakdawalla DN, Espinosa OD, Green S, Brauer M, Baldassano RN. Increased Lifetime Risk of Intestinal Complications and Extraintestinal Manifestations in Crohn's Disease and Ulcerative Colitis. Gastroenterol Hepatol (N Y). 2022 Jan;18(1):32-43. PMID: 35505770; PMCID: PMC9053498.

Mo A, Nagpal S, Gettler K, Haritunians T, Giri M, Haberman Y, Karns R, Prince J, Arafat D, Hsu NY, Chuang LS, Argmann C, Kasarskis A, Suarez-Farinas M, Gotman N, Mengesha E, Venkateswaran S, Rufo PA, Baker SS, Sauer CG, Markowitz J, Pfefferkorn MD, Rosh JR, Boyle BM, Mack DR, Baldassano RN, Shah S, LeLeiko NS, Heyman MB, Griffiths AM, Patel AS, Noe JD, Davis Thomas S, Aronow BJ, Walters TD, McGovern DPB, Hyams JS, Kugathasan S, Cho JH, Denson LA, Gibson G. Stratification of risk of progression to colectomy in ulcerative colitis via measured and predicted gene expression. Am J Hum Genet. 2021 Sep 2;108(9):1765-1779. doi: 10.1016/j.ajhg.2021.07.013. Epub 2021 Aug 26. PMID: 34450030; PMCID: PMC8456180.

Sarbagili-Shabat C, Albenberg L, Van Limbergen J, Pressman N, Otley A, Yaakov M, Wine E, Weiner D, Levine A. A Novel UC Exclusion Diet and Antibiotics for Treatment of Mild to Moderate Pediatric Ulcerative Colitis: A Prospective Open-Label Pilot Study. Nutrients. 2021 Oct 23;13(11):3736. doi: 10.3390/nu13113736. PMID: 34835992; PMCID: PMC8622458.

Conrad MA, Kelsen JR. Clostridioides difficile Infection in Pediatric Inflammatory Bowel Disease: A Clinician's Dilemma. J Pediatric Infect Dis Soc. 2021 Nov 17;10(Supplement_3):S41-S45. doi:10.1093/jpids/piab069. PMID: 34343321; PMCID: PMC8600020.

Rudra S, Shaul E, Conrad M, Patel T, Moore A, Dawany N, Canavan MC, Sullivan KE, Behrens E, Kelsen JR. Ruxolitinib: Targeted Approach for Treatment of Autoinflammatory Very Early Onset Inflammatory Bowel Disease. Clin Gastroenterol Hepatol. 2022 Jun;20(6):1408-1410.e2. doi: 10.1016/j.cgh.2021.07.040. Epub 2021 Jul 27. PMID: 34329777; PMCID: PMC8792097.

Moore H, Dubes L, Fusillo S, Baldassano R, Stein R. Tofacitinib Therapy in Children and Young Adults With Pediatric-onset Medically Refractory Inflammatory Bowel Disease. J Pediatr Gastroenterol Nutr. 2021 Sep 1;73(3):e57-e62. doi: 10.1097/MPG.0000000000003190. PMID: 34091545.

Nicholson MR, Alexander E, Ballal S, Davidovics Z, Docktor M, Dole M, Gisser JM, Goyal A, Hourigan SK, Jensen MK, Kaplan JL, Kellermayer R, Kelsen JR, Kennedy MA, Khanna S, Knackstedt ED, Lentine J, Lewis JD, Michail S, Mitchell PD, Oliva-Hemker M, Patton T, Queliza K, Sidhu S, Solomon AB, Suskind DL, Weatherly M, Werlin S, de Zoeten EF, Kahn SA; North American Society of Pediatric Gastroenterology and Nutrition Faecal Microbiota Transplantation Special Interest Group. Efficacy and Outcomes of Faecal Microbiota Transplantation for Recurrent Clostridioides difficile Infection in Children with Inflammatory Bowel Disease. J Crohns Colitis. 2022 Jun 24;16(5):768-777. doi: 10.1093/ecco-jcc/jjab202. PMID: 34788420; PMCID: PMC9228903.

Liang G, Cobián-Güemes AG, Albenberg L, Bushman F. The gut virome in inflammatory bowel diseases. Curr Opin Virol. 2021 Dec;51:190-198. doi: 10.1016/j.coviro.2021.10.005. Epub 2021 Nov 8. PMID: 34763180.

Breton J, Witmer CM, Zhang Y, Downing M, Stevenson J, McDermott J, Siddique SM, Grossman AB. Utilization of an Electronic Medical Record-integrated Dashboard Improves Identification and Treatment of Anemia and Iron Deficiency in Pediatric Inflammatory Bowel Disease. Inflamm Bowel Dis. 2021 Aug 19;27(9):1409-1417. doi: 10.1093/ibd/izaa288. PMID: 33165613.

Hyams JS, Brimacombe M, Haberman Y, Walters T, Gibson G, Mo A, Mack D, Griffiths A, Boyle B, LeLeiko N, Markowitz J, Rosh J, Patel A, Shah S, Baldassano R, Pfefferkorn M, Sauer C, Dailey J, Venkateswaran S, Kugathasan S, Denson LA. Clinical and Host Biological Factors Predict Colectomy Risk in Children Newly Diagnosed With Ulcerative Colitis. Inflamm Bowel Dis. 2022 Feb 1;28(2):151-160. doi: 10.1093/ibd/izab061. PMID: 33904583; PMCID: PMC8804885.

Ta AD, Ollberding NJ, Karns R, Haberman Y, Alazraki AL, Hercules D, Baldassano R, Markowitz J, Heyman MB, Kim S, Kirschner B, Shapiro JM, Noe J, Oliva-Hemker M, Otley A, Pfefferkorn M, Kellermayer R, Snapper S, Rabizadeh S, Xavier R, Dubinsky M, Hyams J, Kugathasan S, Jegga AG, Dillman JR, Denson LA. Association of Baseline Luminal Narrowing With Ileal Microbial Shifts and Gene Expression Programs and Subsequent Transmural Healing in Pediatric Crohn Disease. Inflamm Bowel Dis. 2021 Oct 20;27(11):1707-1718. doi: 10.1093/ibd/izaa339. PMID: 33452801;

Holbein CE, Plevinsky J, Patel T, Conrad MC, Kelsen JR. Pediatric Global Health in Children with Very Early-Onset Inflammatory Bowel Disease. J Pediatr Psychol. 2021 Aug 11;46(7):747-756. doi: 10.1093/jpepsy/jsab035. PMID: 34313785; PMCID: PMC8357223.

Buckley LH, Xiao R, Perman MJ, Grossman AB, Weiss PF. Psoriasis Associated With Tumor Necrosis Factor Inhibitors in Children With Inflammatory Diseases. Arthritis Care Res (Hoboken). 2021 Feb;73(2):215-220. doi: 10.1002/acr.24100. Epub 2021 Jan 3. Erratum in: Arthritis Care Res (Hoboken). 2021 May;73(5):764. PMID: 31646743; PMCID: PMC8176628.

Bushman FD, Conrad M, Ren Y, Zhao C, Gu C, Petucci C, Kim MS, Abbas A, Downes KJ, Devas N, Mattei LM, Breton J, Kelsen J, Marakos S, Galgano A, Kachelries K, Erlichman J, Hart JL, Moraskie M, Kim D, Zhang H, Hofstaedter CE, Wu GD, Lewis JD, Zackular JP, Li H, Bittinger K, Baldassano R. Multi-omic Analysis of the Interaction between Clostridioides difficile Infection and Pediatric Inflammatory Bowel Disease. Cell Host Microbe. 2020 Sep 9;28(3):422-433.e7. doi: 10.1016/j.chom.2020.07.020. Epub 2020 Aug 20. PMID: 32822584.
Conrad MA, Kelsen JR. Editorial to Temporal Gut Microbial Changes Predict Recurrent Clostridium difficile Infection in Patients With and Without Ulcerative Colitis. Inflamm Bowel Dis. 2020 Oct 23;26(11):1759-1760. doi: 10.1093/ibd/izz336. PMID: 31968096; PMCID: PMC8243268.

Dou Y, Maurer K, Conrad M, Patel T, Shraim R, Sullivan KE, Kelsen J. Mucosal Invariant T cells are Diminished in Very Early-Onset Inflammatory Bowel Disease. J Pediatr Gastroenterol Nutr. 2021 Jun 7. doi: 10.1097/MPG.0000000000003189. Epub ahead of print. PMID: 34117197.
Goyal A, Zheng Y, Albenberg LG, Stoner NL, Hart L, Alkhouri R, Hampson K, Ali S, Cho-Dorado M, Goyal RK, Grossman A. Anemia in Children With Inflammatory Bowel Disease: A Position Paper by the IBD Committee of the North American Society of Pediatric Gastroenterology, Hepatology and Nutrition. J Pediatr Gastroenterol Nutr. 2020 Oct;71(4):563-582. doi: 10.1097/MPG.0000000000002885. PMID: 32947565.

Haberman Y, Minar P, Karns R, Dexheimer PJ, Ghandikota S, Tegge S, Shapiro D, Shuler B, Venkateswaran S, Braun T, Ta A, Walters TD, Baldassano RN, Noe JD, Rosh J, Markowitz J, Dotson JL, Mack DR, Kellermayer R, Griffiths AM, Heyman MB, Baker SS, Moulton D, Patel AS, Gulati AS, Steiner SJ, LeLeiko N, Otley A, Oliva-Hemker M, Ziring D, Gokhale R, Kim S, Guthery SL, Cohen SA, Snapper S, Aronow BJ, Stephens M, Gibson G, Dillman JR, Dubinsky M, Hyams JS, Kugathasan S, Jegga AG, Denson LA. Mucosal Inflammatory and Wound Healing Gene Programs Reveal Targets for Stricturing Behavior in Pediatric Crohn's Disease. J Crohns Colitis. 2020 Aug 8;15(2):273–86. doi: 10.1093/ecco-jcc/jjaa166. Epub ahead of print. PMID: 32770196; PMCID: PMC7904088.

Havele SA, Clark AK, Oboite M, Conrad MA, Perman MJ, Rubin AI, Treat JR. Bowel-associated dermatosis-arthritis syndrome in a child with very early onset inflammatory bowel disease. Pediatr Dermatol. 2021 May;38(3):697-698. doi: 10.1111/pde.14544. Epub 2021 Mar 21. PMID: 33749007.

Hung HH, Lee HC, Yeung CY, Wang NL, Tang TY, Winter HS, Kelsen JR, Jiang CB. Importance of early detection of infantile inflammatory bowel disease with defective IL-10 pathway: A case report. Medicine (Baltimore). 2021 May 28;100(21):e25868. doi: 10.1097/MD.0000000000025868. PMID: 34032699; PMCID: PMC8154448.

Hyams JS, Brimacombe M, Haberman Y, Walters T, Gibson G, Mo A, Mack D, Griffiths A, Boyle B, LeLeiko N, Markowitz J, Rosh J, Patel A, Shah S, Baldassano R, Pfefferkorn M, Sauer C, Dailey J, Venkateswaran S, Kugathasan S, Denson LA. Clinical and Host Biological Factors Predict Colectomy Risk in Children Newly Diagnosed With Ulcerative Colitis. Inflamm Bowel Dis. 2021 Apr 27:izab061. doi: 10.1093/ibd/izab061. Epub ahead of print. PMID: 33904583.

