Education and Training
MD, Dartmouth Medical School, Hanover, NH
General Surgery, Massachusetts General Hospital, Boston, MA
General Surgery, Massachusetts General Hospital, Boston, MA
Critical Care Fellow, Warren G. Magnuson Clinical Center, National Institutes of Health, Bethesda, MD
Senior Research Fellow, Warren G. Magnuson Clinical Center, National Institutes of Health, Bethesda, MD
Research Fellow, Department of Surgery, Ma
Pediatric Surgery – American Board of SurgeryGeneral Surgery – American Board of SurgerySurgical Critical Care – American Board of Surgery
BA, Political Science, Wellesley College, Wellesley, MA
MHSc, Clinical Research, Duke University, Durham, NC
Titles and Academic Titles
Assistant Professor of Surgery, Perelman School of Medicine at the University of Pennsylvania
Ongoing Research Protocols
Co-Investigator; Children’s Hospital of Philadelphia Human Research Protocol IRB #2007-10-5512: Characterization of the levels and effects of intravascular hemolysis in patients undergoing cardiopulmonary bypass.
Co-Investigator; Children’s Hospital of Philadelphia Human Research Protocol IRB #2007-8-5451: Characterization of the levels and effects of intravascular hemolysis in patients undergoing extracorporeal membrane oxygenation.
Co-Investigator; University of Pennsylvania Human Research Protocol IRB #806867: Characterization of the levels and effects of intravascular hemolysis in patients undergoing cardiopulmonary bypass.
Co-Investigator; National Institutes of Health Animal Protocol ASP#CCM04-XX: The effect of glucocorticoids in a sedated and ventilated model of canine sepsis.
Deans KJ, Minneci PC, Klein HG, Natanson C. The relevance of practice misalignments to trials in transfusion medicine. Vox Sang. 2010 Jul 1;99(1):16-23. Epub 2010 Mar 21.
Deans KJ, Minneci PC. ACP Journal Club. Intensive insulin therapy did not reduce mortality more than conventional therapy in septic shock treated with corticosteroids. Ann Intern Med. 2010.
Deans KJ, Minneci PC, Klein HG, Natanson C. The relevance of practice misalignments to trials in transfusion medicine. Vox Sang. 2010.
Deans KJ, Minneci PC, Danner RL, Eichacker PQ, Natanson C. Practice Misalignments in Randomized Controlled Trials: Identification, Impact and Potential Solutions. Anesth Anal. 2010.
Minneci PC, Deans KJ, Natanson C. Corticosteroid therapy for severe sepsis and septic shock. JAMA. 2009;302(15):643.
Deans KJ, Minneci PC, Chen H, Kern SJ, Logun C, Alsaaty S, Norsworthy KJ, Theel SM, Sennesh JD, Barb JJ, Munson PJ, Danner RL, Solomon MA. Impact of Animal Strain on Gene Expression in a Rat Model of Acute Cardiac Rejection. BMC Genomics 2009;10:280.
Minneci PC, Deans KJ, Eichacker PQ, Natanson C. The Effects of Steroids during Sepsis Depend on Dose and Severity of Illness: An Updated Meta-analysis. Clin Microbiol Infect.. 2009; 15(4):308-18.
Solomon SB, Minneci PC, Deans KJ, et al. Effects of Intra-aortic Balloon Counterpulsation in a Model of Septic Shock. Crit Care Med 2009;37:7-18.
Deans KJ, Minneci PC, Shiva S, Zhi H, Banks SM, Kearns S, Natanson C, Solomon SB, Gladwin MT. Nitrite Reductase Activity of Hemoglobin: A systemic nitric oxide delivery mechanism to detoxify cell free plasma hemoglobin? Am J Physiol Heart Circ Physiol.2008;295:H743-754.
Minneci PC, Eichacker PQ, Danner RL, Banks SM, Natanson C, Deans KJ. The Importance of Usual Care Control Groups for Safety Monitoring and Validity during Critical Care Research. Intensive Care Med. 2008;34:942-947.
Deans KJ, Minneci PC, Suffredini AF, et al. Randomization in Clinical Trials of Titrated Therapies: Unintended Consequences of Using Fixed Treatment Protocols. Crit Care Med. 2007; 2007;35(6):1509-1516.
Minneci PC, Deans KJ, Banks SM, et al. A Canine Model of Septic Shock: Balancing Animal Welfare and Scientific Relevance. Am J Physiol Heart Circ Physiol. 2007;293(4):H2487-500.
