ICU and Inpatient Clinical Pathway for Inpatient Management of Infants ≤ 56 days or Preterm Infants with Corrected Gestational Age (CGA) of ≤ 48 weeks with Suspected or Confirmed UTI Diagnosis
UTI Confirmed
Antibiotic Strategy
  • Broad-spectrum antibiotics until culture sensitivities available
  • Recommended 10-day total course
Diagnostic Imaging and Prophylactic Antibiotics
  • Renal Bladder Ultrasound (RBUS)
First UTI with NORMAL RBUS in preterm infants or NICU patients
First UTI with NORMAL RBUS in healthy, full term infants on IP units
First UTI with ABNORMAL RBUS
or ≥ 2nd UTI
  • Urology consult
  • Obtain Voiding Cysto-Urethrogram (VCUG)
  • Consider Prophylaxis
Discharge Plan
  • Urology follow up based on consult recommendations
  • Discuss potential benefit of circumcision, prior to discharge
  • Parent Education
  • Home Instructions
Posted: March 2020
Revised: August 2020
Authors: E. Brandsma, MD; T. Kolon, MD; S. Coffin, MD; L. Goldsmith, MD; D. Flannery, MD; J. Burns, MD; J. Hart, MD