Kelsen JR, Dawany N, Conrad MA, Karakasheva TA, Maurer K, Wei JM, Uman S, Dent MH, Behera R, Bryant LM, Ma X, Moreira L, Chatterji P, Shraim R, Merz A, Mizuno R, Simon LA, Muir AB, Giraudo C, Behrens EM, Whelan KA, Devoto M, Russo PA, Andres SF, Sullivan KE, Hamilton KE. Colonoids From Patients With Pediatric Inflammatory Bowel Disease Exhibit Decreased Growth Associated With Inflammation Severity and Durable Upregulation of Antigen Presentation Genes. Inflamm Bowel Dis. 2021 Jan 19;27(2):256-267. doi: 10.1093/ibd/izaa145. PMID: 32556182; PMCID: PMC7813751.

Lewis JD, Sandler R, Brotherton C, Brensinger C, Li H, Kappelman MD, Daniel SG, Bittinger K, Albenberg L, Valentine JF, Hanson J, Suskind D, Meyer A, Compher CW, Bewtra M, Saxena A, Dobes A, Cohen B, Flynn AD, Fischer M, Saha S, Swaminath A, Yacyshyn B, Scherl E, Horst S, Curtis JR, Braly K, Nessel L, McCauley M, McKeever L, Herfarth H; DINE-CD Study Group. A Randomized Trial Comparing the Specific Carbohydrate Diet to a Mediterranean Diet in Adults with Crohn's Disease. Gastroenterology. 2021 May 27:S0016-5085(21)03069-9. doi: 10.1053/j.gastro.2021.05.047. Epub ahead of print. PMID: 34052278.

Liang G, Conrad MA, Kelsen JR, Kessler LR, Breton J, Albenberg LG, Marakos S, Galgano A, Devas N, Erlichman J, Zhang H, Mattei L, Bittinger K, Baldassano RN, Bushman FD. Dynamics of the Stool Virome in Very Early-Onset Inflammatory Bowel Disease. J Crohns Colitis. 2020 Nov 7;14(11):1600-1610. doi: 10.1093/ecco-jcc/jjaa094. PMID: 32406906; PMCID: PMC7648169.

Mack DR, Saul B, Boyle B, Griffiths A, Sauer C, Markowitz J, LeLeiko N, Keljo D, Rosh JR, Baker SS, Steiner S, Heyman MB, Patel AS, Baldassano R, Noe J, Rufo P, Kugathasan S, Walters T, Marquis A, Thomas SM, Denson L, Hyams J; PROTECT STUDY GROUP. Analysis of Using the Total White Blood Cell Count to Define Severe New-onset Ulcerative Colitis in Children. J Pediatr Gastroenterol Nutr. 2020 Sep;71(3):354-360. doi: 10.1097/MPG.0000000000002797. PMID: 32520830.

Marcovitch L, Focht G, Horesh A, Shosberger A, Hyams J, Bousvaros A, Hale AE, Baldassano R, Otley A, Mack DR, Kappelman MD, Griffiths AM, Turner D. Agreement on Symptoms Between Children With Ulcerative Colitis and Their Caregivers: Towards Developing the TUMMY-UC. J Pediatr Gastroenterol Nutr. 2021 Mar 4. doi: 10.1097/MPG.0000000000003120. Epub ahead of print. PMID: 33720091.
Mitchel EB, Paul A, El-Ali A, Cheng PC, Albenberg LG. Drug-induced Lung Disease Associated With Ustekinumab in a Pediatric Patient With Crohn Disease. J Pediatr Gastroenterol Nutr. 2020 Nov;71(5):e143-e145. doi: 10.1097/MPG.0000000000002783. PMID: 33093382.

Mitchel EB, Rosenbaum S, Gaeta C, Huang J, Raffini LJ, Baldassano RN, Denburg MR, Albenberg L. Venous Thromboembolism in Pediatric Inflammatory Bowel Disease: A Case-Control Study. J Pediatr Gastroenterol Nutr. 2021 May 1;72(5):742-747. doi: 10.1097/MPG.0000000000003078. PMID: 33605670.

Moore H, Dubes L, Fusillo S, Baldassano R, Stein R. Tofacitinib Therapy in Children and Young Adults with Pediatric-Onset Medically-Refractory Inflammatory Bowel Disease. J Pediatr Gastroenterol Nutr. 2021 Jun 1. doi: 10.1097/MPG.0000000000003190. Epub ahead of print. PMID: 34091545.

Moore H, Wechsler J, Frost C, Whiteside E, Baldassano R, Markowitz J, Muir AB. Comorbid Diagnosis of Eosinophilic Esophagitis and Inflammatory Bowel Disease in the Pediatric Population. J Pediatr Gastroenterol Nutr. 2021 Mar 1;72(3):398-403. doi: 10.1097/MPG.0000000000003002. PMID: 33230079.

Ouahed J, Kelsen JR, Spessott WA, Kooshesh K, Sanmillan ML, Dawany N, Sullivan KE, Hamilton K, Slowik V, Nejentsev S, Neves JF, Flores H, Chung WK, Wilson A, Yeboa KA, Wou K, Jain P, Field M, Tollefson S, Dent MH, Li D, Naito T, McGovern DPB, Kwong AC, Taliaferro F, Ordovas-Montanes J, Horwitz B, Kotlarz D, Klein C, Evans J, Dorsey J, Warner N, Elkadri A, Muise AM, Goldsmith J, Thompson B, Engelhardt KR, Cant AJ, Hambleton S, Barclay A, Toth-Petroczy A, Vuzman D, Carmichael N, Bodea C, Cassa CA, Devoto M, Maas RL, Behrens EM, Giraudo CG, Snapper SB. Variants in STXBP3 Are Associated With Very Early Onset Inflammatory Bowel Disease, Bilateral Sensorineural Hearing Loss and Immune Dysregulation. J Crohns Colitis. 2021 Apr 23:jjab077. doi: 10.1093/ecco-jcc/jjab077. Epub ahead of print. PMID: 33891011.

Palchaudhuri S, Albenberg L, Lewis JD. Diet Recommendations for Hospitalized Patients With Inflammatory Bowel Disease: Better Options Than Nil Per Os. Crohns Colitis 360. 2020 Oct;2(4):otaa059. doi: 10.1093/crocol/otaa059. Epub 2020 Jul 17. PMID: 33954288; PMCID: PMC8096188.

Roy Paladhi U, Harb AH, Daniel SG, Dawwas GK, Schnellinger EM, Wollack C, Aberra FN, Bewtra M, Green JA, Klaproth JA, Lichtenstein GR, Saxena A, Berera S, Buchner A, Mehta SJ, Osterman MT, Rashid F, Tomov V, Caldera F, Sumona S, Mahadevan U, Roy A, Nessel L, Wu GD, Bittinger K, Lewis JD. The Impact of Introducing Patient-Reported Inflammatory Bowel Disease Symptoms via Electronic Survey on Clinic Visit Length, Patient and Provider Satisfaction, and the Environment Microbiome. Inflamm Bowel Dis. 2021 Apr 15;27(5):746-750. doi: 10.1093/ibd/izaa356. PMID: 33452800.

Smith SA, Ogawa SA, Chau L, Whelan KA, Hamilton KE, Chen J, Tan L, Chen EZ, Keilbaugh S, Fogt F, Bewtra M, Braun J, Xavier RJ, Clish CB, Slaff B, Weljie AM, Bushman FD, Lewis JD, Li H, Master SR, Bennett MJ, Nakagawa H, Wu GD. Mitochondrial dysfunction in inflammatory bowel disease alters intestinal epithelial metabolism of hepatic acylcarnitines. J Clin Invest. 2021 Jan 4;131(1):e133371. doi: 10.1172/JCI133371. PMID: 33141762; PMCID: PMC7773399.

Somineni HK, Nagpal S, Venkateswaran S, Cutler DJ, Okou DT, Haritunians T, Simpson CL, Begum F, Datta LW, Quiros AJ, Seminerio J, Mengesha E, Alexander JS, Baldassano RN, Dudley-Brown S, Cross RK, Dassopoulos T, Denson LA, Dhere TA, Iskandar H, Dryden GW, Hou JK, Hussain SZ, Hyams JS, Isaacs KL, Kader H, Kappelman MD, Katz J, Kellermayer R, Kuemmerle JF, Lazarev M, Li E, Mannon P, Moulton DE, Newberry RD, Patel AS, Pekow J, Saeed SA, Valentine JF, Wang MH, McCauley JL, Abreu MT, Jester T, Molle-Rios Z, Palle S, Scherl EJ, Kwon J, Rioux JD, Duerr RH, Silverberg MS, Zwick ME, Stevens C, Daly MJ, Cho JH, Gibson G, McGovern DPB, Brant SR, Kugathasan S. Whole-genome sequencing of African Americans implicates differential genetic architecture in inflammatory bowel disease. Am J Hum Genet. 2021 Mar 4;108(3):431-445. doi: 10.1016/j.ajhg.2021.02.001. Epub 2021 Feb 17. PMID: 33600772; PMCID: PMC8008495.

Ta AD, Ollberding NJ, Karns R, Haberman Y, Alazraki AL, Hercules D, Baldassano R, Markowitz J, Heyman MB, Kim S, Kirschner B, Shapiro JM, Noe J, Oliva-Hemker M, Otley A, Pfefferkorn M, Kellermayer R, Snapper S, Rabizadeh S, Xavier R, Dubinsky M, Hyams J, Kugathasan S, Jegga AG, Dillman JR, Denson LA. Association of Baseline Luminal Narrowing With Ileal Microbial Shifts and Gene Expression Programs and Subsequent Transmural Healing in Pediatric Crohn Disease. Inflamm Bowel Dis. 2021 Jan 16:izaa339. doi: 10.1093/ibd/izaa339. Epub ahead of print. PMID: 33452801.

Turpin W, Bedrani L, Espin-Garcia O, Xu W, Silverberg MS, Smith MI, Garay JAR, Lee SH, Guttman DS, Griffiths A, Moayyedi P, Panaccione R, Huynh H, Steinhart HA, Aumais G, Dieleman LA, Turner D; CCC IBD GEM Project research team, Paterson AD, Croitoru K. Associations of NOD2 polymorphisms with Erysipelotrichaceae in stool of in healthy first degree relatives of Crohn's disease subjects. BMC Med Genet. 2020 Oct 15;21(1):204. doi: 10.1186/s12881-020-01115-w. PMID: 33059653; PMCID: PMC7566148.

Turpin W, Lee SH, Raygoza Garay JA, Madsen KL, Meddings JB, Bedrani L, Power N, Espin-Garcia O, Xu W, Smith MI, Griffiths AM, Moayyedi P, Turner D, Seidman EG, Steinhart AH, Marshall JK, Jacobson K, Mack D, Huynh H, Bernstein CN, Paterson AD; Crohn’s and Colitis Canada Genetic Environmental Microbial Project Research Consortium; CCC GEM Project recruitment site directors include Maria Abreu, Croitoru K. Increased Intestinal Permeability Is Associated With Later Development of Crohn's Disease. Gastroenterology. 2020 Dec;159(6):2092-2100.e5. doi: 10.1053/j.gastro.2020.08.005. Epub 2020 Aug 10. PMID: 32791132.