Minneci PC, Deans KJ, Xizhong C, Banks SM, Natanson C, Eichacker PQ. Antithrombotic Therapies for Sepsis: A Need for More Studies. Crit Care Med. 2006;34(2)538-541.
Deans KJ, Minneci PC, Banks SM, Xizhong C, Natanson C, Eichacker PQ. Mechanical Ventilation in ARDS. Crit Care Med. 2006;34(1):263-267.
Santore M, Behar BJ, Flake AW, Deans KJ. Laparoscopic hepaticoduodenostomy for choledochal cyst excision and reconstruction. Accepted for oral presentation at American Pediatric Surgical Association National Meeting, Orlando, FL. May, 2010.
Kilbaugh TJ, Topjian AA, Chandler HK, Hedrick HL, McCloskey JM, Deans KJ. Influenza A (H1N1) and MRSA acute respiratory distress syndrome and cardiogenic shock supported with Extracorporeal Membrane Oxygenation and Plasmapheresis. CNMC Symposium: ECMO & the Advanced Therapies for Respiratory Failure. 2010. A40.
Behar B, Minneci PC, Kilbaugh TJ, Hedrick HL, Deans KJ. Variables associated with increased mortality on pediatric patients requiring Extracorporeal Life Support for a primary diagnosis of pneumonia. CNMC Symposium: ECMO & the Advanced Therapies for Respiratory Failure. 2010. A55.
Minneci PC, Deans KJ, Banks SM, Eichacker PQ, Natanson C. Dose Dependent Effects of Steroids on Survival Rates and Shock during Sepsis: A Meta-analysis. Crit Care Med. 2003;31:A20.
Minneci PC, Deans KJ, Natanson C. Applying the Results of Randomized Controlled Trials: Caveat Emptor. In: Chiche JD, Moreno R, Putensen C, Rhodes A, eds. Patient Safety and Quality of Care in Intensive Care Medicine. Berlin: MWV Medizinisch Wissenschaftliche. 2010.
Deans, KJ. Gastrointestinal Bleeding. In: Mattei P, ed. Fundamentals of Pediatric Surgery. New York: Springer. 2010.
Deans KJ, Minneci PC, Cui X, Banks SM, Natanson C, Eichacker PQ. The Need to Account for Existing Practice Patterns in Trials of Mechanical Ventilation. In: Tobin MJ, eds. Principles and Practice of Mechanical Ventilation,. 2nd edition. New York: McGraw Hill. 2006:1347-1354.
Minneci PC, Deans KJ, Banks SM, Natanson C, Eichacker PQ. A Critical Review of Randomized Controlled Trials of Tidal Volume Reduction During ARDS. In: Dreyfuss D, Hubmayr RD, Saumon G, eds. Ventilator Induced Lung Injury. New York: Marcel Dekker, Inc.; 2006:519-536.
Minneci PC, Deans KJ, Haley M, Xizhong C, Natanson C, Eichacker PQ. Factors Influencing the Efficacy of Mediator-Specific Anti-inflammatory, Glucocorticoid and Anti-Coagulant Therapies for Sepsis. In: Gad SC, ed. Drug Discovery Handbook. Vol 1. Hoboken: Wiley Interscience; 2005:937-960.
Deans K, Minneci P, Eichacker PQ, Natanson C. Anti-Inflammatory Agents: A Double Edged Sword in Our Arsenal Against Septic Shock. In: Net A, ed. Shock and Multiorgan Failure. 2003 ed. Iberica: Springer-Verlag; 2003:pp.
Patient Experience Ratings
About the Patient Experience Rating System
The Patient Experience Rating is an average of all responses to the care provider related questions shown above from our nationally-recognized Press Ganey Patient Satisfaction Survey. Patients that are treated in outpatient or hospital environments may receive different surveys, and the volume of responses will vary by question.
Responses are measured on a scale of 1 to 5 with 5 being the best score.
We are committed to true transparency. However, to ensure the comments are fair and correctly attributed, we review each one before posting to the website. We exclude entire comments that disclose patient's protected health information, are off-topic, or include other confidential or inappropriate content. Comments will appear on provider bios only if providers have a minimum number of comments.
Comments are shared internally for education purposes to ensure that we are doing our very best for the patients and families for whom we are privileged to care.
The comments are submitted by patients and families and reflect their views and opinions. The comments are not endorsed by and do not reflect the views of Children’s Hospital of Philadelphia.