Breton J, Kastl A, Conrad MA, Baldassano RN. Positioning Biologic Therapies in the Management of Pediatric Inflammatory Bowel Disease. Gastroenterol Hepatol (N Y). 2020 Aug;16(8):400-414. PMID: 34035746; PMCID: PMC8132662.

Breton J, Witmer CM, Zhang Y, Downing M, Stevenson J, McDermott J, Siddique SM, Grossman AB. Utilization of an Electronic Medical Record-integrated Dashboard Improves Identification and Treatment of Anemia and Iron Deficiency in Pediatric Inflammatory Bowel Disease. Inflamm Bowel Dis. 2020 Nov 9:izaa288. doi: 10.1093/ibd/izaa288. Epub ahead of print. PMID: 33165613.

Moore H, Dolce P, Devas N, Baldassano R, Martinelli M. Post-induction infliximab trough levels and disease activity in the clinical evolution of pediatric ulcerative colitis. United European Gastroenterol J. 2020 May;8(4):425-435. doi: 10.1177/2050640620912877. Epub 2020 Mar 12. PMID: 32213038; PMCID: PMC7226697.

Turner D, Bishai J, Reshef L, Abitbol G, Focht G, Marcus D, Ledder O, Lev-Tzion R, Orlanski-Meyer E, Yerushalmi B, Aloi M, Griffiths AM, Albenberg L, Kolho KL, Assa A, Cohen S, Gophna U, Vlamakis H, Lurz E, Levine A. Antibiotic Cocktail for Pediatric Acute Severe Colitis and the Microbiome: The PRASCO Randomized Controlled Trial. Inflamm Bowel Dis. 2019 Dec 13:izz298. doi: 10.1093/ibd/izz298. Epub ahead of print. PMID: 31833543.

Conrad MA, Kelsen JR. The Treatment of Pediatric Inflammatory Bowel Disease with Biologic Therapies. Curr Gastroenterol Rep. 2020 Jun 15;22(8):36. doi: 10.1007/s11894-020-00773-3. PMID: 32542562.

El-Matary W, Guthery SL, Amir AZ, DiGuglielmo M, Draijer LG, Furuya KN, Gupta N, Hochberg JT, Horslen S, Kerkar N, Koot BGP, Laborda TJ, Loomes KM, Mack C, Martinez M, Miethke A, Miloh T, Mogul D, Mohammed S, Moroz S, Ovchinsky N, Perito ER, Rao G, Ricciuto A, Sathya P, Schwarz KB, Shah U, Singh R, Soufi N, Valentino PL, Zizzo A, Deneau MR. Colorectal Dysplasia and Cancer in Pediatric-Onset Ulcerative Colitis Associated With Primary Sclerosing Cholangitis. Clin Gastroenterol Hepatol. 2020 Apr 29:S1542-3565(20)30600-5. doi: 10.1016/j.cgh.2020.04.055. Epub ahead of print. PMID: 32360820.

Forrest CB, Forrest KD, Clegg JL, de la Motte A, Amaral S, Grossman AB, Furth SL. Establishing the content validity of PROMIS Pediatric pain interference, fatigue, sleep disturbance, and sleep-related impairment measures in children with chronic kidney disease and Crohn's disease. J Patient Rep Outcomes. 2020 Feb 12;4(1):11. doi: 10.1186/s41687-020-0178-2. PMID: 32052205; PMCID: PMC7016154.

Kelsen JR, Dawany N, Conrad MA, Karakasheva TA, Maurer K, Wei JM, Uman S, Dent MH, Behera R, Bryant LM, Ma X, Moreira L, Chatterji P, Shraim R, Merz A, Mizuno R, Simon LA, Muir AB, Giraudo C, Behrens EM, Whelan KA, Devoto M, Russo PA, Andres SF, Sullivan KE, Hamilton KE. Colonoids From Patients With Pediatric Inflammatory Bowel Disease Exhibit Decreased Growth Associated With Inflammation Severity and Durable Upregulation of Antigen Presentation Genes. Inflamm Bowel Dis. 2020 Jun 19:izaa145. doi: 10.1093/ibd/izaa145. Epub ahead of print. PMID: 32556182.

Kelsen JR, Sullivan KE, Rabizadeh S, Singh N, Snapper S, Elkadri A, Grossman AB. North American Society for Pediatric Gastroenterology, Hepatology, and Nutrition Position Paper on the Evaluation and Management for Patients With Very Early-onset Inflammatory Bowel Disease. J Pediatr Gastroenterol Nutr. 2020 Mar;70(3):389-403. doi: 10.1097/MPG.0000000000002567. PMID: 32079889.

Lekbua A, Ouahed J, O'Connell AE, Kahn SA, Goldsmith JD, Imamura T, Duncan CN, Kelsen JR, Worthey E, Snapper SB, Softic S. Risk-factors Associated With Poor Outcomes in VEO-IBD Secondary to XIAP Deficiency: A Case Report and Literature Review. J Pediatr Gastroenterol Nutr. 2019 Jul;69(1):e13-e18. doi: 10.1097/MPG.0000000000002297. PMID: 31232887; PMCID: PMC6607918.
Liang G, Conrad MA, Kelsen JR, Kessler LR, Breton J, Albenberg LG, Marakos S, Galgano A, Devas N, Erlichman J, Zhang H, Mattei L, Bittinger K, Baldassano RN, Bushman FD. The dynamics of the stool virome in very early onset inflammatory bowel disease. J Crohns Colitis. 2020 May 14:jjaa094. doi: 10.1093/ecco-jcc/jjaa094. Epub ahead of print. PMID: 32406906.

Lichtenstein GR, Shahabi A, Seabury SA, Lakdawalla DN, Espinosa OD, Green S, Brauer M, Baldassano RN. Lifetime Economic Burden of Crohn's Disease and Ulcerative Colitis by Age at Diagnosis. Clin Gastroenterol Hepatol. 2020 Apr;18(4):889-897.e10. doi: 10.1016/j.cgh.2019.07.022. Epub 2019 Jul 18. PMID: 31326606.

Mack DR, Saul B, Boyle B, Griffiths A, Sauer C, Markowitz J, LeLeiko N, Keljo D, Rosh JR, Baker SS, Steiner S, Heyman MB, Patel AS, Baldassano R, Noe J, Rufo P, Kugathasan S, Walters T, Marquis A, Thomas SM, Denson L, Hyams J; PROTECT STUDY GROUP. Analysis of Using the Total White Blood Cell Count to Define Severe New Onset Ulcerative Colitis in Children. J Pediatr Gastroenterol Nutr. 2020 Jun 9. doi: 10.1097/MPG.0000000000002797. Epub ahead of print. PMID: 32520830.

Mitchel E, Diamond T, Albenberg L. Venous Thrombosis in Pediatric Inflammatory Bowel Disease. J Pediatr. 2020 Jan;216:213-217. doi: 10.1016/j.jpeds.2019.09.034. Epub 2019 Oct 11. PMID: 31610937.

Tokarz R, Hyams JS, Mack DR, Boyle B, Griffiths AM, LeLeiko NS, Sauer CG, Shah S, Markowitz J, Baker SS, Rosh J, Baldassano RN, Kugathasan S, Walters T, Tagliafierro T, Sameroff S, Lee B, Che X, Oleynik A, 3Denson LA, Lipkin WI. Characterization of Stool Virome in Children Newly Diagnosed With Moderate to Severe Ulcerative Colitis. Inflamm Bowel Dis. 2019 Sep 18;25(10):1656-1662. doi: 10.1093/ibd/izz099. PMID: 31112614; PMCID: PMC7108593.

Conrad MA, Kelsen JR. Genomic and Immunologic Drivers of Very Early-Onset Inflammatory Bowel Disease. Pediatr Dev Pathol. 2019 May-Jun;22(3):183-193. doi: 10.1177/1093526619834807. Epub 2019 Mar 6. PMID: 30841788; PMCID: PMC6942488.
Albenberg L, Brensinger CM, Wu Q, Gilroy E, Kappelman MD, Sandler RS, Lewis JD. A Diet Low in Red and Processed Meat Does Not Reduce Rate of Crohn's Disease Flares. Gastroenterology. 2019 Jul;157(1):128-136.e5. doi: 10.1053/j.gastro.2019.03.015. Epub 2019 Mar 11. PMID: 30872105; PMCID: PMC6726378.

Turner D, Griffiths AM, Wilson D, Mould DR, Baldassano RN, Russell RK, Dubinsky M, Heyman MB, de Ridder L, Hyams J, Martin de Carpi J, Conklin L, Faubion WA, Koletzko S, Bousvaros A, Ruemmele FM. Designing clinical trials in paediatric inflammatory bowel diseases: a PIBDnet commentary. Gut. 2020 Jan;69(1):32-41. doi: 10.1136/gutjnl-2018-317987. Epub 2019 Apr 12. PMID: 30979718.

Ballengee CR, Stidham RW, Liu C, Kim MO, Prince J, Mondal K, Baldassano R, Dubinsky M, Markowitz J, Leleiko N, Hyams J, Denson L, Kugathasan S. Association Between Plasma Level of Collagen Type III Alpha 1 Chain and Development of Strictures in Pediatric Patients With Crohn's Disease. Clin Gastroenterol Hepatol. 2019 Aug;17(9):1799-1806. doi: 10.1016/j.cgh.2018.09.008. Epub 2018 Sep 10. PMID: 30213581; PMCID: PMC6531351.
Conrad MA, Kelsen JR. Editorial to Temporal Gut Microbial Changes Predict Recurrent Clostridium difficile Infection in Patients With and Without Ulcerative Colitis. Inflamm Bowel Dis. 2020 Jan 22:izz336. doi: 10.1093/ibd/izz336. Epub ahead of print. PMID: 31968096.

Kelsen JR, Sullivan KE, Rabizadeh S, Singh N, Snapper S, Elkadri A, Grossman AB. NASPGHAN Position Paper on The Evaluation and Management for Patients with Very Early-Onset Inflammatory Bowel Disease (VEO-IBD). J Pediatr Gastroenterol Nutr. 2019 Dec 30. doi: 10.1097/MPG.0000000000002567. Epub ahead of print. PMID: 31899730.

Mitchel EB, Paul A, El-Ali A, Cheng PY, Albenberg LG. Drug Induced Lung Disease Associated with Ustekinumab in a Pediatric Patient with Crohn's Disease. J Pediatr Gastroenterol Nutr. 2020 May 12. doi: 10.1097/MPG.0000000000002783. Epub ahead of print. PMID: 32404766.

Breton J, Kastl A, Hoffmann N, Rogers R, Grossman AB, Mamula P, Kelsen JR, Baldassano RN, Albenberg L. Efficacy of Combination Antibiotic Therapy for Refractory Pediatric Inflammatory Bowel Disease. Inflamm Bowel Dis. 2019 Aug 20;25(9):1586-1593. doi: 10.1093/ibd/izz006. PMID: 30715364; PMCID: PMC6939824.

Buckley LH, Xiao R, Perman MJ, Grossman AB, Weiss PF. Psoriasis Associated with Tumor Necrosis Factor-Alpha Inhibitors in Children with Inflammatory Diseases. Arthritis Care Res (Hoboken). 2019 Oct 23. doi: 10.1002/acr.24100. Epub ahead of print. PMID: 31646743.

Ballengee Cortney R, Stidham Ryan W, Liu Chunyan, Kim Mi-Ok, Prince Jarod, Mondal Kajari, Baldassano Robert, Dubinsky Marla, Markowitz James, Leleiko Neal, Hyams Jeffrey, Denson Lee, Kugathasan Subra: Association Between Plasma Level of Collagen Type III alpha 1 Chain and Development of Strictures in Pediatric Patients With Crohn's Disease. Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association Sep 2018.

Breton J, Kastl A, Hoffmann N, Rogers R, Grossman AB, Mamula P, Kelsen JR, Baldassano RN, Albenberg L: Efficacy of combination antibiotic therapy for refractory pediatric inflammatory bowel disease. Inflammatory Bowel Diseases Feb 2019 Notes: [Epub ahead of print]

Chenthan, Ballengee Cortney R, Liu Chunyan, Kim Mi-Ok, Baker Susan S, Baldassano Robert N, Cohen Stanley A, Crandall Wallace V, Denson Lee A, Dubinsky Marla C, Evans Jonathan, Gokhale Ranjana, Griffiths Anne, Guthery Stephen L, Oliva-Hemker Maria, Heyman Melvin B, Keljo David, Kellermayer Richard, Leleiko Neal S, Mack David R, Markowitz James F, Moulton Dedrick E, Noe Joshua D, Otley Anthony R, Patel Ashish S, Pfefferkorn Marian, Rabizadeh Shervin, Rosh Joel R, Snapper Scott, Walters Thomas D, Ziring David, Mondal Kajari, Kappelman Michael D, Hyams Jeffrey S, Kugathasan Subra: Variation in Care in the Management of Children With Crohn's Disease: Data From a Multicenter Inception Cohort Study. Inflammatory bowel diseases Jan 2019.

Church Peter C, Kuint Ruth Cytter, Ledder Oren, Navas-López Victor M, Sladek Malgorzata, Brückner Annecarin, Baldassano Robert N, Weiss Batia, Yerushalmi Baruch, Saeed Shehzad A, Hyams Jeffrey, Otley Anthony, Griffiths Anne M, Turner Dan, Greer Mary-Louise C: Magnetic Resonance Enterography Cannot Replace Upper Endoscopy in Pediatric Crohn's Disease: An ImageKids Sub-study. Journal of pediatric gastroenterology and nutrition 67(1): 53-58, Jul 2018.

Conrad MA, Kelsen JR.: Genomic and Immunologic Drivers of Very Early-Onset Inflammatory Bowel Disease. Pediatr Dev Patho May 2019

Denson Lee A, Jurickova Ingrid, Karns Rebekah, Shaw Kelly A, Cutler David J, Okou David, Alexander Valencia C, Dodd Anne, Mondal Kajari, Aronow Bruce J, Haberman Yael, Linn Aaron, Price Adam, Bezold Ramona, Lake Kathleen, Jackson Kimberly, Walters Thomas D, Griffiths Anne, Baldassano Robert N, Noe Joshua D, Hyams Jeffrey S, Crandall Wallace V, Kirschner Barbara S, Heyman Melvin B, Snapper Scott, Guthery Stephen L, Dubinsky Marla C, Leleiko Neal S, Otley Anthony R, Xavier Ramnik J, Stevens Christine, Daly Mark J, Zwick Michael E, Kugathasan Subra: Genetic and Transcriptomic Variation Linked to Neutrophil Granulocyte-Macrophage Colony-Stimulating Factor Signaling in Pediatric Crohn's Disease. Inflammatory bowel diseases Aug 2018 Notes: doi: 10.1093/ibd/izy265 [Epub ahead of print]

Fernandez IZ, Baxter RM, Garcia-Perez JE, Vendrame E, Ranganath T, Kong DS, Lundquist K, Nguyen T, Ogolla S, Black J, Galambos C, Gumbart JC, Dawany N, Kelsen JR, de Zoeten EF, Quinones R, Eissa H, Verneris MR, Sullivan KE, Rochford R, Blish CA, Kedl RM, Dutmer CM, Hsieh EWY.: A novel human IL2RB mutation results in T and NK cell-driven immune dysregulation. J Exp Med April 2019

Grossman AB (reviewer/contributor): Pediatric Crohn's Disease. National Organization for Rare Disorders (https://rarediseases.org/rare-diseases/pediatric-crohns-disease ) 2019

Haberman Yael, Karns Rebekah, Dexheimer Phillip J, Schirmer Melanie, Somekh Judith, Jurickova Ingrid, Braun Tzipi, Novak Elizabeth, Bauman Laura, Collins Margaret H, Mo Angela, Rosen Michael J, Bonkowski Erin, Gotman Nathan, Marquis Alison, Nistel Mason, Rufo Paul A, Baker Susan S, Sauer Cary G, Markowitz James, Pfefferkorn Marian D, Rosh Joel R, Boyle Brendan M, Mack David R, Baldassano Robert N, Shah Sapana, Leleiko Neal S, Heyman Melvin B, Grifiths Anne M, Patel Ashish S, Noe Joshua D, Aronow Bruce J, Kugathasan Subra, Walters Thomas D, Gibson Greg, Thomas Sonia Davis, Mollen Kevin, Shen-Orr Shai, Huttenhower Curtis, Xavier Ramnik J, Hyams Jeffrey S, Denson Lee A: Ulcerative colitis mucosal transcriptomes reveal mitochondriopathy and personalized mechanisms underlying disease severity and treatment response. Nature communications 10(1): 38, Jan 2019

Haberman Yael, Schirmer Melanie, Dexheimer Phillip J, Karns Rebekah, Braun Tzipi, Kim Mi-Ok, Walters Thomas D, Baldassano Robert N, Noe Joshua D, Rosh Joel, Markowitz James, Crandall Wallace V, Mack David R, Griffiths Anne M, Heyman Melvin B, Baker Susan S, Kellermayer Richard, Moulton Dedrick, Patel Ashish S, Gulati Ajay S, Steiner Steven J, LeLeiko Neal, Otley Anthony, Oliva-Hemker Maria, Ziring David, Kirschner Barbara S, Keljo David J, Guthery Stephen L, Cohen Stanley A, Snapper Scott, Evans Jonathan, Dubinsky Marla, Aronow Bruce, Hyams Jeffrey S, Kugathasan Subra, Huttenhower Curtis, Xavier Ramnik J, Denson Lee A: Age-of-diagnosis dependent ileal immune intensification and reduced alpha-defensin in older versus younger pediatric Crohn Disease patients despite already established dysbiosis. Mucosal immunology Dec 2018.

Hyams Jeffrey S, Davis Thomas Sonia, Gotman Nathan, Haberman Yael, Karns Rebekah, Schirmer Melanie, Mo Angela, Mack David R, Boyle Brendan, Griffiths Anne M, LeLeiko Neal S, Sauer Cary G, Keljo David J, Markowitz James, Baker Susan S, Rosh Joel, Baldassano Robert N, Patel Ashish, Pfefferkorn Marian, Otley Anthony, Heyman Melvin, Noe Joshua, Oliva-Hemker Maria, Rufo Paul A, Strople Jennifer, Ziring David, Guthery Stephen L, Sudel Boris, Benkov Keith, Wali Prateek, Moulton Dedrick, Evans Jonathan, Kappelman Michael D, Marquis M Alison, Sylvester Francisco A, Collins Margaret H, Venkateswaran Suresh, Dubinsky Marla, Tangpricha Vin, Spada Krista L, Saul Bradley, Wang Jessie, Serrano Jose, Hommel Kevin, Marigorta Urko M, Gibson Greg, Xavier Ramnik J, Kugathasan Subra, Walters Thomas, Denson Lee A: Clinical and biological predictors of response to standardised paediatric colitis therapy (PROTECT): a multicentre inception cohort study. Lancet (London, England) Mar 2019.

Kelly Daniel, Kotliar Michael, Woo Vivienne, Jagannathan Sajjeev, Whitt Jordan, Moncivaiz Jessica, Aronow Bruce J, Dubinsky Marla C, Hyams Jeffrey S, Markowitz James F, Baldassano Robert N, Stephens Michael C, Walters Thomas D, Kugathasan Subra, Haberman Yael, Sundaram Nambirajan, Rosen Michael J, Helmrath Michael, Karns Rebekah, Barski Artem, Denson Lee A, Alenghat Theresa: Microbiota-sensitive epigenetic signature predicts inflammation in Crohn's disease. JCI insight 3(18), Sep 2018.

Kelsen JR, Russo P, Sullivan KE.: Early-Onset Inflammatory Bowel Disease. Immunol Allergy Clin North Am Feb 2019

Lekbua A, Ouahed J, O'Connell AE, Kahn SA, Goldsmith JD, Imamura T, Duncan CN, Kelsen JR, Worthey E, Snapper SB, Softic S.: Risk-factors Associated with Poor Outcomes in VEO-IBD Secondary to XIAP Deficiency: A Case Report and Literature Review. JPGN Feb 2019

Lindoso Livia, Mondal Kajari, Venkateswaran Suresh, Somineni Hari K, Ballengee Cortney, Walters Thomas D, Griffiths Anne, Noe Joshua D, Crandall Wallace, Snapper Scott, Rabizadeh Shervin, Rosh Joel R, LeLeiko Neal, Guthery Stephen, Mack David, Kellermayer Richard, Gulati Ajay S, Pfefferkorn Marian D, Moulton Dedrick E, Keljo David, Cohen Stanley, Oliva-Hemker Maria, Heyman Melvin B, Otley Anthony, Baker Susan S, Evans Jonathan S, Kirschner Barbara S, Patel Ashish S, Ziring David, Stephens Michael C, Baldassano Robert, Dubinsky Marla C, Markowitz James, Denson Lee A, Hyams Jeffrey, Kugathasan Subra, Ananthakrishnan Ashwin N: The Effect of Early-Life Environmental Exposures on Disease Phenotype and Clinical Course of Crohn's Disease in Children. The American journal of gastroenterology Sep 2018

Patel T, Conrad M, Kelsen JR: Common Threads in Pediatric Inflammatory Diseases: Insight Into Personalized Medicine. JAMA Pediatrics August 2018.

Priya Chatterji, Patrick A. Williams, Kelly A. Whelan, Fernando C. Samper, Sarah F. Andres, Lauren A. Simon, Louis R Parham, Rei Mizuno, Emma T. Lundsmith, David S.M. Lee, Shun Liang, H.R. Sagara Wijeratne; Stefanie Marti, Lillian Chau, Veronique Giroux, Benjamin J. Wilkins, Gary D. Wu, Premal Shah, Gian G. Tartaglia, and Kathryn E. Hamilton: Posttranscriptional regulation of colonic epithelial repair by RNA binding protein IMP1/IGF2BP1. EMBO Reports March 2019

Schirmer Melanie, Denson Lee, Vlamakis Hera, Franzosa Eric A, Thomas Sonia, Gotman Nathan M, Rufo Paul, Baker Susan S, Sauer Cary, Markowitz James, Pfefferkorn Marian, Oliva-Hemker Maria, Rosh Joel, Otley Anthony, Boyle Brendan, Mack David, Baldassano Robert, Keljo David, LeLeiko Neal, Heyman Melvin, Griffiths Anne, Patel Ashish S, Noe Joshua, Kugathasan Subra, Walters Thomas, Huttenhower Curtis, Hyams Jeffrey, Xavier Ramnik J: Compositional and Temporal Changes in the Gut Microbiome of Pediatric Ulcerative Colitis Patients Are Linked to Disease Course. Cell host & microbe 24(4): 600-610.e4, Oct 2018

Somineni Hari K, Venkateswaran Suresh, Kilaru Varun, Marigorta Urko M, Mo Angela, Okou David T, Kellermayer Richard, Mondal Kajari, Cobb Dawayland, Walters Thomas D, Griffiths Anne, Noe Joshua D, Crandall Wallace V, Rosh Joel R, Mack David R, Heyman Melvin B, Baker Susan S, Stephens Michael C, Baldassano Robert N, Markowitz James F, Dubinsky Marla C, Cho Judy, Hyams Jeffrey S, Denson Lee A, Gibson Greg, Cutler David J, Conneely Karen N, Smith Alicia K, Kugathasan Subra: Blood-derived DNA Methylation Signatures of Crohn's Disease and Severity of Intestinal Inflammation. Gastroenterology Feb 2019.

Sullivan Ke, Conrad M, Kelsen JR: Very early-onset inflammatory bowel disease: an integrated approach. Curr Opin Allergy Clin Immuno 18, Dec 2018

Tokarz Rafal, Hyams Jeffrey S, Mack David R, Boyle Brendan, Griffiths Anne M, LeLeiko Neal S, Sauer Cary G, Shah Sapana, Markowitz James, Baker Susan S, Rosh Joel, Baldassano Robert N, Kugathasan Subra, Walters Thomas, Tagliafierro Teresa, Sameroff Stephen, Lee Bohyun, Che Xiaoyu, Oleynik Alexandra, Denson Lee A, Lipkin W Ian: Characterization of Stool Virome in Children Newly Diagnosed With Moderate to Severe Ulcerative Colitis. Inflammatory bowel diseases May 2019.

Trusha Patel MD, Rawan Shraim BS, Kelly Maurer BA, Noor Dawany PhD, Claudio C. Giraudo PhD, Maire Conrad MD, Kathleen E. Sullivan MD, PhD and Judith R. Kelsen MD: Immunophenotyping of Very Early Onset Inflammatory Bowel Disease Patients: Population-Level Analysis NASPGHAN 2018

Turner Dan, Griffiths Anne M, Wilson David, Mould Diane R, Baldassano Robert N, Russell Richard K, Dubinsky Marla, Heyman Melvin B, de Ridder Lissy, Hyams Jeffrey, Martin de Carpi Javier, Conklin Laurie, Faubion William A, Koletzko Sibylle, Bousvaros Athos, Ruemmele Frank M: Designing clinical trials in paediatric inflammatory bowel diseases: a PIBDnet commentary. Gut Apr 2019.

Wu Jing, Lubman David M, Kugathasan Subra, Denson Lee A, Hyams Jeffrey S, Dubinsky Marla C, Griffiths Anne M, Baldassano Robert N, Noe Joshua D, Rabizadeh Shervin, Gulati Ajay S, Rosh Joel R, Crandall Wallace V, Higgins Peter D R, Stidham Ryan W: Serum Protein Biomarkers of Fibrosis Aid in Risk Stratification of Future Stricturing Complications in Pediatric Crohn's Disease. The American journal of gastroenterology 114(5): 777-785, May 2019

Zhou Lei, Chu Coco, Teng Fei, Bessman Nicholas J, Goc Jeremy, Santosa Endi K, Putzel Gregory G, Kabata Hiroki, Kelsen Judith R, Baldassano Robert N, Shah Manish A, Sockolow Robbyn E, Vivier Eric, Eberl Gérard, Smith Kendall A, Sonnenberg Gregory F: Innate lymphoid cells support regulatory T cells in the intestine through interleukin-2. Nature Apr 2019.

Bertha Madeline, Vasantharoopan Arthi, Kumar Archana, Bruce Beau B, Prince Jarod, Hofmekler Tatyana, Okou David, Chopra Pankaj, Wang Gabriel, Sauer Cary, Landers Carol J, Hussain Sunny Z, Cross Raymond K, Baldassano Robert N, Kappelman Michael D, Katz Jeffrey, Alexander Jonathan S, Kirschner Barbara S, Moulton Dedrick E, Osuntokun Bankole O, Patel Ashish, Saeed Shehzad, Klapproth Jan-Michael A, Dhere Tanvi A, Dubinsky Marla C, McGovern Dermot, Kugathasan Subra: IBD Serology and Disease Outcomes in African Americans With Crohn's Disease. Inflammatory bowel diseases 24(1): 209-216, Dec 2017.

Boyle Brendan, Collins Margaret H, Wang Zhu, Mack David, Griffiths Anne, Sauer Cary, Markowitz James, LeLeiko Neal, Keljo David, Rosh Joel, Baker Susan S, Pfefferkorn Marian, Heyman Melvin, Patel Ashish, Baldassano Robert, Noe Joshua, Rufo Paul, Kugathasan Subra, Walters Thomas, Denson Lee, Hyams Jeffrey: Histologic Correlates of Clinical and Endoscopic Severity in Children Newly Diagnosed With Ulcerative Colitis. The American Journal of Surgical Pathology 41(11): 1491-1498, Nov 2017.

Canna SW, Girard C, Malle L, de Jesus A, Romberg N, Kelsen J, Surrey LF, Russo P, Sleight A, Schiffrin E, Gabay C, Goldbach-Mansky R, Behrens EM: Life-threatening NLRC4-associated hyperinflammation successfully treated with IL-18 inhibition. J. Allergy Clin Immunol. 139(5): 1698-1701, May 2017.

Conrad MA, Dawany N, Sullivan KE, Devoto M, Kelsen JR: Novel ZBTB24 mutation associated with immunodeficiency, centromere instability, and facial anomalies type 2 syndrome identified in a patient with very early onset inflammatory bowel disease. Inflammatory Bowel Diseases 23(12): 2252-2255, Dec 2017.

Hyams Jeffrey S, Davis Sonia, Mack David R, Boyle Brendan, Griffiths Anne M, LeLeiko Neal S, Sauer Cary G, Keljo David J, Markowitz James, Baker Susan S, Rosh Joel, Baldassano Robert N, Patel Ashish, Pfefferkorn Marian, Otley Anthony, Heyman Melvin, Noe Joshua, Oliva-Hemker Maria, Rufo Paul, Strople Jennifer, Ziring David, Guthery Stephen L, Sudel Boris, Benkov Keith, Wali Prateek, Moulton Dedrick, Evans Jonathan, Kappelman Michael D, Marquis Alison, Sylvester Francisco A, Collins Margaret H, Venkateswaran Suresh, Dubinsky Marla, Tangpricha Vin, Spada Krista L, Britt Ashley, Saul Bradley, Gotman Nathan, Wang Jessie, Serrano Jose, Kugathasan Subra, Walters Thomas, Denson Lee A: Factors associated with early outcomes following standardised therapy in children with ulcerative colitis (PROTECT): a multicentre inception cohort study. Lancet Gastroenterology & hepatology 2(12): 855-868, Dec 2017.

Hyams Jeffrey S, Dubinsky Marla C, Baldassano Robert N, Colletti Richard B, Cucchiara Salvatore, Escher Johanna, Faubion William, Fell John, Gold Benjamin D, Griffiths Anne, Koletzko Sibylle, Kugathasan Subra, Markowitz James, Ruemmele Frank M, Veereman Gigi, Winter Harland, Masel Nicholas, Shin Chu Ri, Tang Kezhen L, Thayu Meena: Infliximab is not Associated With Increased Risk of Malignancy or Hemophagocytic Lymphohistiocytosis in Pediatric Patients With Inflammatory Bowel Disease.Gastroenterology 152(8): 1901-1914.e3, Feb 2017.

Kugathasan Subra, Denson Lee A, Walters Thomas D, Kim Mi-Ok, Marigorta Urko M, Schirmer Melanie, Mondal Kajari, Liu Chunyan, Griffiths Anne, Noe Joshua D, Crandall Wallace V, Snapper Scott, Rabizadeh Shervin, Rosh Joel R, Shapiro Jason M, Guthery Stephen, Mack David R, Kellermayer Richard, Kappelman Michael D, Steiner Steven, Moulton Dedrick E, Keljo David, Cohen Stanley, Oliva-Hemker Maria, Heyman Melvin B, Otley Anthony R, Baker Susan S, Evans Jonathan S, Kirschner Barbara S, Patel Ashish S, Ziring David, Trapnell Bruce C, Sylvester Francisco A, Stephens Michael C, Baldassano Robert N, Markowitz James F, Cho Judy, Xavier Ramnik J, Huttenhower Curtis, Aronow Bruce J, Gibson Greg, Hyams Jeffrey S, Dubinsky Marla C: Prediction of complicated disease course for children newly diagnosed with Crohn's disease: a multicentre inception cohort study. Lancet (London, England) 389(10080): 1710-1718, Apr 2017.

Marigorta Urko M, Denson Lee A, Hyams Jeffrey S, Mondal Kajari, Prince Jarod, Walters Thomas D, Griffiths Anne, Noe Joshua D, Crandall Wallace V, Rosh Joel R, Mack David R, Kellermayer Richard, Heyman Melvin B, Baker Susan S, Stephens Michael C, Baldassano Robert N, Markowitz James F, Kim Mi-Ok, Dubinsky Marla C, Cho Judy, Aronow Bruce J, Kugathasan Subra, Gibson Greg: Transcriptional risk scores link GWAS to eQTLs and predict complications in Crohn's disease. Nature genetics 49(10): 1517-1521, Oct 2017.

Maxwell EC, Dawany N, Baldassano RN, Mamula P, Mattei P, Albenberg L, Kelsen JR: Diverting ileostomy for the treatment of severe, refractory, pediatric inflammatory bowel disease. JPGN 65(3): 299-305, September 2017.

Ni Josephine, Shen Ting-Chin David, Chen Eric Z, Bittinger Kyle, Bailey Aubrey, Roggiani Manuela, Sirota-Madi Alexandra, Friedman Elliot S, Chau Lillian, Lin Andrew, Nissim Ilana, Scott Justin, Lauder Abigail, Hoffmann Christopher, Rivas Gloriany, Albenberg Lindsey, Baldassano Robert N, Braun Jonathan, Xavier Ramnik J, Clish Clary B, Yudkoff Marc, Li Hongzhe, Goulian Mark, Bushman Frederic D, Lewis James D, Wu Gary D: A role for bacterial urease in gut dysbiosis and Crohn's disease. Science translational medicine 9(416), Nov 2017.

Walters Thomas D, Faubion William A, Griffiths Anne M, Baldassano Robert N, Escher Johanna, Ruemmele Frank M, Hyams Jeffrey S, Lazar Andreas, Eichner Samantha, Huang Bidan, Li Yao, Thakkar Roopal B: Growth Improvement with Adalimumab Treatment in Children with Moderately to Severely Active Crohn's Disease. Inflammatory bowel diseases 23(6): 967-975, Jun 2017.

Picoraro J, Winberry G, Siegel C, El-Matary W, Moses J, Grossman AB, Park KT: Premedication Use Prior to Infliximab Administration: A Cross-Sectional Analysis from the Clinical Care and Quality and Inflammatory Bowel Disease Committees of NASPGHAN. World Congress of Pediatric Gastroenterology, Hepatology, and Nutrition, Montreal, Quebec October 2016.

Kerur B, Machan JT, Cerezo C, Markowitz J, Mack DR, Griffiths AM, Otley AR, Pfefferkorn MD, Rosh JR, Keljo DJ, Crandall WV, Rick J, Noe J, Oliva-Hemker M, Kay MH, Saeed SA, Grossman AB, Sudel B, Kappelman M, Schaefer M, Faubion W, Tomer G, Deslandres C, Morganstern J, Bousvaros A, Lerer T, Hyams JS, LeLeiko NS: Surgery in Pediatric Crohn's Disease 2002-2014. World Congress of Pediatric Gastroenterology, Hepatology, and Nutrition, Montreal, Quebec October 2016.

Kelsen J, Dawany N, Conrad M, Piccoli D, Giraudo C, Behrens E, Sullivan K, Devoto M: "The role of the Hyperinflammatory Pathway in Very Early-Onset Inflammatory Bowel Disease. Poster Presentation at the World Congress of Pediatric Gastroenterology, Hepatology and Nutrition Meeting, Montreal, Canada October 2016.

Itkin M, Piccoli DA, Dori Y: "Protein-Losing Enteropathy: Redefining the Anatomy and Pathophysiology and Providing Novel Therapy" Poster Presentation at the World Congress of Pediatric Gastroenterology, Hepatology and Nutrition Meeting, Montreal, Canada October 2016.

El-Matary W, Samson C, Ali S, Grossman AB: Rapid Infliximab Infusion in Children with Inflammatory Bowel Disease: A Multi-Center North American Experience. World Congress of Pediatric Gastroenterology, Hepatology, and Nutrition, Montreal, Quebec October 2016.

Conrad M, Darwany N, Bittinger K, Baldassano RN, Piccoli DA, Bushman F, Devoto M, Kelsen J: "Characterization of the Intestinal Microbiome of Very Early Onset Inflammatory Bowel Disease" Poster Presentation at the World Congress of Pediatric Gastroenterology, Hepatology and Nutrition Meeting, Montreal, Canada October 2016.

Conrad MA, Dawany N, Bittinger K, Baldassano RN, Piccoli D, Bushman FD, Devoto M, Kelsen JR: Characterization of the Intestinal Microbiome in Very Early Onset Inflammatory Bowel Disease Digestive Disease Week Annual Meeting, San Diego, CA May 2016.

Kelsen JR, Dawany N, Conrad, MA, Martinez A, Artis D, Sonnenberg GF, Mamula P, Piccoli DA, Baldassano RN, Sullivan KE, Devoto M: SU1851 Transcriptome Analysis Elucidates the Relevance of WES-Identified Variants in Patients with VEO-IBD. Gastroenterology 150(4): S570, April 2016.

Crawford JE.; Stevenson J.; Goldoor L.; Markowitz L.; Tucker M.; Novelli C.; Turner E.; Bogan G.; Driggers J.; Peck S.; Grossman AB.: The Multidisciplinary Inflammatory Bowel Disease (IBD) Education Model: An educational approach that crosses developmental and life stages of children & families living with IBD. National Association of Clinical Nurse Specialists Annual Meeting, Philadelphia, PA March 2016.

Plantz K, Stein R, Maxwell E, Mamula P, Baldassano RN. Intravenous iron sucrose for treatment of iron deficiency anemia in pediatric inflammatory bowel disease. 2015 Advances in Inflammatory Bowel Diseases: Crohn’s & Colitis Foundation’s Clinical & Research Conference, Orlando FL, Dec 10-12, 2015; Inflamm Bowel Dis 22(S1):S1-S91, March 2016. Oral and poster presentation. Additional poster presentation at the 2016 Children’s Hospital of Philadelphia Research Poster Day, Feb 24, 2016, was presented the “Patient-Oriented Research Award”.

Kelsen J, Dawany N, Conrad M, Martinez A, Mamula P, Piccoli D, Artis D, Sonnenberg G, Baldassano RN, Sullivan K, Devoto M. Understanding the relevance of whole exome sequencing identified variants in patients with very early-onset-IBD. 2015 Advances in Inflammatory Bowel Diseases: Crohn’s & Colitis Foundation’s Clinical & Research Conference, Orlando FL, Dec 10-12, 2015; Inflamm Bowel Dis 22(S1):S1-S91, March 2016.

Zeisler B, Lerer T, LeLeiko N, Bousvaros A, Rosh J, Grossman AB, Kay M, Faubion W, Kappelman M, Markowitz J, Sudel B, Rick J, Cabrera J, Boyle B, Oliva-Hemker M, Pfefferkorn M, Morganstern J, Saeed S, Otley A, Keljo D, Griffiths A, Mack D, Hyams J: Outcome Following Aminosalicylate Therapy in Children Newly Diagnosed with Crohn's Disease: A Prospective Multi-center Registry Experience. North American Society for Pediatric Gastroenterology, Hepatology, and Nutrition Annual Meeting, Washington, DC October 2015.

Stein RE, Conrad MA, Maxwell EC, Albenberg LA, Baldassano RN, Dawany N, Grossman AB, Mamula P, Piccoli DA, Kelsen JR: Vedolizumab Therapy in Severe Pediatric Inflammatory Bowel Disease. North American Society for Pediatric Gastroenterology, Hepatology, and Nutrition Annual Meeting, Washington, DC October 2015.

Hoffman NJ, Maxwell EC, Piccoli DA, Grossman AB: ESR and CRP in Inflammatory Bowel Disease: Do We Need Both? North American Society for Pediatric Gastroenterology, Hepatology, and Nutrition Annual Meeting, Washington, DC October 2015.

Godwin B, Demuynck S, Maxwell E, Baldassano RN, Grossman AB, Kelsen JR, Albenberg L: Efficacy of Combination Antibiotic Therapy for Refractory IBD at CHOP: A Single Center Case Series. North American Society for Pediatric Gastroenterology, Hepatology, and Nutrition Annual Meeting, Washington, DC October 2015.

Adler J, Grossman AB, Israel EJ, Kim S, Saeed SA, Pratt JM, Collins J, Colletti R: Extent of Disease in Ulcerative Colitis in a Pediatric Inflammatory Bowel Disease Learning Health Network. North American Society for Pediatric Gastroenterology, Hepatology, and Nutrition Annual Meeting, Washington, DC October 2015.

Yaeger R, Miller V, Kelsen JR, Wang K, Tang L, Kelsen D: Clinically relevant genomic alterations are frequent in Colitis Associated Cancers. ASCO May 2015.

Kelsen J, Albenberg L, Bailey A, Bittinger K, Schall1 J, Mascarenhas M, Bushman FD, and Stallings G: 16S Gene Sequencing Reveals a Unique Bacterial Signature in the Gut Microbiota of Pediatric Patients with Cystic Fibrosis. Digestive Disease Week May 2015.

Kelsen J Dawany, N, Moran C, Winter D, Daly M, Rappaport E, Mamula P, Piccoli P, Artis D, Sonnenberg G, Baldassano R, Sullivan K, Devoto, M: Autosomal recessive model of transmission in VEO-IBD using WES. Oral Abstract DDW May 2015.

Conrad M, Stein R, Maxwell EC, Albenberg L, Baldassano R, Grossman AB, Mamula P, Piccoli D, Delsen JR: The Use of Vedolizumab for Treatment of Severe Pediatric Inflammatory Bowel Disease. Digestive Disease Week, Washington, DC May 2015 Notes: Oral presentation by collaborator Stein R.

Kelsen J, Moran C, Noor D, Pauly-Hubbard H, Rappaport E, Mamula P, Piccoli DA, Winter H, Daly M, Sonnenberg G, Artis D, Baldassano RN, Marcella D. Digenic inheritance of primary immunodeficiency gene variants identified by whole exome sequence in very early onset IBD patients. 2014 Advances in Inflammatory Bowel Diseases: Crohn’s & Colitis Foundation’s Clinical & Research Conference, Orlando FL, Dec 4-6, 2014; Inflamm Bowel Dis 20():S9-S10, Dec 2014. Oral presentation.

Kelsen J Dawany, N, Moran C, Winter D, Daly M, Rappaport E, Mamula P, Piccoli P, Artis D, Sonnenberg G, Baldassano R, Sullivan K, Devoto, M: Digenic inheritance of primary immunodeficiency gene variants identified by whole exome sequence in VEO-IBD patients. Oral Abstract CCFA Dec 2014.

Cardinale C, Li J, Wei Z, Chang X, Baldassano RN, Hakonarson H. Pathway-based genome-wide association study reveals an association between ErbB signaling and inflammatory bowel disease. 2014 Advances in Inflammatory Bowel Diseases: Crohn’s & Colitis Foundation’s Clinical & Research Conference, Orlando FL, Dec 4-6, 2014;

Turner D, Doveh E, Cohen A, Wilson D, Grossman AB, Rosh J, Lu T, Noble A, Baldassano RN, Levine A, Lerner A, Bousvaros A, Griffiths AM: Oral versus subcutaneous methotrexate in pediatric Crohn's disease: a multicenter propensity score study. UEG Week, Vienna, Austria October 2014.

Sahn B, De Matos, V, Ruchelli E, Masur S, Klink A, Baldassano RN, Piccoli, DA, Russo P, Mamula P. A histological scoring system for ileitis in children with inflammatory bowel disease. North American Society for Pediatric Gastroenterology, Hepatology and Nutrition (NASPGHAN) 2014 Annual Meeting, Atlanta GA, Oct 23-26, 2014; JPGN:59(S2),S34. Poster presentation.

Morganstern J, Lapsia S, Lerer T, Markowitz J, Griffiths A, Cabrera J, Mack D, Rick JR, Otley A, Pfefferkorn M, Rosh J, Kay M, Oliva-Hemker M, Saeed S, LeLeiko N, Carvalho R, Grossman AB, Keljo D, Sudel B, Kappelman M, Faubion W, Kugathasan S, Schaefer M, Tomer G, Deslandres C: Association of Being Overweight or Obese on Hospitalization, Surgeries, and Escalation of Medical Therapy in Inflammatory Bowel Disease. North American Society for Pediatric Gastroenterology, Hepatology, and Nutrition Annual Meeting, Atlanta, GA October 2014.

Maxwell E, Kelsen J: Sickle Cell Disease in Pediatric Patients with Inflammatory Bowel Disease: A case Series of Six Patients. NASPGHAN Annual Meeting, Poster Presentation, Atlanta, GA October 2014.

Lee R, Lerer T, Griffiths A, Pfefferkorn M, Otley A, Rick J, Mack D, Cabrera J, Rosh J, Bousvaros A, Kay M, Oliva-Hemker M, Saeed S, LeLeiko N, Grossman AB, Keljo D, Kappelman M, Faubion W, Deslandres C, Boyle B, Markowitz J, Hyams J: Durability of Adalimumab Therapy in Children with Crohn's Disease. North American Society for Pediatric Gastroenterology, Hepatology, and Nutrition Annual Meeting, Atlanta, GA October 2014.

Lee D, Baldassano RN, Compher C, Albenberg L, Otley A, Griffiths A, Bushman F, Wu GD, Lewis JD. Effectiveness of nutritional and anti-TNF therapy in North American children with active Crohn’s disease. North American Society for Pediatric Gastroenterology, Hepatology and Nutrition (NASPGHAN) 2014 Annual Meeting, Atlanta GA, Oct 23-26, 2014; JPGN:59(S2),S37. Poster presentation.

Kelsen J, Moran C, Sasson A, Pauly-Hubbard H, Rappaport E, Mamula P, Piccoli D, Artis D, Sonnenberg G, Winter H, Baldassano RN, Devoto M. Analysis of candidate genes by whole exome sequencing in very early-onset IBD. North American Society for Pediatric Gastroenterology, Hepatology and Nutrition (NASPGHAN) 2014 Annual Meeting, Atlanta GA, Oct 23-26, 2014; JPGN:59(S2),S147. Poster presentation. NASPGHAN Young Investigator Award.

Kelsen J, Dawany N, Moran C, Rappaport E, Winter H, Daly M, Mamula P, Piccoli P, Artis D, Sonnenberg G, Baldassano R, Sullivan K, Devoto M: Analysis of Candidate Genes in_ VEO-IBD. Oral Abstract, NASPGHAN 2014 Oct 2014.

Walters T, Faubion WA, Griffths A, Baldassano RN, Escher J, Ruemmele F, Hyams JS, Lazar A, Eichner S, Li Y, Pappalardo B, Thakkar RB. Growth improvement in adalimumab-treated paediatric patients with Crohn’s disease: Data from Imagine 1. 3rd International Symposium on Pediatric Inflammatory Bowel Disease (PIBD 2014), Rotterdam, The Netherlands, Sept 10-13, 2014. Poster presentation.

Stein RE, Lee DY, Leonard MB, Thayu M, Herskovitz RM, Kerbowski T, Baldassano RN. The association between drug levels, anti-drug antibodies, and therapeutic response during infliximab therapy in pediatric Crohn disease. 3rd International Symposium on Pediatric Inflammatory Bowel Disease (PIBD 2014), Rotterdam, The Netherlands, Sept 10-13, 2014. Poster presentation.

Otley R, Lee DY, Baldassano RN, Griffths AM, Compher CW, Albenberg LG, Bushman FD, Wu GD, Lewis JD. Comparison of quality of life among children treated with nutritional and anti-TNF therapies for active Crohn’s disease in North America. 3rd International Symposium on Pediatric Inflammatory Bowel Disease (PIBD 2014), Rotterdam, The Netherlands, Sept 10-13, 2014. Poster presentation.

Lee DY, Baldassano RN, Compher CW, Albenberg LG, Otley AR, Griffths AM, Bushman FD, Wu GD, Lewis JD. Effectiveness of nutritional and anti-TNF therapy in North American children with active Crohn’s disease. 3rd International Symposium on Pediatric Inflammatory Bowel Disease (PIBD 2014), Rotterdam, The Netherlands, Sept 10-13, 2014. Oral presentation – accepted for Best Abstract.

Markowitz J, Lerer T, Morganstern J, Deslandres C, Tomer G, Schaefer M, Kugathasan S, Faubion WA, Kappelman M, Sudel B, Hitch M, Keljo DJ, Grossman AB, Carvalho R, Leleiko NS, Saeed SA, Oliva-Hemker M, Kay MH, Rosh JR, Pfefferkorn MD, Otley AR, Rick J, Mack DR, Cabrera J, Griffiths AM, Hyams JS: Long-term Outcome of Children With Crohn's Disease: Results from a Large Multi-center North American Inception Cohort. Digestive Disease Week, American Gastroenterological Association Annual Meeting, Chicago, IL May 2014.

Lindsey G. Albenberg, Christel Chehoud, Colleen Judge, Christian Hoffman, Stephanie Grunberg, Kyle Bittinger, Robert N. Baldassano, James D. Lewis, Frederic D. Bushman, and Gary D. Wu: Gene Sequencing Reveals a Unique Fungal Signature in the Gut Microbiota of Pediatric Patients with Inflammatory Bowel Disease. Poster Presentation. Digestive Disease Week May 2014.

Lindsey Albenberg*, Tatiana Esipova*, Colleen Judge, Kyle Bittinger, Jun Chen, Stephanie Grunberg, Robert Baldassano, James D. Lewis, Hongzhe Li, Frederic D. Bushman, Sergei Vinogradov, Gary D. Wu: Radial Partitioning of the Gut Microbiota Associated with Tolerance to Oxygen and Assacharolytic Metabolism. Poster Presentation. Digestive Disease Week May 2014.

Kelsen JR, Moran CJ, Sasson A, Sarmady M, Gupta K, Pauly-Hubbard H, Rappaport E, Stolle C, Mamula P, Grossman AB, Piccoli D, Winter H, Baldassano R, Devoto M: Exome Sequencing Analysis of Candidate Genes in Very Early Onset IBD. Digestive Disease Week, American Gastroenterological Association Annual Meeting, Chicago, IL May 2014.

Jump C, Sahn B, Wendel D, Muir AB, Fish S, Augustine M, Ballantine A, Lin HC, Albenberg L: Teaching Residents GI in a "Flipped Classroom" on an Inpatient Pediatric Gastroenterology Rotation. Poster Presentation. Digestive Disease Week May 2014.

Grossi V, Lerer T, Leleiko NS, Mack DR, Griffiths AM, Otley AR, Pfefferkorn MD, Rosh JR, Oliva-Hemker M, Saeed SA, Grossman AB, Keljo D, Sudel1 B, Kappelman M, Faubion WA, Schaefer M, Tomer G, Deslandres C, Cabrera1 J, Carvalho R, Hitch M, Morganstern J, Kay MH, Rick J, Markowitz J, Hyams JS: Durability of Maintenance Infliximab Therapy in Children with Crohn's Disease: Are gender and concomitant immunomodulators more important than we thought? Digestive Disease Week, American Gastroenterological Association Annual Meeting, Chicago, IL May 2014.

Cardinale CJ, Kelsen JR, Baldassano RN, & Hakonarson, H. (2013). Impact of exome sequencing in inflammatory bowel disease. World Journal of Gastroenterology: WJG, 19(40), 6721. Read abstract.

Cardinale CJ, Wei Z, Panossian S, Wang F, Kim CE, Mentch FD, Chiavacci RM, Kachelries KE, Pandey R, Grant SF, Baldassano RN, Hakonarson H. (2013). Targeted resequencing identifies defective variants of decoy receptor 3 in pediatric-onset inflammatory bowel disease. Genes and immunity. Read abstract.

Gupta K, Noble A, Kachelries KE, Albenberg L, Kelsen JR, Grossman AB, Baldassano RN. (2013). A novel enteral nutrition protocol for the treatment of pediatric Crohn's disease. Inflammatory Bowel Diseases. [In process] Read abstract.

Tsampalieros A, Lam CK, Spencer JC, Thayu M, Shults J, Zemel BS, Herskovitz RM, Baldassano RN, Leonard MB. (2013). Long term inflammation and glucocorticoid therapy impair skeletal modeling during growth in childhood Crohn's disease. Journal of Clinical Endocrinology & Metabolism. Read abstract.

Walters TD, Kim M, Denson LA, Griffiths AM, Dubinsky M, Markowitz J, Baldassano R, Crandall W, Rosh J, Pfefferkorn M, Otley A, Heyman MB, Leleiko N, Baker S, Guthery SL, Evans J, Ziring D, Kellermayer R, Stephens M, Mack D, Oliva-Hemker M, Patel AS, Kirschner B, Moulton D, Cohen S, Kim S, Liu C, Essers J, Kugathasan S, Hyams JS. (2013). Comparative effectiveness of early therapy with anti-tumor necrosis factor-α vs. an immunomodulator in children With Crohn’s disease. Gastroenterology. Read abstract.

Wei Z, Wang W, Bradfield J, Li J, Cardinale C, Frackelton E, Kim C, Mentch F, Van Steen K, Visscher PM, Baldassano RN, Hakonarson H (2013). Large sample size, wide variant spectrum, and advanced machine-learning technique boost risk prediction for inflammatory bowel disease. The American Journal of Human Genetics. Read abstract.

Zeisler B, Lerer T, Markowitz J, Mack D, Griffiths A, Bousvaros A, ... & Hyams J. (2013). Outcome following aminosalicylate therapy in children newly diagnosed as having ulcerative colitis. Journal of Pediatric Gastroenterology and Nutrition, 56(1), 12-18. Read abstract.

Gray WN, Denson LA, Baldassano RN, & Hommel KA. (2012). Treatment adherence in adolescents with inflammatory bowel disease: the collective impact of barriers to adherence and anxiety/depressive symptoms. Journal of Pediatric Psychology, 37(3), 282-291. Read abstract.

Guilfoyle SM, Denson LA, Baldassano RN, & Hommel KA. (2012). Paediatric parenting stress in inflammatory bowel disease: application of the Pediatric Inventory for Parents. Child: Care, Health and Development, 38(2), 273-279. Read abstract.

Hyams JS, Griffiths A, Markowitz J, Baldassano RN, Faubion WA Jr, Colletti RB, Dubinsky M, Kierkus J, Rosh J, Wang Y, Huang B, Bittle B, Marshall M, Lazar A. (2012). Safety and efficacy of adalimumab for moderate to severe Crohn's disease in children. Gastroenterology, 143(2), 365-374. Read abstract.

Hyams J, Damaraju L, Blank M, Johanns J, Guzzo C, Winter HS, Kugathasan S, Cohen S, Markowitz J, Escher JC, Veereman-Wauters G, Crandall W, Baldassano R, Griffiths A2012). Induction and maintenance therapy with infliximab for children with moderate to severe ulcerative colitis. Clinical Gastroenterology and Hepatology, 10(4), 391-399. Read abstract.

Kelsen, JR, & Wu, GD. (2012). The gut microbiota, environment and diseases of modern society. Gut Microbes, 3(4), 374-382. Read abstract.

Otley A, LeLeiko N, Langton C, Lerer T, Mack D, Evans J, ... & Hyams J. (2012). Budesonide use in pediatric Crohn's disease. Journal of Pediatric Gastroenterology and Nutrition, 55(2), 200-204. Read abstract.

Prosnitz AR, Leonard MB, Shults J, Zemel BS, Hollis BW, Denson LA, Baldassano RN, Cohen AB, Thayu M. (2012). Changes in vitamin D and parathyroid hormone metabolism in incident pediatric Crohn's disease. Inflammatory Bowel Diseases. Read abstract.

Yatsunenko T, Rey FE, Manary MJ, Trehan I, Dominguez-Bello MG, Contreras M, Magris M, Hidalgo G, Baldassano RN, Anokhin AP, Heath AC, Warner B, Reeder J, Kuczynski J, Caporaso JG, Lozupone CA, Lauber C, Clemente JC, Knights D, Knight R, Gordon JI.. (2012). Human gut microbiome viewed across age and geography. Nature, 486(7402), 222-227. Read abstract.

Albenberg LG, Lewis JD, & Wu GD. (2012). Food and the gut microbiota in inflammatory bowel diseases: a critical connection. Current Opinion in Gastroenterology, 28(4), 314-320. Read abstract.

Anderson CA, Boucher G, Lees CW, Franke A, D'Amato M, Taylor KD, ... Baldassano RN,… & Mowat C. (2011). Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47. Nature Genetics, 43(3), 246-252. Read abstract.

Gray WN, Denson LA, Baldassano RN, & Hommel KA. (2011). Disease activity, behavioral dysfunction, and health‐related quality of life in adolescents with inflammatory bowel disease. Inflammatory Bowel Diseases,17(7), 1581-1586. Read abstract.

Herzer M, Denson LA, Baldassano RN, & Hommel KA. (2011). Family functioning and health-related quality of life in adolescents with pediatric inflammatory bowel disease. European Journal of Gastroenterology & Hepatology, 23(1), 95. Read abstract.

Herzer M, Denson LA, Baldassano RN, & Hommel KA. (2011). Patient and parent psychosocial factors associated with health-related quality of life in pediatric inflammatory bowel disease. Journal of Pediatric Gastroenterology and Nutrition, 52(3), 295. Read abstract.

Hommel KA, Denson LA, & Baldassano RN. (2011). Oral medication adherence and disease severity in pediatric inflammatory bowel disease. European Journal of Gastroenterology & Hepatology, 23(3), 250. Read abstract.

Hommel KA, Odell S, Sander E, Baldassano RN, & Barg FK. (2011). Treatment adherence in paediatric inflammatory bowel disease: perceptions from adolescent patients and their families. Health & Social Care in the Community, 19(1), 80-88. Read abstract.

Hyams JS, Lerer T, Mack D, Bousvaros A, Griffiths A, Rosh J, … Grossman A, ... & Markowitz J. (2011). Outcome following thiopurine use in children with ulcerative colitis: a prospective multicenter registry study. The American Journal of Gastroenterology, 106(5), 981-987. Read abstract.

Hyams J, Walters TD, Crandall W, Kugathasan S, Griffiths A, Blank M, ... & Baldassano R. (2011). Safety and efficacy of maintenance infliximab therapy for moderate-to-severe Crohn's disease in children: REACH open-label extension. Current Medical Research & Opinion, 27(3), 651-662. Read abstract.

Kelsen JR, Kim J, Latta D, Smathers S, McGowan KL, Zaoutis T, ... & Baldassano RN. (2011). Recurrence rate of Clostridium difficile infection in hospitalized pediatric patients with inflammatory bowel disease. Inflammatory Bowel Diseases, 17(1), 50-55. Read abstract.

Odell S, Sander E, Denson LA, Baldassano RN, & Hommel KA. (2011). The contributions of child behavioral functioning and parent distress to family functioning in pediatric inflammatory bowel disease. Journal of Clinical Psychology in Medical Settings, 18(1), 39-45. Read abstract.

Turner D, Travis SP, Griffiths AM, Ruemmele FM, Levine A, Benchimol EI, ... Baldassano RN,…& Russell RK. (2011). Consensus for managing acute severe ulcerative colitis in children: a systematic review and joint statement from ECCO, ESPGHAN, and the Porto IBD Working Group of ESPGHAN. The American Journal of Gastroenterology, 106(4), 574-588. Read abstract.

Wu GD, Chen J, Hoffmann C, Bittinger K, Chen YY, Keilbaugh SA, Bewtra M, Knights D, Walters WA, Knight R, Sinha R, Gilroy E, Gupta K, Baldassano R, Nessel L, Li H, Bushman FD, Lewis JD. (2011). Linking long-term dietary patterns with gut microbial enterotypes. Science, 334(6052), 105-108. Read abstract.

Zahm AM, Thayu M, Hand NJ, Horner A, Leonard MB, & Friedman JR. (2011). Circulating microRNA is a biomarker of pediatric Crohn's disease. Journal of Pediatric Gastroenterology and Nutrition, 53(1), 26-33. Read abstract.

Franke A, McGovern DP, Barrett JC, Wang K, Radford-Smith GL, Ahmad T, ... Baldassano RN,… & Van Gossum A. (2010). Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci. Nature genetics, 42(12), 1118-1125. Read abstract.

Gupta N, Bostrom AG, Kirschner BS, Ferry GD, Gold BD, Cohen SA, Winter HS, Baldassano RN, Abramson O, Smith T, Heyman MB. (2010). Incidence of stricturing and penetrating complications of Crohn's disease diagnosed in pediatric patients. Inflammatory Bowel Diseases, 16(4), 638-644. Read abstract.

Hommel KA, & Baldassano RN. (2010). Brief report: Barriers to treatment adherence in pediatric inflammatory bowel disease. Journal of Pediatric Psychology, 35(9), 1005-1010. Read abstract.

Hyams JS, Lerer T, Griffiths A, Pfefferkorn M, Stephens M, Evans J, … Grossman A ... & Markowitz J. (2010). Outcome following infliximab therapy in children with ulcerative colitis. The American Journal of Gastroenterology. Read abstract.

Ingerski LM, Baldassano RN, Denson LA, & Hommel KA. (2010). Barriers to oral medication adherence for adolescents with inflammatory bowel disease. Journal of Pediatric Psychology, 35(6), 683-691. Read abstract.

Kelsen JR, Rosh J, Heyman M, Winter HS, Ferry G, Cohen S, ... & Baldassano RN. (2010). Phase I trial of sargramostim in pediatric Crohn's disease. Inflammatory Bowel Diseases, 16(7), 1203-1208. Read abstract.

Mascarenhas MR, & Thayu M. (2010). Pediatric inflammatory bowel disease and bone health. Nutrition in Clinical Practice, 25(4), 347-352. Read abstract.

Thayu M, Denson LA, Shults J, Zemel BS, Burnham JM, Baldassano RN, ... & Leonard MB. (2010). Determinants of changes in linear growth and body composition in incident pediatric Crohn's disease. Gastroenterology, 139(2), 430-438. Read abstract.

Wang K, Baldassano R, Zhang H, Qu HQ, Imielinski M, Kugathasan S, ... & Hakonarson, H. (2010). Comparative genetic analysis of inflammatory bowel disease and type 1 diabetes implicates multiple loci with opposite effects. Human Molecular Genetics, 19(10), 2059-2067. Read abstract.

Ingerski LM, Baldassano RN, Denson LA, Hommel KA. (2009) Barriers to oral medication adherence for adolescents with inflammatory bowel disease. Journal of Pediatric Psychology, 1-9. Read abstract.

Gupta N, Bostrom AG, Kirschner BS, Ferry GD, Gold BD, Cohen SA, et al. (2009). Incidence of stricturing and penetrating complications of Crohn's disease diagnosed in pediatric patients. Inflammatory Bowel Diseases, 2009 Sept. 6 (Epub ahead of print) Read abstract.

Wang K, Zhang H, Kugathasan S, Annese V, Bradfield JP, Russell RK, (2009). Diverse genome-wide association studies associate the IL12/IL23 pathway with Crohn Disease. American Journal of Human Genetics, 84, 399 -405. Read abstract.

Colletti RB, Baldassano RN, Milov DE, Margolis PA, Bousvaros A, Crandall WV, et al. (2009). Variation in care in pediatric Crohn's disease. Journal of Pediatric Gastroenterology and Nutrition, 49(3), 297–303. Read abstract.

Crandall W, Hyams J, Kugathasan S, Griffiths A, Zrubek J, Olson A, et al. (2009). Infliximab therapy in children With concurrent perianal Crohn's disease: observations from REACH. Journal of Pediatric Gastroenterology and Nutrition, 49(2), 183–190. Read abstract.

Liu S, Russo PA, Baldassano RN, Sullivan KE. (2009). CD68 expression is markedly different in Crohn's disease and the colitis associated with chronic granulomatous disease. Inflammatory Bowel Disease, 15, 1213-1217. Read abstract.

Miele E, Pascarella F, Giannetti E, Quaglietta L, Baldassano RN, Staiano A. (2009) Effect of a probiotic preparation (VSL#3) on induction and maintenance of remission in children with ulcerative colitis. American Journal of Gastroenterology, 104:437–443. Read abstract.

Heyman MB, Garnett EA, Shaikh N, Huen K, Jose FA, Harmatz P, Winter HS, et al. (2009) Folate concentrations in pediatric patients with newly diagnosed inflammatory bowel disease. American Journal of Clinical Nutrition, 89, 545-550. Read abstract.

Dubner SE, Shults J, Baldassano RN, Zemel BS, Thayu M, Burnham JM, et al. (2009). Longitudinal assessment of bone density and structure in an incident cohort of children with Crohn's disease. Gastroenterology, 136, 123 -130. Read abstract.

Hommel KA, Davis CM, Baldassano RN. (2009). Objective versus subjective assessment of oral medication adherence in pediatric inflammatory bowel disease. Inflammatory Bowel Disease, 15, 589-59. Read abstract.

Jose FA, Garnett EA, Vittinghoff E, Ferry GD, Winter HS, Baldassano RN, et al. (2009). Development of extraintestinal manifestations in pediatric patients with inflammatory bowel disease. Inflammatory Bowel Disease, 15, 63-68. Read abstract.

Imielinski M, Baldassano RN, Griffiths A, Russell RK, Annese V, Dubinsky M, Kugathasan S, Bradfield JP, Walters TD, Sleiman P, Kim CE, Muise A, Wang K, Glessner JT, Saeed S, Zhang H, Frackelton EC, Hou C, Flory JH, Otieno G, Chiavacci RM, Grundmeier R, Castro M, Latiano A, Dallapiccola B, Stempak J, Abrams DJ, Taylor K, McGovern D; Western Regional Research Alliance for Pediatric IBD; International IBD Genetics Consortium, Heyman MB, Ferry GD, Kirschner B, Lee J, Essers J, Grand R, Stephens M, Levine A, Piccoli D, Van Limbergen J, Cucchiara S, Monos DS, Guthery SL, Denson L, Wilson DC, Grant SF, Daly M, Silverberg MS, Satsangi J, Hakonarson H. (2009) Common variants at five new loci associated with early-onset inflammatory bowel disease. National Genetics, Nov 15. [Epub ahead of print] Read abstract.

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